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",", "911:911"], ["26916304", "4", "while", "913:917"], ["26916304", "4", "heparin", "919:925"], ["26916304", "4", "was", "927:929"], ["26916304", "4", "detected", "931:938"], ["26916304", "4", "in", "940:941"], ["26916304", "4", "1 out of 4 examined FIX concentrates", "943:978"], ["26916304", "4", ".", "979:979"], ["26916304", "5", "All heparin-containing clotting factor concentrates", "981:1031"], ["26916304", "5", "showed", "1033:1038"], ["26916304", "5", "severely hampered prohemostatic effects", "1040:1078"], ["26916304", "5", "when", "1080:1083"], ["26916304", "5", "therapeutic doses", "1085:1101"], ["26916304", "5", "were", "1103:1106"], ["26916304", "5", "added", "1108:1112"], ["26916304", "5", "to", "1114:1115"], ["26916304", "5", "anticoagulated plasmas", "1117:1138"], ["26916304", "5", ".", "1139:1139"], ["26916304", "6", "Upon", "1141:1144"], ["26916304", "6", "heparin removal", "1146:1160"], ["26916304", "6", ",", "1161:1161"], ["26916304", "6", "comparable prohemostatic 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"2308:2340"], ["28619057", "14", ".", "2341:2341"], ["28619057", "15", "Cross polarization", "2343:2360"], ["28619057", "15", "with", "2362:2365"], ["28619057", "15", "magic angle", "2367:2377"], ["28619057", "15", "spinning", "2379:2386"], ["28619057", "15", "(CP/MAS) NMR spectroscopy", "2388:2412"], ["28619057", "15", "showed", "2414:2419"], ["28619057", "15", "no apparent difference", "2421:2442"], ["28619057", "15", "in", "2444:2445"], ["28619057", "15", "the rigid and semi-rigid polysaccharides", "2447:2486"], ["28619057", "15", "in", "2488:2489"], ["28619057", "15", "the CWs", "2491:2497"], ["28619057", "15", "of", "2499:2500"], ["28619057", "15", "the three segments", "2502:2519"], ["28619057", "15", ".", "2520:2520"], ["28619057", "16", "Single-pulse excitation", "2522:2544"], ["28619057", "16", "with", "2546:2549"], ["28619057", "16", "magic-angle spinning (SPE/MAS) NMR spectroscopy", "2551:2597"], ["28619057", "16", ",", "2598:2598"], ["28619057", "16", "which", "2600:2604"], 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["28920453", "3", ",", "418:418"], ["28920453", "3", "current glycan analysis", "420:442"], ["28920453", "3", "mainly", "444:449"], ["28920453", "3", "focuses", "451:457"], ["28920453", "3", "on", "459:460"], ["28920453", "3", "the N-glycans", "462:474"], ["28920453", "3", "due", "476:478"], ["28920453", "3", "to", "480:481"], ["28920453", "3", "the absence", "483:493"], ["28920453", "3", "of", "495:496"], ["28920453", "3", "analytical tools", "498:513"], ["28920453", "3", "to", "515:516"], ["28920453", "3", "liberate", "518:525"], ["28920453", "3", "O-glycans", "527:535"], ["28920453", "3", "with", "537:540"], ["28920453", "3", "high sensitivity", "542:557"], ["28920453", "3", ".", "558:558"], ["28920453", "4", "We", "560:561"], ["28920453", "4", "developed", "563:571"], ["28920453", "4", "selective and sensitive method", "573:602"], ["28920453", "4", "to", "604:605"], ["28920453", "4", "profile native O-glycans", "607:630"], ["28920453", "4", "on", "632:633"], ["28920453", "4", "rhEPOs", "635:640"], ["28920453", "4", ".", "641:641"], ["28920453", "5", "RESULTS", "643:649"], ["28920453", "5", "O-glycosylation", "651:665"], ["28920453", "5", "on", "667:668"], ["28920453", "5", "rhEPO", "670:674"], ["28920453", "5", "including", "676:684"], ["28920453", "5", "O-acetylation", "686:698"], ["28920453", "5", "on", "700:701"], ["28920453", "5", "a sialic acid", "703:715"], ["28920453", "5", "was", "717:719"], ["28920453", "5", "comprehensively", "721:735"], ["28920453", "5", "characterized", "737:749"], ["28920453", "5", ".", "750:750"], ["28920453", "6", "Details", "752:758"], ["28920453", "6", "such", "760:763"], ["28920453", "6", "as", "765:766"], ["28920453", "6", "O-glycan structure", "768:785"], ["28920453", "6", "and", "787:789"], ["28920453", "6", "O-acetyl-modification site", "791:816"], ["28920453", "6", "were", "818:821"], ["28920453", "6", "obtained", "823:830"], ["28920453", "6", "from", "832:835"], ["28920453", "6", "tandem MS. CONCLUSION\nThis method may be applied to QC and batch analysis of not only rhEPOs but also other biotherapeutics bearing multiple O-glycosylations", "837:993"], ["28920453", "6", ".", "994:994"]], "25641685": [["25641685", "0", "MALDI-TOF MS", "0:11"], ["25641685", "0", "applied", "13:19"], ["25641685", "0", "to", "21:22"], ["25641685", "0", "apoC-III glycoforms", "24:42"], ["25641685", "0", "of", "44:45"], ["25641685", "0", "patients", "47:54"], ["25641685", "0", "with", "56:59"], ["25641685", "0", "congenital disorders", "61:80"], ["25641685", "0", "affecting", "82:90"], ["25641685", "0", "O-glycosylation", "92:106"], ["25641685", "0", ".", "107:107"], ["25641685", "1", "Comparison", "109:118"], ["25641685", "1", "with", "120:123"], ["25641685", "1", "two-dimensional electrophoresis", "125:155"], ["25641685", "1", ".", "156:156"], ["25641685", "2", "PURPOSE", "158:164"], ["25641685", "2", "The O-glycan abnormalities", "166:191"], ["25641685", "2", "accompanying", "193:204"], 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["27269286", "7", ".", "1145:1145"], ["27269286", "8", "These data", "1147:1156"], ["27269286", "8", "demonstrate", "1158:1168"], ["27269286", "8", "the functional equivalency", "1170:1195"], ["27269286", "8", "of", "1197:1198"], ["27269286", "8", "structurally dissimilar N-glycans", "1200:1232"], ["27269286", "8", "and", "1234:1236"], ["27269286", "8", "suggest", "1238:1244"], ["27269286", "8", "a self-correcting feature", "1246:1270"], ["27269286", "8", "of", "1272:1273"], ["27269286", "8", "the Golgi", "1275:1283"], ["27269286", "8", "that", "1285:1288"], ["27269286", "8", "sustains", "1290:1297"], ["27269286", "8", "cellular homeostasis", "1299:1318"], ["27269286", "8", ".", "1319:1319"]], "26507776": [["26507776", "0", "UDP-galactose transporter gene hUGT1 expression", "0:46"], ["26507776", "0", "in", "48:49"], ["26507776", "0", "tobacco plants", "51:64"], ["26507776", "0", "leads", "66:70"], ["26507776", "0", "to", "72:73"], ["26507776", "0", "hyper-galactosylated cell wall 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"chlorophyll", "369:379"], ["26507776", "1", "and", "381:383"], ["26507776", "1", "lignin", "385:390"], ["26507776", "1", ",", "391:391"], ["26507776", "1", "and", "393:395"], ["26507776", "1", "a gibberellin-responsive phenotype", "397:430"], ["26507776", "1", ".", "431:431"], ["26507776", "2", "In", "433:434"], ["26507776", "2", "the present study", "436:452"], ["26507776", "2", ",", "453:453"], ["26507776", "2", "we", "455:456"], ["26507776", "2", "demonstrated", "458:469"], ["26507776", "2", "that", "471:474"], ["26507776", "2", "hUGT1 expression", "476:491"], ["26507776", "2", "altered", "493:499"], ["26507776", "2", "the monosaccharide composition", "501:530"], ["26507776", "2", "of", "532:533"], ["26507776", "2", "cell wall matrix polysaccharides", "535:566"], ["26507776", "2", ",", "567:567"], ["26507776", "2", "such", "569:572"], ["26507776", "2", "as", "574:575"], ["26507776", "2", "pectic and hemicellulosic polysaccharides", "577:617"], ["26507776", "2", ",", "618:618"], ["26507776", "2", "which", "620:624"], ["26507776", "2", "are", "626:628"], ["26507776", "2", "biosynthesized", "630:643"], ["26507776", "2", "in", "645:646"], ["26507776", "2", "the Golgi lumen", "648:662"], ["26507776", "2", ".", "663:663"], ["26507776", "3", "An analysis", "665:675"], ["26507776", "3", "of", "677:678"], ["26507776", "3", "the monosaccharide composition", "680:709"], ["26507776", "3", "of", "711:712"], ["26507776", "3", "the cell wall matrix polysaccharides", "714:749"], ["26507776", "3", "revealed", "751:758"], ["26507776", "3", "that", "760:763"], ["26507776", "3", "the ratio", "765:773"], ["26507776", "3", "of", "775:776"], ["26507776", "3", "galactose", "778:786"], ["26507776", "3", "to", "788:789"], ["26507776", "3", "total monosaccharides", "791:811"], ["26507776", "3", "was", "813:815"], ["26507776", "3", "significantly", "817:829"], ["26507776", "3", "elevated", "831:838"], ["26507776", "3", "in", "840:841"], ["26507776", "3", "the hemicellulose II and pectin 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["26511224", "1", "previous studies", "215:230"], ["26511224", "1", "have", "232:235"], ["26511224", "1", "not", "237:239"], ["26511224", "1", "considered", "241:250"], ["26511224", "1", "variation", "252:260"], ["26511224", "1", "in", "262:263"], ["26511224", "1", "specific components", "265:283"], ["26511224", "1", "of", "285:286"], ["26511224", "1", "breast milk", "288:298"], ["26511224", "1", "that", "300:303"], ["26511224", "1", "may", "305:307"], ["26511224", "1", "affect", "309:314"], ["26511224", "1", "early development", "316:332"], ["26511224", "1", ".", "333:333"], ["26511224", "2", "OBJECTIVE", "335:343"], ["26511224", "2", "We", "345:346"], ["26511224", "2", "examined", "348:355"], ["26511224", "2", "whether", "357:363"], ["26511224", "2", "differences", "365:375"], ["26511224", "2", "in", "377:378"], ["26511224", "2", "the composition", "380:394"], ["26511224", "2", "of", "396:397"], ["26511224", "2", "human milk oligosaccharides", "399:425"], ["26511224", "2", "(", "427:427"], ["26511224", "2", "HMOs", "428:431"], ["26511224", "2", ")", "432:432"], ["26511224", "2", "correlate", "434:442"], ["26511224", "2", "with", "444:447"], ["26511224", "2", "infant growth", "449:461"], ["26511224", "2", "and", "463:465"], ["26511224", "2", "body composition", "467:482"], ["26511224", "2", "at", "484:485"], ["26511224", "2", "1 and 6 mo", "487:496"], ["26511224", "2", "of", "498:499"], ["26511224", "2", "age", "501:503"], ["26511224", "2", ".", "504:504"], ["26511224", "3", "DESIGN\nTwenty-five mother-infant dyads", "506:543"], ["26511224", "3", "were", "545:548"], ["26511224", "3", "recruited", "550:558"], ["26511224", "3", "from", "560:563"], ["26511224", "3", "the", "565:567"], ["26511224", "3", "University", "569:578"], ["26511224", "3", "Hospital", "580:587"], ["26511224", "3", "at", "589:590"], ["26511224", "3", "the", "592:594"], ["26511224", "3", "University", "596:605"], ["26511224", "3", "of", "607:608"], ["26511224", "3", "Oklahoma Health Sciences Center", "610:640"], ["26511224", "3", ".", "641:641"], ["26511224", "4", "Infants", "643:649"], ["26511224", "4", "were", "651:654"], ["26511224", "4", "breastfed", "656:664"], ["26511224", "4", "for", "666:668"], ["26511224", "4", "6 mo", "670:673"], ["26511224", "4", ".", "674:674"], ["26511224", "5", "Breast-milk and infant measures", "676:706"], ["26511224", "5", "were", "708:711"], ["26511224", "5", "obtained", "713:720"], ["26511224", "5", "at", "722:723"], ["26511224", "5", "1 and 6 mo", "725:734"], ["26511224", "5", "of", "736:737"], ["26511224", "5", "infant age", "739:748"], ["26511224", "5", ".", "749:749"], ["26511224", "6", "HMO composition", "751:765"], ["26511224", "6", "was", "767:769"], ["26511224", "6", "analyzed", "771:778"], ["26511224", "6", "by", "780:781"], ["26511224", "6", "high-pressure liquid chromatography", "783:817"], ["26511224", "6", ",", "818:818"], ["26511224", "6", "and", "820:822"], ["26511224", "6", "infant growth", "824:836"], ["26511224", "6", "(", "838:838"], ["26511224", "6", "length", "839:844"], ["26511224", "6", "and", "846:848"], ["26511224", "6", "weight", "850:855"], ["26511224", "6", ")", "856:856"], ["26511224", "6", "and", "858:860"], ["26511224", "6", "body composition", "862:877"], ["26511224", "6", "(", "879:879"], ["26511224", "6", "percentage fat", "880:893"], ["26511224", "6", ",", "894:894"], ["26511224", "6", "total fat", "896:904"], ["26511224", "6", ",", "905:905"], ["26511224", "6", "lean mass", "907:915"], ["26511224", "6", ")", "916:916"], ["26511224", "6", "were", "918:921"], ["26511224", "6", "measured", "923:930"], ["26511224", "6", "by", "932:933"], ["26511224", "6", "dual-energy X-ray absorptiometry", "935:966"], ["26511224", "6", ".", "967:967"], ["26511224", "7", "Relations", "969:977"], ["26511224", "7", "between", "979:985"], ["26511224", "7", "HMOs", "987:990"], ["26511224", "7", "and", "992:994"], ["26511224", "7", "infant growth", "996:1008"], ["26511224", "7", "and", "1010:1012"], ["26511224", "7", "body composition", "1014:1029"], ["26511224", "7", "were", "1031:1034"], ["26511224", "7", "examined", "1036:1043"], ["26511224", "7", "by", "1045:1046"], ["26511224", "7", "using", "1048:1052"], ["26511224", "7", "multiple linear regression", "1054:1079"], ["26511224", "7", ".", "1080:1080"], ["26511224", "8", "A priori covariates", "1082:1100"], ["26511224", "8", "included", "1102:1109"], ["26511224", "8", "maternal prepregnancy body mass index", "1111:1147"], ["26511224", "8", ",", "1148:1148"], ["26511224", "8", "pregnancy weight gain", "1150:1170"], ["26511224", "8", ",", "1171:1171"], ["26511224", "8", "and", "1173:1175"], ["26511224", "8", "infant age", "1177:1186"], ["26511224", "8", "and", "1188:1190"], ["26511224", "8", "sex", "1192:1194"], ["26511224", "8", ".", "1195:1195"], ["26511224", "9", "RESULTS\nHigher HMO diversity and evenness at 1 mo", "1197:1245"], ["26511224", "9", "were", "1247:1250"], ["26511224", "9", "associated", "1252:1261"], 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