doc_id	sent_index	relation_id	relation	trigger	trigger_offset	arg_num	arg_base_np	arg_protein	arg_domain	arg_site	arg_sugar	PSource	SiteSource	NProtein	NID	SiteName	sent_text
34552909	6	8	gly	modified	1140:1147	arg3	Most glycosites AND non-sialylated O-glycans			Most glycosites	non-sialylated O-glycans					glycosites	Most glycosites were modified by non-sialylated O-glycans such as HexNAc(1) and HexNAc(1)Hex (1).
34552909	6	19	gly	non-sialylated	1152:1165	arg1	non-sialylated O-glycans				non-sialylated O-glycans						Most glycosites were modified by non-sialylated O-glycans such as HexNAc(1) and HexNAc(1)Hex (1).
34552909	6	38	gly	glycosites	1124:1133	arg2	Most glycosites			Most glycosites						glycosites	Most glycosites were modified by non-sialylated O-glycans such as HexNAc(1) and HexNAc(1)Hex (1).
34552909	6	8	gly	modified	1140:1147	arg3	Most glycosites AND HexNAc(1)			glycosites	HexNAc(1)					glycosites	Most glycosites were modified by non-sialylated O-glycans such as HexNAc(1) and HexNAc(1)Hex (1).
34552909	6	19	gly	non-sialylated	1152:1165	arg1	HexNAc(1)				HexNAc(1)						Most glycosites were modified by non-sialylated O-glycans such as HexNAc(1) and HexNAc(1)Hex (1).
32290896	10	32	gly	glutamate	1972:1980	arg1	malonate, creatine, choline, myo-inositol, 2-oxoglutarate, alanine, glycerol, carnosine, histidine, glutamate			malonate, creatine, choline, myo-inositol, 2-oxoglutarate, alanine, glycerol, carnosine, histidine, glutamate						histidine	According to the variable importance in projection score, the most important metabolites to differentiate between the CON and the CHI group were hippurate, acetate, hypoxanthine, arginine, malonate, creatine, choline, myo-inositol, 2-oxoglutarate, alanine, glycerol, carnosine, histidine, glutamate and 3-hydroxyisobutyrate.
33421637	3	38	gly	glycoproteins	706:718	arg1	SMME-separated glycoproteins	SMME-separated glycoproteins				Fterm		glycoproteins			Furthermore, we have developed a fixation method for the lectin blotting of SMME-separated glycoproteins by immersing the SMME membranes into acetone solvent followed by heating.
33783000	10	3	gly	used	1111:1114	arg2	An enzyme's peptide sequence			An enzyme's peptide sequence						sequence	An enzyme's peptide sequence was obtained by mass spectrometry and used to retrieve a glucoamylase within the annotated genome of A. wentii v1.0.
32488610	3	12	part_of	papain	527:532	arg1	papain catalytic Z-Ala-His	papain		papain catalytic Z-Ala-His		Fterm	Site	papain		Z-Ala-His	The effects of reaction conditions on the yield of papain catalytic Z-Ala-His were systematically investigated with the highest yield of 68.4%, which was higher than free papain (63.3%).
33934170	0	8	part_of	Impact	0:5	arg1	Composition	Impact		Composition		OGER	Site	Impact	Q9P2X3	position	Impact of Cashew (Anacardium occidentale L.) by-Product on Composition and Metabolic Activity of Human Colonic Microbiota In Vitro Indicates Prebiotic Properties.
33379036	1	57	gly	N-glycoproteins	205:219	arg1	numerous N-glycoproteins	numerous N-glycoproteins				Fterm		N-glycoproteins			Human milk contains numerous N-glycoproteins with functions that provide protection to the infant.
32171829	3	19	part_of	LCK	612:614	arg1	The fabricated LCK hybrid composite	LCK		The fabricated LCK hybrid composite		OGER	Site	LCK	P06239	composite	The fabricated LCK hybrid composite was characterized using XRD, SEM, BET, EDAX, TGA-DTA and FTIR analysis.
33916867	5	25	part_of	UBF	542:544	arg1	The chemical composition	UBF		The chemical composition		OGER	Site	UBF	P17480	position,	The chemical composition, physico-chemical properties, and functional properties of UBF, as well as its application in bread for wheat flour (WF) substitution at different levels, were investigated.
33379036	6	91	gly	glycosylation	1457:1469	arg2	glycosylation site			glycosylation site						site	We compared the capacity of higher-energy collision dissociation, electron-transfer dissociation and electron-transfer/higher-energy collision dissociation (EThcD) to produce fragment ions that would enable effective identification of the glycan composition, peptide sequence and glycosylation site.
32761170	3	82	part_of	proteins	461:468	arg1	composition	proteins		composition		Fterm	Site	proteins		position	In this study, we have used microscopy, phylogenomics, and proteomics to examine the composition and evolution of cell envelope proteins in Tuwongella immobilis and other members of the Planctomycetes.
34988116	6	53	gly	HexNAc	1564:1569	arg1	HNK-1 epitope			HNK-1 epitope	HNK-1 epitope						In particular, 3-O-sulfation of terminal Gal was commonly found, whereas terminal sulfated HexNAc as in GalNAcβ1-4GlcNAc (LacdiNAc), and 3-O-sulfated hexuronic acid as in HNK-1 epitope (SO3-3GlcAβ1-3Galβ1-4GlcNAc) were identified only in the brain and not in the intestine or ovaries analyzed in parallel.
34076032	6	56	gly	sialylated	1018:1027	arg1	a sialylated glycan				a sialylated glycan						Interestingly, a sialylated glycan also has a remarkable inhibitory effect on the gel formation, which highlights the high selectivity of the gel dynamic response system.
33908003	6	35	gly	glycopeptide	920:931	arg2	glycopeptide			glycopeptide						glycopeptide	In this chapter, we described a glycopeptide enrichment method combining strong anion exchange, electrostatic repulsion, and hydrophilic interaction chromatography (SAX-ERLIC).
33808946	0	43	part_of	Short	22:26	arg1	a Short Peptide	Short		a Short Peptide		OGER		Short			Hyaluronic Acid and a Short Peptide Improve the Performance of a PCL Electrospun Fibrous Scaffold Designed for Bone Tissue Engineering Applications.
32718649	1	50	part_of	kaolin	157:162	arg1	modified magnetic kaolin (CS/kaolin/Fe3O4) composite	kaolin		modified magnetic kaolin (CS/kaolin/Fe3O4) composite		Fterm	Site	kaolin		composite	Chitosan modified magnetic kaolin (CS/kaolin/Fe3O4) composite was prepared by a facile one-pot coprecipitation method and used for the removal of methyl orange (MO) from aqueous medium.
34575987	6	54	part_of	angiotensin	1180:1190	arg1	atrial natriuretic peptide	angiotensin II		atrial natriuretic peptide		PUBTATOR	Site	angiotensin II	24179	peptide	Transcriptome analyses demonstrated that the protective effects of developing heart failure were accompanied by down-regulating of the Natriuretic Peptide A gene expression and by decreasing the concentrations of angiotensin II and atrial natriuretic peptide in plasma.
34575987	6	64	part_of	Natriuretic	1102:1112	arg1	the Natriuretic Peptide	Natriuretic Peptide A		the Natriuretic Peptide		PUBTATOR		Natriuretic Peptide A	24602		Transcriptome analyses demonstrated that the protective effects of developing heart failure were accompanied by down-regulating of the Natriuretic Peptide A gene expression and by decreasing the concentrations of angiotensin II and atrial natriuretic peptide in plasma.
32409064	1	55	part_of	G2-β-CD	244:250	arg1	6-O-α-maltosyl-β-cyclodextrin (G2-β-CD) composite	-CD		6-O-α-maltosyl-β-cyclodextrin (G2-β-CD) composite		PUBTATOR	Site	-CD	65057	composite	In this work, we have fabricated nafion (NF) stabilized black phosphorus nanosheets (BPNSs) and 6-O-α-maltosyl-β-cyclodextrin (G2-β-CD) composite (BPNSs-G2-β-CD) as novel electrochemical sensoring platform for chiral recognition of tryptophan (Trp) enantiomers.
32155970	8	81	part_of	CS-g-CNO	1303:1310	arg1	composites	CNO		composites		PUBTATOR	Site	CNO	Q9NUP1	composites	Still, a faster degradation (weight loss and pH changes) was obtained with composites of CS-g-CNO due to a higher SBF interaction by hydrogen bonding.
34552909	1	70	gly	glycosylated	69:80	arg1	The densely glycosylated spike (S) proteins	The densely glycosylated spike (S) proteins				Fterm		proteins			The densely glycosylated spike (S) proteins that are highly exposed on the surface of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) facilitate viral attachment, entry, and membrane fusion.
33811724	3	39	part_of	CIP-loaded	516:525	arg1	the CIP-loaded composite	CIP		the CIP-loaded composite		OGER	Site	CIP	Q5VWP3	composite	A synergistic effect of CS and CIP contents on the compressive strength of the CIP-loaded composite was evidenced.
32812835	7	2	gly	afucosylated	1339:1350	arg1	afucosylated N-glycans				afucosylated N-glycans						These experiments suggest that afucosylated N-glycans are not critical for the in vitro phagocytic activity of a recombinant antibody whose target is aggregated Aβ and uses Fc effector function as part of its MOA.
34847186	8	51	part_of	protein	1203:1209	arg1	protein domains	protein		protein domains		Fterm	Site	protein		domains	We hypothesize that the "Y"- shape of dimeric Fc fusions cause steric hindrance between protein domains and leads to physical instability.
34988116	2	39	gly	sialylated	582:591	arg1	Galβ1-4GlcNAc				Galβ1-4GlcNAc						Unambiguous identification of adult zebrafish glycotopes is particularly challenging due to the presence of extra β4-galactosylation on the basic building block of Galβ1-4GlcNAc that can be fucosylated and variably sialylated by N-acetyl, N-glycolyl, or deaminated neuraminic acids.
33908003	4	3	gly	nonglycosylated	748:762	arg1	nonglycosylated peptides			nonglycosylated peptides						peptides	However, such analysis is often complicated by extensive glycan diversity and the low abundance of glycopeptides in a complex mixture relative to nonglycosylated peptides.
33908003	4	26	gly	glycopeptides	701:713	arg1	extensive glycan diversity			glycopeptides	extensive glycan diversity					glycopeptides	However, such analysis is often complicated by extensive glycan diversity and the low abundance of glycopeptides in a complex mixture relative to nonglycosylated peptides.
34847186	6	2	part_of	domain	859:864	arg1	an IgG1	IgG1		domain		OGER	Site	IgG1	P01857	domain	Here we show for the first time the transient expression in Nicotiana benthamiana of rPA fused to the immunoglobulin fragment crystallizable (Fc) domain on an IgG1, a strategy commonly used to improve the stability of therapeutic proteins.
33955492	2	63	part_of	proteins	317:324	arg1	composition	proteins		composition		Fterm	Site	proteins		position	For quality, the content and composition of seed storage proteins (SSPs) determine the elasticity of wheat dough and flour processing quality.
34062407	6	8	part_of	peptide	924:930	arg1	the exendin-4 (Ex-4) peptide	glucagon-like peptide 1		the exendin-4 (Ex-4) peptide		PUBTATOR	Site	glucagon-like peptide 1	2641	peptide	The primary focus of this study was to assess the ability of the exendin-4 (Ex-4) peptide, a glucagon-like peptide 1 (GLP-1) receptor agonist, to induce tenocyte differentiation in bone marrow-derived human mesenchymal stem cells (hMSCs).
34062407	6	56	part_of	glucagon-like	910:922	arg1	the exendin-4 (Ex-4) peptide	glucagon-like peptide 1		the exendin-4 (Ex-4) peptide		PUBTATOR	Site	glucagon-like peptide 1	2641	peptide	The primary focus of this study was to assess the ability of the exendin-4 (Ex-4) peptide, a glucagon-like peptide 1 (GLP-1) receptor agonist, to induce tenocyte differentiation in bone marrow-derived human mesenchymal stem cells (hMSCs).
34062407	6	67	part_of	GLP-1	935:939	arg1	the exendin-4 (Ex-4) peptide	GLP-1		the exendin-4 (Ex-4) peptide		PUBTATOR	Site	GLP-1	2740	peptide	The primary focus of this study was to assess the ability of the exendin-4 (Ex-4) peptide, a glucagon-like peptide 1 (GLP-1) receptor agonist, to induce tenocyte differentiation in bone marrow-derived human mesenchymal stem cells (hMSCs).
33599092	8	68	gly	glycopeptides	1525:1537	arg2	IgG glycopeptides			IgG glycopeptides						glycopeptides	CONCLUSIONS AND CLINICAL RELEVANCE Through the simple and high-throughput procedures, this study revealed the important role of IgG glycopeptides in the premature pathology of CRC.
33143222	4	1	part_of	LM2	749:751	arg1	LM2 (AGPs) epitopes	LM2 (AGPs		LM2 (AGPs) epitopes		OGER	Site	LM2 (AGPs	O00116	epitopes	Based on the obtained results, it can be concluded that (1) the LM6 (pectic), LM2 (AGPs) epitopes are positive markers, but the LM5, LM19 (pectic), JIM8, JIM13 (AGPs) epitopes are negative markers of cells reprogramming to the meristematic/pluripotent state; (2) the LM8 (pectic), JIM8, JIM13, LM2 (AGPs) and JIM11 (extensin) epitopes are positive markers, but LM6 (pectic) epitope is negative marker of cells undergoing detachment; (3) JIM4 (AGPs) is a positive marker, but LM5 (pectic), JIM8, JIM13, LM2 (AGPs) are negative markers for pericycle cells on the xylem pole; (4) LM19, LM20 (pectic), JIM13, LM2 (AGPs) are constitutive wall components, but LM6, LM8 (pectic), JIM4, JIM8, JIM16 (AGPs), JIM11, JIM12 and JIM20 (extensins) are not constitutive wall components; (5) the extensins do not contribute to the cell reprogramming.
33143222	4	9	part_of	AGPs	754:757	arg1	LM2 (AGPs) epitopes	LM2 (AGPs		LM2 (AGPs) epitopes		OGER	Site	LM2 (AGPs	O00116	epitopes	Based on the obtained results, it can be concluded that (1) the LM6 (pectic), LM2 (AGPs) epitopes are positive markers, but the LM5, LM19 (pectic), JIM8, JIM13 (AGPs) epitopes are negative markers of cells reprogramming to the meristematic/pluripotent state; (2) the LM8 (pectic), JIM8, JIM13, LM2 (AGPs) and JIM11 (extensin) epitopes are positive markers, but LM6 (pectic) epitope is negative marker of cells undergoing detachment; (3) JIM4 (AGPs) is a positive marker, but LM5 (pectic), JIM8, JIM13, LM2 (AGPs) are negative markers for pericycle cells on the xylem pole; (4) LM19, LM20 (pectic), JIM13, LM2 (AGPs) are constitutive wall components, but LM6, LM8 (pectic), JIM4, JIM8, JIM16 (AGPs), JIM11, JIM12 and JIM20 (extensins) are not constitutive wall components; (5) the extensins do not contribute to the cell reprogramming.
33143222	4	31	part_of	JIM11	980:984	arg1	the LM8 (pectic), JIM8, JIM13, LM2 (AGPs) and JIM11 (extensin) epitopes	JIM11 (extensin		the LM8 (pectic), JIM8, JIM13, LM2 (AGPs) and JIM11 (extensin) epitopes		PUBTATOR	Site	JIM11 (extensin	100833457	epitopes	Based on the obtained results, it can be concluded that (1) the LM6 (pectic), LM2 (AGPs) epitopes are positive markers, but the LM5, LM19 (pectic), JIM8, JIM13 (AGPs) epitopes are negative markers of cells reprogramming to the meristematic/pluripotent state; (2) the LM8 (pectic), JIM8, JIM13, LM2 (AGPs) and JIM11 (extensin) epitopes are positive markers, but LM6 (pectic) epitope is negative marker of cells undergoing detachment; (3) JIM4 (AGPs) is a positive marker, but LM5 (pectic), JIM8, JIM13, LM2 (AGPs) are negative markers for pericycle cells on the xylem pole; (4) LM19, LM20 (pectic), JIM13, LM2 (AGPs) are constitutive wall components, but LM6, LM8 (pectic), JIM4, JIM8, JIM16 (AGPs), JIM11, JIM12 and JIM20 (extensins) are not constitutive wall components; (5) the extensins do not contribute to the cell reprogramming.
34673798	5	58	part_of	CMOs	1357:1360	arg1	composition	CMOs		composition		Cterm	Site	CMOs		position	Inulin and bacitracin inclusion in the basal diet did not change significantly the composition or diversity of these CMOs.
31937642	11	50	gly	N-glycopeptides	1892:1906	arg2	human milk and mucosal fucosylated N-glycopeptides			human milk and mucosal fucosylated N-glycopeptides						N-glycopeptides	GlcNAc-Asn hydrolysis generates aspartate and GlcNAc, which is used as a fermentable source by L.casei These data establish the existence in a commensal bacterial species of an exclusive metabolic pathway likely to scavenge human milk and mucosal fucosylated N-glycopeptides in the gastrointestinal tract.IMPORTANCE The gastrointestinal tract accommodates more than 1014 microorganisms that have an enormous impact on human health.
31937642	11	118	gly	fucosylated	1880:1890	arg1	human milk and mucosal fucosylated N-glycopeptides			human milk and mucosal fucosylated N-glycopeptides						N-glycopeptides	GlcNAc-Asn hydrolysis generates aspartate and GlcNAc, which is used as a fermentable source by L.casei These data establish the existence in a commensal bacterial species of an exclusive metabolic pathway likely to scavenge human milk and mucosal fucosylated N-glycopeptides in the gastrointestinal tract.IMPORTANCE The gastrointestinal tract accommodates more than 1014 microorganisms that have an enormous impact on human health.
34552909	4	1	part_of	de-N-glycosylation	567:584	arg1	trypsin/Glu-C	N		trypsin/Glu-C		PUBTATOR	Site	N	43740575	trypsin/Glu-C	Following digestion with trypsin and trypsin/Glu-C, and de-N-glycosylation using PNGase F, we determined the GalNAc-type O-glycosylation pattern of S proteins, including O-glycosites and the six most common O-glycans occupying them, via Byonic identification and manual validation.
34552909	4	64	part_of	S	659:659	arg1	O-glycosites	S proteins		O-glycosites		Cterm	Site	S proteins	43740568	O-glycosites	Following digestion with trypsin and trypsin/Glu-C, and de-N-glycosylation using PNGase F, we determined the GalNAc-type O-glycosylation pattern of S proteins, including O-glycosites and the six most common O-glycans occupying them, via Byonic identification and manual validation.
32887022	4	85	part_of	troponin	884:891	arg1	atrial natriuretic peptide	troponin I		atrial natriuretic peptide		Cterm	Site	troponin I		peptide	ELISA method was used to detecte the levels of atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), troponin I (cTnI), creatine kinase (CK), angiotensin II (Ang II), aldosterone (ALD), arginine pressurization AVP, Renin, Endothelin (ET-1), Nitric Oxide (NO), AQP2 in urine.
32812835	0	64	gly	afucosylated	26:37	arg1	afucosylated glycoforms				afucosylated glycoforms						Assessment of the role of afucosylated glycoforms on the in vitro antibody-dependent phagocytosis activity of an antibody to Aβ aggregates.
34286807	0	46	gly	glycosylated	36:47	arg1	glycosylated protein	glycosylated protein				Fterm		protein			Preparation and characterization of glycosylated protein nanoparticles for astaxanthin mitochondria targeting delivery.
32817557	5	23	part_of	enzymes	791:797	arg1	catalytic residues	enzymes		catalytic residues		Fterm	Site	enzymes		residues	By mutating catalytic residues of two such enzymes, we engineered mucin-selective binding agents with retained glycoform preferences.
32979942	5	25	gly	glycoprotein	739:750	arg1	the recombinant glycoprotein glycans				the recombinant glycoprotein glycans						Compositions of the N-linked glycans from the native spikes were analyzed by mass spectrometry, which revealed overall processing states of the native glycans highly similar to that of the recombinant glycoprotein glycans.
32513541	0	34	part_of	arg-gly-asp	83:93	arg1	arg-gly-asp tripeptides	arg		arg-gly-asp tripeptides		OGER	Site	arg	Q9P2R6	tripeptides	Improved human islets' viability and functionality with mesenchymal stem cells and arg-gly-asp tripeptides supplementation of alginate micro-encapsulated islets in vitro.
34398423	9	72	gly	used	1431:1434	arg2	Nanoencapsulated lipopeptides			Nanoencapsulated lipopeptides						lipopeptides	Nanoencapsulated lipopeptides could be used as a potential delivery system of lipopeptides to improve their anti-adhesive effect against C. albicans cells colonizing medical devices and their anti-infectious activity against leishmania.
34735907	6	2	part_of	composition	522:532	arg1	IBD	IBD		composition		OGER	Site	IBD	Q9UKU7	position	Research about the effect of JXR on IBD and the active ingredient composition of JXR remains deficiency.
32171829	2	21	part_of	LCK	492:494	arg1	lanthanum encapsulated chitosan-kaolin clay (LCK) hybrid composite	LCK		lanthanum encapsulated chitosan-kaolin clay (LCK) hybrid composite		OGER	Site	LCK	P06239	composite	The present work investigates the adsorption performance and mechanism of lanthanum encapsulated chitosan-kaolin clay (LCK) hybrid composite was prepared and utilized for the remediation of nitrate and phosphate from water.
32171829	2	28	part_of	chitosan-kaolin	470:484	arg1	lanthanum encapsulated chitosan-kaolin clay (LCK) hybrid composite	chitosan-kaolin		lanthanum encapsulated chitosan-kaolin clay (LCK) hybrid composite		Fterm	Site	chitosan-kaolin		composite	The present work investigates the adsorption performance and mechanism of lanthanum encapsulated chitosan-kaolin clay (LCK) hybrid composite was prepared and utilized for the remediation of nitrate and phosphate from water.
34364607	3	51	part_of	PPy/Ag	697:702	arg1	resultant PPy/Ag composite	PPy		resultant PPy/Ag composite		OGER	Site	PPy	P01298	composite	It was found the optimal molar ratio of Py to silver nitrate was 1:1.5 with 0.02 M SDS under the reaction time of 10 h. Then, the microstructure and properties of resultant PPy/Ag composite were analyzed by scanning electron microscope (SEM), Fourier infrared spectrometer (FT-IR), X-ray diffraction spectroscopy (XRD), X-ray photoelectron spectroscopy (XPS), Raman spectroscopy and the thermogravimetry analysis (TGA), respectively.
32817557	3	13	part_of	mucin	528:532	arg1	mucin domains	mucin		mucin domains		PUBTATOR	Site	mucin	100508689	domains	These correlations have been challenging to uncover and establish because tools that specifically probe mucin domains are lacking.
32565421	8	4	part_of	EC-Hep	1214:1219	arg1	The EC-Hep composite	Hep		The EC-Hep composite		OGER	Site	Hep	Q9Y251	composite	RESULTS The EC-Hep composite allowed sustained release of growth factors.
32544582	9	8	part_of	Cal	1097:1099	arg1	Cal A composites	Cal A		Cal A composites		OGER	Site	Cal A	Q9HD26	composites	The present investigations are known to be the first and foremost study to discriminate the potentiality of Cal A composites.
32544582	9	43	part_of	A	1101:1101	arg1	Cal A composites	Cal A		Cal A composites		OGER	Site	Cal A	Q9HD26	composites	The present investigations are known to be the first and foremost study to discriminate the potentiality of Cal A composites.
32466125	9	40	part_of	gut	1294:1296	arg1	gut microbiota composition	gut		gut microbiota composition		PUBTATOR	Site	gut	110006	position	All HMO-fortified diets altered gut microbiota composition and mRNA expression in the gastrointestinal tract, albeit differently according to sex.
33805875	0	42	part_of	Collagen	65:72	arg1	Bacterial Cellulose/Fish Collagen Composites-A	Fish Collagen		Bacterial Cellulose/Fish Collagen Composites-A		OGER	Site	Fish Collagen	Q5TCZ1	Composites-A	Enzymatic and Chemical Cross-Linking of Bacterial Cellulose/Fish Collagen Composites-A Comparative Study.
33805875	0	47	part_of	Cellulose/Fish	50:63	arg1	Bacterial Cellulose/Fish Collagen Composites-A	Fish Collagen		Bacterial Cellulose/Fish Collagen Composites-A		OGER	Site	Fish Collagen	Q5TCZ1	Composites-A	Enzymatic and Chemical Cross-Linking of Bacterial Cellulose/Fish Collagen Composites-A Comparative Study.
32718649	8	35	part_of	CS/kaolin/Fe3O4	1105:1119	arg1	the CS/kaolin/Fe3O4 composite	CS		the CS/kaolin/Fe3O4 composite		PUBTATOR	Site	CS	1431	composite	The results suggested that the modification with CS broadened the application scope of kaolin in anionic species removal and the CS/kaolin/Fe3O4 composite could be a promising adsorbent for wastewater treatment.
34724615	4	7	part_of	NGF	797:799	arg1	A novel NGF@CSNPs/OBC nanocomposite	NGF		A novel NGF@CSNPs/OBC nanocomposite		OGER	Site	NGF	P01138	nanocomposite	A novel NGF@CSNPs/OBC nanocomposite with antibacterial activity, biodegradability, and porous microstructure was successfully developed.
33845441	4	31	gly	used	560:563	arg2	A reduced graphene oxide-chitosan-gold nanoparticles composite			A reduced graphene oxide-chitosan-gold nanoparticles composite						composite	A reduced graphene oxide-chitosan-gold nanoparticles composite was used as a biocompatible substrate for the receptor stabilization.
32204068	1	2	part_of	NIPA-co-MBA	359:369	arg1	carboxymethyl fenugreek galactomannang-g-poly(N-isopropylacrylamide-co-N,N'-methylene-bis-acrylamide)-bentonite [CFG-g-P(NIPA-co-MBA)-BEN] based nanocomposites	CFG-g-P(NIPA		carboxymethyl fenugreek galactomannang-g-poly(N-isopropylacrylamide-co-N,N'-methylene-bis-acrylamide)-bentonite [CFG-g-P(NIPA-co-MBA)-BEN] based nanocomposites		OGER	Site	CFG-g-P(NIPA	Q86WB0	nanocomposites	The current study dealt with the synthesis and characterization of carboxymethyl fenugreek galactomannang-g-poly(N-isopropylacrylamide-co-N,N'-methylene-bis-acrylamide)-bentonite [CFG-g-P(NIPA-co-MBA)-BEN] based nanocomposites (NCs) as erlotinib (ERL)-delivery devices for lung cancer cells to suppress excessive cell proliferation.
32204068	1	68	part_of	[CFG-g-P	350:357	arg1	carboxymethyl fenugreek galactomannang-g-poly(N-isopropylacrylamide-co-N,N'-methylene-bis-acrylamide)-bentonite [CFG-g-P(NIPA-co-MBA)-BEN] based nanocomposites	CFG-g-P(NIPA		carboxymethyl fenugreek galactomannang-g-poly(N-isopropylacrylamide-co-N,N'-methylene-bis-acrylamide)-bentonite [CFG-g-P(NIPA-co-MBA)-BEN] based nanocomposites		OGER	Site	CFG-g-P(NIPA	Q86WB0	nanocomposites	The current study dealt with the synthesis and characterization of carboxymethyl fenugreek galactomannang-g-poly(N-isopropylacrylamide-co-N,N'-methylene-bis-acrylamide)-bentonite [CFG-g-P(NIPA-co-MBA)-BEN] based nanocomposites (NCs) as erlotinib (ERL)-delivery devices for lung cancer cells to suppress excessive cell proliferation.
32112830	2	24	gly	used	379:382	arg2	Reduced graphene oxide/silver nanocomposites			Reduced graphene oxide/silver nanocomposites						nanocomposites	Reduced graphene oxide/silver nanocomposites, rGO/Ag, were also used into the mats due to the strong antibacterial activity of rGO/Ag nanocomposites.
32756631	10	30	part_of	PVA/PEC	1858:1864	arg1	PVA/PEC composites	PVA		PVA/PEC composites		OGER	Site	PVA	P32926	composites	In addition, PVA/PEC composites have better mechanical properties owing to their harder backbones of chitosan, formation of phosphonate bonds and the PVA molecular chain movement blocked by PEC.
33908003	7	73	gly	glycopeptides	1181:1193	arg2	glycopeptides			glycopeptides						glycopeptides	Following enzymatic digestion of proteins into peptides, SAX-ERLIC is performed by solid phase extraction to enrich glycopeptides from biological samples with subsequent LC-MS/MS analysis.
32577656	6	18	gly	N-glycosylation	1211:1225	arg1	known glycan sites				known glycan sites						In order to aid structure-based design and analysis of the spike glycoprotein, CoV3D permits visualization and download of spike structures with modeled N-glycosylation at known glycan sites, and contains structure-based classification of spike conformations, generated by unsupervised clustering.
32577656	6	35	gly	glycoprotein	1123:1134	arg1	the spike glycoprotein	the spike glycoprotein				Fterm		glycoprotein			In order to aid structure-based design and analysis of the spike glycoprotein, CoV3D permits visualization and download of spike structures with modeled N-glycosylation at known glycan sites, and contains structure-based classification of spike conformations, generated by unsupervised clustering.
33075342	9	59	gly	used	1499:1502	arg2	nanocomposites			nanocomposites						nanocomposites	The prepared samples could be potentially used as coatings, emulsifiers, and nanocomposites reinforcing agents.
31972331	4	49	part_of	protein	676:682	arg1	the protein domains	protein		the protein domains		Fterm	Site	protein		domains	In order to gain a further understanding of the protein domains regulating its intracellular fate, we cloned a full-length cDNA from rTG into the pcDNA6/V5-His B expression vector.
32408255	6	81	gly	glycoprotein	1145:1156	arg1	glycoprotein (PRG4) recruitment	glycoprotein (PRG4) recruitment				Fterm		glycoprotein			Clear evidence of glycoprotein (PRG4) recruitment by Chi-C increased the softness of SyCF, which also improved nanoscale lubrication in vitro, decreasing the friction coefficient from 0.06 to 0.03.
32817557	1	55	part_of	mucin	131:135	arg1	Densely O-glycosylated mucin domains	mucin		Densely O-glycosylated mucin domains		PUBTATOR	Site	mucin	100508689	domains	Densely O-glycosylated mucin domains are found in a broad range of cell surface and secreted proteins, where they play key physiological roles.
35515389	4	84	gly	glycoproteins	795:807	arg1	salivary glycoproteins	salivary glycoproteins				Fterm		glycoproteins			A method combining the lectin microarray and lectin blotting was employed to investigate and confirm the altered glycopatterns in salivary glycoproteins.
32561280	4	45	part_of	phosphatase	1074:1084	arg1	the deposition	alkaline phosphatase		the deposition		PUBTATOR	Site	alkaline phosphatase	250	position	The hydrogel could enhance the deposition of minerals and the activity of alkaline phosphatase (ALP), in large part attributable to the oxygen and amine-containing functional groups of GO and CS.
34321166	2	7	gly	glycoprotein	677:688	arg1	glycoprotein IIb/IIIa inhibitors	glycoprotein IIb/IIIa inhibitors				Fterm		glycoprotein			Whether this advantage persists in patients at high risk of bleeding according to contemporary practice characterized by frequent use of radial-artery access and novel P2Y12 inhibitors, and low use of glycoprotein IIb/IIIa inhibitors (GPIs) is unclear.
34871808	3	95	part_of	Matrigel	549:556	arg1	the complex compositions	Matrigel		the complex compositions		Cterm	Site	Matrigel		positions	Because of the complex compositions of Matrigel and thousands of identical peptides shared between Matrigel and organoids, insufficiently dissolved Matrigel could influence proteomic analysis of organoids in multiple ways.
32119847	5	72	gly	glycopeptides	771:783	arg2	glycopeptides			glycopeptides						glycopeptides	However, the m/z distribution of glycopeptides is different to that of unmodified peptides because of their large glycan structures.
32679636	12	53	part_of	PPy/CMC	1933:1939	arg1	PPy/CMC composite	PPy		PPy/CMC composite		OGER	Site	PPy	P01298	composite	The results showed that the hydrogen bondings and Van der Waals interactions are dominant forces between the two studied dyes and PPy/CMC composite.
32285052	4	47	part_of	pyrin	1007:1011	arg1	(NOD)-like receptor family pyrin domain	pyrin		(NOD)-like receptor family pyrin domain		OGER	Site	pyrin	O15553	domain	LRE inhibited intestinal inflammation by regulating nuclear factor-κB (NF-κB) and mitogen-activated protein kinase (MAPK) pathways, restored intestinal immune homeostasis by regulating immune cell infiltration and T lymphocyte subsets, and suppressed (NOD)-like receptor family pyrin domain containing 3 (NLRP3) inflammasome activation.
32816991	3	0	part_of	have	535:538	arg1	cellobiohydrolase II AND similar catalytic domains	cellobiohydrolase II		similar catalytic domains		Fterm	Site	cellobiohydrolase		domains	Cellobiohydrolase A from the bacterium Cellulomonas fimi (CfCel6B) and cellobiohydrolase II from the fungus Trichoderma reesei (TrCel6A) have similar catalytic domains (CDs) and show similar hydrolytic activity.
32816991	3	0	part_of	have	535:538	arg1	Cellobiohydrolase A AND similar catalytic domains	Cellobiohydrolase A		similar catalytic domains		Cterm	Site	Cellobiohydrolase A		domains	Cellobiohydrolase A from the bacterium Cellulomonas fimi (CfCel6B) and cellobiohydrolase II from the fungus Trichoderma reesei (TrCel6A) have similar catalytic domains (CDs) and show similar hydrolytic activity.
34390125	2	34	gly	composition	388:398	arg1	the genetic determinants			position	the genetic determinants					position	Here, we aimed to clarify the genetic determinants of body composition in individuals with type 2 diabetes.
33379036	7	113	gly	N-glycopeptide	1604:1617	arg2	human milk N-glycopeptide profiling			human milk N-glycopeptide profiling						N-glycopeptide	Of these methods, a combination of EtOH precipitation, HILIC-SPE and EThcD-fragmentation was the most effective for human milk N-glycopeptide profiling.
34965723	5	16	gly	glycopeptides	782:794	arg2	The synthesized ACTIVE glycopeptides			The synthesized ACTIVE glycopeptides						glycopeptides	The synthesized ACTIVE glycopeptides with intrinsic icephilicity could localize on the membrane surface of human erythrocytes and improve cryopreservation with trehalose, so that remarkable post-thaw cryosurvival of human erythrocytes was achieved with a slight variation in cell morphology and functions.
32561280	2	57	gly	used	736:739	arg2	The PNIPAAm copolymer/GO composite			The PNIPAAm copolymer/GO composite						composite	The PNIPAAm copolymer/GO composite was synthesized by free-radical copolymerization of (N-isopropylacrylamide) (NIPAAm), itaconic acid (IA) and maleic anhydride-modified poly(ethylene glycol) (PEG) in the presence of GO and used for the preparation of the hydrogels.
32428561	1	45	gly	glycosylated	127:138	arg1	highly glycosylated proteins	highly glycosylated proteins				Fterm		proteins			Mucins are highly glycosylated proteins that are characterized by a higher proportion of threonine, serine, and proline residues in their sequences.
33908003	3	58	gly	glycopeptides	491:503	arg2	intact glycopeptides			intact glycopeptides						glycopeptides	In particular, the analysis of intact glycopeptides by mass spectrometry allows information about glycan location and composition to be ascertained.
32553962	10	14	part_of	LCB	1426:1428	arg1	The LCB composite	LCB		The LCB composite		OGER	Site	LCB	P09497	composite	The LCB composite showed remarkable adsorption-desorption efficiency for dye removal in water/wastewater treatment process; hence it can be considered as a competent and potential adsorbent for dye removal.
34056092	3	10	gly	O-glycoproteins	282:296	arg1	mucins-high molecular weight O-glycoproteins	mucins-high molecular weight O-glycoproteins				Fterm		O-glycoproteins			The primary components of mucus hydrogels are mucins-high molecular weight O-glycoproteins that adopt extended linear structures.
32171829	4	11	part_of	LCK	751:753	arg1	the LCK composite	LCK		the LCK composite		OGER	Site	LCK	P06239	composite	The removal of nitrate and phosphate onto the LCK composite defined by pseudo-second-order kinetic model whereas the isotherms are described by Freundlich adsorption isotherm model and thermodynamic experiments showed spontaneous and exothermic nature of the adsorption process.
34564432	4	14	gly	isoform	530:536	arg1	Man-Tf	isoform			Man-Tf	Fterm		isoform			We found that a unique mannosylated-glycan is carried by a Tf isoform in CSF (Man-Tf).
34053305	4	30	part_of	deposition	602:611	arg1	SBF	SBF		deposition		OGER	Site	SBF	O70230	position	The cements could induce the deposition of Ca-P layer in SBF.
33080108	8	83	part_of	rhBMP-2	1121:1127	arg1	CHA composite	rhBMP-2		CHA composite		OGER	Site	rhBMP-2	P12643	composite	METHODS The rhBMP-2-loaded microspheres and CHA composite (rhBMP-2 microspheres/CHA) were prepared and were used for implantation of the rats.
33080108	8	149	part_of	CHA	1106:1108	arg1	CHA composite	CHA		CHA composite		OGER	Site	CHA	Q9UL49	composite	METHODS The rhBMP-2-loaded microspheres and CHA composite (rhBMP-2 microspheres/CHA) were prepared and were used for implantation of the rats.
32745549	6	16	part_of	SA-CIS/ZnS-SBA15-NH2	1086:1105	arg1	The resultant SA-CIS/ZnS-SBA15-NH2 (QDs-silica) composite	CIS		The resultant SA-CIS/ZnS-SBA15-NH2 (QDs-silica) composite		OGER	Site	CIS	Q9NSE2	composite	The resultant SA-CIS/ZnS-SBA15-NH2 (QDs-silica) composite possessed remarkable biocompatibility towards lung cancer (A549) and kidney (HEK 293) cell lines making it a versatile material for theranostic applications.
34965723	7	2	gly	glycopeptide	1374:1385	arg2	glycopeptide			glycopeptide						glycopeptide	Analyses of differential scanning calorimetry, Raman spectroscopy, and dynamic ice shaping suggested that this cryopreservation protocol combined with the ACTIVE glycopeptide and trehalose could enhance the hydrogen bond network in nonfrozen solutions, resulting in inhibition of recrystallization and growth of ice.
33093930	1	6	gly	heterogeneity	86:98	arg1	glycans				glycans						The heterogeneity, mobility and complexity of glycans in glycoproteins have been, and currently remain, significant challenges in structural biology.
33093930	1	12	gly	glycans	128:134	arg1	glycoproteins	glycoproteins			glycans	Fterm		glycoproteins			The heterogeneity, mobility and complexity of glycans in glycoproteins have been, and currently remain, significant challenges in structural biology.
33093930	1	35	gly	glycoproteins	139:151	arg1	glycoproteins	glycoproteins				Fterm		glycoproteins			The heterogeneity, mobility and complexity of glycans in glycoproteins have been, and currently remain, significant challenges in structural biology.
34050560	6	63	part_of	protein	1228:1234	arg1	protein composition	protein		protein composition		Fterm	Site	protein		position,	RESULTS High-protein diets aggravated acute DSS-induced colitis independent of protein composition, while broad-spectrum antibiotics reversed this effect.
32090575	7	20	gly	glycopeptide	1150:1161	arg2	endogenously intact N-linked and O-linked glycopeptide			endogenously intact N-linked and O-linked glycopeptide						glycopeptide	This is the first study reporting the identification of endogenously intact N-linked and O-linked glycopeptide and is also the largest data set of endogenously intact glycopeptides reported so far.
32090575	7	75	gly	glycopeptides	1219:1231	arg2	endogenously intact glycopeptides			endogenously intact glycopeptides						glycopeptides	This is the first study reporting the identification of endogenously intact N-linked and O-linked glycopeptide and is also the largest data set of endogenously intact glycopeptides reported so far.
33600144	3	20	gly	glycopeptide	513:524	arg2	glycopeptide enrichment			glycopeptide enrichment						glycopeptide	In this work, novel hollow MnFe2O4@C@APBA nanospheres (HMCAs) with magnetic and pH responsiveness were prepared for glycopeptide enrichment.
33421637	8	26	gly	glycoproteins	1737:1749	arg1	SMME-separated glycoproteins	SMME-separated glycoproteins				Fterm		glycoproteins			Furthermore, we successfully developed a fixation method for lectin blotting of SMME-separated glycoproteins and applied to the detection of glycosylation patterns of serum glycoproteins from Fut8+/+ and Fut8-/- mice, also, the method is promising for detecting glycan profiling differences between two samples in both research and clinical settings.
33421637	8	91	gly	glycosylation	1783:1795	arg1	serum glycoproteins	serum glycoproteins				Fterm		glycoproteins			Furthermore, we successfully developed a fixation method for lectin blotting of SMME-separated glycoproteins and applied to the detection of glycosylation patterns of serum glycoproteins from Fut8+/+ and Fut8-/- mice, also, the method is promising for detecting glycan profiling differences between two samples in both research and clinical settings.
33421637	8	95	gly	glycoproteins	1815:1827	arg1	serum glycoproteins	serum glycoproteins				Fterm		glycoproteins			Furthermore, we successfully developed a fixation method for lectin blotting of SMME-separated glycoproteins and applied to the detection of glycosylation patterns of serum glycoproteins from Fut8+/+ and Fut8-/- mice, also, the method is promising for detecting glycan profiling differences between two samples in both research and clinical settings.
32594109	11	7	part_of	Gla	1552:1554	arg1	prothrombin and Gla residues	Gla		prothrombin and Gla residues		OGER	Site	Gla	P06280	residues	CONCLUSIONS Warfarin therapy leads to lower amounts of prothrombin and Gla residues within prothrombin without exerting qualitative and quantitative change in glycan profile and protein synthetic function in the liver.
32594109	11	36	part_of	prothrombin	1536:1546	arg1	prothrombin and Gla residues	prothrombin		prothrombin and Gla residues		PUBTATOR	Site	prothrombin	2147	residues	CONCLUSIONS Warfarin therapy leads to lower amounts of prothrombin and Gla residues within prothrombin without exerting qualitative and quantitative change in glycan profile and protein synthetic function in the liver.
32119847	6	48	gly	glycopeptides	974:986	arg2	glycopeptides			glycopeptides						glycopeptides	Here, we improved the performance of DIA glycoproteomics by using variable width windows optimized for glycopeptides.
33440209	8	35	part_of	ECM	1165:1167	arg1	the composition	ECM		the composition		OGER	Site	ECM	Q13201	position	Further, CRG-AgNps generated ROS in a concentration-dependent manner and modulated the composition of Candida biofilm ECM by increasing the carbohydrate and eDNA content.
32162086	2	7	part_of	PtNPs-GNPs-MWCNTs-β-CD	398:419	arg1	The PtNPs-GNPs-MWCNTs-β-CD nanocomposite	-CD		The PtNPs-GNPs-MWCNTs-β-CD nanocomposite		PUBTATOR	Site	-CD	65057	nanocomposite	The PtNPs-GNPs-MWCNTs-β-CD nanocomposite was easily prepared with an ultrasound-assisted assembly method, and it was characterized by scanning electron microscopy (SEM) and transmission electron microscopy (TEM).
32522274	5	39	part_of	nanophase	1398:1406	arg1	layer-based deposition	nanophase		layer-based deposition		Fterm	Site	nanophase		position	These results indicate that the tunable buffering environment and interaction with the long chains of HA at the molecular level have a critical role in the dependency of the mechanical properties on pH. Due to the pH stability of the ND-OH nanophase, filament-based processing and layer-based deposition at microscale attained enforced mechanical properties of hydrogel.
31999034	7	2	part_of	origin	1358:1363	arg1	the flavanols and proanthocyanidins composition	origin		the flavanols and proanthocyanidins composition		Fterm	Site	origin		position	To establish the relationships between the flavanols and proanthocyanidins composition of rose hip and their origin, principal component analysis was performed on the entire set of liquid chromatography/mass spectrometry data.
32564842	4	35	part_of	TPS/PBAT/HNTs	766:778	arg1	the TPS/PBAT/HNTs biocomposites	HNTs		the TPS/PBAT/HNTs biocomposites		OGER	Site	HNTs	P30990	biocomposites	Elongation at break of the TPS/PBAT/HNTs biocomposites with 5 wt% of HNTs significantly increased with increasing PBAT proportion, i.e., 6.5 %, 41.3 %, and 351.5 % for the composites based on TPS80/PBAT20, TPS50/PBAT50, and TPS20/PBAT80, respectively.
32083322	3	5	part_of	Cel	705:707	arg1	Glu	Cel		Glu		OGER	AminoAcid	Cel	P19835	Glu	Residuals of models obtained from the peaks of GP [0-8 h (GP-8), > 8-24 h (GP-24), > 24-48 h (GP-48) and > 24-81 h (GP-81)] of 0.02, 0.04, 0.08, 0.12 and 0.20 g of glucose (Glu), St and Cel respectively.
33232701	3	13	part_of	CS-PVA	484:489	arg1	The CS-PVA@CuO composite	PVA		The CS-PVA@CuO composite		OGER	Site	PVA	P32926	composite	The CS-PVA@CuO composite was systematically characterized by XRD, FTIR, SEM, and EDX analysis.
33599092	8	33	part_of	IgG	1521:1523	arg1	IgG glycopeptides	IgG		IgG glycopeptides		Cterm	Site	IgG		glycopeptides	CONCLUSIONS AND CLINICAL RELEVANCE Through the simple and high-throughput procedures, this study revealed the important role of IgG glycopeptides in the premature pathology of CRC.
32621318	6	72	part_of	BAL	1047:1049	arg1	cellular composition	BAL		cellular composition		OGER	Site	BAL	Q64285	position	Epicutaneous immunotherapy (EPIT) was performed using fractional infrared laser ablation to generate micropores in the skin, and the effects of LamOVA on blocking IgG, IgE, cellular composition of BAL, lung, and spleen, lung function, and T-cell polarization were assessed.
32324770	1	0	part_of	found	201:205	arg2	insect glycoproteins AND epitopes	insect glycoproteins		epitopes		Fterm	Site	glycoproteins		epitopes	BACKGROUND Cross-reactive carbohydrate determinant (CCD) structures found in plant and insect glycoproteins are commonly recognized by IgE antibodies as epitopes that can lead to extensive cross-reactivity and obscure in vitro diagnostic (IVD) serology results.
32119847	7	81	gly	glycopeptides	1048:1060	arg2	glycopeptides			glycopeptides						glycopeptides	This method allocates narrow windows at m/z ranges rich in glycopeptides, improving analytical specificity and performance.
35515389	10	74	gly	glycoproteins	1724:1736	arg1	salivary glycoproteins	salivary glycoproteins				Fterm		glycoproteins			These results indicated that the glycopattern of LacNAc is increased in salivary glycoproteins from T2DM patients, and an increase in LacNAc-containing N/O-glycans may contribute to this alteration.
33599092	7	21	gly	glycopeptides	1192:1204	arg2	individual glycopeptides			individual glycopeptides						glycopeptides	The changes of glycan features were elucidated by the exploration of individual glycopeptides, showing the biantennary fucosylated glycan without galactose (H3N4F1) or with two galactose (H5N4F1) of IgG1 and IgG2 could distinguish cancer group from both benign and control groups.
33599092	7	34	gly	fucosylated	1231:1241	arg1	the biantennary fucosylated glycan				the biantennary fucosylated glycan						The changes of glycan features were elucidated by the exploration of individual glycopeptides, showing the biantennary fucosylated glycan without galactose (H3N4F1) or with two galactose (H5N4F1) of IgG1 and IgG2 could distinguish cancer group from both benign and control groups.
33787211	6	40	part_of	chitin/PEDOT	1433:1444	arg1	the chitin/PEDOT composite	chitin		the chitin/PEDOT composite		Fterm	Site	chitin		composite	Immunofluorescence, immunohistochemistry, western blotting, and toluidine blue staining analyses on the regenerated sciatic nerve explain that the attachment and proliferation enhancement of Schwann cells and angiogenesis are the vital factors for the chitin/PEDOT composite to facilitate the nerve regeneration.
32162086	4	54	part_of	PtNPs-GNPs-MWCNTs-β-CD	755:776	arg1	PtNPs-GNPs-MWCNTs-β-CD composite	-CD		PtNPs-GNPs-MWCNTs-β-CD composite		PUBTATOR	Site	-CD	65057	composite	Some key experimental parameters such as pH, amount of PtNPs-GNPs-MWCNTs-β-CD composite, and scan rate were optimized.
32861784	2	54	part_of	chitosan-epichlorohydrin/kaolin	459:489	arg1	crosslinked chitosan-epichlorohydrin/kaolin (Chi-ECH/KA) composite	epichlorohydrin		crosslinked chitosan-epichlorohydrin/kaolin (Chi-ECH/KA) composite		Fterm	Site	epichlorohydrin		composite	The final product of crosslinked chitosan-epichlorohydrin/kaolin (Chi-ECH/KA) composite was successfully applied for color removal and chemical oxygen demand (COD) reduction of textile dye namely reactive blue 19 dye (RB19) from aqueous environment.
34552909	10	49	gly	O-glycoprotein	1689:1702	arg1	an O-glycoprotein	an O-glycoprotein				Fterm		O-glycoprotein			Our results reveal that the SARS-CoV-2 S protein is an O-glycoprotein; the O-glycosites and O-glycan compositions vary with the host cell type.
32812835	4	13	gly	afucosylated	678:689	arg1	afucosylated N-glycans				afucosylated N-glycans						However, it is unclear how the composition and levels of afucosylated N-glycans can modulate the biological activities for a recombinant antibody whose target is not a cell surface receptor, as is the case with ADCC.
33600144	6	26	gly	glycoproteins	1301:1313	arg1	210 glycoproteins	210 glycoproteins				Fterm		glycoproteins			In order to verify the application of materials in practice, the HMCAs were used for the analysis of complex samples and it was found that 474 glycopeptides were identified from 210 glycoproteins in three replicate analyses of 2 μL of human serum.
33600144	6	55	gly	glycopeptides	1262:1274	arg2	474 glycopeptides			474 glycopeptides						glycopeptides	In order to verify the application of materials in practice, the HMCAs were used for the analysis of complex samples and it was found that 474 glycopeptides were identified from 210 glycoproteins in three replicate analyses of 2 μL of human serum.
32784105	13	2	part_of	ECM	1774:1776	arg1	ECM composition	ECM		ECM composition		OGER	Site	ECM	Q13201	position	Further studies will be needed to elucidate the influence of ECM composition on EP efficiency.
32384107	6	70	part_of	traits	1471:1476	arg1	composition	traits		composition		OGER	Site	traits	Q96CJ1	position	However, genotype significantly affected the amount of water-soluble arabinoxylan and its composition and thus the heritability of these traits was also significant (0.840 and 0.721).
34364572	7	4	part_of	MHAP/Starch/WST	1044:1058	arg1	MHAP/Starch/WST composite	HAP		MHAP/Starch/WST composite		OGER	Site	HAP		composite	The in-vitro MG-63 osteoblast cells viability, differentiation, and Ca mineralization of MHAP/Starch/WST composite suggests that this new implant will be used for bone regeneration application after careful evaluation of in-vivo and clinical studies.
32135251	10	34	gly	used	1375:1378	arg2	the magnetic alginate/rice husk bio-composite			the magnetic alginate/rice husk bio-composite						bio-composite	The results showed that the magnetic alginate/rice husk bio-composite as low-cost and eco-friendly adsorbent can be effectively used for cationic dye removal steps in the environmental engineering applications.
32507195	2	32	gly	used	378:381	arg2	natural composition			natural composition						position	In this study, natural composition of cellaburate (cellulose-ester) and colophony (pine-resin) was used to prepare films to control ibuprofen release from its amorphous solid dispersion.
33440209	3	62	part_of	enzymes	650:656	arg1	biochemical composition	enzymes		biochemical composition		Fterm	Site	enzymes		position,	In the current study, the anti-biofilm activity of microwave irradiated kappa-carrageenan (CRG) capped AgNps against Candida albicans, and Candida glabrata was investigated in terms of their effect on reactive oxygen species (ROS) generation, cellular morphology, biochemical composition, and the activity of enzymes of extracellular matrix.
32090575	4	8	gly	glycopeptides	705:717	arg2	the endogenously intact glycopeptides			the endogenously intact glycopeptides						glycopeptides	In this platform, the high-temperature acid denaturation, ultrafiltration, and hydrophilic interaction chromatography steps are combined together for the highly efficient extraction of the endogenously intact glycopeptides from a small amount of serum.
32119847	8	87	gly	glycopeptide	1193:1204	arg2	accurate glycopeptide measurement			accurate glycopeptide measurement						glycopeptide	We show that related glycoforms must fall in separate windows to allow accurate glycopeptide measurement.
34364572	3	29	part_of	HAP	491:493	arg1	Wollastonite (WST) clay combined minerals (Mg2+and Gd3+) substituted hydroxyapatite (HAP)/Starch composite	HAP		Wollastonite (WST) clay combined minerals (Mg2+and Gd3+) substituted hydroxyapatite (HAP)/Starch composite		OGER	Site	HAP	O95197	composite	Wollastonite (WST) clay combined minerals (Mg2+and Gd3+) substituted hydroxyapatite (HAP)/Starch composite was prepared using in-situ co-precipitation method.
32512103	0	50	part_of	PVA	69:71	arg1	PVA nanocomposites	PVA		PVA nanocomposites		OGER	Site	PVA	P32926	nanocomposites	Effects of cellulose nanofibrils/graphene oxide hybrid nanofiller in PVA nanocomposites.
33993857	11	39	part_of	FAs	1412:1414	arg1	The composition	FAs		The composition		OGER	Site	FAs	Q63199	position	The composition of individual FAs differed between the groups.
32890396	6	51	gly	N-glycosylation	1193:1207	arg1	known glycan sites				known glycan sites						In order to aid structure-based design and analysis of the spike glycoprotein, CoV3D permits visualization and download of spike structures with modeled N-glycosylation at known glycan sites, and contains structure-based classification of spike conformations, generated by unsupervised clustering.
32090575	1	56	gly	glycopeptides	127:139	arg2	Endogenous glycopeptides			Endogenous glycopeptides						glycopeptides	Endogenous glycopeptides in serum are an invaluable resource for biomarker discovery.
33172991	8	13	part_of	site	1526:1529	arg1	the enzyme	enzyme		site		Fterm	Site	enzyme		site	We propose a simple mechanism to explain this surprising result: free starter units terminate polymerization by displacing the lipid anchor of the growing polymer from its binding site on the enzyme.
33341839	1	58	part_of	hs-CRP	199:204	arg1	dietary composition	CRP		dietary composition		PUBTATOR	Site	CRP	1401	position	OBJECTIVE This study aimed to investigate the association between serum levels of LPS, sCD14 and hs-CRP, and markers of obesity, and dietary composition of healthy adults residing in Jeddah, Saudi Arabia.
34364607	1	20	part_of	PPy/Ag	173:178	arg1	the polypyrrole/silver (PPy/Ag) composite	PPy		the polypyrrole/silver (PPy/Ag) composite		OGER	Site	PPy	P01298	composite	In this research, the polypyrrole/silver (PPy/Ag) composite was first in-situ prepared on alginate fabrics by chemical oxidative polymerization of pyrrole (Py) monomer using silver nitrate as oxidant and sodium dodecyl sulfate (SDS) as the dopant.
33908003	8	54	gly	glycopeptide	1354:1365	arg2	total and unique glycopeptide identifications			total and unique glycopeptide identifications						glycopeptide	Glycopeptide data generated using the SAX-ERLIC enrichment yields a high number of total and unique glycopeptide identifications which can be mapped back to proteins.
34229015	1	9	gly	utilized	385:392	arg2	Chitosan/montmorillonite (CTS/MMT) and chitosan‑gold nanoparticles/montmorillonite (CTS-Au/MMT) composites			Chitosan/montmorillonite (CTS/MMT) and chitosan‑gold nanoparticles/montmorillonite (CTS-Au/MMT) composites						composites	Chitosan/montmorillonite (CTS/MMT) and chitosan‑gold nanoparticles/montmorillonite (CTS-Au/MMT) composites were prepared, characterized through Fourier transformed infrared (FT-IR), X-ray powder diffraction (XRD), and scanning electron microscopy (SEM), and utilized as support for immobilization of polyphenol oxidase (PPO).
32090575	6	59	gly	N-glycopeptides	948:962	arg2	223 intact N-glycopeptides			223 intact N-glycopeptides						N-glycopeptides	In total, 223 intact N-glycopeptides and 51 intact O-glycopeptides are identified from only 40 μL of the human serum sample.
32090575	6	64	gly	O-glycopeptides	978:992	arg2	51 intact O-glycopeptides			51 intact O-glycopeptides						O-glycopeptides	In total, 223 intact N-glycopeptides and 51 intact O-glycopeptides are identified from only 40 μL of the human serum sample.
32090575	3	42	gly	glycopeptides	481:493	arg2	N-linked and O-linked endogenously intact glycopeptides			N-linked and O-linked endogenously intact glycopeptides						glycopeptides	Herein, an integrated platform is fabricated for the identification of N-linked and O-linked endogenously intact glycopeptides.
34965723	3	20	gly	glycopeptide	429:440	arg1	L-lysine			lysine	saccharide-grafted ε-poly					lysine	Herein, we develop a novel ACTIVE glycopeptide of saccharide-grafted ε-poly(L-lysine), that can be credited with adsorption on membrane surfaces, cryopreservation with trehalose, and icephilicity for validity of human erythrocytes.
34965723	3	20	gly	glycopeptide	429:440	arg2	a novel ACTIVE glycopeptide			glycopeptide	saccharide-grafted ε-poly					glycopeptide	Herein, we develop a novel ACTIVE glycopeptide of saccharide-grafted ε-poly(L-lysine), that can be credited with adsorption on membrane surfaces, cryopreservation with trehalose, and icephilicity for validity of human erythrocytes.
33673999	3	53	part_of	XNBR/OST/ZnO	771:782	arg1	XNBR/OST/ZnO composites	OST		XNBR/OST/ZnO composites		OGER	Site	OST		composites	Interestingly, because of the carboxyl groups of OSTs which provided a low pH surroundings to inhibit the growth of bacteria, XNBR/OST/ZnO composites achieved a significant antibacterial activity.
34364607	2	43	part_of	PPy/Ag	491:496	arg1	PPy/Ag composite	PPy		PPy/Ag composite		OGER	Site	PPy	P01298	composite	The effects of mole ratio of Py to silver nitrate, reaction time and dopant concentration on the preparation of PPy/Ag composite were optimized.
33093930	6	1	gly	glycoprotein	1055:1066	arg1	3D glycoprotein structures	3D glycoprotein structures				Fterm		glycoprotein			In the present work, we will describe how the Privateer carbohydrate structure validation software has been extended to harness results from glycomics projects, and its use to greatly improve the validation of 3D glycoprotein structures.
32817557	1	39	gly	O-glycosylated	116:129	arg1	Densely O-glycosylated mucin domains			Densely O-glycosylated mucin domains						domains	Densely O-glycosylated mucin domains are found in a broad range of cell surface and secreted proteins, where they play key physiological roles.
33086113	3	47	part_of	fibroin/calcium	430:444	arg1	Cellulose/silk fibroin/calcium phosphate biocomposite	fibroin		Cellulose/silk fibroin/calcium phosphate biocomposite		Fterm	Site	fibroin		biocomposite	Cellulose/silk fibroin/calcium phosphate biocomposite was investigated by different characterization methods such as FT-IR, XRD, TGA, SEM and EDX.
32764206	0	11	gly	Increase	0:7	arg1	the Lipopolysaccharide Activity	Increase			the Lipopolysaccharide Activity	Fterm		Increase			Increase in the Lipopolysaccharide Activity and Accumulation of Gram-Negative Bacteria in the Stomach With Low Acidity.
34569111	4	34	part_of	receptor	926:933	arg1	the intracellular Toll/Interleukin-1 receptor domain	receptor		the intracellular Toll/Interleukin-1 receptor domain		Fterm	Site	receptor		domain	Our studies give functional and structural insights into the transmembrane domain behavior in different membrane environments, the ectodomain bouncing movement, and the dimerization patterns of the intracellular Toll/Interleukin-1 receptor domain.
34569111	4	37	part_of	Toll/Interleukin-1	907:924	arg1	the intracellular Toll/Interleukin-1 receptor domain	Toll/Interleukin-1		the intracellular Toll/Interleukin-1 receptor domain		Cterm	Site	Toll/Interleukin-1		domain	Our studies give functional and structural insights into the transmembrane domain behavior in different membrane environments, the ectodomain bouncing movement, and the dimerization patterns of the intracellular Toll/Interleukin-1 receptor domain.
32008582	1	88	gly	sialylated	198:207	arg1	a sialylated phosphorylated peptide			a sialylated phosphorylated peptide						peptide	Bovine κ-casein glycomacropeptide (GMP) found in cheese whey is a sialylated phosphorylated peptide which is thought to be a potential ingredient for functional food as well as dietetic food.
32008582	1	88	gly	sialylated	198:207	arg1	Bovine κ-casein glycomacropeptide			Bovine κ-casein glycomacropeptide						glycomacropeptide	Bovine κ-casein glycomacropeptide (GMP) found in cheese whey is a sialylated phosphorylated peptide which is thought to be a potential ingredient for functional food as well as dietetic food.
34156547	3	18	part_of	nanoparticles/vancomycin	461:484	arg1	Chitosan/bioactive glass nanoparticles/vancomycin composites	vancomycin		Chitosan/bioactive glass nanoparticles/vancomycin composites		Fterm	Site	vancomycin		composites	Chitosan/bioactive glass nanoparticles/vancomycin composites were coated on hydrothermally etched titanium substrates by casting method.
33232701	1	38	part_of	CS-PVA	192:197	arg1	A novel, sustainable chitosan polymeric nanocomposite	PVA		A novel, sustainable chitosan polymeric nanocomposite		OGER	Site	PVA	P32926	nanocomposite	A novel, sustainable chitosan polymeric nanocomposite (CS-PVA@CuO) was synthesized and subjected to the removal of acid blue 25 (AB25) from the aqueous environment.
32816991	4	3	part_of	fibronectin	786:796	arg1	three fibronectin type 3 domains	fibronectin		three fibronectin type 3 domains		OGER	Site	fibronectin	P02751	domains	However, TrCel6A and CfCel6B have different cellulose-binding domains (CBDs) and linkers: TrCel6A has a glycosylated peptide linker, whereas CfCel6B's linker consists of three fibronectin type 3 domains.
33080108	14	43	part_of	rhBMP-2/CHA	1835:1845	arg1	The rhBMP-2-loaded CHA (rhBMP-2/CHA) composite	rhBMP-2		The rhBMP-2-loaded CHA (rhBMP-2/CHA) composite		OGER	Site	rhBMP-2	P12643	composite	RESULTS The rhBMP-2-loaded CHA (rhBMP-2/CHA) composite was successfully prepared.
33080108	14	48	part_of	CHA	1830:1832	arg1	The rhBMP-2-loaded CHA (rhBMP-2/CHA) composite	CHA		The rhBMP-2-loaded CHA (rhBMP-2/CHA) composite		OGER	Site	CHA	Q9UL49	composite	RESULTS The rhBMP-2-loaded CHA (rhBMP-2/CHA) composite was successfully prepared.
33080108	14	62	part_of	rhBMP-2-loaded	1815:1828	arg1	The rhBMP-2-loaded CHA (rhBMP-2/CHA) composite	rhBMP-2		The rhBMP-2-loaded CHA (rhBMP-2/CHA) composite		OGER	Site	rhBMP-2	P12643	composite	RESULTS The rhBMP-2-loaded CHA (rhBMP-2/CHA) composite was successfully prepared.
32693125	13	96	gly	used	1405:1408	arg2	These composites			These composites						composites	These composites were used to treat cotton fabric to produce easily applicable and extended-release transdermal patches.
33600144	7	80	gly	glycopeptide	1454:1465	arg2	glycopeptide			glycopeptide						glycopeptide	The results showed that the HMCAs could be used as a promising enrichment material for glycopeptide characterization in MS-based glycoproteomics and related fields.
34601068	4	79	part_of	factors	1000:1006	arg1	ZnO nanocomposites	factors		ZnO nanocomposites		Fterm	Site	factors		nanocomposites	These phenomena were attributed to the released F.MgO:ZnO nanocomposites from chitosan microparticles and paracrine factors from MSCs within the hydrogel, resulting in synergistic biological effects.
32090575	8	0	gly	glycans	1271:1277	arg1	peptides			peptides	peptides		Site			peptides	The distributions of glycans among peptides and proteins and cleavage sites on peptides are further analyzed to seek the regulation of endogenous glycosylation for disease mechanism.
33317218	8	1	part_of	BP/AgP	1480:1485	arg1	the BP/AgP nanocomposite	AgP		the BP/AgP nanocomposite		PUBTATOR	Site	AgP	8319287	nanocomposite	Finally, the antibacterial activity of the BP/AgP nanocomposite was tested using selected bacteria biofilms.
34847186	3	66	gly	non-glycosylated	414:429	arg1	a non-glycosylated protein	a non-glycosylated protein				Fterm		protein			The FDA-approved human tissue plasminogen activator Reteplase (rPA) is a non-glycosylated protein produced in E. coli.
32146511	1	20	part_of	ZnO2/β-CD	179:187	arg1	a biocompatible composite	-CD		a biocompatible composite		PUBTATOR	Site	-CD	65057	composite	The aim of the present study was to evaluate the H2O2 scavenging activity of the ZnO2/β-CD as a biocompatible composite.
33472179	3	11	part_of	protein	590:596	arg1	two peptides	protein		two peptides		Fterm	Site	protein		peptides	In this work, we employed molecular imprinting, using two peptides from the Cas9 protein, to make magnetic peptide-imprinted chitosan nanoparticles.
32553963	5	44	gly	used	745:748	arg2	the prepared nanocomposite			the prepared nanocomposite						nanocomposite	Then the prepared nanocomposite used as superior antibacterial materials with minimum toxicity.
31937642	3	10	gly	core-fucosylated	631:646	arg1	the core-fucosylated structures				the core-fucosylated structures						We have identified in Lactobacillus casei strain BL23 a gene cluster (alf-2) involved in the catabolism of the glycoamino acid fucosyl-α-1,6-N-GlcNAc-Asn (6'FN-Asn), a constituent of the core-fucosylated structures of mammalian N-glycoproteins.
31937642	3	38	gly	N-glycoproteins	672:686	arg1	the core-fucosylated structures	N-glycoproteins			the core-fucosylated structures	Fterm		N-glycoproteins			We have identified in Lactobacillus casei strain BL23 a gene cluster (alf-2) involved in the catabolism of the glycoamino acid fucosyl-α-1,6-N-GlcNAc-Asn (6'FN-Asn), a constituent of the core-fucosylated structures of mammalian N-glycoproteins.
32829815	4	1	part_of	CNC-g-PBAT	678:687	arg1	An in-situ grafting polymerized cellulose nanocrystal (CNC)/PBAT (CNC-g-PBAT) nanocomposite	PBAT (CNC		An in-situ grafting polymerized cellulose nanocrystal (CNC)/PBAT (CNC-g-PBAT) nanocomposite		OGER	Site	PBAT (CNC	P32418	nanocomposite	An in-situ grafting polymerized cellulose nanocrystal (CNC)/PBAT (CNC-g-PBAT) nanocomposite consisting of ungrafted/free PBAT (PBATf) was used as an inclusion directly to reinforce a commercial PBAT.
32829815	4	16	part_of	CNC	667:669	arg1	An in-situ grafting polymerized cellulose nanocrystal (CNC)/PBAT (CNC-g-PBAT) nanocomposite	CNC		An in-situ grafting polymerized cellulose nanocrystal (CNC)/PBAT (CNC-g-PBAT) nanocomposite		OGER	Site	CNC	P32418	nanocomposite	An in-situ grafting polymerized cellulose nanocrystal (CNC)/PBAT (CNC-g-PBAT) nanocomposite consisting of ungrafted/free PBAT (PBATf) was used as an inclusion directly to reinforce a commercial PBAT.
32829815	4	64	part_of	/PBAT	671:675	arg1	An in-situ grafting polymerized cellulose nanocrystal (CNC)/PBAT (CNC-g-PBAT) nanocomposite	PBAT (CNC		An in-situ grafting polymerized cellulose nanocrystal (CNC)/PBAT (CNC-g-PBAT) nanocomposite		OGER	Site	PBAT (CNC	P32418	nanocomposite	An in-situ grafting polymerized cellulose nanocrystal (CNC)/PBAT (CNC-g-PBAT) nanocomposite consisting of ungrafted/free PBAT (PBATf) was used as an inclusion directly to reinforce a commercial PBAT.
33379036	9	28	gly	glycoproteins	2062:2074	arg1	glycoproteins	glycoproteins				Fterm		glycoproteins			The advancement in methods for human milk N-glycoproteins provided by this study represents a key step for better understanding the function of glycoproteins within the breast milk-fed infant.
33379036	9	73	gly	N-glycoproteins	1960:1974	arg1	human milk N-glycoproteins	human milk N-glycoproteins				Fterm		N-glycoproteins			The advancement in methods for human milk N-glycoproteins provided by this study represents a key step for better understanding the function of glycoproteins within the breast milk-fed infant.
33421637	5	37	gly	glycosylation	974:986	arg1	serum proteins	serum proteins				Fterm		proteins			We applied these techniques for the detection of glycosylation patterns of serum proteins from Fut8+/+ and Fut8-/- mice, further analyzed N-linked and O-linked glycans from the separated γ-bands by mass spectrometry, and demonstrated that there are α2,8-sialylated O-glycans contained in mouse sera glycoproteins.
33421637	5	92	gly	α2,8-sialylated	1174:1188	arg1	α2,8-sialylated O-glycans				α2,8-sialylated O-glycans						We applied these techniques for the detection of glycosylation patterns of serum proteins from Fut8+/+ and Fut8-/- mice, further analyzed N-linked and O-linked glycans from the separated γ-bands by mass spectrometry, and demonstrated that there are α2,8-sialylated O-glycans contained in mouse sera glycoproteins.
33421637	5	97	gly	glycoproteins	1224:1236	arg1	mouse sera glycoproteins	mouse sera glycoproteins				Fterm		glycoproteins			We applied these techniques for the detection of glycosylation patterns of serum proteins from Fut8+/+ and Fut8-/- mice, further analyzed N-linked and O-linked glycans from the separated γ-bands by mass spectrometry, and demonstrated that there are α2,8-sialylated O-glycans contained in mouse sera glycoproteins.
33232701	7	54	gly	used	1116:1119	arg2	CS-PVA@CuO polymer nanocomposite			CS-PVA@CuO polymer nanocomposite						nanocomposite	Remarkably, the results reveal the highest adsorption capacity of the CS-PVA@CuO was 171.4 mg/g at 313 K. To be specific, CS-PVA@CuO polymer nanocomposite can be effectively used as a suitable adsorbent material for the potential elimination of anionic AB25 dye from the aqueous solutions.
34965723	8	76	gly	glycopeptide	1551:1562	arg2	the ACTIVE glycopeptide			the ACTIVE glycopeptide						glycopeptide	Therefore, the ACTIVE glycopeptide can be applied as a trehalose-associated "chaperone", providing a new way to serve as a candidate in glycerol-free human erythrocyte cryopreservation.
31972331	0	109	part_of	thyroglobulin	36:48	arg1	the linker domain	thyroglobulin		the linker domain		PUBTATOR	Site	thyroglobulin	P01266	domain	p.L571P in the linker domain of rat thyroglobulin causes intracellular retention.
35515389	5	19	gly	glycoproteins	852:864	arg1	glycoproteins	glycoproteins				Fterm		glycoproteins			Then, lectin-mediated affinity capture of glycoproteins and MALDI-TOF/TOF-MS were performed to obtain the precise structural information of the altered glycans.
33379036	5	63	gly	glycopeptide	996:1007	arg2	tryptic glycopeptide enrichment			tryptic glycopeptide enrichment						glycopeptide	To decrease interference from non-target molecules, we compared techniques for protein extraction, including ethanol (EtOH) precipitation, trichloroacetic acid precipitation, molecular weight cut-off filtration and techniques for tryptic glycopeptide enrichment, including C18-, porous graphitized carbon and hydrophilic interaction liquid chromatography (HILIC)-solid phase extraction (SPE) and acetone precipitation.
33379036	0	19	gly	N-glycoproteins	159:173	arg1	human milk N-glycoproteins	human milk N-glycoproteins				Fterm		N-glycoproteins			Systematic examination of protein extraction, proteolytic glycopeptide enrichment and MS/MS fragmentation techniques for site-specific profiling of human milk N-glycoproteins.
33379036	0	53	gly	glycopeptide	58:69	arg2	proteolytic glycopeptide enrichment			proteolytic glycopeptide enrichment						glycopeptide	Systematic examination of protein extraction, proteolytic glycopeptide enrichment and MS/MS fragmentation techniques for site-specific profiling of human milk N-glycoproteins.
34836688	2	75	part_of	PANI/PVA/SA	338:348	arg1	a millimeter-sized PANI/PVA/SA composite	PVA		a millimeter-sized PANI/PVA/SA composite		OGER	Site	PVA	P32926	composite	In this study, a millimeter-sized PANI/PVA/SA composite (PPS) was synthesized by embedding polyaniline (PANI) into polyvinyl alcohol (PVA)/sodium alginate (SA) gel beads.
32378017	5	70	part_of	protein	834:840	arg1	the activation peptide	protein		the activation peptide		Fterm	Site	protein		peptide	This O-linked site lies N-terminal to the first cleavage site for the activation peptide, an important region of the protein that is removed to activate Factor IX.
32378017	5	70	part_of	protein	834:840	arg1	an important region	protein		an important region		Fterm	Site	protein		region	This O-linked site lies N-terminal to the first cleavage site for the activation peptide, an important region of the protein that is removed to activate Factor IX.
33908003	5	34	gly	glycopeptides	788:800	arg2	glycopeptides			glycopeptides						glycopeptides	Enrichment of glycopeptides from a protein enzymatic digest is an effective approach to overcome such challenges.
33125406	6	16	part_of	factors	1021:1027	arg1	the myosin heavy chain composition	factors		the myosin heavy chain composition		Fterm	Site	factors		position,	We also analyzed the myosin heavy chain composition, protein expression of metabolic enzymes and regulatory factors, and citrate synthase activity.
33125406	6	43	part_of	enzymes	998:1004	arg1	the myosin heavy chain composition	enzymes		the myosin heavy chain composition		Fterm	Site	enzymes		position,	We also analyzed the myosin heavy chain composition, protein expression of metabolic enzymes and regulatory factors, and citrate synthase activity.
32324770	1	0	gly	found	201:205	arg2	insect glycoproteins AND BACKGROUND Cross-reactive carbohydrate determinant (CCD) structures	insect glycoproteins			BACKGROUND Cross-reactive carbohydrate determinant (CCD) structures	Fterm		glycoproteins			BACKGROUND Cross-reactive carbohydrate determinant (CCD) structures found in plant and insect glycoproteins are commonly recognized by IgE antibodies as epitopes that can lead to extensive cross-reactivity and obscure in vitro diagnostic (IVD) serology results.
32324770	1	76	gly	glycoproteins	227:239	arg1	insect glycoproteins	insect glycoproteins				Fterm		glycoproteins			BACKGROUND Cross-reactive carbohydrate determinant (CCD) structures found in plant and insect glycoproteins are commonly recognized by IgE antibodies as epitopes that can lead to extensive cross-reactivity and obscure in vitro diagnostic (IVD) serology results.
34398423	4	28	part_of	D	553:553	arg1	Surfactin and bacillomycin D lipopeptides	bacillomycin D		Surfactin and bacillomycin D lipopeptides		Cterm	Site	bacillomycin D		lipopeptides	Surfactin and bacillomycin D lipopeptides produced by Bacillus amyloliquefaciens B84 strain were loaded onto chitosan nanoparticles by ionotropic gelation process.
32027899	11	45	gly	used	1407:1410	arg2	this functionalized magnetic hybrid composite			this functionalized magnetic hybrid composite						composite	Therefore, this functionalized magnetic hybrid composite might be used to immobilize laccase, an industrially important enzyme.
33527746	8	18	part_of	CU-CDS/PLA/HA/chitosan/rosmarinic	1124:1156	arg1	The biocompatible antibacterial CU-CDS/PLA/HA/chitosan/rosmarinic acid nanocomposite	CDS		The biocompatible antibacterial CU-CDS/PLA/HA/chitosan/rosmarinic acid nanocomposite		OGER	Site	CDS	O35052	nanocomposite	The biocompatible antibacterial CU-CDS/PLA/HA/chitosan/rosmarinic acid nanocomposite is a promising wound healing scaffold which highly accelerates the process of skin regeneration.
32812835	2	26	gly	Afucosylated	264:275	arg1	Afucosylated N-glycans				Afucosylated N-glycans						Afucosylated N-glycans have been shown to significantly alter binding to FcγRIIIa and affect antibody-dependent cell-mediated cytotoxicity (ADCC).
34552909	7	21	gly	O-glycopeptides	1291:1305	arg2	407 intact O-glycopeptides			407 intact O-glycopeptides						O-glycopeptides	In contrast, in the human cell-expressed S protein S1 subunit, 407 intact O-glycopeptides composed of 34 peptides sequences and 30 O-glycosites were discovered by HCD, and 11 O-glycosites were unambiguously assigned by EThcD.
34552909	7	46	gly	O-glycosites	1392:1403	arg2	11 O-glycosites			11 O-glycosites						O-glycosites	In contrast, in the human cell-expressed S protein S1 subunit, 407 intact O-glycopeptides composed of 34 peptides sequences and 30 O-glycosites were discovered by HCD, and 11 O-glycosites were unambiguously assigned by EThcD.
34552909	7	58	gly	O-glycosites	1348:1359	arg2	30 O-glycosites			30 O-glycosites						O-glycosites	In contrast, in the human cell-expressed S protein S1 subunit, 407 intact O-glycopeptides composed of 34 peptides sequences and 30 O-glycosites were discovered by HCD, and 11 O-glycosites were unambiguously assigned by EThcD.
32817557	4	14	part_of	mucin	615:619	arg1	mucin domains	mucin		mucin domains		PUBTATOR	Site	mucin	100508689	domains	Here, we present a panel of bacterial proteases that cleave mucin domains via distinct peptide- and glycan-based motifs, generating a diverse enzymatic toolkit for mucin-selective proteolysis.
34076032	7	39	gly	sialylated	1230:1239	arg1	sialylated glycan				sialylated glycan						Analysis of the mechanism reveals that the sialic acid or sialylated glycan can interact closely with two PyHis molecules stacked together in the assemblies via hydrogen bonding interactions, thereby preventing the ordered accumulation of the gelators.
34906850	4	43	gly	N-glycosylation	925:939	arg1	high mannose-type N-glycans				high mannose-type N-glycans						In vivo imaging revealed that circulation, clearance, and organotropic biodistribution of cancer glyconanosomes in mice depend strongly on cancer cell-type-specific N-glycosylation patterns, the compositions of key glycotypes, particularly dominant abundances of high mannose-type N-glycans and the position-specific sialylation.
34906850	4	64	gly	sialylation	1077:1087	arg1	high mannose-type N-glycans				high mannose-type N-glycans						In vivo imaging revealed that circulation, clearance, and organotropic biodistribution of cancer glyconanosomes in mice depend strongly on cancer cell-type-specific N-glycosylation patterns, the compositions of key glycotypes, particularly dominant abundances of high mannose-type N-glycans and the position-specific sialylation.
32378017	3	2	gly	serine	542:547	arg1	previously undescribed O-linked monosaccharide compositions			serine 141	previously undescribed O-linked monosaccharide compositions					serine 141	Here, we investigated the post-translational modifications of human serum-derived Factor IX and report previously undescribed O-linked monosaccharide compositions at serine 141 and a novel site of glycosylation.
32378017	3	22	gly	glycosylation	573:585	arg2	a novel site			a novel site						site	Here, we investigated the post-translational modifications of human serum-derived Factor IX and report previously undescribed O-linked monosaccharide compositions at serine 141 and a novel site of glycosylation.
33407116	1	106	gly	glycosylated	281:292	arg1	hydroxyproline-rich proteins	hydroxyproline-rich proteins				Fterm		proteins			BACKGROUND Arabinogalactan-proteins (AGPs) are a class of hydroxyproline-rich proteins (HRGPs) that are heavily glycosylated (> 90%) with type II arabinogalactans (AGs).
32564842	2	1	part_of	TPS/PBAT/HNTs	358:370	arg1	TPS/PBAT/HNTs nano-biocomposites	HNTs		TPS/PBAT/HNTs nano-biocomposites		OGER	Site	HNTs	P30990	nano-biocomposites	TPS/PBAT/HNTs nano-biocomposites with different TPS/PBAT weight fractions and HNTs contents were elaborated using a melt blending process, and their morphology and properties were investigated.
34847186	11	33	gly	fucosylated	1746:1756	arg1	α2,6-sialylated and α1,6-core fucosylated N-glycans				α2,6-sialylated and α1,6-core fucosylated N-glycans						Finally, we addressed concerns with the plant-specific glycosylation by modulating rPA-Fc glycosylation towards serum-like structures including α2,6-sialylated and α1,6-core fucosylated N-glycans completely devoid of plant core fucose and xylose residues.
34847186	11	60	gly	α2,6-sialylated	1716:1730	arg1	α2,6-sialylated and α1,6-core fucosylated N-glycans				α2,6-sialylated and α1,6-core fucosylated N-glycans						Finally, we addressed concerns with the plant-specific glycosylation by modulating rPA-Fc glycosylation towards serum-like structures including α2,6-sialylated and α1,6-core fucosylated N-glycans completely devoid of plant core fucose and xylose residues.
33379036	8	75	part_of	glycoproteins	1767:1779	arg1	246 N-glycopeptides	glycoproteins		246 N-glycopeptides		Fterm	Site	glycoproteins		246 N-glycopeptides	This optimized approach significantly increased the number of N-glycopeptides and precursor N-glycoproteins (246 N-glycopeptides from 29 glycoproteins) compared with a more common extraction approach with no protein extraction and C18 clean-up (62 N-glycopeptides from 11 glycoproteins).
33379036	8	94	part_of	glycoproteins	1902:1914	arg1	62 N-glycopeptides	glycoproteins		62 N-glycopeptides		Fterm	Site	glycoproteins		62 N-glycopeptides	This optimized approach significantly increased the number of N-glycopeptides and precursor N-glycoproteins (246 N-glycopeptides from 29 glycoproteins) compared with a more common extraction approach with no protein extraction and C18 clean-up (62 N-glycopeptides from 11 glycoproteins).
32594109	3	49	part_of	Gla	362:364	arg1	γ-carboxyglutamyl (Gla) residues	Gla		γ-carboxyglutamyl (Gla) residues		OGER	Site	Gla	P06280	residues	This decreases the number of γ-carboxyglutamyl (Gla) residues on prothrombin, converting prothrombin into PIVKA-II.
34097961	4	1	part_of	-β-Galp	666:672	arg1	→6)-β-Galp(1 → residues	Galp		→6)-β-Galp(1 → residues		OGER	Site	Galp	Q9UBC7	1 → residues	Structure characterizations indicated that LBP-W contained a main chain consisting of a repeated unit of →6)-β-Galp(1 → residues with branches composed of α-Araf, β-Galp and α-Rhap residues at position C-3.
34097961	4	12	part_of	β-Galp	721:726	arg1	α-Araf, β-Galp and α-Rhap residues	Galp		α-Araf, β-Galp and α-Rhap residues		OGER	AminoAcid	Galp	Q9UBC7	residues at position	Structure characterizations indicated that LBP-W contained a main chain consisting of a repeated unit of →6)-β-Galp(1 → residues with branches composed of α-Araf, β-Galp and α-Rhap residues at position C-3.
34097961	4	36	part_of	α-Araf	713:718	arg1	α-Araf, β-Galp and α-Rhap residues	Araf		α-Araf, β-Galp and α-Rhap residues		OGER	AminoAcid	Araf	P10398	residues at position	Structure characterizations indicated that LBP-W contained a main chain consisting of a repeated unit of →6)-β-Galp(1 → residues with branches composed of α-Araf, β-Galp and α-Rhap residues at position C-3.
34192263	6	21	part_of	trimer	870:875	arg1	the biochemically purified ectodomain	HCoV-NL63 S trimer		the biochemically purified ectodomain		PUBTATOR	Site	HCoV-NL63 S trimer	43740568	ectodomain	It is structurally homologous to that obtained previously from the biochemically purified ectodomain of HCoV-NL63 S trimer, which displays a three-fold symmetric trimer in a single conformation.
34552909	9	3	gly	modified	1536:1543	arg3	Most glycosites AND sialylated O-glycans			Most glycosites	sialylated O-glycans					glycosites	Most glycosites were modified by sialylated O-glycans such as HexNAc(1)Hex (1)NeuAc (1) and HexNAc(1)Hex (1)NeuAc (2).
34552909	9	3	gly	modified	1536:1543	arg3	Most glycosites AND HexNAc(1)Hex (1)NeuAc (1)			Most glycosites	HexNAc(1)Hex (1)NeuAc (1)					glycosites	Most glycosites were modified by sialylated O-glycans such as HexNAc(1)Hex (1)NeuAc (1) and HexNAc(1)Hex (1)NeuAc (2).
34552909	9	3	gly	modified	1536:1543	arg3	Most glycosites AND HexNAc(1)Hex (1)NeuAc (2)			Most glycosites	HexNAc(1)Hex (1)NeuAc (2)					glycosites	Most glycosites were modified by sialylated O-glycans such as HexNAc(1)Hex (1)NeuAc (1) and HexNAc(1)Hex (1)NeuAc (2).
34552909	9	27	gly	glycosites	1520:1529	arg2	Most glycosites			Most glycosites						glycosites	Most glycosites were modified by sialylated O-glycans such as HexNAc(1)Hex (1)NeuAc (1) and HexNAc(1)Hex (1)NeuAc (2).
34552909	9	34	gly	sialylated	1548:1557	arg1	sialylated O-glycans				sialylated O-glycans						Most glycosites were modified by sialylated O-glycans such as HexNAc(1)Hex (1)NeuAc (1) and HexNAc(1)Hex (1)NeuAc (2).
34552909	9	34	gly	sialylated	1548:1557	arg1	HexNAc(1)Hex (1)NeuAc (1)				HexNAc(1)Hex (1)NeuAc (1)						Most glycosites were modified by sialylated O-glycans such as HexNAc(1)Hex (1)NeuAc (1) and HexNAc(1)Hex (1)NeuAc (2).
34552909	9	34	gly	sialylated	1548:1557	arg1	HexNAc(1)Hex (1)NeuAc (2)				HexNAc(1)Hex (1)NeuAc (2)						Most glycosites were modified by sialylated O-glycans such as HexNAc(1)Hex (1)NeuAc (1) and HexNAc(1)Hex (1)NeuAc (2).
32119847	2	76	gly	glycoproteins	384:396	arg1	glycoproteins	glycoproteins				Fterm		glycoproteins			Sequential window acquisition of all theoretical fragment ion spectra mass spectrometry (SWATH) has proven useful as a data independent acquisition (DIA) MS method for analysis of glycoproteins and their glycan modifications.
32490561	5	25	gly	used	627:630	arg2	calcitonin-gene-related peptide			calcitonin-gene-related peptide						peptide	Naringin (NG) and calcitonin-gene-related peptide (CGRP) were used as osteogenic factors in the fabrication of drug-loaded scaffolds.
33428954	1	64	part_of	Alginate-Neusilin	156:172	arg1	Alginate-Neusilin US2 micro-composite	Alginate-Neusilin US2		Alginate-Neusilin US2 micro-composite		PUBTATOR	Site	Alginate-Neusilin US2	7399	micro-composite	The Alginate-Neusilin US2 micro-composite (MC) beads were fabricated and optimized for oral delivery of hesperidin (HES).
33428954	1	69	part_of	US2	174:176	arg1	Alginate-Neusilin US2 micro-composite	Alginate-Neusilin US2		Alginate-Neusilin US2 micro-composite		PUBTATOR	Site	Alginate-Neusilin US2	7399	micro-composite	The Alginate-Neusilin US2 micro-composite (MC) beads were fabricated and optimized for oral delivery of hesperidin (HES).
32311292	2	10	part_of	protein	248:254	arg1	protein composition	protein		protein composition		Fterm	Site	protein		position	To gain a better understanding of fat and protein composition in DHM and assess potential relationships with modifiable milk bank processes.
32171829	6	1	part_of	LCK	1265:1267	arg1	the LCK hybrid composite	LCK		the LCK hybrid composite		OGER	Site	LCK	P06239	composite	Adsorption-desorption experiments revealed that the LCK hybrid composite could be potentially reused with maintaining high adsorption efficiency.
34044032	2	34	part_of	Ch-Sep	292:297	arg1	The Ch-Sep composite	Sep		The Ch-Sep composite		OGER	Site	Sep	O43157	composite	The Ch-Sep composite was prepared as a beads using with two cross-linking agents: tripolyphosphate (TPP) and epichlorohydrin (ECH).
32119847	9	71	gly	glycopeptides	1393:1405	arg2	glycopeptides			glycopeptides						glycopeptides	We demonstrate the utility of the method by comparing the cell wall glycoproteomes of wild-type and N-glycan biosynthesis deficient yeast and showing improved measurement of glycopeptides with different glycan structures.
33272758	3	27	part_of	proteins	355:362	arg1	The composition	proteins		The composition		Fterm	Site	proteins		position	The composition of rice endosperm proteins and the morphologies of proteins and starch granules were determined by SDS-PAGE and confocal microscopy.
33272758	3	44	part_of	proteins	388:395	arg1	The composition	proteins		The composition		Fterm	Site	proteins		position	The composition of rice endosperm proteins and the morphologies of proteins and starch granules were determined by SDS-PAGE and confocal microscopy.
33379036	8	0	gly	glycoproteins	1902:1914	arg1	11 glycoproteins	11 glycoproteins				Fterm		glycoproteins			This optimized approach significantly increased the number of N-glycopeptides and precursor N-glycoproteins (246 N-glycopeptides from 29 glycoproteins) compared with a more common extraction approach with no protein extraction and C18 clean-up (62 N-glycopeptides from 11 glycoproteins).
33379036	8	64	gly	glycoproteins	1767:1779	arg1	29 glycoproteins	29 glycoproteins				Fterm		glycoproteins			This optimized approach significantly increased the number of N-glycopeptides and precursor N-glycoproteins (246 N-glycopeptides from 29 glycoproteins) compared with a more common extraction approach with no protein extraction and C18 clean-up (62 N-glycopeptides from 11 glycoproteins).
33379036	8	79	gly	N-glycopeptides	1692:1706	arg2	N-glycopeptides			N-glycopeptides						N-glycopeptides	This optimized approach significantly increased the number of N-glycopeptides and precursor N-glycoproteins (246 N-glycopeptides from 29 glycoproteins) compared with a more common extraction approach with no protein extraction and C18 clean-up (62 N-glycopeptides from 11 glycoproteins).
33379036	8	95	gly	extraction	1846:1855	arg1	62 N-glycopeptides			62 N-glycopeptides						62 N-glycopeptides	This optimized approach significantly increased the number of N-glycopeptides and precursor N-glycoproteins (246 N-glycopeptides from 29 glycoproteins) compared with a more common extraction approach with no protein extraction and C18 clean-up (62 N-glycopeptides from 11 glycoproteins).
33379036	8	62	gly	N-glycoproteins	1722:1736	arg1	246 N-glycopeptides	N-glycoproteins		246 N-glycopeptides		Fterm		N-glycoproteins		246 N-glycopeptides	This optimized approach significantly increased the number of N-glycopeptides and precursor N-glycoproteins (246 N-glycopeptides from 29 glycoproteins) compared with a more common extraction approach with no protein extraction and C18 clean-up (62 N-glycopeptides from 11 glycoproteins).
33379036	8	29	gly	246 N-glycopeptides	1739:1757	arg2	246 N-glycopeptides	glycoproteins		246 N-glycopeptides		Fterm		glycoproteins		246 N-glycopeptides	This optimized approach significantly increased the number of N-glycopeptides and precursor N-glycoproteins (246 N-glycopeptides from 29 glycoproteins) compared with a more common extraction approach with no protein extraction and C18 clean-up (62 N-glycopeptides from 11 glycoproteins).
33379036	8	109	gly	62 N-glycopeptides	1875:1892	arg1	11 glycoproteins	glycoproteins		62 N-glycopeptides		Fterm		glycoproteins		62 N-glycopeptides	This optimized approach significantly increased the number of N-glycopeptides and precursor N-glycoproteins (246 N-glycopeptides from 29 glycoproteins) compared with a more common extraction approach with no protein extraction and C18 clean-up (62 N-glycopeptides from 11 glycoproteins).
33093930	0	39	gly	glycoprotein	29:40	arg1	glycoprotein 3D structure	glycoprotein 3D structure				Fterm		glycoprotein			Leveraging glycomics data in glycoprotein 3D structure validation with Privateer.
34694067	5	21	part_of	MiR	770:772	arg1	a MiR@TDNs/Li-hep-gel composite	MiR		a MiR@TDNs/Li-hep-gel composite		PUBTATOR	Site	MiR	220972	composite	Finally, the repair effects on challenging bone defect in SAON using a MiR@TDNs/Li-hep-gel composite are assessed in vivo.
32829815	4	52	gly	used	750:753	arg2	An in-situ grafting polymerized cellulose nanocrystal (CNC)/PBAT (CNC-g-PBAT) nanocomposite			An in-situ grafting polymerized cellulose nanocrystal (CNC)/PBAT (CNC-g-PBAT) nanocomposite						nanocomposite	An in-situ grafting polymerized cellulose nanocrystal (CNC)/PBAT (CNC-g-PBAT) nanocomposite consisting of ungrafted/free PBAT (PBATf) was used as an inclusion directly to reinforce a commercial PBAT.
34346569	5	34	part_of	BC/PVA/g-C3	1120:1130	arg1	the BC/PVA/g-C3 N4 /nettles/trachyspermum composite	PVA		the BC/PVA/g-C3 N4 /nettles/trachyspermum composite		OGER	Site	PVA	P32926	composite	Besides, the toxicity, migration, and cell proliferation results of the synthesized materials on NIH 3T3 fibroblasts were evaluated using MTT and scratch assays and showed that the BC/PVA/g-C3 N4 /nettles/trachyspermum composite not only had no toxic effect on cells but also contributed to cell survival, cell migration, and proliferation has done.
32119847	0	25	gly	glycoprotein	77:88	arg1	improved data independent acquisition glycoprotein analysis	improved data independent acquisition glycoprotein analysis				Fterm		glycoprotein			Glycopeptide variable window SWATH for improved data independent acquisition glycoprotein analysis.
32577656	5	8	gly	glycoprotein	865:876	arg1	the spike glycoprotein	the spike glycoprotein				Fterm		glycoprotein			Integrated molecular viewers allow users to visualize structures of the spike glycoprotein, which is the major target of neutralizing antibodies and vaccine design efforts, as well as sets of spike-antibody complexes, spike sequence variability, and known polymorphisms.
32944295	6	14	part_of	epitopes	718:725	arg1	the S1 subunit	subunit		epitopes		Fterm		subunit			In presence of glycan, epitopes on the S1 subunit, that notably contains the receptor binding domain, remain mostly accessible to antibodies while those present on the S2 subunit are predominantly inaccessible.
32944295	6	45	part_of	contains	759:766	arg1	the S1 subunit AND the receptor binding domain	the S1 subunit		the receptor binding domain		Fterm	Site	subunit		domain	In presence of glycan, epitopes on the S1 subunit, that notably contains the receptor binding domain, remain mostly accessible to antibodies while those present on the S2 subunit are predominantly inaccessible.
32213407	4	68	part_of	β-BC	900:903	arg1	ARGs	-BC		ARGs		PUBTATOR	AminoAcid	-BC	10058	ARGs	To evaluate the role of β-BC plays on ARGs in multi-contaminants stressed system, tet W, tet M, sul-1, sul-2, blaTEM, oxa-1, qnr-S, erm-B and intI-1 are identified.
32213407	4	41	part_of	ARGs	914:917	arg1	erm-B	qnr-S, erm		ARGs		OGER	AminoAcid	qnr-S, erm	P41161	ARGs	To evaluate the role of β-BC plays on ARGs in multi-contaminants stressed system, tet W, tet M, sul-1, sul-2, blaTEM, oxa-1, qnr-S, erm-B and intI-1 are identified.
32213407	4	41	part_of	ARGs	914:917	arg1	oxa-1	blaTEM, oxa-1		ARGs		PUBTATOR	AminoAcid	blaTEM, oxa-1	5018	ARGs	To evaluate the role of β-BC plays on ARGs in multi-contaminants stressed system, tet W, tet M, sul-1, sul-2, blaTEM, oxa-1, qnr-S, erm-B and intI-1 are identified.
33600144	2	66	gly	nonglycopeptides	379:394	arg2	nonglycopeptides			nonglycopeptides						nonglycopeptides	Enrichment materials play a key role in this process; they must have an effective sample-screening ability to eliminate the interference of nonglycopeptides.
32829853	0	31	part_of	bi-MOFs/CNF	28:38	arg1	a Co/Fe bi-MOFs/CNF membrane nanocomposite	MOFs/CNF		a Co/Fe bi-MOFs/CNF membrane nanocomposite		PUBTATOR	Site	MOFs/CNF	4868	nanocomposite	Facile synthesis of a Co/Fe bi-MOFs/CNF membrane nanocomposite and its application in the degradation of tetrabromobisphenol A.
34206199	3	29	gly	used	733:736	arg2	bacterial cellulose composites			bacterial cellulose composites						composites	Osmotica large enough to be excluded from plant cell walls and bacterial cellulose composites with other cell wall polysaccharides were used to alter their water content and to demonstrate that the relationship between water potential and degree of hydration of these materials is affected by their composition.
34206199	3	60	gly	composites	680:689	arg1	other cell wall polysaccharides			composites	other cell wall polysaccharides					composites	Osmotica large enough to be excluded from plant cell walls and bacterial cellulose composites with other cell wall polysaccharides were used to alter their water content and to demonstrate that the relationship between water potential and degree of hydration of these materials is affected by their composition.
34801776	6	1	part_of	pectin	1205:1210	arg1	intensified deposition	pectin		intensified deposition		Fterm	Site	pectin		position	Wall thickening was accompanied by intensified deposition of cellulose, xyloglucan, esterified pectin, arabinogalactan protein and extensin.
34801776	6	4	part_of	extensin	1241:1248	arg1	intensified deposition	extensin		intensified deposition		Fterm	Site	extensin		position	Wall thickening was accompanied by intensified deposition of cellulose, xyloglucan, esterified pectin, arabinogalactan protein and extensin.
34801776	6	8	part_of	protein	1229:1235	arg1	intensified deposition	protein		intensified deposition		Fterm	Site	protein		position	Wall thickening was accompanied by intensified deposition of cellulose, xyloglucan, esterified pectin, arabinogalactan protein and extensin.
32535914	4	72	part_of	CCS-AP	590:595	arg1	the CRS-AP and CCS-AP composites	CCS		the CRS-AP and CCS-AP composites		OGER	Site	CCS	O14618	composites	RESULTS Overall, UHP treatment decreased the particle size of the CRS-AP and CCS-AP composites.
34552909	4	52	gly	O-glycosites	681:692	arg2	O-glycosites			O-glycosites						O-glycosites	Following digestion with trypsin and trypsin/Glu-C, and de-N-glycosylation using PNGase F, we determined the GalNAc-type O-glycosylation pattern of S proteins, including O-glycosites and the six most common O-glycans occupying them, via Byonic identification and manual validation.
34552909	4	74	gly	O-glycosylation	632:646	arg1	O-glycosites	S proteins		O-glycosites		Cterm		S proteins	43740568	O-glycosites	Following digestion with trypsin and trypsin/Glu-C, and de-N-glycosylation using PNGase F, we determined the GalNAc-type O-glycosylation pattern of S proteins, including O-glycosites and the six most common O-glycans occupying them, via Byonic identification and manual validation.
34552909	4	74	gly	O-glycosylation	632:646	arg1	the six most common O-glycans	S proteins			the six most common O-glycans	Cterm		S proteins	43740568		Following digestion with trypsin and trypsin/Glu-C, and de-N-glycosylation using PNGase F, we determined the GalNAc-type O-glycosylation pattern of S proteins, including O-glycosites and the six most common O-glycans occupying them, via Byonic identification and manual validation.
34552909	4	74	gly	O-glycosylation	632:646	arg1	the six most common O-glycans			O-glycosites	the six most common O-glycans					O-glycosites	Following digestion with trypsin and trypsin/Glu-C, and de-N-glycosylation using PNGase F, we determined the GalNAc-type O-glycosylation pattern of S proteins, including O-glycosites and the six most common O-glycans occupying them, via Byonic identification and manual validation.
31937642	2	73	gly	N-glycoproteins	282:296	arg1	N-glycoproteins	N-glycoproteins				Fterm		N-glycoproteins			The use of the glycosidic moiety of N-glycoproteins by bacteria has been reported, but the role of N-glycopeptides or glycoamino acids as the substrates for bacterial growth has not been evaluated.
31937642	2	123	gly	N-glycopeptides	345:359	arg2	N-glycopeptides or glycoamino acids			N-glycopeptides or glycoamino acids						N-glycopeptides	The use of the glycosidic moiety of N-glycoproteins by bacteria has been reported, but the role of N-glycopeptides or glycoamino acids as the substrates for bacterial growth has not been evaluated.
32944295	3	33	gly	N-glycosylation	318:332	arg2	all N-glycosylation sites			all N-glycosylation sites						sites	We model the trimeric Spike protein, including flexible loops and all N-glycosylation sites, in order to elucidate accessible epitopes for antibody-based diagnostics, therapeutics and vaccine development.
32817557	0	34	gly	glycoproteins	93:105	arg1	mucin-domain glycoproteins	mucin-domain glycoproteins				Fterm		glycoproteins			An enzymatic toolkit for selective proteolysis, detection, and visualization of mucin-domain glycoproteins.
32634511	7	21	part_of	CHS-ECH/ZL	1484:1493	arg1	CHS-ECH/ZL composite	CHS		CHS-ECH/ZL composite		OGER	Site	CHS	Q99698	composite	Overall, this research introduces CHS-ECH/ZL composite as an eco-friendly zwitterion adsorbent with good applicability towards the two structurally different cationic and anionic dyes from aqueous environment.
34552909	5	6	gly	O-glycosites	870:881	arg2	43 O-glycosites			43 O-glycosites						O-glycosites	Finally, 255 intact O-glycopeptides composed of 50 peptides sequences and 43 O-glycosites were discovered by higher energy collision-induced dissociation (HCD), and three O-glycosites were confidently identified by electron transfer/higher energy collision-induced dissociation (EThcD) in the insect cell-expressed S protein.
34552909	5	23	gly	O-glycosites	964:975	arg2	three O-glycosites			three O-glycosites						O-glycosites	Finally, 255 intact O-glycopeptides composed of 50 peptides sequences and 43 O-glycosites were discovered by higher energy collision-induced dissociation (HCD), and three O-glycosites were confidently identified by electron transfer/higher energy collision-induced dissociation (EThcD) in the insect cell-expressed S protein.
34552909	5	44	gly	O-glycopeptides	813:827	arg2	255 intact O-glycopeptides			255 intact O-glycopeptides						O-glycopeptides	Finally, 255 intact O-glycopeptides composed of 50 peptides sequences and 43 O-glycosites were discovered by higher energy collision-induced dissociation (HCD), and three O-glycosites were confidently identified by electron transfer/higher energy collision-induced dissociation (EThcD) in the insect cell-expressed S protein.
34800523	4	34	part_of	chitosan-CeO2-CdO	405:421	arg1	chitosan-CeO2-CdO nanocomposites	CdO		chitosan-CeO2-CdO nanocomposites		OGER	Site	CdO	Q16878	nanocomposites	Various composition of chitosan-CeO2-CdO nanocomposites were developed using echo-friendly (mechanical mixing) technique.
31972331	16	51	part_of	TG	2323:2324	arg1	the linker domain	TG		the linker domain		Cterm	Site	TG	P01266	domain	In conclusion, our studies identified a novel amino acid residue within the linker domain of TG associated with its conformational maturation and intracellular trafficking.
31972331	6	91	gly	domain	1134:1139	arg1	TG type 1-6 repeat			domain	TG type 1-6 repeat					domain	Sequencing analyses revealed three random mutations, which accidentally emerged during the course of cloning: c.1712T>C [p.L571P] in the linker domain (amino acid positions 360 to 604), c.2027A>G [p.Q676R] in TG type 1-6 repeat and c.2720A>G [p.Q907R] in the TG type 1-7 repeat.
32812835	6	22	gly	fucosylated	1184:1194	arg1	fucosylated glycoforms				fucosylated glycoforms						While either the presence of complex biantennary or high mannose afucosylated glycoforms significantly increased FcγRIIIa binding activity compared to fucosylated glycoforms, they did not similarly increase aggregated Aβ uptake activity mediated by different effector cells.
32812835	6	31	gly	afucosylated	1098:1109	arg1	high mannose afucosylated glycoforms				high mannose afucosylated glycoforms						While either the presence of complex biantennary or high mannose afucosylated glycoforms significantly increased FcγRIIIa binding activity compared to fucosylated glycoforms, they did not similarly increase aggregated Aβ uptake activity mediated by different effector cells.
32812835	6	56	gly	glycoforms	1111:1120	arg1	high mannose afucosylated glycoforms				high mannose afucosylated glycoforms						While either the presence of complex biantennary or high mannose afucosylated glycoforms significantly increased FcγRIIIa binding activity compared to fucosylated glycoforms, they did not similarly increase aggregated Aβ uptake activity mediated by different effector cells.
32812835	5	5	gly	afucosylated	899:910	arg1	enriched afucosylated N-glycan species				enriched afucosylated N-glycan species						The impact of different types and varying levels of enriched afucosylated N-glycan species on the in vitro bioactivities is assessed for an antibody whose target is aggregated amyloid beta (Aβ).
33673999	2	48	part_of	XNBR/OST/ZnO	569:580	arg1	the XNBR/OST/ZnO composites	OST		the XNBR/OST/ZnO composites		OGER	Site	OST		composites	The formation of ionic cross-link networks and "Zinc-carboxylate polymers" in the XNBR/OST/ZnO composites were confirmed by FT-IR, XRD, XPS, SEM-EDS and TEM.
32758606	8	3	gly	used	1390:1393	arg2	the synthesized polymer composite			the synthesized polymer composite						composite	Adsorption-desorption experiments revealed that the synthesized polymer composite could be used for up to four consecutive cycles.
32861784	0	38	part_of	chitosan-epichlorohydrin/kaolin	112:142	arg1	mesoporous chitosan-epichlorohydrin/kaolin clay composite	epichlorohydrin		mesoporous chitosan-epichlorohydrin/kaolin clay composite		Fterm	Site	epichlorohydrin		composite	Statistical optimization and modeling for color removal and COD reduction of reactive blue 19 dye by mesoporous chitosan-epichlorohydrin/kaolin clay composite.
32090575	2	86	gly	glycopeptides	325:337	arg2	endogenously intact glycopeptides			endogenously intact glycopeptides						glycopeptides	Due to the low abundance and the poor fragmentation in tandem mass spectrometry, the identification of endogenously intact glycopeptides still faces many challenges.
34192263	7	8	gly	sites	1049:1053	arg1	different glycan structures			sites	different glycan structures					sites	In addition to previously proposed and observed glycosylation sites, our map shows density at other sites, as well as different glycan structures.
34192263	7	47	gly	glycosylation	997:1009	arg2	observed glycosylation sites			observed glycosylation sites						sites	In addition to previously proposed and observed glycosylation sites, our map shows density at other sites, as well as different glycan structures.
33379036	2	56	gly	glycoproteins	337:349	arg1	human milk glycoproteins	human milk glycoproteins				Fterm		glycoproteins			Increasing understanding of the functional role of human milk glycoproteins within the infant requires toolsets to comprehensively profile their site-specific glycosylation patterns.
32861784	8	61	part_of	multi-function	1549:1562	arg1	Chi-ECH/KA composite	multi		Chi-ECH/KA composite		OGER	Site	multi		composite	This study introduces Chi-ECH/KA composite as an eco-friendly, potential and multi-function composite bio adsorbent for removal of textile dye and COD reduction from aqueous environment.
31972331	1	107	gly	glycosylated	110:121	arg1	a large glycosylated protein	a large glycosylated protein				Fterm		protein			Thyroglobulin (TG), a large glycosylated protein secreted by thyrocytes into the thyroid follicular lumen, plays an essential role in thyroid hormone biosynthesis.
32090575	5	36	gly	glycopeptides	898:910	arg2	N-linked and O-linked endogenous glycopeptides			N-linked and O-linked endogenous glycopeptides						glycopeptides	Additionally, the twin-spectra scheme and in silico deglycosylation strategy were applied for the identification of N-linked and O-linked endogenous glycopeptides, respectively.
32764206	2	36	part_of	GNB	302:304	arg1	composition	GNB		composition		OGER	Site	GNB		position	Therefore, we investigated both the LPS activity and composition of GNB in the gastric fluid (GF) to assess the potential toxicity of them accumulated in the stomach.
32817557	8	56	gly	glycoproteins	1304:1316	arg1	mucin-domain glycoproteins	mucin-domain glycoproteins				Fterm		glycoproteins			We demonstrated that these catalytically inactive point mutants enable robust detection and visualization of mucin-domain glycoproteins by flow cytometry, Western blot, and immunohistochemistry.
31937642	14	74	gly	core-fucosylated	2537:2552	arg1	the core-fucosylated N-glycoproteins	the core-fucosylated N-glycoproteins				Fterm		N-glycoproteins			Here, we have identified in the commensal species Lactobacillus casei a novel metabolic pathway for the utilization of the glycoamino acid fucosyl-α-1,6-N-GlcNAc-Asn, which is present in the core-fucosylated N-glycoproteins from mammalians.
31937642	14	89	gly	N-glycoproteins	2554:2568	arg1	the core-fucosylated N-glycoproteins	N-glycoproteins			the glycoamino acid fucosyl-α-1,6-N-GlcNAc-Asn	Fterm		N-glycoproteins			Here, we have identified in the commensal species Lactobacillus casei a novel metabolic pathway for the utilization of the glycoamino acid fucosyl-α-1,6-N-GlcNAc-Asn, which is present in the core-fucosylated N-glycoproteins from mammalians.
31937642	14	91	gly	present	2522:2528	arg1	the core-fucosylated N-glycoproteins AND the glycoamino acid fucosyl-α-1,6-N-GlcNAc-Asn	N-glycoproteins			the glycoamino acid fucosyl-α-1,6-N-GlcNAc-Asn	Fterm		N-glycoproteins			Here, we have identified in the commensal species Lactobacillus casei a novel metabolic pathway for the utilization of the glycoamino acid fucosyl-α-1,6-N-GlcNAc-Asn, which is present in the core-fucosylated N-glycoproteins from mammalians.
33862078	5	80	part_of	PVA/PLST	969:976	arg1	all PVA/PLST compositions	PVA		all PVA/PLST compositions		OGER	Site	PVA	P32926	positions	The results showed that cotton fabrics displayed higher water absorption (%) than cotton/polyester fabrics for all PVA/PLST compositions and water absorption was found to decrease with increasing the ratio of PVA in the PVA/PLST blends.
33141322	6	7	part_of	BPNSs-G2-β-CD	1290:1302	arg1	Nafion (NF)-stabilized BPNSs-G2-β-CD composite	-CD		Nafion (NF)-stabilized BPNSs-G2-β-CD composite		PUBTATOR	Site	-CD	65057	composite	An interesting phenomenon was that the value of IL-Tyr/ID-Tyr (1.51) in this work was slightly higher than the value of IL-Trp/ID-Trp (1.49) reported in our previous study, where tryptophan (Trp) enantiomers were electrochemically recognized by Nafion (NF)-stabilized BPNSs-G2-β-CD composite.
32847778	9	75	part_of	contains	1215:1222	arg1	a putative cellulase AND a domain	a putative cellulase		a domain		Fterm	Site	cellulase		domain	Over 8900 potential protein-coding genes were identified in the genome including a putative cellulase that contains a domain from the GH5 family of glycoside hydrolases.
34284721	4	67	part_of	1-Mbp	904:908	arg1	450 1-Mbp genomic regions	Mbp		450 1-Mbp genomic regions		PUBTATOR	Site	Mbp	P13727	regions	RESULTS Separate GWAS conducted for each of 895 individual FT-MIR wavenumber phenotypes, identified 450 1-Mbp genomic regions with significant FT-MIR wavenumber QTL, compared to 246 1-Mbp genomic regions with QTL identified for FT-MIR predicted milk composition traits.
34284721	4	73	part_of	1-Mbp	982:986	arg1	246 1-Mbp genomic regions	Mbp		246 1-Mbp genomic regions		PUBTATOR	Site	Mbp	P13727	regions	RESULTS Separate GWAS conducted for each of 895 individual FT-MIR wavenumber phenotypes, identified 450 1-Mbp genomic regions with significant FT-MIR wavenumber QTL, compared to 246 1-Mbp genomic regions with QTL identified for FT-MIR predicted milk composition traits.
32171829	5	53	part_of	LCK	1019:1021	arg1	the LCK hybrid composite	LCK		the LCK hybrid composite		OGER	Site	LCK	P06239	composite	Results also demonstrated that the LCK hybrid composite exhibited extremely high nitrate and phosphate adsorption capacity and stability which followed the mechanisms by ion exchange, complexation and electrostatic interactions.
32756631	4	98	part_of	PVA/PEC	900:906	arg1	PVA/PEC composites	PEC, PVA		PVA/PEC composites		OGER	Site	PEC, PVA	P32926	composites	Thermogravimetric analysis (TGA) indicated that after the introduction of PEC, PVA/PEC composites maintained better thermal stability and char formation ability.
33421637	0	47	gly	glycosylation	6:18	arg1	mouse serum glycoproteins	mouse serum glycoproteins				Fterm		glycoproteins			Rapid glycosylation analysis of mouse serum glycoproteins separated by supported molecular matrix electrophoresis.
33421637	0	100	gly	glycoproteins	44:56	arg1	mouse serum glycoproteins	mouse serum glycoproteins				Fterm		glycoproteins			Rapid glycosylation analysis of mouse serum glycoproteins separated by supported molecular matrix electrophoresis.
32271757	2	57	part_of	CD44	374:377	arg1	lipid raft domains	CD44		lipid raft domains		OGER	Site	CD44	P16070	domains	The process is controlled by two different pathways: On the one hand palmitoylation keeps CD44 in lipid raft domains and disables the linking to the cytoplasmic adaptor, whereas on the other hand, the presence of phosphatidylinositol-4,5-biphosphate (PIP2) lipids accelerates the formation of the CD44-adaptor complex.
34390404	2	43	part_of	gelatin	248:254	arg1	the gelatin:β-TCP ink compositions	gelatin		the gelatin:β-TCP ink compositions		Fterm	Site	gelatin		positions	Binding of the gelatin:β-TCP ink compositions was optimized by adding carboxymethylcellulose (CMC) to maximize the β-TCP content while maintaining printability.
34390404	2	68	part_of	β-TCP	256:260	arg1	the gelatin:β-TCP ink compositions	TCP		the gelatin:β-TCP ink compositions		PUBTATOR	Site	TCP	6690	positions	Binding of the gelatin:β-TCP ink compositions was optimized by adding carboxymethylcellulose (CMC) to maximize the β-TCP content while maintaining printability.
34364648	16	20	gly	used	2438:2441	arg2	some Lys			some Lys						Lys	Our results demonstrate that sdLys supply is important for milk protein when dietary starch is low, and some Lys may be preferentially used for muscle protein synthesis at the expense of milk protein when sdLys is high.
34076032	2	38	gly	sialylated	510:519	arg1	sialylated glycans				sialylated glycans						However, due to the subtle structural differences of sialic acid species and the complicated composition of glycans, the precise recognition of sialylated glycans is difficult.
33232701	7	47	part_of	CS-PVA	1064:1069	arg1	CS-PVA@CuO polymer nanocomposite	PVA		CS-PVA@CuO polymer nanocomposite		OGER	Site	PVA	P32926	nanocomposite	Remarkably, the results reveal the highest adsorption capacity of the CS-PVA@CuO was 171.4 mg/g at 313 K. To be specific, CS-PVA@CuO polymer nanocomposite can be effectively used as a suitable adsorbent material for the potential elimination of anionic AB25 dye from the aqueous solutions.
32410075	3	64	part_of	ECM	496:498	arg1	composition	ECM		composition		OGER	Site	ECM	Q13201	position	Nearly all respiratory pathologies result in changes in the structure and composition of the ECM; however, the impact of these alterations on the mechanical properties of the tissue is not well understood.
33600144	1	1	gly	glycopeptides	152:164	arg2	glycopeptides			glycopeptides						glycopeptides	Enrichment and detection of glycopeptides are an important clinical measure for the diagnosis of complex diseases.
33908003	2	25	gly	glycans	299:305	arg1	proteins	proteins			glycans	Fterm		proteins			The emergence of glycoproteomic technologies to identify and characterize glycans on proteins has the potential to enable a better understanding the role of glycosylation in biology, disease states, and other areas of interest.
35527137	11	86	part_of	ECM	1569:1571	arg1	low ECM deposition	ECM		low ECM deposition		OGER	Site	ECM	Q13201	position	Human MSCs low proliferative rate and low ECM deposition were seen for all constructs; however, lower proliferative rate within the ECM microenvironment highlights controlled self-renewal of MSCs.
34940975	6	52	part_of	pasta	917:921	arg1	The ingredient composition	pasta		The ingredient composition		OGER	Site	pasta	Q9Y2W3	position	The ingredient composition of the optimally formulated pasta, which leads to the best technological and textural properties, was 94.8% durum wheat semolina, 3.7% whole barley flour, and 1.5% inulin.
33600144	4	25	gly	glycopeptides	768:780	arg2	the glycopeptides			the glycopeptides						glycopeptides	The as-prepared composites have a suitable hollow structure and large specific surface area, and the boron hydroxyl group in their cavities can fix or disconnect the hydrophilic groups of the glycopeptides at different pH, so the glycopeptides can be adsorbed or desorbed in a controllable way.
33600144	4	40	gly	glycopeptides	730:742	arg2	the glycopeptides			the glycopeptides						glycopeptides	The as-prepared composites have a suitable hollow structure and large specific surface area, and the boron hydroxyl group in their cavities can fix or disconnect the hydrophilic groups of the glycopeptides at different pH, so the glycopeptides can be adsorbed or desorbed in a controllable way.