doc_id	sent_index	relation_id	relation	trigger	trigger_offset	arg_num	arg_base_np	arg_protein	arg_domain	arg_site	arg_sugar	PSource	SiteSource	NProtein	NID	SiteName	sent_text
29133098	3	17	gly	homogeneity	568:578	arg1	MCP	MCP				OGER		MCP	P40121		The molar mass (Mw), degree of esterification (DE), monosaccharide composition, 13C NMR spectra, homogeneity, morphology (SEM) and rheological behavior of both native and modified citrus pectins (MCP) were investigated.
26102015	1	20	gly	glycoprotein	280:291	arg1	GP	GP				Cterm		(GP) IIb			The results of randomized trials and observational studies make a strong argument for the use of bivalirudin rather than heparin plus systematic glycoprotein (GP) IIb/IIIa inhibitors for the great majority of patients undergoing percutaneous coronary interventions (PCI).
27102717	12	61	gly	C	1468:1468	arg1	non-milk sugar intakes	vitamin C, 53			non-milk sugar intakes	Cterm		vitamin C, 53			F&V contributed 50 % of vitamin C, 53 % of carotene, 34 % of dietary fibre and 42 % of non-milk sugar intakes from the total diet.
26296369	5	67	gly	CD69	1094:1097	arg1	the N-glycan composition	CD69			the N-glycan composition	OGER		CD69	Q07108		In agreement, the glycomics analysis determines the glycosylation site and the N-glycan composition of CD69, and terminal removal of sialic acid from that N-linked glycans reverses the generation of forkhead box P3-positive Treg cells (23.21%; P < 0.05).
26296369	5	84	gly	glycosylation	1043:1055	arg1	CD69	CD69				OGER		CD69	Q07108		In agreement, the glycomics analysis determines the glycosylation site and the N-glycan composition of CD69, and terminal removal of sialic acid from that N-linked glycans reverses the generation of forkhead box P3-positive Treg cells (23.21%; P < 0.05).
28552410	2	51	gly	β-1,3-glucan	458:469	arg1	cell wall core carbohydrates	-1,3			cell wall core carbohydrates	PUBTATOR		-1,3	97440		In a mouse model of fungal conidia aspiration, decreased relative levels of cell wall core carbohydrates β-1,3-glucan to chitin in A. fumigatus isolates and mutant strains were correlated with increased airway eosinophil recruitment.
27885831	3	8	gly	ECM	507:509	arg1	the glycosaminoglycan component	ECM			the glycosaminoglycan component	OGER		ECM	Q13201		Here, a polyanionic functionalized alginate is used to mimic the glycosaminoglycan component of the native ECM.
28396675	3	56	gly	1,3	624:626	arg1	plant-specific glycans	(1,3)-fucosyltransferase			plant-specific glycans	PUBTATOR		(1,3)-fucosyltransferase	107767349		Two enzymes are responsible for the addition of plant-specific glycans: β(1,2)-xylosyltransferase (XylT) and α(1,3)-fucosyltransferase (FucT).
28396675	3	94	gly	-xylosyltransferase	591:609	arg1	β(1,2)-xylosyltransferase (XylT) and α(1,3)-fucosyltransferase	(1,2)-xylosyltransferase			β(1,2)-xylosyltransferase (XylT) and α(1,3)-fucosyltransferase	PUBTATOR		(1,2)-xylosyltransferase	107760241		Two enzymes are responsible for the addition of plant-specific glycans: β(1,2)-xylosyltransferase (XylT) and α(1,3)-fucosyltransferase (FucT).
28396675	3	94	gly	-xylosyltransferase	591:609	arg1	FucT	(1,2)-xylosyltransferase			FucT	PUBTATOR		(1,2)-xylosyltransferase	107760241		Two enzymes are responsible for the addition of plant-specific glycans: β(1,2)-xylosyltransferase (XylT) and α(1,3)-fucosyltransferase (FucT).
28396675	3	94	gly	-xylosyltransferase	591:609	arg1	plant-specific glycans	(1,2)-xylosyltransferase			plant-specific glycans	PUBTATOR		(1,2)-xylosyltransferase	107760241		Two enzymes are responsible for the addition of plant-specific glycans: β(1,2)-xylosyltransferase (XylT) and α(1,3)-fucosyltransferase (FucT).
28396675	3	100	gly	1,2	587:589	arg1	β(1,2)-xylosyltransferase (XylT) and α(1,3)-fucosyltransferase	(1,2)-xylosyltransferase			β(1,2)-xylosyltransferase (XylT) and α(1,3)-fucosyltransferase	PUBTATOR		(1,2)-xylosyltransferase	107760241		Two enzymes are responsible for the addition of plant-specific glycans: β(1,2)-xylosyltransferase (XylT) and α(1,3)-fucosyltransferase (FucT).
28396675	3	100	gly	1,2	587:589	arg1	FucT	(1,2)-xylosyltransferase			FucT	PUBTATOR		(1,2)-xylosyltransferase	107760241		Two enzymes are responsible for the addition of plant-specific glycans: β(1,2)-xylosyltransferase (XylT) and α(1,3)-fucosyltransferase (FucT).
28396675	3	100	gly	1,2	587:589	arg1	plant-specific glycans	(1,2)-xylosyltransferase			plant-specific glycans	PUBTATOR		(1,2)-xylosyltransferase	107760241		Two enzymes are responsible for the addition of plant-specific glycans: β(1,2)-xylosyltransferase (XylT) and α(1,3)-fucosyltransferase (FucT).
26423601	2	69	gly	ECM	313:315	arg1	The proteoglycan composition	ECM			The proteoglycan composition	OGER		ECM	Q13201		The proteoglycan composition of the leiomyoma ECM is thought to affect pathophysiology of the disease.
28287093	8	72	gly	glycoprotein	1501:1512	arg1	HDL glycoprotein composition	HDL glycoprotein composition				OGER		HDL glycoprotein	Q9UNE0		Our results demonstrate that HDL glycoprotein composition, including the site-specific glycosylation, differentiate between clinical groups, correlate with HDL's immunomodulatory capacity, and may be predictive of HDL's ability to protect from infection.
26957414	9	64	gly	glycoproteins	1166:1178	arg1	porcine thyroglobulin	porcine thyroglobulin				OGER		thyroglobulin	P01266		ISF was employed to study the glycosylation sites of three model glycoproteins, including fetuin, α1-acid glycoprotein and porcine thyroglobulin.
26957414	9	112	gly	glycosylation	1131:1143	arg1	porcine thyroglobulin	porcine thyroglobulin				OGER		thyroglobulin	P01266		ISF was employed to study the glycosylation sites of three model glycoproteins, including fetuin, α1-acid glycoprotein and porcine thyroglobulin.
25817687	6	53	gly	SGP-2	1230:1234	arg1	polysaccharides	SGP-2			polysaccharides	PUBTATOR		SGP-2	P10909		These findings strongly suggested polysaccharides were also the anti-inflammatory active ingredient for S. glabra, and the potential of SGP-1 and SGP-2 as the anti-inflammatory agents.
25817687	6	63	gly	SGP-1	1220:1224	arg1	polysaccharides	SGP-1			polysaccharides	PUBTATOR		SGP-1	109941		These findings strongly suggested polysaccharides were also the anti-inflammatory active ingredient for S. glabra, and the potential of SGP-1 and SGP-2 as the anti-inflammatory agents.
28987883	8	65	gly	asialoglycoprotein	1269:1286	arg1	the asialoglycoprotein receptor	the asialoglycoprotein receptor				PUBTATOR		asialoglycoprotein receptor	432		Bioconjugation of N-acetylgalactosamine (GalNAc), a ligand to the asialoglycoprotein receptor (ASGPR) overexpressed on hepatocytes, was validated by XPS analysis and cell uptake by receptor-mediated mechanism.
25273383	2	55	gly	Sp7	395:397	arg1	the complete lipopolysaccharide	Sp7			the complete lipopolysaccharide	OGER		Sp7	Q8TDD2		To study changes in the electro-optical (EO) properties of the suspensions, we used antibodies generated to the complete lipopolysaccharide of A. brasilense type strain Sp7 and also antibodies to the smooth and rough O polysaccharides of Sp7.
25273383	2	19	gly	Sp7	464:466	arg1	the smooth and rough O polysaccharides	Sp7			the smooth and rough O polysaccharides	OGER		Sp7	Q8TDD2		To study changes in the electro-optical (EO) properties of the suspensions, we used antibodies generated to the complete lipopolysaccharide of A. brasilense type strain Sp7 and also antibodies to the smooth and rough O polysaccharides of Sp7.
24376168	7	63	gly	released	1290:1297	arg1	SSB AND sugars	SSB			sugars	OGER		SSB	P05455		Results from this study can be applied to large scale biorefineries using sugars released from SSB for producing various biofuels.
28747495	4	56	gly	polypeptide	809:819	arg1	GalNAcT1	polypeptide N-acetylgalactosaminyltransferase 1			GalNAcT1	PUBTATOR		polypeptide N-acetylgalactosaminyltransferase 1	2589		When HIV virions were generated in cells overexpressing polypeptide N-acetylgalactosaminyltransferase 1 (GalNAcT1), viral infectivity was increased 2.5-fold compared to that of virus produced in wild-type HEK293T cells; infectivity was increased 8-fold when the Thr499Ser mutant was used.
29326706	2	31	gly	TLR2	265:268	arg1	N-glycans	TLR2			N-glycans	PUBTATOR		TLR2	7097		The plant lectin ArtinM, for example, interacts with N-glycans of TLR2, whereas other lectins of microbial origin interact with TLR2 and TLR4.
25762620	8	41	gly	structures	1079:1088	arg1	Mucin (MUC) 1	MUC) 1			structures	OGER		MUC) 1	P15941		Furthermore, C1GALT1 modulates O-glycan structures on Mucin (MUC) 1 and promotes MUC1-C/β-catenin signaling in breast cancer cells.
24269369	6	16	part_of	possess	882:888	arg1	VaH4-A AND the Cys174	VaH4		Cys174		Cterm	AminoAcid	VaH4		Cys174	However, neither VaH4-A nor VaH4-B possess the Cys174 involved in the inter-subunit disulphide bond of P-III SVMPs.
28287093	1	19	gly	glycoprotein	229:240	arg1	HDL glycoprotein composition	HDL glycoprotein composition				OGER		HDL glycoprotein	Q9UNE0		The goal of this pilot study was to determine whether HDL glycoprotein composition affects HDL's immunomodulatory function.
28549117	6	9	part_of	WFA	1041:1043	arg1	Cys-272	WFA		Cys-272		Cterm	SpecificSite	WFA		Cys-272	Moreover, the engineered WFA with an amino acid substitution in Cys-272 yielded a recombinant monomeric lectin with limited binding specificity but wild-type affinity for GalNAc-terminated glycans, specifically GalNAcβ1,4GlcNAc.
28287093	4	65	gly	interleukin	752:762	arg1	lipopolysaccharide-stimulated monocytes	interleukin 6			lipopolysaccharide-stimulated monocytes	PUBTATOR		interleukin 6	3569		Secretion of interleukin 6 (IL-6) in lipopolysaccharide-stimulated monocytes was used as a prototypical assay of HDL's immunomodulatory capacity.
24333423	6	36	gly	protein	777:783	arg1	a histidine-tag	HAS2 protein			a histidine-tag	PUBTATOR		HAS2 protein	3037		To directly evaluate the effects of cholesterol on HAS activity, a recombinant human HAS2 protein with a histidine-tag was expressed as a membrane protein by using a baculovirus system, then successfully solubilized, and isolated by affinity chromatography.
28287093	6	3	gly	desialylated	1126:1137	arg1	desialylated A2HSG	desialylated A2HSG				PUBTATOR		A2HSG	197		HDL that increased IL-6 secretion were enriched in ApoC-III, di-sialylated glycans at multiple A1AT glycosylation sites and desialylated A2HSG, and depleted in mono-sialylated ApoC-III (ApoC-III1).
28287093	6	5	gly	mono-sialylated	1162:1176	arg1	ApoC-III1	ApoC-III1				Cterm		ApoC-III1	345		HDL that increased IL-6 secretion were enriched in ApoC-III, di-sialylated glycans at multiple A1AT glycosylation sites and desialylated A2HSG, and depleted in mono-sialylated ApoC-III (ApoC-III1).
28287093	6	5	gly	mono-sialylated	1162:1176	arg1	mono-sialylated ApoC-III	mono-sialylated ApoC-III				PUBTATOR		ApoC-III	345		HDL that increased IL-6 secretion were enriched in ApoC-III, di-sialylated glycans at multiple A1AT glycosylation sites and desialylated A2HSG, and depleted in mono-sialylated ApoC-III (ApoC-III1).
28287093	6	12	gly	A2HSG	1139:1143	arg1	di-sialylated glycans	A2HSG			di-sialylated glycans	PUBTATOR		A2HSG	197		HDL that increased IL-6 secretion were enriched in ApoC-III, di-sialylated glycans at multiple A1AT glycosylation sites and desialylated A2HSG, and depleted in mono-sialylated ApoC-III (ApoC-III1).
28287093	6	38	gly	di-sialylated	1063:1075	arg1	ApoC-III	ApoC-III				PUBTATOR		ApoC-III	345		HDL that increased IL-6 secretion were enriched in ApoC-III, di-sialylated glycans at multiple A1AT glycosylation sites and desialylated A2HSG, and depleted in mono-sialylated ApoC-III (ApoC-III1).
28177490	5	60	gly	3-deoxy-D-manno-oct-2-ulopyranosonic	463:498	arg1	Kdo	oct-2			Kdo	OGER		oct-2	P09086		The analyses revealed the presence of rhamnose, xylose, mannose, glucose, galacturonic acid, phosphates, 3-deoxy-D-manno-oct-2-ulopyranosonic acid (Kdo) and fatty acids (10:0, 11:0, 11:0(3-OH) i/a, 11:0(3-OH), 12:0(3-OH) i/a, 12:0(3-OH), 12:0, 13:0(3-OH) i, 13:0(3-OH) a, 13:0(3-OH), 14:0(3-OH) i/a, 14:0(3-OH) and 16:0).
28287093	5	42	gly	di-sialylated	943:955	arg1	ApoC-III2	ApoC-III2				Cterm		ApoC-III2	345		HDL from HD patients were enriched in SAA, LBP, ApoC-III, di-sialylated ApoC-III (ApoC-III2) and desialylated A2HSG.
28287093	5	42	gly	di-sialylated	943:955	arg1	di-sialylated ApoC-III	di-sialylated ApoC-III				PUBTATOR		ApoC-III	345		HDL from HD patients were enriched in SAA, LBP, ApoC-III, di-sialylated ApoC-III (ApoC-III2) and desialylated A2HSG.
28287093	5	69	gly	desialylated	982:993	arg1	desialylated A2HSG	desialylated A2HSG				PUBTATOR		A2HSG	197		HDL from HD patients were enriched in SAA, LBP, ApoC-III, di-sialylated ApoC-III (ApoC-III2) and desialylated A2HSG.
28926673	4	11	gly	containing	701:710	arg1	an IgG AND fucosylated (G2F) glycoforms	an IgG			fucosylated (G2F) glycoforms	Cterm		IgG			In this study, the disruption of two α-2,3 sialyltransferases (ST3GAL4 and ST3GAL6) from Chinese Hamster Ovary (CHO) cells was combined with protein engineering of the Fc region to generate an IgG containing 80% bigalactosylated and fucosylated (G2F) glycoforms.