PMID- 10327278
OWN - NLM
STAT- MEDLINE
DCOM- 19990802
LR  - 20131121
IS  - 0957-9672 (Print)
IS  - 0957-9672 (Linking)
VI  - 10
IP  - 2
DP  - 1999 Apr
TI  - Defects in mitochondrial beta-oxidation of fatty acids.
PG  - 107-12
AB  - Mitochondrial beta-oxidation of fatty acids generates energy by direct electron
      transfer at the dehydrogenase steps along with the ultimate product of
      acetyl-coenzyme A that can be further oxidized for ATP synthesis, or conversion
      to ketone bodies. This review describes the human inborn errors of this pathway
      and recent results concerning the development and use of mouse models of these
      inherited enzyme deficiencies.
FAU - Wood, P A
AU  - Wood PA
AD  - Department of Comparative Medicine, School of Medicine, University of Alabama at 
      Birmingham 35294-0019, USA.
LA  - eng
GR  - R01-RR02599/RR/NCRR NIH HHS/United States
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PT  - Review
PL  - England
TA  - Curr Opin Lipidol
JT  - Current opinion in lipidology
JID - 9010000
RN  - 0 (Fatty Acids)
RN  - EC 1.14.19.- (Fatty Acid Desaturases)
RN  - EC 1.3.8.7 (Acyl-CoA Dehydrogenase)
SB  - IM
MH  - Acyl-CoA Dehydrogenase
MH  - Animals
MH  - Cold Temperature
MH  - Fatty Acid Desaturases/deficiency
MH  - Fatty Acids/genetics/*metabolism
MH  - Gene Expression Regulation, Enzymologic
MH  - Humans
MH  - Mice
MH  - Mitochondria/*metabolism
MH  - Models, Biological
RF  - 41
EDAT- 1999/05/18 00:00
MHDA- 1999/05/18 00:01
CRDT- 1999/05/18 00:00
PHST- 1999/05/18 00:00 [pubmed]
PHST- 1999/05/18 00:01 [medline]
PHST- 1999/05/18 00:00 [entrez]
PST - ppublish
SO  - Curr Opin Lipidol. 1999 Apr;10(2):107-12.