PMID- 10377239
OWN - NLM
STAT- MEDLINE
DCOM- 19990903
LR  - 20181113
IS  - 0264-6021 (Print)
IS  - 0264-6021 (Linking)
VI  - 341 ( Pt 1)
DP  - 1999 Jul 1
TI  - A conserved RGD (Arg-Gly-Asp) motif in the transferrin receptor is required for
      binding to transferrin.
PG  - 11-4
AB  - The transferrin receptor contains a highly conserved Arg-Gly-Asp (RGD) sequence
      in the C-terminal region where transferrin is thought to bind. RGD sequences are 
      commonly involved in cell adhesion. This sequence is crucial for transferrin
      binding, suggesting possible evolutionary links between molecules mediating iron 
      uptake and cell adhesion.
FAU - Dubljevic, V
AU  - Dubljevic V
AD  - Department of Pathology and Immunology, Monash Medical School, Alfred Hospital,
      Prahran, Victoria 3181, Australia.
FAU - Sali, A
AU  - Sali A
FAU - Goding, J W
AU  - Goding JW
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Biochem J
JT  - The Biochemical journal
JID - 2984726R
RN  - 0 (Oligopeptides)
RN  - 0 (Receptors, Transferrin)
RN  - 0 (Recombinant Fusion Proteins)
RN  - 0 (Transferrin)
RN  - 78VO7F77PN (arginyl-glycyl-aspartic acid)
RN  - EC 3.1.3.1 (Alkaline Phosphatase)
SB  - IM
MH  - Alkaline Phosphatase/genetics
MH  - *Amino Acid Sequence
MH  - *Conserved Sequence
MH  - Humans
MH  - Molecular Sequence Data
MH  - *Oligopeptides
MH  - Protein Binding
MH  - Receptors, Transferrin/genetics/*metabolism
MH  - Recombinant Fusion Proteins/metabolism
MH  - Sequence Homology, Amino Acid
MH  - Transferrin/*metabolism
PMC - PMC1220324
EDAT- 1999/06/23 00:00
MHDA- 1999/06/23 00:01
CRDT- 1999/06/23 00:00
PHST- 1999/06/23 00:00 [pubmed]
PHST- 1999/06/23 00:01 [medline]
PHST- 1999/06/23 00:00 [entrez]
PST - ppublish
SO  - Biochem J. 1999 Jul 1;341 ( Pt 1):11-4.