PMID- 10072754
OWN - NLM
STAT- MEDLINE
DCOM- 19990413
LR  - 20190707
IS  - 0378-1119 (Print)
IS  - 0378-1119 (Linking)
VI  - 228
IP  - 1-2
DP  - 1999 Mar 4
TI  - Two forms of expression and genomic structure of the human heterogeneous nuclear 
      ribonucleoprotein D-like JKTBP gene (HNRPDL).
PG  - 13-22
AB  - The human DNA- and RNA-binding protein JKTBP is a member of a 2xRNA-binding
      domain (RBD)-glycine family of heterogeneous nuclear ribonucleoproteins that are 
      involved in mRNA biogenesis. Northern and Western blottings revealed that mRNAs
      of approx. 1.4 and 2.8kb and proteins of approx. 38 and 53kDa were present in
      HL-60 cells and various tissues. Cloning and characterization of a previously
      unknown cDNA for the 2.8kb mRNA indicated that the cDNA encodes a 420 amino acid 
      JKTBP polypeptide. Isolation and characterization of the genomic DNA showed that 
      the gene (HNRPDL) had nine exons and had two separate transcription start sites
      for the two transcripts. The features of the 5' flanking sequences of these sites
      showed that the gene is a housekeeping gene. Fluorescence in situ hybridization
      mapped the gene to 4q13-q21. From its gene organization, the JKTBP seems to be
      most closely related to hnRNP D/AUF1.
FAU - Kamei, D
AU  - Kamei D
AD  - Graduate School of Integrated Science, Yokohama City University, 22-2 Seto,
      Kanazawa-ku, Yokohama 236-0027, Japan.
FAU - Tsuchiya, N
AU  - Tsuchiya N
FAU - Yamazaki, M
AU  - Yamazaki M
FAU - Meguro, H
AU  - Meguro H
FAU - Yamada, M
AU  - Yamada M
LA  - eng
SI  - GENBANK/AB017018
SI  - GENBANK/AB017019
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Netherlands
TA  - Gene
JT  - Gene
JID - 7706761
RN  - 0 (DNA, Complementary)
RN  - 0 (HNRPDL protein, human)
RN  - 0 (RNA, Messenger)
RN  - 0 (Ribonucleoproteins)
RN  - 9007-49-2 (DNA)
SB  - IM
MH  - Amino Acid Sequence
MH  - Base Sequence
MH  - Chromosome Banding
MH  - Chromosome Mapping
MH  - Chromosomes, Human, Pair 4/genetics
MH  - Cloning, Molecular
MH  - DNA/chemistry/genetics
MH  - DNA, Complementary/chemistry/genetics
MH  - Exons
MH  - Gene Expression Regulation
MH  - Genes/*genetics
MH  - HL-60 Cells
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Introns
MH  - Molecular Sequence Data
MH  - RNA, Messenger/genetics/metabolism
MH  - Ribonucleoproteins/*genetics
MH  - Tissue Distribution
MH  - Transcription, Genetic
EDAT- 1999/03/12 00:00
MHDA- 1999/03/12 00:01
CRDT- 1999/03/12 00:00
PHST- 1999/03/12 00:00 [pubmed]
PHST- 1999/03/12 00:01 [medline]
PHST- 1999/03/12 00:00 [entrez]
AID - S0378-1119(99)00020-7 [pii]
AID - 10.1016/s0378-1119(99)00020-7 [doi]
PST - ppublish
SO  - Gene. 1999 Mar 4;228(1-2):13-22. doi: 10.1016/s0378-1119(99)00020-7.