PMID- 10080919
OWN - NLM
STAT- MEDLINE
DCOM- 19990419
LR  - 20161124
IS  - 0006-291X (Print)
IS  - 0006-291X (Linking)
VI  - 256
IP  - 3
DP  - 1999 Mar 24
TI  - Interaction of S-SCAM with neural plakophilin-related Armadillo-repeat
      protein/delta-catenin.
PG  - 456-61
AB  - Synaptic scaffolding molecule (S-SCAM) is a multiple PDZ domain-containing
      protein, which interacts with neuroligin, a cell adhesion molecule, and the NMDA 
      receptor. In this study, we searched for S-SCAM-interacting proteins and obtained
      a neuralplakophilin-related armadillo-repeat protein (NPRAP)/delta-catenin.
      NPRAP/delta-catenin bound to the last PDZ domain of S-SCAM via its
      carboxyl-terminus in three different cell-free assay systems, was
      coimmunoprecipitated with S-SCAM from rat crude synaptosomes, and was localized
      at the excitatory synapses in rat hippocampal neurons. NPRAP/delta-catenin may be
      implicated in the molecular organization of synaptic junctions through the
      interaction with S-SCAM.
CI  - Copyright 1999 Academic Press.
FAU - Ide, N
AU  - Ide N
AD  - Takai Biotimer Project, ERATO, Japan Science and Technology Corporation, c/o JCR 
      Pharmaceuticals Co. Ltd., Kobe, 651-2241, Japan.
FAU - Hata, Y
AU  - Hata Y
FAU - Deguchi, M
AU  - Deguchi M
FAU - Hirao, K
AU  - Hirao K
FAU - Yao, I
AU  - Yao I
FAU - Takai, Y
AU  - Takai Y
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Biochem Biophys Res Commun
JT  - Biochemical and biophysical research communications
JID - 0372516
RN  - 0 (Adaptor Proteins, Signal Transducing)
RN  - 0 (Armadillo Domain Proteins)
RN  - 0 (Carrier Proteins)
RN  - 0 (Ctnnd2 protein, rat)
RN  - 0 (Magi2 protein, rat)
RN  - 0 (Nerve Tissue Proteins)
RN  - 0 (Peptide Fragments)
RN  - 0 (Receptors, N-Methyl-D-Aspartate)
RN  - 0 (Recombinant Fusion Proteins)
RN  - EC 2.7.4.8 (Guanylate Kinases)
SB  - IM
MH  - Adaptor Proteins, Signal Transducing
MH  - Animals
MH  - Armadillo Domain Proteins
MH  - Binding Sites
MH  - Biosensing Techniques
MH  - COS Cells
MH  - Carrier Proteins/chemistry/genetics/*metabolism
MH  - Gene Library
MH  - Guanylate Kinases
MH  - Hippocampus/cytology/metabolism
MH  - Kinetics
MH  - Molecular Weight
MH  - Nerve Tissue Proteins/chemistry/genetics/*metabolism
MH  - Neurons/*metabolism
MH  - Peptide Fragments/chemical synthesis/metabolism
MH  - Precipitin Tests
MH  - Protein Binding
MH  - Rats
MH  - Receptors, N-Methyl-D-Aspartate/metabolism
MH  - Recombinant Fusion Proteins/biosynthesis/genetics/metabolism
MH  - Synaptosomes/metabolism
MH  - Transfection
MH  - Yeasts/genetics
EDAT- 1999/03/19 00:00
MHDA- 1999/03/19 00:01
CRDT- 1999/03/19 00:00
PHST- 1999/03/19 00:00 [pubmed]
PHST- 1999/03/19 00:01 [medline]
PHST- 1999/03/19 00:00 [entrez]
AID - S0006-291X(99)90364-9 [pii]
AID - 10.1006/bbrc.1999.0364 [doi]
PST - ppublish
SO  - Biochem Biophys Res Commun. 1999 Mar 24;256(3):456-61. doi:
      10.1006/bbrc.1999.0364.