PMID- 10376216
OWN - NLM
STAT- MEDLINE
DCOM- 19990913
LR  - 20191024
IS  - 1042-5179 (Print)
IS  - 1026-7913 (Linking)
VI  - 10
IP  - 2
DP  - 1999
TI  - Unique 5'-end of a Na(+)-K(+)-2Cl- cotransporter-like mRNA expressed in rat
      skeletal muscle.
PG  - 127-32
AB  - Functional evidence presented by others indicates that rat slow-twitch skeletal
      muscle lacks typical Na(+)-K(+)-2Cl- cotransporter activity, as determined by
      loop diuretic-sensitive potassium transport. This report presents a unique 5'
      mRNA sequence of a Na(+)-K(+)-2Cl- cotransporter-like molecule expressed in the
      rat soleus muscle and the deduced N-terminus of the protein. In addition to its
      unique 5' mRNA sequence, the coding region of the N-terminus is quite short
      compared with other known Na(+)-K(+)-2Cl- cotransporters. Nonetheless, the mRNA
      possesses conserved cotransporter-like membrane spanning domains, though one
      domains corresponding to a reported exon is divergent. Therefore, it appears that
      skeletal muscle does express a Na(+)-K(+)-2Cl- cotransporter-like mRNA that may
      code for a protein with atypical Na(+)-K(+)-2Cl- cotransporter properties.
FAU - Fu, L
AU  - Fu L
AD  - Department of Physiology, University of Tennessee, Memphis 38163, USA.
FAU - Wong, J A
AU  - Wong JA
FAU - Schneider, E G
AU  - Schneider EG
FAU - Thomason, D B
AU  - Thomason DB
LA  - eng
SI  - GENBANK/AF086758
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - DNA Seq
JT  - DNA sequence : the journal of DNA sequencing and mapping
JID - 9107800
RN  - 0 (Carrier Proteins)
RN  - 0 (DNA, Complementary)
RN  - 0 (RNA, Messenger)
RN  - 0 (Sodium-Potassium-Chloride Symporters)
SB  - IM
MH  - Amino Acid Sequence
MH  - Animals
MH  - Base Sequence
MH  - Carrier Proteins/biosynthesis/*genetics
MH  - DNA, Complementary
MH  - Molecular Sequence Data
MH  - Muscle, Skeletal/*metabolism
MH  - *RNA, Messenger/chemistry
MH  - Rats
MH  - Sequence Homology, Amino Acid
MH  - Sequence Homology, Nucleic Acid
MH  - Sodium-Potassium-Chloride Symporters
EDAT- 1999/06/22 10:00
MHDA- 2000/08/12 11:00
CRDT- 1999/06/22 10:00
PHST- 1999/06/22 10:00 [pubmed]
PHST- 2000/08/12 11:00 [medline]
PHST- 1999/06/22 10:00 [entrez]
AID - I307J981057 [pii]
AID - 10.3109/10425179909008430 [doi]
PST - ppublish
SO  - DNA Seq. 1999;10(2):127-32. doi: 10.3109/10425179909008430.