PMID- 10049592
OWN - NLM
STAT- MEDLINE
DCOM- 19990524
LR  - 20111117
IS  - 0888-7543 (Print)
IS  - 0888-7543 (Linking)
VI  - 55
IP  - 3
DP  - 1999 Feb 1
TI  - A physical map of the mouse shaker-2 region contains many of the genes commonly
      deleted in Smith-Magenis syndrome (del17p11.2p11.2).
PG  - 348-52
AB  - We report the construction of a physical map of the region of mouse chromosome 11
      that encompasses shaker-2 (sh2), a model for the human nonsyndromic deafness
      DFNB3. DFNB3 maps within the common deletion region of Smith-Magenis syndrome
      (SMS), del(17)(p11.2p11.2). Eleven of the genes mapping within the SMS common
      deletion region have murine homologs on the sh2 physical map. The gene order in
      this region is not perfectly conserved between mouse and human, a finding to be
      considered as we engineer a mouse model of Smith-Magenis syndrome.
FAU - Probst, F J
AU  - Probst FJ
AD  - Department of Human Genetics, University of Michigan, Ann Arbor 48109, USA.
FAU - Chen, K S
AU  - Chen KS
FAU - Zhao, Q
AU  - Zhao Q
FAU - Wang, A
AU  - Wang A
FAU - Friedman, T B
AU  - Friedman TB
FAU - Lupski, J R
AU  - Lupski JR
FAU - Camper, S A
AU  - Camper SA
LA  - eng
SI  - GENBANK/AF081119
SI  - GENBANK/AF081120
SI  - GENBANK/AF081121
SI  - GENBANK/AF081122
SI  - GENBANK/AF081123
SI  - GENBANK/AF081124
GR  - R01 HD30428/HD/NICHD NIH HHS/United States
GR  - Z01 DC 00035/DC/NIDCD NIH HHS/United States
GR  - Z01 DC 00038/DC/NIDCD NIH HHS/United States
GR  - etc.
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, Non-P.H.S.
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Genomics
JT  - Genomics
JID - 8800135
RN  - 0 (DNA Primers)
RN  - 0 (MYO15A protein, human)
RN  - 0 (Myo15 protein, mouse)
RN  - EC 3.6.4.1 (Myosins)
SB  - IM
MH  - Abnormalities, Multiple/*genetics
MH  - Animals
MH  - Chromosomes, Artificial, Yeast
MH  - Chromosomes, Human, Pair 17/*genetics
MH  - DNA Primers
MH  - Disease Models, Animal
MH  - Gene Deletion
MH  - Humans
MH  - Intellectual Disability/genetics
MH  - Mice
MH  - Models, Genetic
MH  - Molecular Sequence Data
MH  - Myosins/*genetics
MH  - Physical Chromosome Mapping
MH  - Sequence Tagged Sites
MH  - Syndrome
EDAT- 1999/03/02 00:00
MHDA- 1999/03/02 00:01
CRDT- 1999/03/02 00:00
PHST- 1999/03/02 00:00 [pubmed]
PHST- 1999/03/02 00:01 [medline]
PHST- 1999/03/02 00:00 [entrez]
AID - S0888-7543(98)95669-5 [pii]
AID - 10.1006/geno.1998.5669 [doi]
PST - ppublish
SO  - Genomics. 1999 Feb 1;55(3):348-52. doi: 10.1006/geno.1998.5669.