PMID- 10051408
OWN - NLM
STAT- MEDLINE
DCOM- 19990422
LR  - 20061115
IS  - 0888-7543 (Print)
IS  - 0888-7543 (Linking)
VI  - 56
IP  - 2
DP  - 1999 Mar 1
TI  - Genomic structure and chromosomal localization of TCEAL1, a human gene encoding
      the nuclear phosphoprotein p21/SIIR.
PG  - 217-20
AB  - Human p21/SIIR is a novel Ser/Arg/Pro-rich nuclear phosphoprotein that is 48%
      similar to transcription factor SII and modulates transcription in a promoter
      context-dependent fashion. We have obtained the complete sequence of TCEAL1, the 
      gene that codes for p21/SIIR. This gene consists of three exons and two introns
      with the entire coding sequence in exon III. Tissue-specific expression patterns 
      of TCEAL1 by Northern blot analysis showed the presence of an approximately
      1.2-kb transcript in all normal human tissues examined, and heart and skeletal
      muscle contained an additional transcript of approximately 7 kb. Expression was
      lowest in hematopoietic cells of both normal and tumor origin. TCEAL1 was mapped 
      to human chromosome Xq22.1 by fluorescence in situ hybridization.
CI  - Copyright 1999 Academic Press.
FAU - Pillutla, R C
AU  - Pillutla RC
AD  - Center for Advanced Biotechnology and Medicine, 679 Hoes Lane, Piscataway, New
      Jersey 08854-5638, USA.
FAU - Shimamoto, A
AU  - Shimamoto A
FAU - Furuichi, Y
AU  - Furuichi Y
FAU - Shatkin, A J
AU  - Shatkin AJ
LA  - eng
SI  - GENBANK/AF095906
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Genomics
JT  - Genomics
JID - 8800135
RN  - 0 (DNA-Binding Proteins)
RN  - 0 (Nuclear Proteins)
RN  - 0 (Phosphoproteins)
RN  - 0 (RNA, Messenger)
RN  - 0 (TCEAL1 protein, human)
RN  - 0 (Transcription Factors)
RN  - 9007-49-2 (DNA)
SB  - IM
MH  - Animals
MH  - Chickens
MH  - Chromosome Banding
MH  - Chromosome Mapping
MH  - DNA/chemistry/genetics
MH  - DNA-Binding Proteins/*genetics
MH  - Exons
MH  - Female
MH  - Genes/*genetics
MH  - HeLa Cells
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Introns
MH  - Male
MH  - Mice
MH  - Molecular Sequence Data
MH  - Nuclear Proteins/*genetics
MH  - Phosphoproteins/*genetics
MH  - RNA, Messenger/genetics/metabolism
MH  - Sequence Analysis, DNA
MH  - Tissue Distribution
MH  - Transcription Factors/*genetics
MH  - Tumor Cells, Cultured
MH  - X Chromosome/*genetics
EDAT- 1999/03/03 00:00
MHDA- 1999/03/03 00:01
CRDT- 1999/03/03 00:00
PHST- 1999/03/03 00:00 [pubmed]
PHST- 1999/03/03 00:01 [medline]
PHST- 1999/03/03 00:00 [entrez]
AID - S0888-7543(98)95705-6 [pii]
AID - 10.1006/geno.1998.5705 [doi]
PST - ppublish
SO  - Genomics. 1999 Mar 1;56(2):217-20. doi: 10.1006/geno.1998.5705.