PMID- 10096065
OWN - NLM
STAT- MEDLINE
DCOM- 19990615
LR  - 20190909
IS  - 0925-4773 (Print)
IS  - 0925-4773 (Linking)
VI  - 80
IP  - 1
DP  - 1999 Jan
TI  - The RNA-binding protein gene, hermes, is expressed at high levels in the
      developing heart.
PG  - 77-86
AB  - In a screen for novel sequences expressed during embryonic heart development we
      have isolated a gene which encodes a putative RNA-binding protein. This protein
      is a member of one of the largest families of RNA-binding proteins, the RRM (RNA 
      Recognition Motif) family. The gene has been named hermes (for HEart, RRM
      Expressed Sequence). The hermes protein is 197-amino acids long and contains a
      single RRM domain. In situ hybridization analysis indicates that hermes is
      expressed at highest levels in the myocardium of the heart and to a lesser extent
      in the ganglion layer of the retina, the pronephros and epiphysis. Expression of 
      hermes in each of these tissues begins at approximately the time of
      differentiation and is maintained throughout development. Analysis of the RNA
      expression of the hermes orthologues from chicken and mouse reveals that, like
      Xenopus, the most prominent tissue of expression is the developing heart. The
      sequence and expression pattern of hermes suggests a role in post-transcriptional
      regulation of heart development.
FAU - Gerber, W V
AU  - Gerber WV
AD  - Institute for Cell and Molecular Biology, University of Texas at Austin 78712,
      USA.
FAU - Yatskievych, T A
AU  - Yatskievych TA
FAU - Antin, P B
AU  - Antin PB
FAU - Correia, K M
AU  - Correia KM
FAU - Conlon, R A
AU  - Conlon RA
FAU - Krieg, P A
AU  - Krieg PA
LA  - eng
SI  - GENBANK/AF107889
SI  - GENBANK/AF129933
SI  - GENBANK/AF148511
GR  - HL20220/HL/NHLBI NIH HHS/United States
GR  - HL52746/HL/NHLBI NIH HHS/United States
GR  - HL54133/HL/NHLBI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, U.S. Gov't, Non-P.H.S.
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - Ireland
TA  - Mech Dev
JT  - Mechanisms of development
JID - 9101218
RN  - 0 (RBPMS2 protein, Xenopus)
RN  - 0 (RNA-Binding Proteins)
RN  - 0 (Rbpms protein, mouse)
RN  - 0 (Xenopus Proteins)
SB  - IM
MH  - Amino Acid Sequence
MH  - Animals
MH  - Base Sequence
MH  - Blotting, Northern
MH  - Chick Embryo
MH  - Embryo, Mammalian/metabolism
MH  - Embryo, Nonmammalian/metabolism
MH  - Eye/metabolism
MH  - Gene Expression Regulation, Developmental
MH  - Gene Library
MH  - Heart/*embryology
MH  - Kidney/metabolism
MH  - Mice
MH  - Molecular Sequence Data
MH  - Multigene Family
MH  - Myocardium/metabolism
MH  - Protein Structure, Secondary
MH  - RNA-Binding Proteins/*metabolism
MH  - Sequence Homology, Amino Acid
MH  - Tissue Distribution
MH  - Xenopus/embryology
MH  - *Xenopus Proteins
EDAT- 1999/03/30 00:00
MHDA- 1999/03/30 00:01
CRDT- 1999/03/30 00:00
PHST- 1999/03/30 00:00 [pubmed]
PHST- 1999/03/30 00:01 [medline]
PHST- 1999/03/30 00:00 [entrez]
AID - S0925-4773(98)00195-6 [pii]
AID - 10.1016/s0925-4773(98)00195-6 [doi]
PST - ppublish
SO  - Mech Dev. 1999 Jan;80(1):77-86. doi: 10.1016/s0925-4773(98)00195-6.