PMID- 10198168
OWN - NLM
STAT- MEDLINE
DCOM- 19990506
LR  - 20090929
IS  - 0888-7543 (Print)
IS  - 0888-7543 (Linking)
VI  - 57
IP  - 2
DP  - 1999 Apr 15
TI  - cDNA characterization and chromosomal mapping of human golgi SNARE GS27 and GS28 
      to chromosome 17.
PG  - 285-8
AB  - Transport of proteins along the exocytotic pathway is primarily achieved by
      vesicular intermediates. Two proteins, Golgi SNAREs of 27 kDa, GS27, and of 28
      kDa, GS28 (HGMW-approved nomenclature GOSR2 and GOSR1, respectively), are
      important trafficking membrane proteins between the endoplasmic reticulum and the
      Golgi and between Golgi subcompartments. Here, we present the human GS27 and GS28
      cDNA sequences. They encode predicted proteins of 212 and 250 amino acids,
      respectively. Chromosomal mapping analyses reveal that human GS27 is located on
      chromosome 17q21 and GS28 on approximately 17q11. The chromosomal location of
      GS27 near a locus implicated in familial essential hypertension and its known
      function in trafficking indicate that it is a potential candidate gene for this
      disease.
CI  - Copyright 1999 Academic Press.
FAU - Bui, T D
AU  - Bui TD
AD  - Membrane Biology Laboratory, Institute of Molecular and Cell Biology, 30 Medical 
      Drive, Singapore, 117609, Singapore.
FAU - Levy, E R
AU  - Levy ER
FAU - Subramaniam, V N
AU  - Subramaniam VN
FAU - Lowe, S L
AU  - Lowe SL
FAU - Hong, W
AU  - Hong W
LA  - eng
SI  - GENBANK/AF007548
SI  - GENBANK/AF007549
GR  - Wellcome Trust/United Kingdom
PT  - Journal Article
PL  - United States
TA  - Genomics
JT  - Genomics
JID - 8800135
RN  - 0 (DNA, Complementary)
RN  - 0 (GOSR1 protein, human)
RN  - 0 (GOSR2 protein, human)
RN  - 0 (Gosr1 protein, mouse)
RN  - 0 (Gosr2 protein, rat)
RN  - 0 (Membrane Proteins)
RN  - 0 (Qb-SNARE Proteins)
SB  - IM
MH  - Chromosome Mapping
MH  - Chromosomes, Human, Pair 17/*genetics
MH  - DNA, Complementary/chemistry/*genetics
MH  - Humans
MH  - Hybrid Cells
MH  - In Situ Hybridization, Fluorescence
MH  - Membrane Proteins/*genetics
MH  - Molecular Sequence Data
MH  - Qb-SNARE Proteins
MH  - Sequence Analysis, DNA
EDAT- 1999/04/13 00:00
MHDA- 1999/04/13 00:01
CRDT- 1999/04/13 00:00
PHST- 1999/04/13 00:00 [pubmed]
PHST- 1999/04/13 00:01 [medline]
PHST- 1999/04/13 00:00 [entrez]
AID - S0888-7543(98)95649-X [pii]
AID - 10.1006/geno.1998.5649 [doi]
PST - ppublish
SO  - Genomics. 1999 Apr 15;57(2):285-8. doi: 10.1006/geno.1998.5649.