PMID- 10095063
OWN - NLM
STAT- MEDLINE
DCOM- 19990506
LR  - 20190610
IS  - 0006-3002 (Print)
IS  - 0006-3002 (Linking)
VI  - 1444
IP  - 3
DP  - 1999 Mar 19
TI  - Structure and promoter region of the surface membrane protein HS9 gene expressed 
      on the thymic epithelial cells.
PG  - 407-11
AB  - The HS9 gene encoding a surface membrane protein is expressed in thymic
      epithelial cells. We have isolated the mouse HS9 gene and determined the sequence
      of all exons. The mouse HS9 gene is composed of 14 exons spanning approx. 31 kb. 
      Primer extension analysis identified two transcription initiation sites 33 bp and
      179 bp upstream from the ATG start codon. DNA sequence analysis of the
      5'-flanking region of the first exon revealed a number of consensus binding sites
      for known transcription factors such as GC box, Sp1, NFkappaB, gamma-IRE. Neither
      typical TATA nor CCAAT boxes were found in this region. These results and the
      analysis of the luciferase activity showed that transcription of the HS9 gene is 
      regulated at a TATA-less promoter.
FAU - Miyazawa, H
AU  - Miyazawa H
AD  - Department of Immunology, National Institute of Neuroscience, National Center of 
      Neurology and Psychiatry, Kodaira, Tokyo 187-8502, Japan. mia@ncnp.go.jp
FAU - Takeuchi, T
AU  - Takeuchi T
FAU - Yamamoto, H
AU  - Yamamoto H
LA  - eng
SI  - GENBANK/AB015172
PT  - Journal Article
PL  - Netherlands
TA  - Biochim Biophys Acta
JT  - Biochimica et biophysica acta
JID - 0217513
RN  - 0 (Membrane Proteins)
SB  - IM
MH  - Animals
MH  - Base Sequence
MH  - Cloning, Molecular
MH  - Epithelial Cells/metabolism
MH  - Exons
MH  - Genomic Library
MH  - Membrane Proteins/*genetics
MH  - Mice
MH  - Molecular Sequence Data
MH  - Promoter Regions, Genetic
MH  - Thymus Gland/*metabolism
MH  - Transcription, Genetic
EDAT- 1999/03/30 00:00
MHDA- 1999/03/30 00:01
CRDT- 1999/03/30 00:00
PHST- 1999/03/30 00:00 [pubmed]
PHST- 1999/03/30 00:01 [medline]
PHST- 1999/03/30 00:00 [entrez]
AID - S0167-4781(99)00013-5 [pii]
AID - 10.1016/s0167-4781(99)00013-5 [doi]
PST - ppublish
SO  - Biochim Biophys Acta. 1999 Mar 19;1444(3):407-11. doi:
      10.1016/s0167-4781(99)00013-5.