PMID- 10072596
OWN - NLM
STAT- MEDLINE
DCOM- 19990330
LR  - 20171101
IS  - 0301-0171 (Print)
IS  - 0301-0171 (Linking)
VI  - 83
IP  - 3-4
DP  - 1998
TI  - Molecular cloning, mapping, and characterization of two novel human genes, ORCTL3
      and ORCTL4, bearing homology to organic-cation transporters.
PG  - 251-5
AB  - Through a large-scale sequencing of genomic DNA at 3p22-->p21.3, we have isolated
      two human genes (ORCTL3 alias OCTL1 and ORCTL4 alias OCTL2) encoding novel
      members of the family of organic-cation transporter molecules. The predicted
      proteins revealed the highest similarities to recently- isolated organic-cation
      transporter proteins, rat OCT-1r, rat NLT and mouse NKT. The transcripts of both 
      genes were expressed ubiquitously in various human tissues, but some
      tissue-specific transcripts were also observed in kidney, testis, or skeletal
      muscle. The two genes are clustered within a 52-kb region of genomic DNA and
      ORCTL4 lies about 27 kb telomeric to ORCTL3 in the genomic DNA sequence in a
      tail-to-head orientation.
FAU - Nishiwaki, T
AU  - Nishiwaki T
AD  - Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical
      Science, The University of Tokyo, Tokyo, Japan.
FAU - Daigo, Y
AU  - Daigo Y
FAU - Tamari, M
AU  - Tamari M
FAU - Fujii, Y
AU  - Fujii Y
FAU - Nakamura, Y
AU  - Nakamura Y
LA  - eng
SI  - GENBANK/AB010438
SI  - GENBANK/AB011082
SI  - GENBANK/AB026898
SI  - GENBANK/AB026899
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Switzerland
TA  - Cytogenet Cell Genet
JT  - Cytogenetics and cell genetics
JID - 0367735
RN  - 0 (Carrier Proteins)
RN  - 0 (DNA, Complementary)
RN  - 0 (Organic Anion Transporters)
RN  - 0 (SLC22A13 protein, human)
RN  - 63231-63-0 (RNA)
RN  - 9007-49-2 (DNA)
SB  - IM
MH  - Amino Acid Sequence
MH  - Base Sequence
MH  - Blotting, Northern
MH  - Carrier Proteins/*genetics
MH  - Chromosome Mapping
MH  - Chromosomes, Human, Pair 3/genetics
MH  - Cloning, Molecular
MH  - DNA/chemistry/genetics
MH  - DNA, Complementary/chemistry/genetics/isolation & purification
MH  - Exons
MH  - Genes/*genetics
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Introns
MH  - Molecular Sequence Data
MH  - Organic Anion Transporters/*genetics
MH  - RNA/genetics/metabolism
MH  - Sequence Alignment
MH  - Sequence Analysis, DNA
MH  - Sequence Homology, Amino Acid
MH  - Tissue Distribution
MH  - Transcription, Genetic
EDAT- 1999/03/11 03:01
MHDA- 2000/08/16 11:00
CRDT- 1999/03/11 03:01
PHST- 1999/03/11 03:01 [pubmed]
PHST- 2000/08/16 11:00 [medline]
PHST- 1999/03/11 03:01 [entrez]
AID - 15197 [pii]
AID - 10.1159/000015197 [doi]
PST - ppublish
SO  - Cytogenet Cell Genet. 1998;83(3-4):251-5. doi: 10.1159/000015197.