doc_id	sent_index	relation_id	relation	trigger	trigger_offset	arg_num	arg_base_np	arg_protein	arg_domain	arg_site	arg_sugar	PSource	SiteSource	NProtein	NID	SiteName	sent_text
33819626	4	3	gly	uptake	885:890	arg1	K. marxianus CCT 7735	CCT			uptake	OGER		CCT			Herein, we aimed to evaluate the effect of 2-PE on cell growth, cell viability, membrane permeability, glucose uptake, metabolism, and morphology in K. marxianus CCT 7735, as well as its adaptive responses.
33793546	3	40	gly	glycosylated	427:438	arg1	four full-length, fully glycosylated and palmitoylated S proteins	four full-length, fully glycosylated and palmitoylated S proteins				PUBTATOR		S proteins	43740568		To identify possible antibody binding sites, we performed multi-microsecond molecular dynamics simulations of a 4.1 million atom system containing a patch of viral membrane with four full-length, fully glycosylated and palmitoylated S proteins.
32612952	9	32	gly	N-GlcNAc	1441:1448	arg1	EGFR	EGFR			N-GlcNAc	PUBTATOR		EGFR	1956		We overexpressed MGAT3 in breast cancer MDA-MB-231 cells, and overexpression of MGAT3 significantly enhanced the bisecting N-GlcNAc on EGFR and suppressed the EGFR/Erk signaling, which further resulted in the reduction of migratory ability, cell proliferation, and clonal formation.
33815445	3	73	gly	glycoproteins	569:581	arg1	helminth glycoproteins	helminth glycoproteins				Fterm		glycoproteins			Recently, pioneering work has shown that helminth glycoproteins can be produced transiently in Nicotiana benthamiana plants while simultaneously mimicking their native helminth N-glycan composition by co-expression of desired glycosyltransferases.
32980603	1	58	gly	used	191:194	arg2	Fe(III)-loaded chitosan (CTS-Fe) composite			Fe(III)-loaded chitosan (CTS-Fe) composite						composite	Fe(III)-loaded chitosan (CTS-Fe) composite was used for the first time to remove and recover phosphorus (P) from waste activated sludge (WAS) via anaerobic digestion (AD).
33789194	3	47	gly	used	542:545	arg2	The as-prepared CTSM@AMPA-Ti4+ composites			The as-prepared CTSM@AMPA-Ti4+ composites						composites	The as-prepared CTSM@AMPA-Ti4+ composites with stable structure, low steric hindrance, and high Ti4+ loading amount were used as a promising adsorbent for enrichment of phosphopeptides.
32817943	7	6	gly	positions	1036:1044	arg1	glycan structures			positions	glycan structures					positions	In addition to previously proposed and observed glycosylation sites, our map shows density at other amino acid positions as well as differences in glycan structures.
32817943	7	29	gly	glycosylation	973:985	arg2	observed glycosylation sites			observed glycosylation sites						sites	In addition to previously proposed and observed glycosylation sites, our map shows density at other amino acid positions as well as differences in glycan structures.
34872407	11	20	gly	glycoproteins	1238:1250	arg1	HM glycoproteins	HM glycoproteins				Fterm		glycoproteins			Another component that shapes the gut microbiota is HM glycoproteins.
32217362	6	27	gly	O-glycopeptides	1035:1049	arg2	O-glycopeptides			O-glycopeptides						O-glycopeptides	We were able to isolate several kinds of O-glycopeptides from lactophorin and κ-casein: six peptide sequences and five kinds of O-glycans.
34486109	2	50	gly	alpha	447:451	arg1	lipopolysaccharide-induced levels	tumor necrosis factor alpha			lipopolysaccharide-induced levels	PUBTATOR		tumor necrosis factor alpha	21926		Electrical stimulation of the ASN resulted in increased levels of splenic acetylcholine, decreased lipopolysaccharide-induced levels of systemic tumor necrosis factor alpha and mitigated clinical symptoms in a mouse model of rheumatoid arthritis.
33342323	3	6	gly	glycosylated	639:650	arg1	GCS	GCS				OGER		GCS	Q16739		In this work, we have approached novel design and development of glycosylated chitosan (GCS) encapsulated mesoporous silica nanoparticles (GCS-MONPs)-based nano-scaffold for sustainable distributions and controlled/supported arrival of stacked RV for targeting sites, which can be activated by either outer ultrasound activating to discharge the payload, foundation on-request and dependable analgesia.
33815445	6	5	gly	glycoprotein	1340:1351	arg1	the model helminth glycoprotein kappa-5	the model helminth glycoprotein kappa-5				Fterm		glycoprotein			We identified HEXO2 and HEXO3 as enzymes responsible for the cleavage of antennary GalNAc residues of N-glycans on the model helminth glycoprotein kappa-5.
33376510	1	26	gly	N-glycosylated	203:216	arg1	Organic cation transporter	Organic cation transporter				PUBTATOR		Organic cation transporter member 2	6582		Organic cation transporter member 2 (OCT2) is an N-glycosylated transporter that has been shown to be closely associated with the transport of antitumor drugs.
34649671	6	40	gly	predominance	927:938	arg1	the composition AND carbohydrates			the composition	carbohydrates					position	The HS present different structural characteristics, with those extracted from VC having a predominance of functionalized C-aliphatics (carbohydrates), low hydrophobicity, and a 90% proportion of cellulose/hemicellulose carbon in the composition.
33406734	4	26	gly	sialylated	708:717	arg1	the sialylated glycan structure Sialyl-Lewis X				the sialylated glycan structure Sialyl-Lewis X						In the present study, we show an increased expression of the sialylated glycan structure Sialyl-Lewis X (SLeX) in the lung epithelium upon M. tuberculosis infection.
32147344	5	25	gly	utilized	1010:1017	arg2	The PPS/rGO composition			The PPS/rGO composition						position	The PPS/rGO composition of 90: 10 (w/w) was selected because of having the highest biocompatibility and utilized in chitosan hydrogel.
33712120	5	44	gly	composition	722:732	arg1	the pectin composition			the pectin composition	the pectin composition		Site			position	The results showed that the pectin composition of their leaves was similar in terms of galacturonic acid, monosaccharide composition, degree of esterification, functional groups, nuclear magnetic resonance spectrum and morphological characteristics.
33169014	5	34	gly	afucosylated	1063:1074	arg1	afucosylated IgG1	afucosylated IgG1				OGER		IgG1	P01857		These results show that disease severity in COVID-19 correlates with the presence of proinflammatory IgG Fc structures, including afucosylated IgG1.
33691185	9	24	gly	used	1554:1557	arg2	SELP-415K GM-0111 compositions			SELP-415K GM-0111 compositions						positions	SELP-415K GM-0111 compositions were then used to provide localized protection from radiation induced tissue damage in a murine model of RIP.
32248230	5	39	gly	fucosylated	1058:1068	arg1	fucosylated and sialylated HMOs	fucosylated and sialylated HMOs				OGER		HMOs	P00540		This approach identified over 100 different glycoforms and showed a wide diversity of milk composition, with a predominance of fucosylated and sialylated HMOs over nonmodified HMOs.
32248230	5	44	gly	sialylated	1074:1083	arg1	fucosylated and sialylated HMOs	fucosylated and sialylated HMOs				OGER		HMOs	P00540		This approach identified over 100 different glycoforms and showed a wide diversity of milk composition, with a predominance of fucosylated and sialylated HMOs over nonmodified HMOs.
33430198	1	106	gly	used	297:300	arg2	Compositions			Compositions						positions	Compositions based on chitosan/β-glycerophosphate hydrogels with highly porous polylactide granules can be used to obtain moldable bone graft materials that have osteoinductive and osteoconductive properties.
34235650	2	22	gly	used	233:236	arg2	the lipid composition			the lipid composition						position	As such the lipid composition is commonly used to characterize mycobacterial strains at the species and type-species levels.
32825916	4	12	gly	used	570:573	arg2	The Fe-hemin-MOFs/CS-rGO composite			The Fe-hemin-MOFs/CS-rGO composite						composite	The Fe-hemin-MOFs/CS-rGO composite was used to construct a novel H2O2 electrochemical sensor.
34578474	2	78	gly	glycopeptides	425:437	arg2	glycopeptides			glycopeptides						glycopeptides	For comprehensive characterization of their extreme structural complexity occurring in >50% of human proteins, time-consuming multi-step enrichment of glycopeptides is required.
31933111	1	28	gly	found	292:296	arg1	PAP AND the lipopolysaccharides	PAP			the lipopolysaccharides	OGER		PAP	P51003		OBJECTIVES To compare the microbial load and composition and to determine the lipopolysaccharides (LPS) and lipoteichoic acid (LTA) concentrations found in primary apical periodontitis (PAP) and post-treatment apical periodontitis (PTAP), correlating these findings with clinical/tomographic features.
34578474	6	38	gly	glycopeptides	1359:1371	arg2	under-explored sialylated glycopeptides			under-explored sialylated glycopeptides						glycopeptides	Using this strategy, we achieved personalized profiles of patients with hepatitis B virus (HBV, n = 3) and hepatocellular carcinoma (HCC, n = 3) at the depth of >3000 glycopeptides, especially for the large-scale identification of under-explored sialylated glycopeptides.
34578474	6	51	gly	glycopeptides	1269:1281	arg2	>3000 glycopeptides			>3000 glycopeptides						glycopeptides	Using this strategy, we achieved personalized profiles of patients with hepatitis B virus (HBV, n = 3) and hepatocellular carcinoma (HCC, n = 3) at the depth of >3000 glycopeptides, especially for the large-scale identification of under-explored sialylated glycopeptides.
34578474	6	89	gly	sialylated	1348:1357	arg1	under-explored sialylated glycopeptides			under-explored sialylated glycopeptides						glycopeptides	Using this strategy, we achieved personalized profiles of patients with hepatitis B virus (HBV, n = 3) and hepatocellular carcinoma (HCC, n = 3) at the depth of >3000 glycopeptides, especially for the large-scale identification of under-explored sialylated glycopeptides.
32793574	7	36	gly	sialylated	1163:1172	arg1	sialylated IgG4	sialylated IgG4				OGER		IgG4	P01861		All subtypes are equally well amenable to targeted glycosylation, except sialylated IgG4 which frequently accumulates substantial fractions of unusual oligo-mannosidic structures.
34791994	2	5	gly	used	330:333	arg2	composite			composite						composite	And the composite prepared from graphene oxide/chitosan, due to its favorable physical and chemical properties, have been used as a drug delivery system.
32475561	1	23	gly	polysaccharides	149:163	arg1	Nanocomposites			Nanocomposites	Nanocomposites		Site			Nanocomposites	Nanocomposites from plant-derived polysaccharides and proteins are green and sustainable materials that can be applied in various food and biomedical fields.
32217362	7	71	gly	O-glycopeptides	1137:1151	arg2	The O-glycopeptides			The O-glycopeptides						O-glycopeptides	The O-glycopeptides were detected and identified by flow injection analysis combined with electrospray ionization mass spectrometry and tandem mass spectrometry using collision-induced dissociation and electron transfer dissociation.
33541662	3	6	gly	position	556:563	arg1	the glucoseamine backbone			position	the glucoseamine backbone					position	13C NMR experiments provided additional information about the position of the deuterons in the glucoseamine backbone.
33529630	2	15	gly	used	483:486	arg2	the synthesised CNF/AgNPs composite			the synthesised CNF/AgNPs composite						composite	In this work, cellulose nanofibril (CNF), a versatile biopolymer was used to support and disperse silver nanoparticles (AgNPs), and the synthesised CNF/AgNPs composite was used to improve the performance of sodium acetate trihydrate (SAT).
33644618	2	43	gly	glycoforms	268:277	arg1	2 different TSH glycoforms	2 different TSH glycoforms				OGER		TSH			The circulating TSH comprises 2 different TSH glycoforms: TSHdi with 2 and TSHtri with 3 N-glycans and methods have developed to determine their contents of anionic monosaccharides (AMS), that is, sialic acid (SA) and sulfonated N-acetylglactosamine (SU) residues.
33644618	2	65	gly	acid	426:429	arg1	residues			residues						residues	The circulating TSH comprises 2 different TSH glycoforms: TSHdi with 2 and TSHtri with 3 N-glycans and methods have developed to determine their contents of anionic monosaccharides (AMS), that is, sialic acid (SA) and sulfonated N-acetylglactosamine (SU) residues.
34314490	2	36	gly	glycoprotein	412:423	arg1	the S-layer glycoprotein	the S-layer glycoprotein				Fterm		glycoprotein			The composition of an N-linked glycan decorating both the S-layer glycoprotein and archaellins offers one such example.
32516910	7	32	gly	sialylated	1167:1176	arg1	sialylated bisecting biantennary glycan				sialylated bisecting biantennary glycan						Only serum core fucosylated, sialylated bisecting biantennary glycan (FA2BG2S2) showed significant differences between any two stages of transplantation (day -3/-7 and day +14; p = 0.0279).
33376510	0	35	gly	transporter	132:142	arg1	N-glycan alteration	organic cation transporter member 2			N-glycan alteration	PUBTATOR		organic cation transporter member 2	6582		Silencing GnT-V reduces oxaliplatin chemosensitivity in human colorectal cancer cells through N-glycan alteration of organic cation transporter member 2.
32516910	3	18	gly	sialoglycoprotein	404:420	arg1	Altered salivary sialoglycoprotein carbohydrates				Altered salivary sialoglycoprotein carbohydrates						Altered salivary sialoglycoprotein carbohydrates are important in the pathologies in the oral cavity including inflammation, infection and neoplasia.
32217362	8	8	gly	used	1423:1426	arg2	O-Glycopeptides			O-Glycopeptides						O-Glycopeptides	O-Glycopeptides bearing a variety of O-glycans could be used as a substrate for endo-α-N-acetyl galactosaminidase, and their various O-glycan structures were useful for the investigation of enzyme activities.
34551196	3	56	gly	used	705:708	arg2	GLY			GLY						GLY	RESULTS In this research, glycidyl methacrylate (GMA) was used as an intermediate and glycine methyl ester (GLY) was used as an organic nitrogen source to modify carboxymethyl cellulose (CMC) to synthesize a pesticide nanocarrier CMC-PGMA-GLY.
34216844	4	51	gly	used	502:505	arg2	The Ag-β-CD composite			The Ag-β-CD composite						composite	The Ag-β-CD composite was used to detect ciprofloxacin by employing differential pulse voltammetry (DPV) and cyclic voltammetry (CV).
33644618	7	75	gly	sialylation	1161:1171	arg1	the glycans				the glycans						Levothyroxin restored sialylation and sulfonation of the glycans already at low free thyroxine (FT4) levels, while degree of N-glycosylation was not restored until the FT4 levels were normal.
34165952	10	137	gly	dextran-borate-glycoprotein	1901:1927	arg1	dextran-borate-glycoprotein	dextran-borate-glycoprotein				Fterm		dextran-borate-glycoprotein			This latter gel took advantage of the dextran-borate-glycoprotein complexation.
34019926	9	43	gly	used	1133:1136	arg2	The developed nano-fiber composites			The developed nano-fiber composites						composites	The developed nano-fiber composites can be potentially used as drug-delivery vehicles due to their efficiency and sustained drug release capacity.
34817202	11	131	gly	glycoprotein	1843:1854	arg1	the native SARS-CoV-2 S glycoprotein	the native SARS-CoV-2 S glycoprotein				PUBTATOR		S glycoprotein	43740568		These findings enhance our understanding of the Golgi processing of the native SARS-CoV-2 S glycoprotein carbohydrates and could assist the design of interventions.
33436218	2	31	gly	attached	523:530	arg3	t-β-D-Glcp AND the O-6 position			the O-6 position	t-β-D-Glcp					position	Structural analyses reveal that SHNP is completely composed of glucose, and its backbone consists of β-D-(1→3)-Glcp with side chains comprising t-β-D-Glcp attached at the O-6 position.
34578474	3	18	gly	glycopeptides	631:643	arg2	glycopeptides			glycopeptides						glycopeptides	Here we report zwitterionic n-dodecylphosphocholine-functionalized magnetic nanoparticles (ZIC-cHILIC@MNPs) as a highly efficient affinity nanoprobe for large-scale enrichment of glycopeptides.
32350116	1	56	gly	glycoproteins	294:306	arg1	various glycoproteins	various glycoproteins				Fterm		glycoproteins			Core fucose is an N-glycan structure synthesized by α1,6-fucosyltransferase 8 (FUT8) localized to the Golgi apparatus and critically regulates the functions of various glycoproteins.
31981661	5	51	gly	used	887:890	arg2	prepared composite			prepared composite						composite	Desorption studies revealed that prepared composite can be used up to three cycles efficiently and thermodynamic parameters such as Gibbs free energy (ΔG0), enthalpy (ΔH0) and entropy (ΔS0) changes showed the adsorption of CR onto [poly (Gg-AAm)/ZVI] was feasible, spontaneous and endothermic.
34299652	2	69	gly	used	393:396	arg2	its composites			its composites						composites	Polylactic acid (PLA) and its composites are currently used for the construction of IMDs.
34817202	3	136	gly	glycoprotein	389:400	arg1	the SARS-CoV-2 S glycoprotein	the SARS-CoV-2 S glycoprotein				PUBTATOR		S glycoprotein	43740568		Approximately 35% of the SARS-CoV-2 S glycoprotein consists of carbohydrate, which can influence virus infectivity and susceptibility to antibody inhibition.
33815445	1	71	gly	glycoproteins	254:266	arg1	immunomodulatory glycoproteins	immunomodulatory glycoproteins				Fterm		glycoproteins			Secretions of parasitic worms (helminths) contain a wide collection of immunomodulatory glycoproteins with the potential to treat inflammatory disorders, like autoimmune diseases.
33376510	7	54	gly	structures	1099:1108	arg1	OCT2	OCT2			structures	PUBTATOR		OCT2	6582		Furthermore, the knockdown of GnT-V caused a marked reduction in the presence of β-1,6-GlcNAc structures on OCT2 and decreased the localization of OCT2 in the cytomembrane, which were associated with a reduced uptake of oxaliplatin in wild-type and oxaliplatin-resistant CW-2 cells.
33169014	3	46	gly	afucosylated	597:608	arg1	afucosylated Fc glycans				afucosylated Fc glycans						Here we show that patients with severe COVID-19 produced a unique serologic signature, including an increased likelihood of IgG1 with afucosylated Fc glycans.
33169014	3	49	gly	IgG1	587:590	arg1	afucosylated Fc glycans	IgG1			afucosylated Fc glycans	OGER		IgG1	P01857		Here we show that patients with severe COVID-19 produced a unique serologic signature, including an increased likelihood of IgG1 with afucosylated Fc glycans.
34141584	1	15	gly	glycosylation	182:194	arg1	proteins	proteins				Fterm		proteins			Congenital disorders of glycosylation (CDG) constitute an ever-growing group of genetic diseases affecting the glycosylation of proteins.
32708305	8	30	gly	glycosylation	1216:1228	arg1	NKp30	NKp30				PUBTATOR		NKp30	259197		Overall, this study provides new insights into the structural basis of NKp30 oligomerization and explains how the stalk region and glycosylation of NKp30 affect its ligand affinity.
33615714	1	22	gly	glycoproteins	255:267	arg1	glycoproteins	glycoproteins				Fterm		glycoproteins			A series of nucleotide sugar interconversion enzymes (NSEs) generate the activated sugar donors required for biosynthesis of cell wall matrix polysaccharides and glycoproteins.
32612952	10	51	gly	N-GlcNAc	1644:1651	arg1	EGFR	EGFR			N-GlcNAc	PUBTATOR		EGFR	1956		Taken together, we conclude that bisecting N-GlcNAc on EGFR inhibits malignant phenotype of breast cancer via down-regulation of EGFR/Erk signaling.
33652073	0	30	gly	enzymes	82:88	arg1	peptidoglycan binding	enzymes			peptidoglycan binding	Fterm		enzymes			Influence of bacterial culture medium on peptidoglycan binding of cell wall lytic enzymes.
32475918	4	8	gly	PSP	529:531	arg1	The monosaccharide components	PSP			The monosaccharide components	OGER		PSP	Q96DR5		The monosaccharide components of PSP were galactose, rhamnose, arabinose, mannose, and glucose at a molar ratio of 11.72 : 1.78 : 4.15 : 1.00 : 2.48.
32475918	4	8	gly	PSP	529:531	arg1	galactose	PSP			galactose	OGER		PSP	Q96DR5		The monosaccharide components of PSP were galactose, rhamnose, arabinose, mannose, and glucose at a molar ratio of 11.72 : 1.78 : 4.15 : 1.00 : 2.48.
33712145	6	1	gly	glycoprotein	969:980	arg1	the spike glycoprotein	the spike glycoprotein				PUBTATOR		spike glycoprotein	43740568		Furthermore, we show that the spike glycoprotein of COVID-19 binds 3.5 times stronger to human lung heparan sulfate than bat lung heparan sulfate.
34817202	6	57	gly	glycoprotein	1033:1044	arg1	the wild-type S glycoprotein N-linked glycans				the wild-type S glycoprotein N-linked glycans						Compared with soluble or solubilized S glycoproteins modified to prevent proteolytic cleavage and to retain a prefusion conformation, more of the wild-type S glycoprotein N-linked glycans are processed to complex forms.
34817202	6	103	gly	glycoproteins	914:926	arg1	soluble or solubilized S glycoproteins	soluble or solubilized S glycoproteins				PUBTATOR		S glycoproteins	43740568		Compared with soluble or solubilized S glycoproteins modified to prevent proteolytic cleavage and to retain a prefusion conformation, more of the wild-type S glycoprotein N-linked glycans are processed to complex forms.
33571209	10	86	gly	cluster	1574:1580	arg1	Dickeya	Dickeya spp			cluster	OGER		Dickeya spp	Q8TCT9		However, comparatively less variation is observed in the putative O-antigen lipopolysaccharide cluster in Dickeya spp.
33644618	10	86	gly	sialylation	1688:1698	arg1	glycans				glycans						During levothyroxine treatment of sPH patients, the sialylation and sulfonation of glycans were restored already at low FT4 levels, while N-glycosylation of TSH was not restored until the FT4 levels were normal.
33644618	10	90	gly	N-glycosylation	1774:1788	arg1	TSH	TSH				OGER		TSH			During levothyroxine treatment of sPH patients, the sialylation and sulfonation of glycans were restored already at low FT4 levels, while N-glycosylation of TSH was not restored until the FT4 levels were normal.
34817202	14	134	gly	glycoprotein	2229:2240	arg1	The SARS-CoV-2 spike glycoprotein	The SARS-CoV-2 spike glycoprotein				PUBTATOR		spike glycoprotein	43740568		The SARS-CoV-2 spike glycoprotein consists of a trimer of two subunits covered with a coat of carbohydrates (sugars).
34955268	10	74	gly	somatotropin	1522:1533	arg1	lower blood glucose	somatotropin			lower blood glucose	PUBTATOR		somatotropin	280804		Feeding LS resulted in lower blood glucose and greater ratio of bovine somatotropin to insulin.
32793574	3	37	gly	variants	473:480	arg1	a comprehensive expression and glycan modulation profiling	variants			a comprehensive expression and glycan modulation profiling	Fterm		variants			Here, we show a comprehensive expression and glycan modulation profiling of IgG variants in planta that are identical in their antigen binding domain but differ in their subclass appearance.
34817202	1	9	gly	glycoprotein	172:183	arg1	its spike (S) glycoprotein	its spike (S) glycoprotein				Fterm		glycoprotein			The SARS-CoV-2 coronavirus, the etiologic agent of COVID-19, uses its spike (S) glycoprotein anchored in the viral membrane to enter host cells.
33139538	2	10	gly	attached	410:417	arg1	its major capsid protein AND the glycans	its major capsid protein			the glycans	Fterm		protein			Unlike many other viruses, PBCV-1 encodes most, if not all, of the enzymes involved in the synthesis of the glycans attached to its major capsid protein.
32475444	5	44	gly	ratio	1198:1202	arg1	lysine			glutamic acid, glycine, lysine, valine						glutamic acid, glycine, lysine, valine	In addition, the CS200 group had higher glutamic acid, glycine, lysine, valine, total nonessential amino acids, total essential amino acids, total amino acids, C22:0, C16:1, C18:1, C20:1, C20:2, C20:5, total monounsaturated fatty acids concentration and polyunsaturated fatty acids (PUFA), and saturated fatty acids (SFA) ratio and lower total SFA, total PUFA concentration, and total n-6:n-3 ratio in breast muscle than the control group (P < 0.05).
33361843	8	93	gly	compositions	1416:1427	arg1	polysaccharides			positions	polysaccharides					positions	At the first stage of the study, the effect of PPS andtheir compositions with polysaccharides on reparative regeneration was studied against the background of its suppression in intact and irradiated animals.
33923867	5	34	gly	fucosylated	720:730	arg1	the fucosylated bi-antennary glycan HexNAc4Hex5Fuc1NeuAc2				the fucosylated bi-antennary glycan HexNAc4Hex5Fuc1NeuAc2						In total, 23 N-glycan compositions were down-regulated in the serum of colon cancer patients, mostly galactosylated forms whilst the mannose-rich HexNAc2Hex7, the fucosylated bi-antennary glycan HexNAc4Hex5Fuc1NeuAc2, and the tetra-antennary HexNAc6Hex7NeuAc3 were up-regulated in serum.
32612952	0	73	gly	N-Acetylglucosamine	10:28	arg1	EGFR	EGFR			N-Acetylglucosamine	PUBTATOR		EGFR	1956		Bisecting N-Acetylglucosamine on EGFR Inhibits Malignant Phenotype of Breast Cancer via Down-Regulation of EGFR/Erk Signaling.
34894199	7	2	gly	Kinase	1068:1073	arg1	the intestine to regulate glucose metabolite status and ageing in mice	Kinase			the intestine to regulate glucose metabolite status and ageing in mice	Fterm		Kinase			It could upregulate the Signal Transducer and Activator of Transcription 3/Forkhead Box O1 (FOXO1)/B cell lymphoma 6 (Bcl-6) pathways in the brain and the c-Jun N-terminal Kinase (JNK)/FOXO1/Bcl-6 signaling axis in the intestine to regulate glucose metabolite status and ageing in mice.
34894199	7	29	gly	Transducer	927:936	arg1	the intestine to regulate glucose metabolite status and ageing in mice	Signal Transducer and Activator of Transcription 3			the intestine to regulate glucose metabolite status and ageing in mice	PUBTATOR		Signal Transducer and Activator of Transcription 3	20848		It could upregulate the Signal Transducer and Activator of Transcription 3/Forkhead Box O1 (FOXO1)/B cell lymphoma 6 (Bcl-6) pathways in the brain and the c-Jun N-terminal Kinase (JNK)/FOXO1/Bcl-6 signaling axis in the intestine to regulate glucose metabolite status and ageing in mice.
34894199	7	33	gly	Activator	942:950	arg1	the intestine to regulate glucose metabolite status and ageing in mice	Signal Transducer and Activator of Transcription 3			the intestine to regulate glucose metabolite status and ageing in mice	PUBTATOR		Signal Transducer and Activator of Transcription 3	20848		It could upregulate the Signal Transducer and Activator of Transcription 3/Forkhead Box O1 (FOXO1)/B cell lymphoma 6 (Bcl-6) pathways in the brain and the c-Jun N-terminal Kinase (JNK)/FOXO1/Bcl-6 signaling axis in the intestine to regulate glucose metabolite status and ageing in mice.
34894199	3	85	gly	dismutase	525:533	arg1	glucose metabolism	dismutase			glucose metabolism	Fterm		dismutase			EPO could significantly improve glucose metabolism and activity of total superoxide dismutase in serum.
32017022	5	48	gly	reactions	1154:1162	arg1	decomposition			decomposition						position	By enabling short residence times (2 min) that are challenging for mixed-vessel types of reactor to establish, the glycosynthase flow reactor succeeds in an effective uncoupling of the LNT II formation (∼80-100 mM/min) from the slower side reactions (decomposition of donor substrate, enzymatic hydrolysis of LNT II) to obtain optimum synthetic efficiency.
34578474	4	19	gly	sialylated	778:787	arg1	sialylated glycopeptide			sialylated glycopeptide						glycopeptide	We demonstrate that ZIC-cHILIC@MNPs possess excellent affinity, with 80-91% specificity for glycopeptide enrichment, especially for sialylated glycopeptide (90%) from biofluid specimens.
34578474	4	48	gly	glycopeptide	738:749	arg2	glycopeptide enrichment			glycopeptide enrichment						glycopeptide	We demonstrate that ZIC-cHILIC@MNPs possess excellent affinity, with 80-91% specificity for glycopeptide enrichment, especially for sialylated glycopeptide (90%) from biofluid specimens.
34578474	4	57	gly	glycopeptide	789:800	arg2	sialylated glycopeptide			sialylated glycopeptide						glycopeptide	We demonstrate that ZIC-cHILIC@MNPs possess excellent affinity, with 80-91% specificity for glycopeptide enrichment, especially for sialylated glycopeptide (90%) from biofluid specimens.
34119424	5	42	gly	N-glycosylation	871:885	arg2	approximately 147 kDa as a dimer and multiple N-glycosylation sites			approximately 147 kDa as a dimer and multiple N-glycosylation sites						sites	However, no recombinant expression system for IgNAR, which has a molecular weight of approximately 147 kDa as a dimer and multiple N-glycosylation sites, has yet been constructed.
33181207	2	24	gly	utilized	373:380	arg2	functionalized seaweed-based composites			functionalized seaweed-based composites						composites	In this work, functionalized seaweed-based composites were successfully prepared and utilized in multiple stages.
32070532	7	36	gly	utilized	1029:1036	arg2	The developed composites			The developed composites						composites	The developed composites may be utilized as excellent supports for enzyme immobilization in industrial application.
33139538	7	47	gly	protein	1408:1414	arg1	the N-glycan	protein			the N-glycan	Fterm		protein			This study, thus, identifies two of the glycosyltransferase activities involved in the synthesis of the N-glycan of the viral major capsid protein in PBCV-1 and establishes that a single protein A064R possesses the three activities needed to synthetize the 2-OMe-α-l-Rha-(1→2)-β-l-Rha fragment.
33785093	0	45	gly	Heparin/Poly-L-Lysine	53:73	arg1	Intercalated Polyurethane Heparin/Poly-L-Lysine Chelates			Lysine	Intercalated Polyurethane Heparin/Poly-L-Lysine Chelates					Lysine	Novel Copper Nanoparticles Intercalated Polyurethane Heparin/Poly-L-Lysine Chelates Coated Stents: Viability Study for Coronary Vascular Cells and Aneurysms Treatments.
32248537	11	32	gly	composition	1586:1596	arg1	important determinants			position	important determinants					position	CONCLUSION Salinity level, variety and cooking method are important determinants of tuber yield and composition.
32612952	7	40	gly	glycoproteins	1056:1068	arg1	the glycoproteins	the glycoproteins				Fterm		glycoproteins			Using PHA-E (a plant lectin recognizing and combining bisecting GlcNAc) based enrichment coupled with nanoLC-MS/MS, we analyzed the glycoproteins bearing bisecting GlcNAc in various breast cancer cells.
34283570	2	84	gly	glycoprotein	380:391	arg1	Lubricin	Lubricin				PUBTATOR		Lubricin	10216		Lubricin (LUB) is an innately biocompatible glycoprotein with impressive antifouling properties.
34283570	2	84	gly	glycoprotein	380:391	arg1	an innately biocompatible glycoprotein	an innately biocompatible glycoprotein				Fterm		glycoprotein			Lubricin (LUB) is an innately biocompatible glycoprotein with impressive antifouling properties.
34817202	7	75	gly	modified	1243:1250	arg3	Asn 234 AND processed glycans			Asn 234	processed glycans			Spike Glycoprotein	43740568	Asn 234	Even Asn 234, a significant percentage of which is decorated by high-mannose glycans on other characterized S trimer preparations, is predominantly modified in the Golgi compartment by processed glycans.
33571209	14	5	gly	heterogeneity	2028:2040	arg1	O-antigen lipopolysaccharides				O-antigen lipopolysaccharides						These multiple HGT processes might have been manifested into the current heterogeneity of O-antigen capsules and O-antigen lipopolysaccharides in Dickeya strains during its evolution.
34817202	2	8	gly	glycoprotein	243:254	arg1	The S glycoprotein	The S glycoprotein				Cterm		S glycoprotein	43740568		The S glycoprotein is the major target for neutralizing antibodies elicited by natural infection and by vaccines.
32217362	4	57	gly	have	614:617	arg1	κ-casein glycomacropeptide AND several O-glycans	lactophorin		glycomacropeptide	several O-glycans	PUBTATOR		lactophorin	282430	glycomacropeptide	In particular, κ-casein glycomacropeptide and lactophorin, which have several O-glycans, are known to exist in whey protein.
33691185	8	5	gly	residues	1432:1439	arg1	the monomer repeats			lysine residues	the monomer repeats					lysine residues	SELP-415K, a SELP analogue with 4 silk units, 15 elastin units, and one elastin unit with lysine residues in the monomer repeats, resulted in the highest rectal bioaccumulation.
34817202	13	12	gly	glycoprotein	2043:2054	arg1	The viral spike glycoprotein	The viral spike glycoprotein				PUBTATOR		spike glycoprotein	43740568		The viral spike glycoprotein is the main target of host neutralizing antibodies that help to control SARS-CoV-2 infection and are important for the protection provided by vaccines.
34817202	5	59	gly	glycoprotein	794:805	arg1	a wild-type SARS-CoV-2 S glycoprotein trimer	a wild-type SARS-CoV-2 S glycoprotein trimer				PUBTATOR		S glycoprotein	43740568		We used a fucose-selective lectin to purify the Golgi-modified fraction of a wild-type SARS-CoV-2 S glycoprotein trimer and determined its glycosylation and disulfide bond profile.
32959246	1	0	gly	glycoproteins	193:205	arg1	glycoproteins	glycoproteins				Fterm		glycoproteins			The outermost surface of bacterial pathogens consists primarily of complex carbohydrate structures-polysaccharides, glycolipids, and glycoproteins.
34578474	7	1	gly	glycopeptides	1453:1465	arg2	sialylated glycopeptides			sialylated glycopeptides						glycopeptides	The glycoproteomics atlas also revealed the differential pattern of sialylated glycopeptides between HBV and HCC groups.
34578474	7	50	gly	sialylated	1442:1451	arg1	sialylated glycopeptides			sialylated glycopeptides						glycopeptides	The glycoproteomics atlas also revealed the differential pattern of sialylated glycopeptides between HBV and HCC groups.
34817202	12	98	gly	glycoprotein	1993:2004	arg1	its spike glycoprotein	its spike glycoprotein				PUBTATOR		spike glycoprotein	43740568		IMPORTANCE The SARS-CoV-2 coronavirus, which causes COVID-19, uses its spike glycoprotein to enter host cells.
34578474	8	40	gly	glycoprotein	1616:1627	arg1	glycoprotein biomarkers	glycoprotein biomarkers				Fterm		glycoprotein			The ZIC-cHILIC@MNPs could be a generic tool for advancing the glycoproteome analysis, and contribute to the screening of glycoprotein biomarkers.
33925509	4	46	gly	CDM	779:781	arg1	glucose	CDM			glucose	OGER		CDM	Q05682		Increased production of the capsule precursor UDP-glucose has been identified by 31P-NMR in CDM with glucose.
32612952	8	72	gly	GlcNAc	1197:1202	arg1	EGFR	EGFR			GlcNAc	PUBTATOR		EGFR	1956		Among the differentially expressed glycoproteins, levels of bisecting GlcNAc on EGFR were significantly decreased in breast cancer cells, confirmed by immunostaining and immunoprecipitation.
32612952	8	78	gly	glycoproteins	1162:1174	arg1	the differentially expressed glycoproteins	the differentially expressed glycoproteins				Fterm		glycoproteins			Among the differentially expressed glycoproteins, levels of bisecting GlcNAc on EGFR were significantly decreased in breast cancer cells, confirmed by immunostaining and immunoprecipitation.
33815445	9	80	gly	glycoproteins	1833:1845	arg1	tailor-made helminth N-glycans	glycoproteins			tailor-made helminth N-glycans	Fterm		glycoproteins			Effective knockout of these enzymes could allow the production of therapeutically relevant glycoproteins with tailor-made helminth N-glycans in plants.
33529630	10	12	gly	used	1466:1469	arg2	This composite			This composite						composite	This composite can therefore be used to fabricate high-performance TES systems with negligible supercooling and improved thermal properties.
34817202	15	56	gly	glycoprotein	2487:2498	arg1	the glycoprotein surface	the glycoprotein surface				Fterm		glycoprotein			Here, we describe the disulfide bonds that assist the SARS-CoV-2 spike glycoprotein to assume the correct shape and the composition of the sugar moieties on the glycoprotein surface.
34817202	15	74	gly	glycoprotein	2397:2408	arg1	the SARS-CoV-2 spike glycoprotein	the SARS-CoV-2 spike glycoprotein				PUBTATOR		spike glycoprotein	43740568		Here, we describe the disulfide bonds that assist the SARS-CoV-2 spike glycoprotein to assume the correct shape and the composition of the sugar moieties on the glycoprotein surface.
32217362	3	67	gly	glycoproteins	449:461	arg1	many glycoproteins	many glycoproteins				Fterm		glycoproteins			The protein composition of bovine milk is well-studied, and many glycoproteins carrying N-glycans and O-glycans have been found in commercial whey protein products.
32217362	3	4	gly	carrying	463:470	arg1	many glycoproteins AND O-glycans	many glycoproteins			O-glycans	Fterm		glycoproteins			The protein composition of bovine milk is well-studied, and many glycoproteins carrying N-glycans and O-glycans have been found in commercial whey protein products.
32217362	3	4	gly	carrying	463:470	arg1	many glycoproteins AND N-glycans	many glycoproteins			N-glycans	Fterm		glycoproteins			The protein composition of bovine milk is well-studied, and many glycoproteins carrying N-glycans and O-glycans have been found in commercial whey protein products.
34677430	2	7	gly	used	462:465	arg2	Electrophoretic deposition			Electrophoretic deposition						position	Electrophoretic deposition (EPD) has several advantages, including its versatility, simplicity, and ability to coat substrates with complex shapes, and is used for the creation of antimicrobial or hydrophobic coatings on metallic biomaterials, among other applications.
32217362	2	48	gly	O-glycopeptides	367:381	arg2	O-glycopeptides			O-glycopeptides						O-glycopeptides	Whey protein products are used as a human dietary supplement and in animal feed and are a readily available resource for the preparation of O-glycopeptides.
33848549	3	10	gly	utilized	395:402	arg2	The resulting composite			The resulting composite						composite	The resulting composite was characterized and utilized as a catalyst for degradation of methylene blue both in dark condition and under visible light irradiation.
32248230	8	2	gly	sialylated	1548:1557	arg1	sialylated and/or fucosylated HMOs	sialylated and/or fucosylated HMOs				OGER		HMOs	P00540		Our ultimate goal is to create a simple, high-throughput method, which can be used for full characterization of sialylated and/or fucosylated HMOs.
32248230	8	75	gly	fucosylated	1566:1576	arg1	sialylated and/or fucosylated HMOs	sialylated and/or fucosylated HMOs				OGER		HMOs	P00540		Our ultimate goal is to create a simple, high-throughput method, which can be used for full characterization of sialylated and/or fucosylated HMOs.
32217362	5	53	gly	O-glycopeptides	713:727	arg2	O-glycopeptides			O-glycopeptides						O-glycopeptides	Here, we report an isolation method of O-glycopeptides bearing disialyl core 1 type and core 2 type glycan moieties from commercially available whey protein products using proteose peptone extraction, enzymatic digestion (with trypsin or thermolysin), and sequential high-performance liquid chromatography purification.
34817202	4	1	gly	glycoproteins	623:635	arg1	spike glycoproteins	spike glycoproteins				PUBTATOR		spike glycoproteins	43740568		We found that virus-like particles produced by coexpression of SARS-CoV-2 S, M, E, and N proteins contained spike glycoproteins that were extensively modified by complex carbohydrates.
34817202	4	123	gly	modified	659:666	arg3	spike glycoproteins AND complex carbohydrates	spike glycoproteins			complex carbohydrates	PUBTATOR		spike glycoproteins	43740568		We found that virus-like particles produced by coexpression of SARS-CoV-2 S, M, E, and N proteins contained spike glycoproteins that were extensively modified by complex carbohydrates.
34500709	14	15	gly	used	1886:1889	arg2	These composites			These composites						composites	These composites can be used for various industrial applications, including packaging.
32248230	7	4	gly	sialylated	1419:1428	arg1	higher molecular weight sialylated HMOs	higher molecular weight sialylated HMOs				OGER		HMOs	P00540		Here we report an easily implemented method developed for the separation, characterization and relative quantitation of large arrays of HMOs, including higher molecular weight sialylated HMOs.
33063290	2	76	gly	Asn-linked	528:537	arg1	(Man)5(GlcNAc)2 Asn-linked glycans			Asn	(Man)5(GlcNAc)2 Asn-linked glycans					Asn	In this study, recombinant human lactoferrin carrying humanized glycosylation (rhLf-h-glycan) expressed in the yeast Pichia pastoris SuperMan5, which is genetically glycoengineered to efficiently produce functional humanized glycoproteins inclosing (Man)5(GlcNAc)2 Asn-linked glycans, was analyzed, inspecting its potential toxicity against cancer cells.
33063290	2	93	gly	glycoproteins	488:500	arg1	functional humanized glycoproteins	functional humanized glycoproteins				Fterm		glycoproteins			In this study, recombinant human lactoferrin carrying humanized glycosylation (rhLf-h-glycan) expressed in the yeast Pichia pastoris SuperMan5, which is genetically glycoengineered to efficiently produce functional humanized glycoproteins inclosing (Man)5(GlcNAc)2 Asn-linked glycans, was analyzed, inspecting its potential toxicity against cancer cells.
33063290	2	85	gly	carrying	308:315	arg1	recombinant human lactoferrin AND rhLf-h-glycan	recombinant human lactoferrin			rhLf-h-glycan	PUBTATOR		lactoferrin	280846		In this study, recombinant human lactoferrin carrying humanized glycosylation (rhLf-h-glycan) expressed in the yeast Pichia pastoris SuperMan5, which is genetically glycoengineered to efficiently produce functional humanized glycoproteins inclosing (Man)5(GlcNAc)2 Asn-linked glycans, was analyzed, inspecting its potential toxicity against cancer cells.
33774369	11	13	gly	N-acetylglucosamine	2074:2092	arg1	the tail region			the tail region	the tail region		Site			region	Compared with controls, SP treated samples displayed: 1) the appearance of bisected di-triantennary complex-type N-glycans (PHA-E), terminating with lactosamine, as well as an increase of O-glycans terminating with Tn and T antigens in both the acrosomal and tail regions; 2) an increase in glycans containing α2,6-linked sialic acid, N-acetylglucosamine, and αgalactose in the tail region.
33774369	11	76	gly	αgalactose	2099:2108	arg1	the tail region			the tail region	the tail region		Site			region	Compared with controls, SP treated samples displayed: 1) the appearance of bisected di-triantennary complex-type N-glycans (PHA-E), terminating with lactosamine, as well as an increase of O-glycans terminating with Tn and T antigens in both the acrosomal and tail regions; 2) an increase in glycans containing α2,6-linked sialic acid, N-acetylglucosamine, and αgalactose in the tail region.
34817202	8	118	gly	glycosylation	1345:1357	arg2	Three incompletely occupied sites			Three incompletely occupied sites						sites	Three incompletely occupied sites of O-linked glycosylation were detected.