PMID- 1021593
OWN - NLM
STAT- MEDLINE
DCOM- 19770512
LR  - 20190509
IS  - 0022-1503 (Print)
IS  - 0022-1503 (Linking)
VI  - 67
IP  - 6
DP  - 1976 Nov-Dec
TI  - Random determination of a developmental process: reversal of normal visceral
      asymmetry in the mouse.
PG  - 336-8
AB  - Situs inversus viscerum in the mouse has been shown to be inherited as an
      autosomal recessive trait (gene symbol iv) with reduced penetrance. It is
      hypothesized that the normal allele at the iv locus exhibits complete dominance
      and controls normal visceral asymmetry. Absence of this control allows the situs 
      of visceral asymmetry to be determined in a random fashion. This hypothesis also 
      appears to apply to the inheritance of situs inversus in man and to the
      experimental production of situs inversus.
FAU - Layton, W M Jr
AU  - Layton WM Jr
LA  - eng
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - J Hered
JT  - The Journal of heredity
JID - 0375373
SB  - IM
MH  - Animals
MH  - Female
MH  - *Genes, Recessive
MH  - Heterozygote
MH  - Homozygote
MH  - Male
MH  - Mice/*physiology
MH  - Situs Inversus/epidemiology/*genetics
EDAT- 1976/11/11 19:15
MHDA- 2001/03/28 10:01
CRDT- 1976/11/11 19:15
PHST- 1976/11/11 19:15 [pubmed]
PHST- 2001/03/28 10:01 [medline]
PHST- 1976/11/11 19:15 [entrez]
AID - 10.1093/oxfordjournals.jhered.a108749 [doi]
PST - ppublish
SO  - J Hered. 1976 Nov-Dec;67(6):336-8. doi: 10.1093/oxfordjournals.jhered.a108749.