Identification and Provenance fields =================================================================================================== Object ID: 0001 Type ID: 1 Name: Human [taxID:9606] Proteome Title: - Version: 1.1 Created: Jan 5, 2017 09:40:17 Created by: Rahi Navelkar (rsn13@gwu.edu) Modified: -Jan 12, 2018 Modified by: -Lama Elzohary(lama@gwu.edu) Digital Signature: D43F2404CA13E22594E5C8B04D3BBB81 Verification status: in_progress Publication_status": Draft Authors: Maria Martin (martin@ebi.ac.uk); Leyla Garcia (ljgarcia@ebi.ac.uk) Usability domain: Collect all canonical proteins and their isoforms to get a comprehensive list of all Human [taxID: 9606] proteins. Keywords: complete proteome [UniProt KW-0181] Description =================================================================================================== This table was generated as part of the supporting information to accompany submission of the manuscript titled "Loss and Gain of N-linked Glycosylation Sequons due to Single-nucleotide Variation in Cancer." This manuscript describes the workflow for identifying all possible N-linked glycosylation (NLG) sequons described in the given table. This table contains 59,341 NLGs identified by one of three methods: high-confidence NLGs (previously reported in databases with accompanying validated evidence or manual assertion tags), NLGs predicted by NetNGlyc (http://www.cbs.dtu.dk/services/NetNGlyc/), and custom scripts to identify all NXS/T (X!=P) sequons by string search. Table Headers ==================================================================================================== Column Header Description ------------- ------------ UniProtKB_AC UniProtKB/Swiss-Prot Accession Gene_Symbol Gene Symbol Protein_name Protein name as reported by UniProt Sequence_Length Length of protein in amino acids Signal_Peptide_Existence Describes if a signal peptide is reported for that protein in UniProt Signal_Peptide_Position Reports the annotated signal peptide position if Signal_Peptide_Existence is "Y" Cellular_component Relevant cellular component keyword(s) associated with the protein in UniProt Motif_position Position of the "N" in the identified NXS/T sequon Subsequence Four-residue sequence about the NXS/T sequon beginning with the "N" Methods Identification method(s) used to find a given sequon in a given protein Domain Domain mapping to the position, if reported Secondary_Structure Secondary structure mapping to the position, if reported NetNGlyc_Prediction Likelihood of actual glycosylation at the sequon, as reported by NetNGly