PMID- 10208750
OWN - NLM
STAT- MEDLINE
DCOM- 19990601
LR  - 20061115
IS  - 0012-1606 (Print)
IS  - 0012-1606 (Linking)
VI  - 209
IP  - 1
DP  - 1999 May 1
TI  - bves: A novel gene expressed during coronary blood vessel development.
PG  - 159-71
AB  - We have used a subtractive method to clone novel messages enriched in the heart. 
      Here we show that one such message, bves (blood vessel/epicardial substance) is a
      novel protein that is highly conserved between chicken and mouse. The bves
      message is detected at high levels in early chick hearts. Using anti-Bves
      antibodies, we show expression in cells of the proepicardial organ, migrating
      epicardium, epicardial-derived mesenchyme, and smooth muscle of the developing
      intracardiac arterial system, including the coronary arteries. Our data suggest
      that Bves is an early marker of developing vascular smooth muscle cells. In
      addition, the expression pattern of Bves protein reveals the patterning of
      intracardiac vascular smooth muscle and possible insights into the cellular
      regulation of smooth muscle differentiation during vasculogenesis.
CI  - Copyright 1999 Academic Press.
FAU - Reese, D E
AU  - Reese DE
AD  - Program for Developmental Biology, Vanderbilt University, Nashville, Tennessee
      37232-6400, USA.
FAU - Zavaljevski, M
AU  - Zavaljevski M
FAU - Streiff, N L
AU  - Streiff NL
FAU - Bader, D
AU  - Bader D
LA  - eng
SI  - GENBANK/AF124510
SI  - GENBANK/AF124511
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Dev Biol
JT  - Developmental biology
JID - 0372762
RN  - 0 (Actins)
RN  - 0 (Avian Proteins)
RN  - 0 (Bves protein, Gallus gallus)
RN  - 0 (Bves protein, mouse)
RN  - 0 (Cell Adhesion Molecules)
RN  - 0 (Muscle Proteins)
SB  - IM
MH  - Actins/metabolism
MH  - Amino Acid Sequence
MH  - Animals
MH  - Aorta/metabolism
MH  - Avian Proteins
MH  - Blotting, Northern
MH  - Blotting, Western
MH  - *Cell Adhesion Molecules
MH  - Chick Embryo
MH  - Coronary Vessels/*embryology/*metabolism
MH  - Gene Library
MH  - Mice
MH  - Molecular Sequence Data
MH  - Muscle Proteins/*genetics/physiology
MH  - Muscle, Smooth/metabolism
MH  - Muscle, Smooth, Vascular/metabolism
MH  - Myocardium/metabolism
MH  - Pericardium/embryology/metabolism
MH  - Quail/embryology
MH  - Reverse Transcriptase Polymerase Chain Reaction
MH  - Sequence Homology, Amino Acid
MH  - Time Factors
MH  - Tissue Distribution
EDAT- 1999/04/20 00:00
MHDA- 1999/04/20 00:01
CRDT- 1999/04/20 00:00
PHST- 1999/04/20 00:00 [pubmed]
PHST- 1999/04/20 00:01 [medline]
PHST- 1999/04/20 00:00 [entrez]
AID - S0012-1606(99)99246-1 [pii]
AID - 10.1006/dbio.1999.9246 [doi]
PST - ppublish
SO  - Dev Biol. 1999 May 1;209(1):159-71. doi: 10.1006/dbio.1999.9246.