PMID- 10049694
OWN - NLM
STAT- MEDLINE
DCOM- 19990311
LR  - 20111117
IS  - 0006-291X (Print)
IS  - 0006-291X (Linking)
VI  - 255
IP  - 2
DP  - 1999 Feb 16
TI  - The fourth member of the FHL family of LIM proteins is expressed exclusively in
      the testis.
PG  - 251-5
AB  - We have determined the sequence of a novel LIM protein, termed FHL4. It was found
      to contain the defining secondary structural arrangement of the FHL (formerly
      SLIM) family of LIM proteins. This sequence was assembled using EST sequences
      deposited on the dbEST database and from sequencing of PCR fragments, all of
      which were derived from murine testis cDNA. Northern analysis of a wide range of 
      murine tissues demonstrated that the expression of FHL4 mRNA was restricted to
      the testis. Using in situ hybridisation, FHL4 mRNA was found to be associated
      with the seminiferous epithelium and not with the interstitial tissue surrounding
      the seminiferous tubules. It is suggested that mFHL4 is associated with the
      process of spermatogenesis.
CI  - Copyright 1999 Academic Press.
FAU - Morgan, M J
AU  - Morgan MJ
AD  - Department of Orthodontics, Eastman Dental Institute for Oral Health Care
      Sciences, University of London, United Kingdom. mmorgan@eastman.ucl.ac.uk
FAU - Madgwick, A J
AU  - Madgwick AJ
LA  - eng
SI  - GENBANK/AF053486
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Biochem Biophys Res Commun
JT  - Biochemical and biophysical research communications
JID - 0372516
RN  - 0 (FHL4 protein, mouse)
RN  - 0 (Fhl2 protein, mouse)
RN  - 0 (Homeodomain Proteins)
RN  - 0 (LIM Domain Proteins)
RN  - 0 (LIM-Homeodomain Proteins)
RN  - 0 (Muscle Proteins)
RN  - 0 (Nuclear Proteins)
RN  - 0 (Proteins)
RN  - 0 (Proto-Oncogene Proteins c-myc)
RN  - 0 (RNA, Messenger)
RN  - 0 (Transcription Factors)
RN  - 130704-09-5 (cysteine-rich protein, mammalian)
SB  - IM
MH  - Amino Acid Sequence
MH  - Animals
MH  - Expressed Sequence Tags
MH  - Female
MH  - Homeodomain Proteins/*biosynthesis/chemistry/genetics
MH  - In Situ Hybridization
MH  - LIM Domain Proteins
MH  - LIM-Homeodomain Proteins
MH  - Male
MH  - Mice
MH  - Molecular Sequence Data
MH  - *Muscle Proteins
MH  - *Nuclear Proteins
MH  - *Proteins
MH  - Proto-Oncogene Proteins c-myc/*biosynthesis
MH  - RNA, Messenger/biosynthesis
MH  - Sequence Homology, Amino Acid
MH  - Testis/*metabolism
MH  - *Transcription Factors
MH  - Zinc Fingers/genetics
EDAT- 1999/03/02 00:00
MHDA- 1999/03/02 00:01
CRDT- 1999/03/02 00:00
PHST- 1999/03/02 00:00 [pubmed]
PHST- 1999/03/02 00:01 [medline]
PHST- 1999/03/02 00:00 [entrez]
AID - S0006-291X(99)90180-8 [pii]
AID - 10.1006/bbrc.1999.0180 [doi]
PST - ppublish
SO  - Biochem Biophys Res Commun. 1999 Feb 16;255(2):251-5. doi:
      10.1006/bbrc.1999.0180.