PMID- 10092526
OWN - NLM
STAT- MEDLINE
DCOM- 19990511
LR  - 20191210
IS  - 0006-291X (Print)
IS  - 0006-291X (Linking)
VI  - 257
IP  - 1
DP  - 1999 Apr 2
TI  - Multiple alternative transcripts of the human homologue of the mouse
      TRAD/R51H3/RAD51D gene, a member of the rec A/RAD51 gene family.
PG  - 156-62
AB  - Yeast RAD51, a homologue of Escherichia coli recA, plays a crucial role in
      mitotic and/or meiotic recombination and in the repair of double-strand DNA
      breaks. We have identified unique multiple alternative transcripts of a human
      TRAD/R51H3/RAD51D gene, a member of the recA/RAD51 gene family. One of the
      transcripts encoded a 328-amino-acid protein with 83.0% overall amino acid
      identity and 98. 2% similarity with the mouse TRAD gene and had two nucleotide
      binding consensus sequences, motif A and motif B, conserved among members of this
      family. Other transcripts encoded truncated proteins with a partial N-terminal
      region of the orthologue or short proteins lacking internal sequences which
      contain nucleotide binding motifs. Northern blot analysis revealed that multiple 
      transcripts of the human TRAD gene were expressed in various tissues and their
      distribution was not ubiquitous.
CI  - Copyright 1999 Academic Press.
FAU - Kawabata, M
AU  - Kawabata M
AD  - Department of Pharmacology, Okayama University Medical School, 2-5-1 Shikata-cho,
      Okayama, 700-8558, Japan.
FAU - Saeki, K
AU  - Saeki K
LA  - eng
SI  - GENBANK/AB013341
SI  - GENBANK/AB016223
SI  - GENBANK/AB016224
SI  - GENBANK/AB016225
SI  - GENBANK/AB018360
SI  - GENBANK/AB018361
SI  - GENBANK/AB018362
SI  - GENBANK/AB018363
SI  - GENBANK/AB020412
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Biochem Biophys Res Commun
JT  - Biochemical and biophysical research communications
JID - 0372516
RN  - 0 (DNA, Complementary)
RN  - 0 (DNA-Binding Proteins)
RN  - 0 (RAD51D protein, human)
RN  - 0 (RNA, Messenger)
RN  - 0 (Rad51d protein, mouse)
RN  - EC 2.7.7.- (RAD51 protein, human)
RN  - EC 2.7.7.- (Rad51 Recombinase)
RN  - EC 2.7.7.- (Rad51 protein, mouse)
SB  - IM
MH  - Alternative Splicing/*genetics
MH  - Amino Acid Sequence
MH  - Animals
MH  - Base Sequence
MH  - Blotting, Northern
MH  - Cloning, Molecular
MH  - DNA, Complementary/genetics
MH  - DNA-Binding Proteins/chemistry/*genetics
MH  - Exons/genetics
MH  - Genome, Human
MH  - Humans
MH  - Mice
MH  - Molecular Sequence Data
MH  - Open Reading Frames/genetics
MH  - RNA, Messenger/analysis/*genetics
MH  - Rad51 Recombinase
MH  - Reverse Transcriptase Polymerase Chain Reaction
MH  - Sequence Alignment
MH  - Sequence Analysis, DNA
MH  - Sequence Deletion
MH  - Sequence Homology, Amino Acid
EDAT- 1999/03/27 00:00
MHDA- 1999/03/27 00:01
CRDT- 1999/03/27 00:00
PHST- 1999/03/27 00:00 [pubmed]
PHST- 1999/03/27 00:01 [medline]
PHST- 1999/03/27 00:00 [entrez]
AID - S0006-291X(99)90413-8 [pii]
AID - 10.1006/bbrc.1999.0413 [doi]
PST - ppublish
SO  - Biochem Biophys Res Commun. 1999 Apr 2;257(1):156-62. doi:
      10.1006/bbrc.1999.0413.