PMID- 102365 OWN - NLM STAT- MEDLINE DCOM- 19790212 LR - 20190609 IS - 0006-3002 (Print) IS - 0006-3002 (Linking) VI - 537 IP - 1 DP - 1978 Nov 20 TI - Amino acid sequence of the human myeloma lambda chain Win. PG - 9-21 AB - The complete amino acid sequence of the variable region of a human myeloma immunoglobulin light chain (Win) has been determined. The sequence of the constant region has been verified by compositional analysis of its tryptic peptides. The amino acid sequence of the light chain Win corresponds to sub group II and shows no unusual amino acid replacements in its constant or variable regions when compared to other human gamma chains. FAU - Chen, B L AU - Chen BL FAU - Chiu, Y Y AU - Chiu YY FAU - Humphrey, R L AU - Humphrey RL FAU - Poljak, R J AU - Poljak RJ LA - eng PT - Journal Article PT - Research Support, U.S. Gov't, P.H.S. PL - Netherlands TA - Biochim Biophys Acta JT - Biochimica et biophysica acta JID - 0217513 RN - 0 (Immunoglobulin Light Chains) RN - 0 (Myeloma Proteins) RN - 0 (Peptide Fragments) RN - EC 3.4.21.4 (Trypsin) SB - IM MH - Amino Acid Sequence MH - Humans MH - *Immunoglobulin Light Chains MH - Molecular Weight MH - *Myeloma Proteins MH - Peptide Fragments/analysis MH - Trypsin EDAT- 1978/11/20 00:00 MHDA- 1978/11/20 00:01 CRDT- 1978/11/20 00:00 PHST- 1978/11/20 00:00 [pubmed] PHST- 1978/11/20 00:01 [medline] PHST- 1978/11/20 00:00 [entrez] AID - 0005-2795(78)90598-6 [pii] AID - 10.1016/0005-2795(78)90598-6 [doi] PST - ppublish SO - Biochim Biophys Acta. 1978 Nov 20;537(1):9-21. doi: 10.1016/0005-2795(78)90598-6.