PMID- 10330500 OWN - NLM STAT- MEDLINE DCOM- 19990720 LR - 20190909 IS - 0925-4773 (Print) IS - 0925-4773 (Linking) VI - 81 IP - 1-2 DP - 1999 Mar TI - Expression of the T-box gene Eomesodermin during early mouse development. PG - 199-203 AB - We report the expression pattern of a murine homolog of the Xenopus laevis T-box gene Eomesodermin. mEomes expression is first detected in the extra-embryonic ectoderm prior to gastrulation, and persists there until head-fold stages. In the embryo proper, mEomes is expressed throughout the early primitive streak, nascent mesoderm and in the anterior visceral endoderm. Although mEomes expression disappears from the embryo at late-streak stages, a second domain of mEomes expression is observed in the telencephalon beginning around E10.5. FAU - Ciruna, B G AU - Ciruna BG AD - Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario, Canada. FAU - Rossant, J AU - Rossant J LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - Ireland TA - Mech Dev JT - Mechanisms of development JID - 9101218 RN - 0 (Eomes protein, mouse) RN - 0 (Receptors, Fibroblast Growth Factor) RN - 0 (T-Box Domain Proteins) RN - 0 (Transcription Factors) RN - EC 2.7.10.1 (Fgfr2 protein, mouse) RN - EC 2.7.10.1 (Receptor Protein-Tyrosine Kinases) RN - EC 2.7.10.1 (Receptor, Fibroblast Growth Factor, Type 2) SB - IM MH - Animals MH - *Gene Expression Regulation, Developmental MH - Gene Library MH - In Situ Hybridization MH - Mice MH - Receptor Protein-Tyrosine Kinases/metabolism MH - Receptor, Fibroblast Growth Factor, Type 2 MH - Receptors, Fibroblast Growth Factor/metabolism MH - *T-Box Domain Proteins MH - Time Factors MH - Transcription Factors/analysis/*genetics EDAT- 1999/05/20 00:00 MHDA- 1999/05/20 00:01 CRDT- 1999/05/20 00:00 PHST- 1999/05/20 00:00 [pubmed] PHST- 1999/05/20 00:01 [medline] PHST- 1999/05/20 00:00 [entrez] AID - S0925-4773(98)00243-3 [pii] AID - 10.1016/s0925-4773(98)00243-3 [doi] PST - ppublish SO - Mech Dev. 1999 Mar;81(1-2):199-203. doi: 10.1016/s0925-4773(98)00243-3.