PMID- 10338144
OWN - NLM
STAT- MEDLINE
DCOM- 19990615
LR  - 20190621
IS  - 0014-5793 (Print)
IS  - 0014-5793 (Linking)
VI  - 449
IP  - 2-3
DP  - 1999 Apr 23
TI  - pADPRT-2: a novel mammalian polymerizing(ADP-ribosyl)transferase gene related to 
      truncated pADPRT homologues in plants and Caenorhabditis elegans.
PG  - 259-63
AB  - Until recently, poly(ADP-ribosyl)ation was supposed to be confined only to
      polymerizing(ADP-ribosyl)transferase/(ADP-ribose)polymerase (E.C. 2.4.2.30).
      Here, we present novel polymerizing(ADP-ribosyl)transferase homologues from mouse
      and man that lack all of the N-terminal DNA binding and BRCA1 C-terminus domains 
      and will be designated polymerizing(ADP-ribosyl)transferase-2 as distinguished
      from the classical polymerizing(ADP-ribosyl)transferase
      (polymerizing(ADP-ribosyl)transferase-1). The murine
      polymerizing(ADP-ribosyl)transferase-2 gene shares three identical intron
      positions with its Caenorhabditis elegans (EMBL nucleotide sequence database
      Z47075) and one with the Arabidopsis thaliana homologue ('APP', GenBank database 
      AF069298). Expression of the murine polymerizing(ADP-ribosyl)transferase-2 gene
      was elevated in spleen, thymus and testis and the corresponding
      poly(ADP-ribosyl)ation activity might account for most of the residual
      poly(ADP-ribosyl)ation observed in polymerizing(ADP-ribosyl)transferase-1(-/-)
      mice.
FAU - Berghammer, H
AU  - Berghammer H
AD  - Institute of Biochemistry, University of Innsbruck, Austria.
FAU - Ebner, M
AU  - Ebner M
FAU - Marksteiner, R
AU  - Marksteiner R
FAU - Auer, B
AU  - Auer B
LA  - eng
SI  - GENBANK/AF072521
SI  - GENBANK/AJ236876
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - FEBS Lett
JT  - FEBS letters
JID - 0155157
RN  - 0 (DNA, Complementary)
RN  - EC 2.4.2.30 (Poly(ADP-ribose) Polymerases)
SB  - IM
MH  - Amino Acid Sequence
MH  - Animals
MH  - Arabidopsis/*enzymology/genetics
MH  - Base Sequence
MH  - Caenorhabditis elegans/*enzymology/genetics
MH  - Conserved Sequence
MH  - DNA, Complementary
MH  - Humans
MH  - Introns
MH  - Mammals
MH  - Mice
MH  - Mice, Knockout
MH  - Molecular Sequence Data
MH  - Multigene Family
MH  - Poly(ADP-ribose) Polymerases/*genetics
MH  - Sequence Homology, Amino Acid
MH  - Tissue Distribution
MH  - Transcription, Genetic
EDAT- 1999/05/25 00:00
MHDA- 1999/05/25 00:01
CRDT- 1999/05/25 00:00
PHST- 1999/05/25 00:00 [pubmed]
PHST- 1999/05/25 00:01 [medline]
PHST- 1999/05/25 00:00 [entrez]
AID - S0014-5793(99)00448-2 [pii]
AID - 10.1016/s0014-5793(99)00448-2 [doi]
PST - ppublish
SO  - FEBS Lett. 1999 Apr 23;449(2-3):259-63. doi: 10.1016/s0014-5793(99)00448-2.