PMID- 10350627
OWN - NLM
STAT- MEDLINE
DCOM- 19990712
LR  - 20190610
IS  - 0006-3002 (Print)
IS  - 0006-3002 (Linking)
VI  - 1431
IP  - 2
DP  - 1999 May 18
TI  - cDNA sequence, mRNA expression, and chromosomal localization of human carbonic
      anhydrase-related protein, CA-RP XI.
PG  - 518-24
AB  - A full-length cDNA clone of a human carbonic anhydrase-related protein, CA-RP XI 
      encoded by CA11, was obtained and sequenced. The cDNA sequence was 1475 bp long
      and predicted to encode a 328-amino acid polypeptide with a molecular mass of
      36200 Da. The deduced amino acid sequence of CA-RP XI showed an overall
      similarity of 42-53% to the active site residues of other active CA isozymes;
      however, it lacked three zinc-binding histidine residues, raising questions
      regarding its CA catalytic activity. Northern blot analysis demonstrated strong
      expression of an approx. 1.5 kb transcript in the human brain, particularly in
      the cerebellum, cerebral cortex, and putamen. A single copy of the CA11 gene was 
      localized to the human chromosome 19q13.2-3. These results suggest that CA-RP XI 
      plays a general role in the human central nervous system.
FAU - Fujikawa-Adachi, K
AU  - Fujikawa-Adachi K
AD  - First Department of Internal Medicine, Kochi Medical School, Nankoku, Kochi
      783-8505, Japan.
FAU - Nishimori, I
AU  - Nishimori I
FAU - Taguchi, T
AU  - Taguchi T
FAU - Yuri, K
AU  - Yuri K
FAU - Onishi, S
AU  - Onishi S
LA  - eng
SI  - GENBANK/AB018195
PT  - Comparative Study
PT  - Journal Article
PL  - Netherlands
TA  - Biochim Biophys Acta
JT  - Biochimica et biophysica acta
JID - 0217513
RN  - 0 (CA11 protein, human)
RN  - 0 (DNA, Complementary)
RN  - 0 (Nerve Tissue Proteins)
RN  - 0 (RNA, Messenger)
RN  - EC 4.2.1.1 (Carbonic Anhydrases)
SB  - IM
MH  - Amino Acid Sequence
MH  - Base Sequence
MH  - *Carbonic Anhydrases
MH  - Chromosome Mapping
MH  - DNA, Complementary/chemistry/*genetics
MH  - Humans
MH  - Molecular Sequence Data
MH  - Nerve Tissue Proteins/analysis/*genetics/metabolism
MH  - RNA, Messenger/biosynthesis
MH  - Sequence Alignment
EDAT- 1999/06/03 00:00
MHDA- 1999/06/03 00:01
CRDT- 1999/06/03 00:00
PHST- 1999/06/03 00:00 [pubmed]
PHST- 1999/06/03 00:01 [medline]
PHST- 1999/06/03 00:00 [entrez]
AID - S0167-4838(99)00067-9 [pii]
AID - 10.1016/s0167-4838(99)00067-9 [doi]
PST - ppublish
SO  - Biochim Biophys Acta. 1999 May 18;1431(2):518-24. doi:
      10.1016/s0167-4838(99)00067-9.