PMID- 10207129
OWN - NLM
STAT- MEDLINE
DCOM- 19990630
LR  - 20091119
IS  - 0950-1991 (Print)
IS  - 0950-1991 (Linking)
VI  - 126
IP  - 10
DP  - 1999 May
TI  - Eph receptors and ephrins: effectors of morphogenesis.
PG  - 2033-44
AB  - Eph receptor tyrosine kinases and their ligands, the ephrins, appear to lie
      functionally at the interface between pattern formation and morphogenesis. We
      review the role of Eph and ephrin signalling in the formation of segmented
      structures, in the control of axon guidance and cell migration and in the
      development of the vasculature. We address the question of how the specificity of
      response is achieved and discuss the specificity of ephrin-Eph interactions and
      the significance of structural domains in Eph receptors.
FAU - Holder, N
AU  - Holder N
AD  - Department of Anatomy and Developmental Biology, University College, Gower
      Street, London, WC1 6BT, UK. Klein@embl-heidelberg.de
FAU - Klein, R
AU  - Klein R
LA  - eng
PT  - Journal Article
PT  - Review
PL  - England
TA  - Development
JT  - Development (Cambridge, England)
JID - 8701744
RN  - 0 (Ephrin-A1)
RN  - 0 (Proteins)
RN  - EC 2.7.10.1 (Receptor Protein-Tyrosine Kinases)
SB  - IM
MH  - Animals
MH  - Cell Transformation, Neoplastic
MH  - Ephrin-A1
MH  - Humans
MH  - Morphogenesis
MH  - Proteins/*metabolism
MH  - Receptor Protein-Tyrosine Kinases/*metabolism
MH  - *Signal Transduction
RF  - 104
EDAT- 1999/04/20 00:00
MHDA- 1999/04/20 00:01
CRDT- 1999/04/20 00:00
PHST- 1999/04/20 00:00 [pubmed]
PHST- 1999/04/20 00:01 [medline]
PHST- 1999/04/20 00:00 [entrez]
PST - ppublish
SO  - Development. 1999 May;126(10):2033-44.