PMID- 10049777
OWN - NLM
STAT- MEDLINE
DCOM- 19990401
LR  - 20061115
IS  - 0006-291X (Print)
IS  - 0006-291X (Linking)
VI  - 255
IP  - 3
DP  - 1999 Feb 24
TI  - Cloning and characterization of a cDNA encoding a novel fibroblast growth factor 
      preferentially expressed in human heart.
PG  - 717-21
AB  - A novel human fibroblast growth factor (hFGF), which shows 75% sequence homology 
      with fibroblast growth factor-9, was isolated in random sequencing of a human
      heart cDNA library. The full-length sequence is 928 bp, the encoded protein is
      composed of 168 amino acid residues, and its pI value and molecular weight were
      estimated to be 8.13 and 19.1 kDa, respectively. RT-PCR using Marathon human
      heart cDNA shows that the coding region is approximately 507 bp. Southern
      hybridization showed a single band which indicates that this is a single copy
      gene. Northern hybridization done on a human multiple tissues blot showed that
      the gene is preferentially expressed in human heart, very weakly detectable in
      human brain and not detectable in 18 other different human tissues.
CI  - Copyright 1999 Academic Press.
FAU - Kok, L D
AU  - Kok LD
AD  - Department of Biochemistry, Chinese University of Hong Kong, Shatin, New
      Territories, Hong Kong, China.
FAU - Tsui, S K
AU  - Tsui SK
FAU - Waye, M
AU  - Waye M
FAU - Liew, C C
AU  - Liew CC
FAU - Lee, C Y
AU  - Lee CY
FAU - Fung, K P
AU  - Fung KP
LA  - eng
SI  - GENBANK/U76381
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Biochem Biophys Res Commun
JT  - Biochemical and biophysical research communications
JID - 0372516
RN  - 0 (FGF9 protein, human)
RN  - 0 (Fibroblast Growth Factor 9)
RN  - 0 (Growth Substances)
RN  - 0 (RNA, Messenger)
RN  - 62031-54-3 (Fibroblast Growth Factors)
SB  - IM
MH  - Amino Acid Sequence
MH  - Base Sequence
MH  - Cloning, Molecular
MH  - Fibroblast Growth Factor 9
MH  - Fibroblast Growth Factors/chemistry/*genetics
MH  - Gene Expression/genetics
MH  - Growth Substances/chemistry
MH  - Humans
MH  - Isoelectric Point
MH  - Molecular Sequence Data
MH  - Myocardium/*metabolism
MH  - RNA, Messenger/metabolism
MH  - Sequence Analysis, DNA
MH  - Sequence Homology, Amino Acid
EDAT- 1999/03/02 00:00
MHDA- 1999/03/02 00:01
CRDT- 1999/03/02 00:00
PHST- 1999/03/02 00:00 [pubmed]
PHST- 1999/03/02 00:01 [medline]
PHST- 1999/03/02 00:00 [entrez]
AID - S0006-291X(99)90178-X [pii]
AID - 10.1006/bbrc.1999.0178 [doi]
PST - ppublish
SO  - Biochem Biophys Res Commun. 1999 Feb 24;255(3):717-21. doi:
      10.1006/bbrc.1999.0178.