PMID- 10049693
OWN - NLM
STAT- MEDLINE
DCOM- 19990311
LR  - 20111117
IS  - 0006-291X (Print)
IS  - 0006-291X (Linking)
VI  - 255
IP  - 2
DP  - 1999 Feb 16
TI  - The LIM proteins FHL1 and FHL3 are expressed differently in skeletal muscle.
PG  - 245-50
AB  - We have determined the complete mRNA sequence of FHL3 (formerly SLIM2). We have
      confirmed that it is a member of the family of LIM proteins that share a similar 
      secondary protein structure, renamed as Four-and-a-Half-LIM domain (or FHL)
      proteins in accordance with this structure. The "half-LIM" domain is a single
      zinc finger domain that may represent a subfamily of LIM domains and defines this
      particular family of LIM proteins. The distribution of FHL mRNA expression within
      a variety of murine tissues is complex. Both FHL1 and FHL3 were expressed in a
      number of skeletal muscles while FHL2 was expressed at high levels in cardiac
      muscle. Localisation of FHL3 to human chromosome 1 placed this gene in the
      proximity of, but not overlapping with, alleles associated with muscle diseases. 
      FHL1 and FHL3 mRNAs were reciprocally expressed in the murine C2C12 skeletal
      muscle cell line and this suggested that the pattern of expression was linked to 
      key events in myogenesis.
CI  - Copyright 1999 Academic Press.
FAU - Morgan, M J
AU  - Morgan MJ
AD  - Department of Orthodontics, Eastman Dental Institute for Oral Health Care
      Sciences, University of London, United Kingdom. mmorgan@eastman.ucl.ac.uk
FAU - Madgwick, A J
AU  - Madgwick AJ
LA  - eng
SI  - GENBANK/AF053486
SI  - GENBANK/AF134772
SI  - GENBANK/AF134774
SI  - GENBANK/U60115
SI  - GENBANK/U60116
SI  - GENBANK/U77039
SI  - GENBANK/U77040
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Biochem Biophys Res Commun
JT  - Biochemical and biophysical research communications
JID - 0372516
RN  - 0 (FHL3 protein, human)
RN  - 0 (Fhl3 protein, mouse)
RN  - 0 (Homeodomain Proteins)
RN  - 0 (Intracellular Signaling Peptides and Proteins)
RN  - 0 (LIM Domain Proteins)
RN  - 0 (Muscle Proteins)
RN  - 0 (Nuclear Proteins)
RN  - 0 (Proteins)
RN  - 0 (Proto-Oncogene Proteins c-myc)
RN  - 130704-09-5 (cysteine-rich protein, mammalian)
SB  - IM
MH  - Amino Acid Sequence
MH  - Animals
MH  - Blotting, Northern
MH  - Cell Line
MH  - Chromosome Mapping
MH  - Chromosomes, Human, Pair 1
MH  - Female
MH  - Homeodomain Proteins/*biosynthesis/chemistry/genetics
MH  - Humans
MH  - Intracellular Signaling Peptides and Proteins
MH  - LIM Domain Proteins
MH  - Male
MH  - Mice
MH  - Molecular Sequence Data
MH  - Muscle Proteins/*biosynthesis/chemistry/genetics
MH  - Muscle, Skeletal/*metabolism
MH  - *Nuclear Proteins
MH  - *Proteins
MH  - Proto-Oncogene Proteins c-myc/*biosynthesis/genetics
MH  - Sequence Analysis
MH  - Sequence Homology, Amino Acid
MH  - Zebrafish
MH  - *Zinc Fingers/genetics
EDAT- 1999/03/02 00:00
MHDA- 1999/03/02 00:01
CRDT- 1999/03/02 00:00
PHST- 1999/03/02 00:00 [pubmed]
PHST- 1999/03/02 00:01 [medline]
PHST- 1999/03/02 00:00 [entrez]
AID - S0006-291X(99)90179-1 [pii]
AID - 10.1006/bbrc.1999.0179 [doi]
PST - ppublish
SO  - Biochem Biophys Res Commun. 1999 Feb 16;255(2):245-50. doi:
      10.1006/bbrc.1999.0179.