PMID- 10218586 OWN - NLM STAT- MEDLINE DCOM- 19990517 LR - 20190621 IS - 0014-5793 (Print) IS - 0014-5793 (Linking) VI - 447 IP - 1 DP - 1999 Mar 19 TI - Eos: a novel member of the Ikaros gene family expressed predominantly in the developing nervous system. PG - 76-80 AB - We identified a novel member of the Ikaros gene family, which has critical roles in the development of lymphoid lineages. This gene, which we named Eos, was expressed predominantly in the developing central and peripheral nervous system. Eos protein could interact with itself and Ikaros protein through its C-terminal portion in the yeast two hybrid assay. These findings suggested that Eos may have important roles in neural development similarly to the Ikaros family in the development of hemolymphoid tissue. FAU - Honma, Y AU - Honma Y AD - Department of Cell Science, Institute of Biomedical Sciences, Fukushima Medical University School of Medicine, Fukushima City, Japan. FAU - Kiyosawa, H AU - Kiyosawa H FAU - Mori, T AU - Mori T FAU - Oguri, A AU - Oguri A FAU - Nikaido, T AU - Nikaido T FAU - Kanazawa, K AU - Kanazawa K FAU - Tojo, M AU - Tojo M FAU - Takeda, J AU - Takeda J FAU - Tanno, Y AU - Tanno Y FAU - Yokoya, S AU - Yokoya S FAU - Kawabata, I AU - Kawabata I FAU - Ikeda, H AU - Ikeda H FAU - Wanaka, A AU - Wanaka A LA - eng SI - GENBANK/AB017615 PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - England TA - FEBS Lett JT - FEBS letters JID - 0155157 RN - 0 (Carrier Proteins) RN - 0 (DNA-Binding Proteins) RN - 0 (Nerve Tissue Proteins) RN - 0 (RNA, Messenger) RN - 0 (Transcription Factors) RN - 0 (Zfpn1a1 protein, mouse) RN - 0 (Zfpn1a4 protein, mouse) RN - 148971-36-2 (Ikaros Transcription Factor) SB - IM MH - Amino Acid Sequence MH - Animals MH - Astrocytes/cytology MH - Carrier Proteins/*genetics/isolation & purification MH - Central Nervous System/chemistry MH - *DNA-Binding Proteins MH - Ikaros Transcription Factor MH - In Situ Hybridization MH - Mice MH - Mice, Inbred ICR MH - Molecular Sequence Data MH - *Multigene Family MH - Nerve Tissue Proteins/*genetics/isolation & purification MH - Peripheral Nervous System/chemistry MH - Protein Binding MH - RNA, Messenger/isolation & purification MH - Sequence Homology, Amino Acid MH - Tissue Distribution MH - Transcription Factors/genetics/metabolism MH - Zinc Fingers/*genetics EDAT- 1999/04/28 00:00 MHDA- 1999/04/28 00:01 CRDT- 1999/04/28 00:00 PHST- 1999/04/28 00:00 [pubmed] PHST- 1999/04/28 00:01 [medline] PHST- 1999/04/28 00:00 [entrez] AID - S0014579399002653 [pii] AID - 10.1016/s0014-5793(99)00265-3 [doi] PST - ppublish SO - FEBS Lett. 1999 Mar 19;447(1):76-80. doi: 10.1016/s0014-5793(99)00265-3.