PMID- 10330503
OWN - NLM
STAT- MEDLINE
DCOM- 19990720
LR  - 20190909
IS  - 0925-4773 (Print)
IS  - 0925-4773 (Linking)
VI  - 81
IP  - 1-2
DP  - 1999 Mar
TI  - Cloning and expression pattern of a mouse homologue of drosophila sprouty in the 
      mouse embryo.
PG  - 213-6
AB  - Signaling molecules belonging to the Fibroblast growth factor (Fgf) family are
      necessary for directing bud outgrowth during tracheal development in Drosophila
      and lung development in mouse. A potential inhibitor of the Fgf signaling
      pathway, called Sprouty, has been identified in Drosophila. We have identified
      three potential mouse homologues of sprouty. One of them, called Sprouty4,
      exhibits a very restricted expression pattern. At 8.0 dpc (days post coitum)
      Sprouty4 is strongly expressed in the primitive streak region. At 9. 5 and 10.5
      dpc, Sprouty4 is expressed in the nasal placode, the maxillary and mandibular
      processes, the otic vesicule, the second branchial arch, in the progress region
      of the limb buds and the presomitic mesoderm. Sprouty4 expression is also
      detected in the lateral region of the somites. In the developing lung, Sprouty4
      is expressed broadly in the distal mesenchyme.
FAU - de Maximy, A A
AU  - de Maximy AA
AD  - Institut Curie-UMR 144 CNRS, 26 rue d'Ulm, 75248, Paris Cedex 05, France.
FAU - Nakatake, Y
AU  - Nakatake Y
FAU - Moncada, S
AU  - Moncada S
FAU - Itoh, N
AU  - Itoh N
FAU - Thiery, J P
AU  - Thiery JP
FAU - Bellusci, S
AU  - Bellusci S
LA  - eng
SI  - GENBANK/AB019280
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Ireland
TA  - Mech Dev
JT  - Mechanisms of development
JID - 9101218
RN  - 0 (Drosophila Proteins)
RN  - 0 (Insect Proteins)
RN  - 0 (Membrane Proteins)
RN  - 0 (sty protein, Drosophila)
SB  - IM
MH  - Amino Acid Sequence
MH  - Animals
MH  - Cloning, Molecular
MH  - Databases, Factual
MH  - Drosophila/*embryology
MH  - *Drosophila Proteins
MH  - In Situ Hybridization
MH  - Insect Proteins/analysis/*metabolism
MH  - Lung/embryology
MH  - *Membrane Proteins
MH  - Mesoderm/metabolism
MH  - Mice
MH  - Molecular Sequence Data
MH  - Sequence Homology, Amino Acid
MH  - Time Factors
MH  - Tissue Distribution
EDAT- 1999/05/20 00:00
MHDA- 1999/05/20 00:01
CRDT- 1999/05/20 00:00
PHST- 1999/05/20 00:00 [pubmed]
PHST- 1999/05/20 00:01 [medline]
PHST- 1999/05/20 00:00 [entrez]
AID - S0925-4773(98)00241-X [pii]
AID - 10.1016/s0925-4773(98)00241-x [doi]
PST - ppublish
SO  - Mech Dev. 1999 Mar;81(1-2):213-6. doi: 10.1016/s0925-4773(98)00241-x.