PMID- 10319407
OWN - NLM
STAT- MEDLINE
DCOM- 19990802
LR  - 20191024
IS  - 1039-9712 (Print)
IS  - 1039-9712 (Linking)
VI  - 47
IP  - 4
DP  - 1999 Apr
TI  - Expression of two dead box genes (DDX1 and DDX6) is independent of that of MYCN
      in human neuroblastoma cell lines.
PG  - 563-8
AB  - To examine whether two DEAD box genes, DDX1 and DDX6, would have some roles in
      the progression of tumors, we investigated the correlation of the expression of
      these genes with that of MYCN in neuroblastomas either with or without MYCN
      amplification. The mRNA of MYCN was observed only in the cell lines with
      amplification of MYCN. The mRNAs of DDX1 and DDX6 were found in all the cell
      lines examined, but the correlation between the mRNA levels of DDX1 or DDX6 and
      MYCN was poor. These findings suggest that the expression of neither DEAD box
      gene is correlated with the gene expression of MYCN.
FAU - Akiyama, K
AU  - Akiyama K
AD  - Pharmaceutical Frontiers Research Laboratories, Japan Tobacco, Inc., Yokohama.
FAU - Akao, Y
AU  - Akao Y
FAU - Yokoyama, M
AU  - Yokoyama M
FAU - Nakagawa, Y
AU  - Nakagawa Y
FAU - Noguchi, T
AU  - Noguchi T
FAU - Yagi, K
AU  - Yagi K
FAU - Nishi, Y
AU  - Nishi Y
LA  - eng
PT  - Journal Article
PL  - England
TA  - Biochem Mol Biol Int
JT  - Biochemistry and molecular biology international
JID - 9306673
RN  - 0 (Proto-Oncogene Proteins)
RN  - 0 (Proto-Oncogene Proteins c-myc)
RN  - EC 2.7.7.- (RNA Nucleotidyltransferases)
RN  - EC 3.6.1.- (DDX1 protein, human)
RN  - EC 3.6.1.- (DDX6 protein, human)
RN  - EC 3.6.4.13 (DEAD-box RNA Helicases)
RN  - EC 3.6.4.13 (RNA Helicases)
SB  - IM
MH  - DEAD-box RNA Helicases
MH  - *Gene Expression Regulation, Neoplastic
MH  - Humans
MH  - Neuroblastoma/*genetics
MH  - Proto-Oncogene Proteins/*genetics/metabolism
MH  - Proto-Oncogene Proteins c-myc/*genetics
MH  - RNA Helicases/*genetics
MH  - RNA Nucleotidyltransferases/*genetics/metabolism
MH  - Tumor Cells, Cultured
EDAT- 1999/05/13 00:00
MHDA- 1999/05/13 00:01
CRDT- 1999/05/13 00:00
PHST- 1999/05/13 00:00 [pubmed]
PHST- 1999/05/13 00:01 [medline]
PHST- 1999/05/13 00:00 [entrez]
AID - 10.1080/15216549900201603 [doi]
PST - ppublish
SO  - Biochem Mol Biol Int. 1999 Apr;47(4):563-8. doi: 10.1080/15216549900201603.