PMID- 10081937
OWN - NLM
STAT- MEDLINE
DCOM- 19990506
LR  - 20190701
IS  - 0304-3940 (Print)
IS  - 0304-3940 (Linking)
VI  - 261
IP  - 1-2
DP  - 1999 Feb 12
TI  - Molecular cloning of the cone-rod homeobox gene (Crx) from the rat and its
      temporal expression pattern in the retina under a daily light-dark cycle.
PG  - 101-4
AB  - The primary structure of the cone-rod homeobox protein (CRX), a member of the
      OTX-like homeobox protein family, in the rat was deduced from the cDNA nucleotide
      sequence. The deduced protein consisted of 299 amino acid residues with motifs
      conserved in mammalian CRXs, and was 98% identical to mouse CRX. Northern blot
      analysis showed that Crx mRNA levels in the rat retina were constant under a
      daily light-dark cycle. These findings suggest that the expression mechanism of
      rat Crx in the retina was different from that in the pineal, where Crx mRNA
      exhibits a daily expression rhythm.
FAU - Sakamoto, K
AU  - Sakamoto K
AD  - National Institute of Bioscience and Human Technology, Agency of Industrial
      Science and Technology, MITI, Tsukuba, Ibaraki, Japan.
FAU - Oishi, K
AU  - Oishi K
FAU - Okada, T
AU  - Okada T
FAU - Onuma, Y
AU  - Onuma Y
FAU - Yokoyama, K
AU  - Yokoyama K
FAU - Sugimoto, K
AU  - Sugimoto K
FAU - Ishida, N
AU  - Ishida N
LA  - eng
SI  - GENBANK/AB021129
PT  - Journal Article
PL  - Ireland
TA  - Neurosci Lett
JT  - Neuroscience letters
JID - 7600130
RN  - 0 (DNA Primers)
RN  - 0 (DNA, Complementary)
RN  - 0 (Homeodomain Proteins)
RN  - 0 (RNA, Messenger)
RN  - 0 (Trans-Activators)
RN  - 0 (cone rod homeobox protein)
SB  - IM
MH  - Animals
MH  - Blotting, Northern
MH  - Circadian Rhythm/*physiology
MH  - Cloning, Molecular
MH  - DNA Primers
MH  - DNA, Complementary
MH  - Darkness
MH  - Gene Expression/physiology
MH  - Homeodomain Proteins/*genetics
MH  - Lighting
MH  - Male
MH  - Molecular Sequence Data
MH  - Pineal Gland/chemistry/physiology
MH  - RNA, Messenger/analysis
MH  - Rats
MH  - Rats, Wistar
MH  - Retinal Cone Photoreceptor Cells/chemistry/*physiology
MH  - Retinal Rod Photoreceptor Cells/chemistry/*physiology
MH  - Sequence Homology, Amino Acid
MH  - Trans-Activators/*genetics
EDAT- 1999/03/19 00:00
MHDA- 1999/03/19 00:01
CRDT- 1999/03/19 00:00
PHST- 1999/03/19 00:00 [pubmed]
PHST- 1999/03/19 00:01 [medline]
PHST- 1999/03/19 00:00 [entrez]
AID - S0304-3940(99)00008-7 [pii]
AID - 10.1016/s0304-3940(99)00008-7 [doi]
PST - ppublish
SO  - Neurosci Lett. 1999 Feb 12;261(1-2):101-4. doi: 10.1016/s0304-3940(99)00008-7.