doc_id	sent_index	relation_id	relation	trigger	trigger_offset	arg_num	arg_base_np	arg_protein	arg_domain	arg_site	arg_sugar	PSource	SiteSource	NProtein	NID	SiteName	sent_text
31704652	5	43	part_of	Env	965:967	arg1	the Env signal peptide	Env		the Env signal peptide		PUBTATOR	Site	Env	100616444	peptide	Amino acid changes in the Env signal peptide (SP) modulated the Env glycan content, leading to alterations in DC-SIGN-dependent trans-infection and virus sensitivity to antiviral lectins.
31784840	2	71	part_of	chitosan-collagen	425:441	arg1	chitosan-collagen (CS-CG) composite	collagen		chitosan-collagen (CS-CG) composite		PUBTATOR	Site	collagen	1511	composite	This research focused on fabrication and characterization of 3D porous scaffolds using chitosan (CS), collagen (CG) and chitosan-collagen (CS-CG) composite to investigate their influence on human mesenchymal stem cell (hMSC) adhesion, proliferation and differentiation.
31784840	2	81	part_of	CS-CG	444:448	arg1	chitosan-collagen (CS-CG) composite	CS-CG		chitosan-collagen (CS-CG) composite		PUBTATOR	Site	CS-CG	1511	composite	This research focused on fabrication and characterization of 3D porous scaffolds using chitosan (CS), collagen (CG) and chitosan-collagen (CS-CG) composite to investigate their influence on human mesenchymal stem cell (hMSC) adhesion, proliferation and differentiation.
31355147	8	66	gly	sialylated	1617:1626	arg1	sialylated N-glycans				sialylated N-glycans						Among these, six N-glycans were modified with sialic acid or fucose based on LacNAc to form sialylated N-glycans or lewis antigens, respectively.
31099376	11	0	gly	composition	1861:1871	arg1	carbohydrate surfaces			position	carbohydrate surfaces					position	The selection and positioning of sugars within a glycan shield can influence how carbohydrate surfaces of different composition adhere.
30919164	1	6	gly	acids	267:271	arg1	serine			glycine, phenylalanine, and serine						glycine, phenylalanine, and serine	The physical and structural stability of freeze-dried immunoglobulin G (IgG) were examined by applying trehalose and amino acids (glycine, phenylalanine, and serine).
31295525	8	42	part_of	CMCNF-CIP-MMT	1172:1184	arg1	the 3 wt% CMCNF-CIP-MMT composite	CMCNF-CIP		the 3 wt% CMCNF-CIP-MMT composite		OGER	Site	CMCNF-CIP	Q5VWP3	composite	In vitro release experiments revealed that the CIP-MMT composite material provided the sustained release of CIP over 6 h. Erosion of the 3 wt% CMCNF-CIP-MMT composite occurred slowly and provided 48 h of sustained CIP release.
30910957	1	33	part_of	Mucin	111:115	arg1	Mucin domains	Mucin		domains		PUBTATOR	Site	Mucin	100508689	domains	Mucin domains are densely O-glycosylated modular protein domains that are found in a wide variety of cell surface and secreted proteins.
30910957	1	41	part_of	found	185:189	arg2	secreted proteins AND densely O-glycosylated modular protein domains	proteins		domains		Fterm	Site	proteins		domains	Mucin domains are densely O-glycosylated modular protein domains that are found in a wide variety of cell surface and secreted proteins.
30258536	7	16	gly	glycosylated	1931:1942	arg1	aberrantly glycosylated IgG Fc variants	aberrantly glycosylated IgG Fc variants				Fterm		variants			The results suggest that aberrantly glycosylated IgG Fc variants may contribute to the total biological activities of the therapeutic antibodies.
30524110	8	73	part_of	ALG/HAP	1748:1754	arg1	ALG/HAP composites	HAP		ALG/HAP composites		OGER	Site	HAP	O95197	composites	In summary, these results confirm the hypothesis that HAP in ALG hydrogel stimulates chondrocytes to secrete calcified matrix in vitro and in vivo and reveal that ALG/HAP composites have the potential for 3D bioprinting and osteochondral regeneration.
35518704	3	35	gly	glycoproteins	702:714	arg1	therapeutic glycoproteins	therapeutic glycoproteins				Fterm		glycoproteins			In the present study, we genetically manipulated O-glycosylation by disrupting O-mannosyltransferase PMT1 and PMT5 in a low-mannose type N-linked oligosaccharide (Man12GlcNAc2∼Man16GlcNAc2) engineered Pichia pastoris strain to produce therapeutic glycoproteins.
30910957	5	8	gly	glycosite	848:856	arg2	glycosite mapping			glycosite mapping						glycosite	We exploited StcE's unique properties to improve sequence coverage, glycosite mapping, and glycoform analysis of recombinant human mucins by mass spectrometry.
31725254	8	18	part_of	[CEL+EIS	1768:1775	arg1	the [CEL+EIS@SEC] composites	CEL		the [CEL+EIS@SEC] composites		OGER	Site	CEL	P19835	composites	The fact that the DSC curves of the [CEL+EIS@SEC] composites remain the same after going through the heating-melting cycle 220 times clearly indicates that SEC effectively retains EIS in its cavity and protects it from leaking and that the [CEL+EIS@SEC] composites are highly stable and reliable as a phase change material.
31725254	8	65	part_of	[CEL+EIS	1564:1571	arg1	the [CEL+EIS@SEC] composites	CEL		the [CEL+EIS@SEC] composites		OGER	Site	CEL	P19835	composites	The fact that the DSC curves of the [CEL+EIS@SEC] composites remain the same after going through the heating-melting cycle 220 times clearly indicates that SEC effectively retains EIS in its cavity and protects it from leaking and that the [CEL+EIS@SEC] composites are highly stable and reliable as a phase change material.
32228991	2	19	part_of	acid/α-cyclodextrin	508:526	arg1	citric acid/α-cyclodextrin composite	α-cyclodextrin		citric acid/α-cyclodextrin composite		Fterm	Site	α-cyclodextrin		composite	In this work, we synthesized and characterized a series of iron oxide nanoparticles (IONPs) functionalized with different organic molecules (citric acid, α-cyclodextrin, and citric acid/α-cyclodextrin composite).
31028613	11	68	part_of	GPI-anchor	1314:1323	arg1	a putative GPI-anchor sequence	GPI		a putative GPI-anchor sequence		OGER	Site	GPI	P06744	sequence	Closely related BdBGLC2 (Bd2g51280), which has a putative GPI-anchor sequence, was found associated with the plasma membrane and only a truncated version without GPI-anchor complemented the mutant, proving that Brachypodium also has soluble and membrane-bound xyloglucan glucosidases.
30076755	7	60	part_of	HMOS	1024:1027	arg1	HMOS composition	HMOS		HMOS composition		OGER	Site	HMOS	P00540	position	Thereby novel well-defined reference standards for screening HMOS composition by high performance and high throughput analytics are provided.
30997002	2	45	gly	deglycosylated	439:452	arg1	glycan				glycan						Each mAb is examined in three states; glycan intact, truncated (following endoS2 treatment) and fully deglycosylated.
31650194	7	20	part_of	BNC	1071:1073	arg1	BNC composites	BNC		BNC composites		OGER	Site	BNC	Q01954	composites	The results show that BNC composites with distinct performances can be easily designed by simply varying the polymers percentage contents.
30426864	3	49	gly	used	426:429	arg2	calcitonin gene-related peptide			calcitonin gene-related peptide						peptide	Naringin and calcitonin gene-related peptide were used as drugs to prepare drug-loaded scaffolds by direct printing or surface absorption.
30930264	2	38	part_of	atorvastatin	425:436	arg1	atorvastatin drug residue	atorvastatin		atorvastatin drug residue		Fterm	Site	atorvastatin		residue	For this purpose, effective and selective carboxymethylcellulose macromolecule iron composite nanoparticles were synthesized by green methods, characterized and used for uptake of atorvastatin drug residue from water.
31142049	0	26	part_of	Gut	121:123	arg1	Gut Microbiota Composition	Gut		Gut Microbiota Composition		PUBTATOR	Site	Gut	110006	position	Fecal Microbiota Transplantation Controls Murine Chronic Intestinal Inflammation by Modulating Immune Cell Functions and Gut Microbiota Composition.
31276140	3	7	gly	glycosylated	492:503	arg1	glycosylated hemoglobin	glycosylated hemoglobin				Fterm		hemoglobin			The administration of PAS in diabetic mice caused a significant decrease in the glucose level and serum levels of glycosylated hemoglobin (HbA1c).
31349474	7	33	part_of	PLLA/g-MgO/g-CHN	1751:1766	arg1	the developed PLLA/g-MgO/g-CHN composites	CHN		the developed PLLA/g-MgO/g-CHN composites		OGER	Site	CHN	Q92570	composites	Overall, this study demonstrated the addition of g-MgO and g-CHN whiskers together in PLLA matrix played a synergistic promoting role in cell affinity and osteogenic differentiation, and the developed PLLA/g-MgO/g-CHN composites hold great potential in fields of bone repair.
29351237	9	2	gly	O-fucosylated	1124:1136	arg1	Ser60			Ser60						Ser60	Ser60 was found to be O-fucosylated and Ser52 had O-glucose or O-glucose-(xylose)1,2 motifs as glycan variants.
29351237	9	1	gly	had	1148:1150	arg1	Ser52 AND glycan variants			Ser52	glycan variants					Ser52	Ser60 was found to be O-fucosylated and Ser52 had O-glucose or O-glucose-(xylose)1,2 motifs as glycan variants.
29351237	9	1	gly	had	1148:1150	arg1	Ser52 AND xylose			Ser52	xylose					Ser52	Ser60 was found to be O-fucosylated and Ser52 had O-glucose or O-glucose-(xylose)1,2 motifs as glycan variants.
29351237	9	1	gly	had	1148:1150	arg1	Ser52 AND O-glucose-			Ser52	O-glucose-					Ser52	Ser60 was found to be O-fucosylated and Ser52 had O-glucose or O-glucose-(xylose)1,2 motifs as glycan variants.
29351237	9	1	gly	had	1148:1150	arg1	Ser52 AND O-glucose			Ser52	O-glucose					Ser52	Ser60 was found to be O-fucosylated and Ser52 had O-glucose or O-glucose-(xylose)1,2 motifs as glycan variants.
31581071	7	12	gly	glycoprotein	1172:1183	arg1	a test glycoprotein	a test glycoprotein				Fterm		glycoprotein			Carcinoembryonic antigen (CEA), a routinely used marker for colon cancer, was used as a test glycoprotein.
30138539	2	22	part_of	proteins	353:360	arg1	composition	proteins		composition		Fterm	Site	proteins		position	Irrespective of the dialysis modality, hemodialysis (HD) or peritoneal dialysis (PD), the amount and composition of proteins that are removed are important determinants of the biocompatibility of the therapy.
29927098	2	26	part_of	3D	206:207	arg1	a 3D cell/hydrogel composite	a 3D		a 3D cell/hydrogel composite		OGER	Site	a 3D	Q96AK3	composite	A lung organoid is a 3D cell/hydrogel composite that resembles the morphology and cellular composition of the human distal lung.
29578386	8	5	part_of	MET	1246:1248	arg1	INS	INS		MET		OGER	AminoAcid	INS	P01308	MET	More importantly, this system has potential for orderly drug release and well sustained release when MET in the inner and INS in the outer space could be applied as a combination therapy for diabetes.
31472467	0	28	part_of	Fish	0:3	arg1	Fish scale-extracted hydroxyapatite/chitosan composite	Fish		Fish scale-extracted hydroxyapatite/chitosan composite		OGER	Site	Fish	Q5TCZ1	composite	Fish scale-extracted hydroxyapatite/chitosan composite scaffolds fabricated by freeze casting-An innovative strategy for water treatment.
29673061	7	67	gly	contained	1298:1306	arg1	the NP region AND 313.40 ± 50.67 µg/mg glycosaminoglycan			the NP region	313.40 ± 50.67 µg/mg glycosaminoglycan					region	Moreover, the NP region of decellularized IVDs contained 313.40 ± 50.67 µg/mg glycosaminoglycan.
30553356	9	23	gly	used	1385:1388	arg2	modified MMTs-BC nanocomposites			modified MMTs-BC nanocomposites						nanocomposites	These findings demonstrated that modified MMTs-BC nanocomposites could be used as a novel artificial skin substitute for burn patients and scaffold for skin tissue engineering.
31581071	0	59	gly	glycoproteins	155:167	arg1	glycoproteins	glycoproteins				Fterm		glycoproteins			Orthogonal dual molecularly imprinted polymer-based plasmonic immunosandwich assay: A double characteristic recognition strategy for specific detection of glycoproteins.
31687435	4	25	gly	glycoproteins	938:950	arg1	tissue glycoproteins	tissue glycoproteins				Fterm		glycoproteins			An enzyme-linked immunosorbent assay using an anti-α2,6-sialyl LacNAc antibody also supported this result, indicating that dietary carbohydrate restriction results in aberrant glycosylation of tissue glycoproteins.
31687435	4	27	gly	glycosylation	914:926	arg1	tissue glycoproteins	tissue glycoproteins				Fterm		glycoproteins			An enzyme-linked immunosorbent assay using an anti-α2,6-sialyl LacNAc antibody also supported this result, indicating that dietary carbohydrate restriction results in aberrant glycosylation of tissue glycoproteins.
29735037	2	43	part_of	EHF-CS	434:439	arg1	the EHF-CS composite	EHF		the EHF-CS composite		OGER	Site	EHF	Q9NZC4	composite	EGCG-loaded H-2F complex (EHF) was firstly prepared by taking advantages of the reversible self-assembly of the ferritin, and the EHF-CS composite (EHFC) was fabricated by electrostatic interactions with binding number n of (4.1 ± 0.11) and binding constant K of ((5.3 ± 0.2) × 105 M-1), respectively.
31307013	5	37	gly	N347	1021:1024	arg1	an N-glycan			N347	an N-glycan					N347	RESULTS We demonstrate that an N-glycan at N347 within the CBG RCL limits the 9G12 antibody from recognizing its epitope, whereas the 12G2 antibody reactivity is unaffected, thereby contributing to discrepancies in ELISA measurements using these two antibodies.
31142049	3	65	part_of	gut	652:654	arg1	the gut microbiota composition	gut		the gut microbiota composition		PUBTATOR	Site	gut	110006	position	We recently showed that therapeutic effects of FMT during acute experimental colitis are linked to functional modulation of the mucosal immune system and of the gut microbiota composition.
31422531	7	18	part_of	chitosan/ZnO	1044:1055	arg1	chitosan/ZnO NPs composite	chitosan/ZnO NPs		chitosan/ZnO NPs composite		OGER	Site	chitosan/ZnO NPs	P0C0P6	composite	ZnO NPs and chitosan/ZnO NPs composite were synthesized then characterized by transmission electron microscopy (TEM), scanning electron microscopy (SEM), Fourier-transform infrared spectrum (FT-IR), and X-ray diffraction (X-RD).
31422531	7	61	part_of	NPs	1057:1059	arg1	chitosan/ZnO NPs composite	chitosan/ZnO NPs		chitosan/ZnO NPs composite		OGER	Site	chitosan/ZnO NPs	P0C0P6	composite	ZnO NPs and chitosan/ZnO NPs composite were synthesized then characterized by transmission electron microscopy (TEM), scanning electron microscopy (SEM), Fourier-transform infrared spectrum (FT-IR), and X-ray diffraction (X-RD).
29865036	5	24	gly	proteins	801:808	arg1	N-	proteins			N-	Fterm		proteins			METHODS We used Aleuria Aurantia Lectin (AAL)-magnetic particle conjugates to isolate fucosylated glycoproteins in the pooled saliva of healthy volunteers (HV, n= 51) and patients with atrophic gastritis (AG, n= 51) or GC (n= 51), following to release the N- and O-linked glycans from the isolated proteins with PNGase F and NaClO, and further identified the released glycans by MALDI-TOF/TOF-MS, respectively.
29865036	5	24	gly	proteins	801:808	arg1	O-linked glycans	proteins			O-linked glycans	Fterm		proteins			METHODS We used Aleuria Aurantia Lectin (AAL)-magnetic particle conjugates to isolate fucosylated glycoproteins in the pooled saliva of healthy volunteers (HV, n= 51) and patients with atrophic gastritis (AG, n= 51) or GC (n= 51), following to release the N- and O-linked glycans from the isolated proteins with PNGase F and NaClO, and further identified the released glycans by MALDI-TOF/TOF-MS, respectively.
29865036	5	56	gly	fucosylated	589:599	arg1	fucosylated glycoproteins	fucosylated glycoproteins				Fterm		glycoproteins			METHODS We used Aleuria Aurantia Lectin (AAL)-magnetic particle conjugates to isolate fucosylated glycoproteins in the pooled saliva of healthy volunteers (HV, n= 51) and patients with atrophic gastritis (AG, n= 51) or GC (n= 51), following to release the N- and O-linked glycans from the isolated proteins with PNGase F and NaClO, and further identified the released glycans by MALDI-TOF/TOF-MS, respectively.
29865036	5	105	gly	glycoproteins	601:613	arg1	fucosylated glycoproteins	fucosylated glycoproteins				Fterm		glycoproteins			METHODS We used Aleuria Aurantia Lectin (AAL)-magnetic particle conjugates to isolate fucosylated glycoproteins in the pooled saliva of healthy volunteers (HV, n= 51) and patients with atrophic gastritis (AG, n= 51) or GC (n= 51), following to release the N- and O-linked glycans from the isolated proteins with PNGase F and NaClO, and further identified the released glycans by MALDI-TOF/TOF-MS, respectively.
31422531	4	14	part_of	NPs	646:648	arg1	chitosan/ZnO NPs composite	chitosan/ZnO NPs		chitosan/ZnO NPs composite		OGER	Site	chitosan/ZnO NPs	P0C0P6	composite	Thereafter, assess the efficiency of chitosan, zinc oxide nanoparticles (ZnO NPs), and chitosan/ZnO NPs composite against Campylobacter strains to adopt a novel control strategy based on the ability to use those nanocomposites.
31422531	4	66	part_of	chitosan/ZnO	633:644	arg1	chitosan/ZnO NPs composite	chitosan/ZnO NPs		chitosan/ZnO NPs composite		OGER	Site	chitosan/ZnO NPs	P0C0P6	composite	Thereafter, assess the efficiency of chitosan, zinc oxide nanoparticles (ZnO NPs), and chitosan/ZnO NPs composite against Campylobacter strains to adopt a novel control strategy based on the ability to use those nanocomposites.
30328055	6	49	part_of	milk	1353:1356	arg1	mare's milk composition	milk		mare's milk composition		PUBTATOR	Site	milk	100532204	position	We have also found significant effects of horse breed and lactation time-point on gene expression and mare's milk composition.
31581071	3	73	part_of	glycoprotein	487:498	arg1	Epitope	glycoprotein		Epitope		Fterm		glycoprotein			Epitope and glycan are two structure features of a glycoprotein.
30559077	5	14	part_of	residue	1074:1080	arg1	heparin	heparin		residue		Fterm	AminoAcid	heparin		residue in	We characterized the mechanism of sono-Fenton heparin degradation through multiple approaches, including HPLC-SAX, disaccharide composition, FT-IR, NMR and top-down analysis, and found that the uronic acid residue in heparin was the most susceptible site attacked by OH radicals produced in the sono-Fenton process.
31000032	6	9	part_of	CGT	1074:1076	arg1	composition	CGT		composition		OGER	Site	CGT	Q16880	position	The results obtained contribute to gain a better knowledge of the variations, according to origin and processing, in composition and quality of CGT, commodity widely appreciated by the consumers.
34123048	5	0	gly	sialylated	1066:1075	arg1	sialylated glycan linkage isomers				sialylated glycan linkage isomers						Importantly, different "OFF-ON" ratios of the conical nanochannels system allows the precise and sensitive discrimination of sialylated glycan linkage isomers, α2-3 and α2-6 linkage (the corresponding ion conductance increase ratios are 96.2% and 264%, respectively).
31236201	6	2	gly	glycoproteins	989:1001	arg1	an enhanced EV glycoproteins detection	an enhanced EV glycoproteins detection				Fterm		glycoproteins			In addition, ODG and SEC isolation protocols provided an enhanced EV glycoproteins detection.
31725254	7	31	part_of	[CEL+EIS	1450:1457	arg1	[CEL+EIS@SEC] composites	CEL		[CEL+EIS@SEC] composites		OGER	Site	CEL	P19835	composites	The efficiency of latent heat storage and release of [CEL+EIS@SEC] composites was estimated to be around 57% relative to pure EIS.
29420149	4	62	gly	arm	891:893	arg1	leg				leg						Muscle glycogen content using 13C-magnetic resonance spectroscopy, blood hydration status, body composition, and ECW and ICW content of the arm, trunk, and leg using BIS were measured.
30997002	1	48	part_of	Fc-hinge	318:325	arg1	an intact Fc-hinge fragment	Fc-hinge		an intact Fc-hinge fragment		Cterm	Site	Fc-hinge		fragment	To quantify the measurable variations in the structure of a biopharmaceutical product we systematically evaluate three lots of Herceptin®, two mAb standards and an intact Fc-hinge fragment.
30258536	5	62	gly	carrying	1439:1446	arg1	Fc nonapeptide AND a GlcNAc			Fc nonapeptide	a GlcNAc					nonapeptide	Use of a key intermediate, phenyl (2-O-benzyl-4,6-O-benzylidine-β-d-mannopyranosyl)-(1 → 4)-3,6-di-O-benzyl-2-azido-2-deoxy-1-thio-β-d-glucopyranoside, derived from locust bean gum galactomannan, facilitated greatly the synthesis of a bisected nonasaccharide as a stable precursor of oxazoline derivative needed for the enzymatic trans-glycosylation with Fc nonapeptide carrying a GlcNAc at Asn297 residue, while the coupling reaction catalyzed by mutant endo-M-N175Q proceeded very slowly.
31892045	3	11	gly	used	458:461	arg2	The magG@Zn-MOFs composites			The magG@Zn-MOFs composites						composites	The magG@Zn-MOFs composites were used for extraction of acarbose in plasma prior to its quantitative analysis by LC-MS/MS.
31307013	6	4	gly	N-glycosylation	1267:1281	arg1	N238			N238						N238	Qualitative differences in N-glycosylation at N238 also negatively affect the steroid-binding of CBG in the absence of an N-glycan at N347 caused by a T349A substitution.
31016304	9	9	gly	enoxaparin	1451:1460	arg1	the glycan size distribution	enoxaparin			the glycan size distribution	Fterm		enoxaparin			The results showed that the glycan size distribution of an enoxaparin is more related to its production process.
29432186	3	31	gly	N-glycosylation	440:454	arg2	consensus amino acid motifs			consensus amino acid motifs						motifs	However, variable domains may also acquire N-linked glycans, a process conditional on the introduction of consensus amino acid motifs (N-glycosylation sites) during somatic hypermutation.
29432186	3	31	gly	N-glycosylation	440:454	arg2	N-glycosylation sites			N-glycosylation sites						sites	However, variable domains may also acquire N-linked glycans, a process conditional on the introduction of consensus amino acid motifs (N-glycosylation sites) during somatic hypermutation.
29432186	0	42	gly	glycosylation	51:63	arg1	the immunoglobulin variable region			the immunoglobulin variable region						region	Adaptive antibody diversification through N-linked glycosylation of the immunoglobulin variable region.
30933691	7	77	part_of	have	1192:1195	arg1	the HDC NPs AND a constant composition	the HDC NPs		a constant composition		OGER	Site	HDC NPs	P01860	position	Because HDC conjugate holds precise components, the HDC NPs have a constant composition and drug loading content, endowing a precise chemo-photodynamic therapy nanoplatform.
30030075	4	9	gly	used	700:703	arg2	their composites			their composites						composites	The obtained Biodegradable grafted cellulose and their composites were used as adsorbents for the removal of Ca, Mg, Fe, Pb, and Cu ions individually from aqueous solutions.
31347830	3	31	part_of	containing	473:482	arg1	a membrane protein AND two large transmembrane domains	a membrane protein		two large transmembrane domains		Fterm	Site	protein		domains	GFGLSp is a membrane protein containing two large transmembrane domains connected with a hydrophilic cytoplasmic domain.
30339525	2	54	part_of	MWCNTs/SiO2/β-CD	364:379	arg1	The prepared MWCNTs/SiO2/β-CD composites	-CD		The prepared MWCNTs/SiO2/β-CD composites		PUBTATOR	Site	-CD	65057	composites	The prepared MWCNTs/SiO2/β-CD composites were characterized by Fourier transform infrared spectroscopy, X-ray diffraction, scanning electron microscopy and thermogravimetric analysis.
30258536	1	107	gly	attached	126:133	arg1	the IgG Fc domain AND Glycans			the IgG Fc domain	Glycans					domain	Glycans attached to the IgG Fc domain affect strongly biological activities such as antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC) of therapeutic antibodies.
30033262	10	50	part_of	CS	1818:1819	arg1	CS composite	CS		CS composite		PUBTATOR	Site	CS	1431	composite	Taken together, results show that the physical and biological properties, studied here, of CS composite with Zr based bio-ceramic was comparable with CS-nHA composite scaffolds and hence show the prospective of CS-nCZ for future bone tissue engineering applications.
30884009	2	67	gly	used	225:228	arg2	These antibiotic peptides			These antibiotic peptides						peptides	These antibiotic peptides can be used to prevent infections in agriculture and food industry but also to prepare antimicrobial lozenges, creams, and dressings for medical applications.
30968513	6	10	part_of	SBS-CNC	1011:1017	arg1	the SBS-CNC nanocomposite	CNC		the SBS-CNC nanocomposite		OGER	Site	CNC	P32418	nanocomposite	On the other hand, after the transfer of CNC into the toluene solution upon N2 bubbling, styrene-butadiene-styrene (SBS) triblock copolymer can be dissolved for the SBS-CNC nanocomposite.
29865036	6	51	gly	fucosylated	952:962	arg1	fucosylated N-/O-linked glycans				fucosylated N-/O-linked glycans						RESULTS A total of 9/9, 8/11, and 9/9 fucosylated N-/O-linked glycans were annotated in the isolated salivary proteins from HV, AG, and GC, respectively.
31196533	1	33	gly	used	222:225	arg2	A novel magnetic adsorbent genipin-crosslinked chitosan/graphene oxide-SO3H (GC/MGO-SO3H) composite			A novel magnetic adsorbent genipin-crosslinked chitosan/graphene oxide-SO3H (GC/MGO-SO3H) composite						composite	A novel magnetic adsorbent genipin-crosslinked chitosan/graphene oxide-SO3H (GC/MGO-SO3H) composite was prepared and used as adsorbents of environmental pollutant.
30309012	1	69	gly	database	153:160	arg1	sugars	database			sugars	Fterm		database			Due to a lack of a food composition database on starch and sugars, we developed a comprehensive database on starch and seven types of sugars in commonly consumed foods (n = 2222) in Japan.
30524110	4	39	part_of	ALG/HAP	871:877	arg1	ALG/HAP composites	HAP		ALG/HAP composites		OGER	Site	HAP	O95197	composites	To examine the biological performance of ALG/HAP composites, chondrocyte survival and proliferation, extracellular matrix production, and mineralization potential were evaluated in the presence or absence of the HAP phase.
31725254	5	53	part_of	[CEL+EIS	1062:1069	arg1	the [CEL+EIS@SEC] composites	CEL		the [CEL+EIS@SEC] composites		OGER	Site	CEL	P19835	composites	Similar to EIS alone, EIS in the [CEL+EIS@SEC] composites melts when heated and crystallizes when cooled.
31725254	11	78	part_of	[CEL+EIS	2231:2238	arg1	the [CEL+EIS@SEC] composites	CEL		the [CEL+EIS@SEC] composites		OGER	Site	CEL	P19835	composites	These features enable the [CEL+EIS@SEC] composites to be uniquely suited as high performance materials for such uses as dressings to treat burnt wounds, smart textiles for clothing, smart building materials, and energy storage.
29449596	1	57	part_of	elastin-derived	259:273	arg1	elastin-derived peptides	elastin		elastin-derived peptides		PUBTATOR	Site	elastin	2006	peptides	Heparan sulfates (HSs) modulate tissue elasticity in physiopathological conditions by interacting with various matrix constituents as tropoelastin and elastin-derived peptides.
30426864	7	8	part_of	calcitonin	1236:1245	arg1	calcitonin gene-related peptide	calcitonin		calcitonin gene-related peptide		OGER	Site	calcitonin	P01258	peptide	Furthermore, the naringin or calcitonin gene-related peptide co-printed into the scaffold displayed a steady sustained release behaviour for up to 21 days without an initial burst release, while both naringin and calcitonin gene-related peptide absorbed onto the surface of the scaffold were completely released within two days.
30426864	7	57	part_of	calcitonin	1052:1061	arg1	calcitonin gene-related peptide	calcitonin		calcitonin gene-related peptide		OGER	Site	calcitonin	P01258	peptide	Furthermore, the naringin or calcitonin gene-related peptide co-printed into the scaffold displayed a steady sustained release behaviour for up to 21 days without an initial burst release, while both naringin and calcitonin gene-related peptide absorbed onto the surface of the scaffold were completely released within two days.
29673153	3	13	gly	pectin	480:485	arg1	monosaccharide composition	pectin			monosaccharide composition	Fterm		pectin			The monosaccharide composition and rheological properties of the pectin were determined.
29351237	8	8	gly	O-glycopeptide	1080:1093	arg2	two different O-glycopeptide sites			two different O-glycopeptide sites						O-glycopeptide sites	N-Glycopeptide analysis with UHPLC-QTOF-MSE confirmed N-glycosylation sites as well as two different O-glycopeptide sites.
29351237	8	71	gly	N-glycosylation	1033:1047	arg2	N-glycosylation sites			N-glycosylation sites						sites	N-Glycopeptide analysis with UHPLC-QTOF-MSE confirmed N-glycosylation sites as well as two different O-glycopeptide sites.
31905655	4	72	part_of	CuFe2O4/CNC	551:561	arg1	The CuFe2O4/CNC@Ag@ZIF-8 nanocomposite	CuFe2O4/CNC		The CuFe2O4/CNC@Ag@ZIF-8 nanocomposite		OGER	Site	CuFe2O4/CNC	P32418	nanocomposite	The CuFe2O4/CNC@Ag@ZIF-8 nanocomposite was characterized by TEM, FTIR, XRD, N2 adsorption-desorption isotherms, VSM, and XPS.
31803935	3	81	part_of	protein	332:338	arg1	protein composition	protein		protein composition		Fterm	Site	protein		position	Photosynthesis, starch, and protein composition are linked with oxalate synthesis and tuber quality under water scarcity.
31687435	5	44	gly	glycoproteins	993:1005	arg1	hepatic glycoproteins	hepatic glycoproteins				Fterm		glycoproteins			These structural alterations of hepatic glycoproteins were not correlated with the expression levels of glycosyltransferase genes but were correlated with down-regulated expression of the Gale gene, which encodes a rate-limiting enzyme for the synthesis of sugar nucleotide donors for protein glycosylation in the liver.
30977264	5	60	gly	pro-angiogenic	650:663	arg1	a pro-angiogenic glycosaminoglycan			pro	a pro-angiogenic glycosaminoglycan					pro	Membranes were treated in a layer-by-layer approach to develop highly charged electrostatic layer that could bind heparin as a pro-angiogenic glycosaminoglycan.
30729136	6	41	gly	glycosylated	1008:1019	arg2	the same sites	protein		sites		Fterm		protein		sites	Analysis of the N-linked glycans using mass spectrometry revealed that the H1 protein is glycosylated at the same sites as the native HA.
29385801	3	38	gly	sialylated	517:526	arg1	the sialylated milk oligosaccharides				the sialylated milk oligosaccharides						A detailed knowledge of the structures, compositions, and quantities of the sialylated milk oligosaccharides (SMOs) is a prerequisite for understanding their biological roles.
32009786	3	61	gly	used	532:535	arg2	Alg-CS composite			Alg-CS composite						composite	Alg-CS composite was first used to load flurbiprofen (Flu), which is a kind of anti-inflammatory non-steroidal molecule.
31295525	6	30	part_of	CIP-MMT	839:845	arg1	The synthesized CIP-MMT composite	CIP		The synthesized CIP-MMT composite		OGER	Site	CIP	Q5VWP3	composite	The synthesized CIP-MMT composite was fabricated using 1.5, 2, or 3 wt% CMCNF.
30218302	3	35	gly	pectin	473:478	arg1	galacturonic acid content	pectin			galacturonic acid content	Fterm		pectin			Compared with mineral acid-extracted pectin, the yield, molecular weight, galacturonic acid content, and DE of the AA-extracted pectin were higher while neutral sugars were lower.
31320048	4	4	gly	contained	1023:1031	arg1	The extracted low-methoxyl pectin AND arabinose	The extracted low-methoxyl pectin			arabinose	Fterm		pectin			The extracted low-methoxyl pectin (DE = 33.65%) with high lightness contained considerable amounts of uronic acids and neutral monosaccharides (glucose, fucose, arabinose, galactose, rhamnose, and mannose).
31320048	4	4	gly	contained	1023:1031	arg1	The extracted low-methoxyl pectin AND mannose	The extracted low-methoxyl pectin			mannose	Fterm		pectin			The extracted low-methoxyl pectin (DE = 33.65%) with high lightness contained considerable amounts of uronic acids and neutral monosaccharides (glucose, fucose, arabinose, galactose, rhamnose, and mannose).
31320048	4	4	gly	contained	1023:1031	arg1	The extracted low-methoxyl pectin AND neutral monosaccharides	The extracted low-methoxyl pectin			neutral monosaccharides	Fterm		pectin			The extracted low-methoxyl pectin (DE = 33.65%) with high lightness contained considerable amounts of uronic acids and neutral monosaccharides (glucose, fucose, arabinose, galactose, rhamnose, and mannose).
31320048	4	4	gly	contained	1023:1031	arg1	The extracted low-methoxyl pectin AND glucose	The extracted low-methoxyl pectin			glucose	Fterm		pectin			The extracted low-methoxyl pectin (DE = 33.65%) with high lightness contained considerable amounts of uronic acids and neutral monosaccharides (glucose, fucose, arabinose, galactose, rhamnose, and mannose).
31320048	4	4	gly	contained	1023:1031	arg1	The extracted low-methoxyl pectin AND galactose	The extracted low-methoxyl pectin			galactose	Fterm		pectin			The extracted low-methoxyl pectin (DE = 33.65%) with high lightness contained considerable amounts of uronic acids and neutral monosaccharides (glucose, fucose, arabinose, galactose, rhamnose, and mannose).
31320048	4	4	gly	contained	1023:1031	arg1	The extracted low-methoxyl pectin AND fucose	The extracted low-methoxyl pectin			fucose	Fterm		pectin			The extracted low-methoxyl pectin (DE = 33.65%) with high lightness contained considerable amounts of uronic acids and neutral monosaccharides (glucose, fucose, arabinose, galactose, rhamnose, and mannose).
31320048	4	4	gly	contained	1023:1031	arg1	The extracted low-methoxyl pectin AND rhamnose	The extracted low-methoxyl pectin			rhamnose	Fterm		pectin			The extracted low-methoxyl pectin (DE = 33.65%) with high lightness contained considerable amounts of uronic acids and neutral monosaccharides (glucose, fucose, arabinose, galactose, rhamnose, and mannose).
31200599	3	93	part_of	ECM	427:429	arg1	human pancreatic ECM composition	ECM		human pancreatic ECM composition		OGER	Site	ECM	Q13201	position	In this work, we characterized human pancreatic ECM composition before and after decellularization using isobaric dimethylated leucine (DiLeu) labeling for relative quantification of ECM proteins.
30528253	2	34	part_of	β-cyclodextrin-	344:358	arg1	β-cyclodextrin- multiwalled carbon nano-tube composite	cyclodextrin		β-cyclodextrin- multiwalled carbon nano-tube composite		Fterm	Site	cyclodextrin		composite	In this work, β-cyclodextrin- multiwalled carbon nano-tube composite was produced from the reaction of oxidized carbon nano-tube with cyclodextrin in the presence of the hydrazine hydrate, and subsequently attaching this composite to the iron oxide nano-particles.
31760000	7	55	gly	used	1279:1282	arg2	this composite			this composite						composite	The results indicate that this composite can be used as a potential adsorbent for treatment of water containing harmful substances.
31581071	3	73	gly	glycoprotein	487:498	arg1	glycan	glycoprotein			glycan	Fterm		glycoprotein			Epitope and glycan are two structure features of a glycoprotein.
31796784	0	29	part_of	Medium	24:29	arg1	Medium Composition	Medium		Medium Composition		OGER	Site	Medium		position	Modeling and Optimizing Medium Composition for Shoot Regeneration of Chrysanthemum via Radial Basis Function-Non-dominated Sorting Genetic Algorithm-II (RBF-NSGAII).
30528253	0	22	part_of	β-cyclodextrin-carbon	118:138	arg1	magnetic β-cyclodextrin-carbon nano-tube composite	cyclodextrin		magnetic β-cyclodextrin-carbon nano-tube composite		Fterm	Site	cyclodextrin		composite	Micro-solid phase extraction of some polycyclic aromatic hydrocarbons from environmental water samples using magnetic β-cyclodextrin-carbon nano-tube composite as a sorbent.
31826502	3	19	part_of	ATP/CS	526:531	arg1	attapulgite/chitosan (ATP/CS) composite	ATP		attapulgite/chitosan (ATP/CS) composite		OGER	Site	ATP		composite	Here, we describe a design of magnetic purifier, which has biomass-based structure by blending attapulgite/chitosan (ATP/CS) composite with bacterial cellulose nanofibrils (BCNs).
31279100	5	13	gly	used	575:578	arg2	Three compositions			Three compositions						positions	Three compositions of 3D porous CA scaffolds (2, 4, and 6 wt%) were used to investigate the effect of scaffold stiffness on PCa cell response with PC-3, C4-2B, and 22Rv1 cell lines.
28862732	12	25	part_of	n-HA/SAL/CS	1588:1598	arg1	the n-HA/SAL/CS composite	n-HA/SAL/CS		the n-HA/SAL/CS composite		PUBTATOR	Site	n-HA/SAL/CS	1431	composite	CONCLUSIONS Compressive strength of n-HA/SAL/CS can satisfy the needs of cancellous bone, and in vitro bioactivity and cytotoxicity tests results indicated that the n-HA/SAL/CS composite could act as an optimal bone repair material.
29909035	10	28	part_of	BC-DHP	1400:1405	arg1	BC-DHP composite	BC-DHP		BC-DHP composite		OGER	Site	BC-DHP	Q14117	composite	All obtained results confirmed BC-DHP composite as a promising hydrogel for wounds healing.
34123048	2	1	gly	sialylated	313:322	arg1	sialylated glycans				sialylated glycans						Precise determination of sialylated glycans, particularly their linkage isomers that can trigger distinct biological events and are indicative of different cancer types, remains a challenge, due to their complicated composition and limited structural differences.
31355147	3	55	gly	glycoproteins	579:591	arg1	lectin-mediated affinity capture glycoproteins	lectin-mediated affinity capture glycoproteins				Fterm		glycoproteins			Subsequently, lectin-mediated affinity capture glycoproteins, and MALDI-TOF/TOF-MS were employed to further acquire precise structural information of the altered glycans.
29865036	8	54	gly	fucosylated	1352:1362	arg1	fucosylated N-linked glycans				fucosylated N-linked glycans						The proportion of fucosylated N-linked glycans was decreased in GC (41.66%) compared with AG (43.63%) and HV (52.57%), as well as the fucosylated O-linked glycans was apparently decreased in GC (19.58%) compared with AG (25.43%) and HV (55.54%).
29865036	8	102	gly	fucosylated	1468:1478	arg1	the fucosylated O-linked glycans				the fucosylated O-linked glycans						The proportion of fucosylated N-linked glycans was decreased in GC (41.66%) compared with AG (43.63%) and HV (52.57%), as well as the fucosylated O-linked glycans was apparently decreased in GC (19.58%) compared with AG (25.43%) and HV (55.54%).
31581071	1	43	gly	glycoproteins	244:256	arg1	glycoproteins	glycoproteins				Fterm		glycoproteins			Sensitive and specific detection methods are critical to the detection of glycoproteins.
30339525	6	33	part_of	MWCNTs/SiO2/β-CD	1115:1130	arg1	the prepared MWCNTs/SiO2/β-CD composites	-CD		the prepared MWCNTs/SiO2/β-CD composites		PUBTATOR	Site	-CD	65057	composites	Furthermore, the stability and reusability studies demonstrated that the prepared MWCNTs/SiO2/β-CD composites are cost-effective adsorbents for the removal of parabens from water with high regeneration efficiency.
31117955	9	49	gly	composition	1425:1435	arg1	composition 2 Hex 1			position 2	composition 2 Hex 1					position 2	In Danish Jersey, a very strong QTL was detected for the OS with composition 2 Hex 1 HexNAc (isomer 1) on BTA11.
30444534	8	25	gly	used	1312:1315	arg2	synbiotic compositions			synbiotic compositions						positions	These extracts could be used as prebiotic, synbiotic compositions or novel food prototypes to treat dysbiosis associated with many diseases.
29449596	0	62	part_of	elastin-like	85:96	arg1	elastin-like peptides	elastin		elastin-like peptides		PUBTATOR	Site	elastin	2006	peptides	Heparan sulfates facilitate harmless amyloidogenic fibril formation interacting with elastin-like peptides.
30708003	2	12	gly	utilized	411:418	arg2	The resulting composite			The resulting composite						composite	The resulting composite, was utilized as an efficient heterogeneous catalyst for promoting Sonogashira and Heck reactions in the absence of any ligand and co-catalyst under mild reaction condition.
31422531	12	23	part_of	Chitosan/ZnO	1982:1993	arg1	Chitosan/ZnO NPs composite	Chitosan/ZnO NPs		Chitosan/ZnO NPs composite		OGER	Site	Chitosan/ZnO NPs	P0C0P6	composite	Chitosan/ZnO NPs composite can be used in any biosecurity program of poultry farms as an alternative to ineffective antimicrobial agents.
31422531	12	60	part_of	NPs	1995:1997	arg1	Chitosan/ZnO NPs composite	Chitosan/ZnO NPs		Chitosan/ZnO NPs composite		OGER	Site	Chitosan/ZnO NPs	P0C0P6	composite	Chitosan/ZnO NPs composite can be used in any biosecurity program of poultry farms as an alternative to ineffective antimicrobial agents.
30258536	4	23	gly	domain	906:911	arg1	rare N-glycans			domain	rare N-glycans					domain	We describe a novel synthetic approach to the human IgG1 Fc peptide having a bisected decasaccharide and its nonbisected counterpart compound, the signatures of antibodies involving Fc domain with rare N-glycans expected to show much higher ADCC/CDC than abundant IgG N-glycans, and their application to the SRM-based quantitative glycoproteomics.
30258536	4	64	gly	having	789:794	arg1	the human IgG1 Fc peptide AND a bisected decasaccharide and its nonbisected counterpart compound			the human IgG1 Fc peptide	a bisected decasaccharide and its nonbisected counterpart compound					peptide	We describe a novel synthetic approach to the human IgG1 Fc peptide having a bisected decasaccharide and its nonbisected counterpart compound, the signatures of antibodies involving Fc domain with rare N-glycans expected to show much higher ADCC/CDC than abundant IgG N-glycans, and their application to the SRM-based quantitative glycoproteomics.
29432186	8	18	gly	N-glycosylation	1014:1028	arg2	N-glycosylation sites			N-glycosylation sites						sites	By analyzing B-cell repertoires by next-generation sequencing, we demonstrate that N-glycosylation sites are introduced at positions in which glycans can affect antigen binding as a result of a specific clustering of progenitor glycosylation sites in the germline sequences of variable domain genes.
29432186	8	44	gly	glycosylation	1159:1171	arg2	progenitor glycosylation sites			progenitor glycosylation sites						sites	By analyzing B-cell repertoires by next-generation sequencing, we demonstrate that N-glycosylation sites are introduced at positions in which glycans can affect antigen binding as a result of a specific clustering of progenitor glycosylation sites in the germline sequences of variable domain genes.
31441702	0	13	part_of	Pen	42:44	arg1	Composition	Pen		Composition		OGER	Site	Pen	Q86UF1	position	Construction and Composition of the Squid Pen from Doryteuthis pealeii.
30385333	4	8	part_of	CAB	623:625	arg1	the CAB composite	CAB		the CAB composite		PUBTATOR	Site	CAB	56654	composite	Adsorption isotherms are in good agreement with the Freundlich model, yielding a high adsorption capacity for the CAB composite.
31687435	0	22	gly	glycoproteins	69:81	arg1	hepatic glycoproteins	hepatic glycoproteins				Fterm		glycoproteins			Data set for characterization of the glycosylation status of hepatic glycoproteins in mice fed a low-carbohydrate ketogenic diet.
31687435	0	74	gly	glycosylation	37:49	arg1	hepatic glycoproteins	hepatic glycoproteins				Fterm		glycoproteins			Data set for characterization of the glycosylation status of hepatic glycoproteins in mice fed a low-carbohydrate ketogenic diet.
30258536	0	85	gly	Nonfucosylated	61:74	arg1	Scarce Nonfucosylated IgG Fc N-Glycans				Scarce Nonfucosylated IgG Fc N-Glycans						Synthetic Glycopeptides Allow for the Quantitation of Scarce Nonfucosylated IgG Fc N-Glycans of Therapeutic Antibody.
31169501	6	12	part_of	GO/CNC	1647:1652	arg1	the hydrophilic and antibacterial GO/CNC nanocomposite	CNC		the hydrophilic and antibacterial GO/CNC nanocomposite		OGER	Site	CNC	P32418	nanocomposite	A lower biofouling level after three weeks' filtration of the actual micro-polluted source water further demonstrated that embedding the hydrophilic and antibacterial GO/CNC nanocomposite into the polymer matrix is an effective strategy to improve membrane anti-biofouling ability.
31636638	2	106	gly	glycoproteins	351:363	arg1	membrane-bound glycoproteins	membrane-bound glycoproteins				Fterm		glycoproteins			Composed of membrane-bound glycoproteins, sulfated proteoglycans and glycosaminoglycan side-chains, this structure is particularly essential for blood vascular barrier functions and leukocyte diapedesis.
29351237	4	3	gly	O-glycosylated	609:622	arg1	Ser52			Ser52 and Ser60						Ser52 and Ser60	The first ten glutamic acids of the N-terminal moiety are γ-carboxylated, Asn145 and Asn322 are N-glycosylated, and Ser52 and Ser60 are O-glycosylated.
29351237	4	21	gly	N-glycosylated	569:582	arg1	Asn322			Asn145 and Asn322						Asn145 and Asn322	The first ten glutamic acids of the N-terminal moiety are γ-carboxylated, Asn145 and Asn322 are N-glycosylated, and Ser52 and Ser60 are O-glycosylated.
30261640	5	6	part_of	PAni/MCC/CTAB	987:999	arg1	PAni/MCC/CTAB nanocomposite	MCC		PAni/MCC/CTAB nanocomposite		PUBTATOR	Site	MCC	4163	nanocomposite	The overlapping characteristic peaks of pure PAni and MCC caused peak broadening at 3263 cm-1 in the IR spectra of PAni/MCC/CTAB nanocomposite that revealed the interaction between NH of PAni and OH group of MCC via electrostatic interactions.
30968513	5	27	part_of	PVA-CNC	823:829	arg1	the PVA-CNC nanocomposite	PVA		the PVA-CNC nanocomposite		OGER	Site	PVA	P32926	nanocomposite	On the one hand, water-soluble poly(vinyl alcohol) (PVA) can be mixed with dispersed CNC upon CO2 bubbling for making the PVA-CNC nanocomposite.
31687435	2	2	gly	glycoproteins	443:455	arg1	hepatic glycoproteins	hepatic glycoproteins				Fterm		glycoproteins			The present article provides additional structural analysis data for the characterization of hepatic glycoproteins in mice fed a low-carbohydrate ketogenic diet (LCKD).
30776442	11	41	gly	used	1400:1403	arg2	the as-prepared CNF/AgNP composite			the as-prepared CNF/AgNP composite						composite	These results suggest that the as-prepared CNF/AgNP composite could potentially be used as an antimicrobial material in active food packaging systems.
29363966	0	48	part_of	Impact	40:45	arg1	Composition	Inulin Impact		Composition		OGER	Site	Inulin Impact	Q9P2X3	position,	Arabinoxylo-Oligosaccharides and Inulin Impact Inter-Individual Variation on Microbial Metabolism and Composition, Which Immunomodulates Human Cells.
31181275	7	55	gly	pectin	1341:1346	arg1	monosaccharide composition	pectin			monosaccharide composition	Fterm		pectin			FTIR spectroscopy and HPLC photodiode array detector revealed that conventional and novel extraction technologies do not change the chemical structure and monosaccharide composition of pectin significantly.
35518704	0	40	gly	O-glycosylation	12:26	arg1	modified N-linked oligosaccharide (Man12GlcNAc2∼Man16GlcNAc2) Pichia pastoris				modified N-linked oligosaccharide (Man12GlcNAc2∼Man16GlcNAc2) Pichia pastoris						Engineering O-glycosylation in modified N-linked oligosaccharide (Man12GlcNAc2∼Man16GlcNAc2) Pichia pastoris strains.
30258536	6	30	gly	glycopeptides	1605:1617	arg2	the synthetic Fc glycopeptides			the synthetic Fc glycopeptides						glycopeptides	Strikingly, SRM assay using the synthetic Fc glycopeptides as calibration standards uncovered the occurrence of the targeted IgG1 Fc fragment carrying a nonfucosylated and bisected (315 fmol, 0.20%) and its nonbisected counterpart (1154 fmol, 0.73%) in the tryptic digests from 158 pmol of anticancer antibody Herceptin (trastuzumab).
31422531	12	4	gly	used	2016:2019	arg2	Chitosan/ZnO NPs composite			Chitosan/ZnO NPs composite						composite	Chitosan/ZnO NPs composite can be used in any biosecurity program of poultry farms as an alternative to ineffective antimicrobial agents.
31730961	1	20	part_of	MOF	139:141	arg1	a novel MOF(Fe)@NaAlg aerogels composite	MOF		a novel MOF(Fe)@NaAlg aerogels composite		OGER	Site	MOF	Q9H7Z6	composite	In this work, a novel MOF(Fe)@NaAlg aerogels composite were fabricated by a facile method of ion cross-linking, and characterized via Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), scanning electron microscopy (SEM), thermogravimetric analysis (TG), X-ray photoelectron spectroscopy (XPS) and BET surface area analysis.
31730961	1	26	part_of	Fe	143:144	arg1	a novel MOF(Fe)@NaAlg aerogels composite	Fe		a novel MOF(Fe)@NaAlg aerogels composite		PUBTATOR	Site	Fe	2960	composite	In this work, a novel MOF(Fe)@NaAlg aerogels composite were fabricated by a facile method of ion cross-linking, and characterized via Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), scanning electron microscopy (SEM), thermogravimetric analysis (TG), X-ray photoelectron spectroscopy (XPS) and BET surface area analysis.
30826401	5	10	part_of	CNC	936:938	arg1	CNC hard domains	CNC		CNC hard domains		OGER	Site	CNC	P32418	domains	In addition, a micro-phase separated morphology (PBA soft domains, and PMMA and CNC hard domains) of MCNCs/PBA-co-PMMA nanocomposites was observed.
31725254	9	43	part_of	[CEL+EIS	1856:1863	arg1	The [CEL+EIS@SEC] composites	CEL		The [CEL+EIS@SEC] composites		OGER	Site	CEL	P19835	composites	The [CEL+EIS@SEC] composites are superior to any other available materials based on encapsulated PCM because they are not only robust, reliable, and stable and have strong mechanical properties.
30359004	3	12	part_of	chitin	685:690	arg1	the chemical composition	chitin		the chemical composition		Fterm	Site	chitin		position	Fourier transform infrared (FT-IR) spectroscopy, thermogravimetric analysis (TGA), X-ray diffraction (XRD), and scanning electron microscopy (SEM) were used to investigate changes in the chemical composition of extracted chitin.
31295525	9	28	part_of	CMCNF-CIP-MMT	1303:1315	arg1	the 3 wt% CMCNF-CIP-MMT composite	CMCNF-CIP		the 3 wt% CMCNF-CIP-MMT composite		OGER	Site	CMCNF-CIP	Q5VWP3	composite	An anti-bacterial test revealed that the 3 wt% CMCNF-CIP-MMT composite displayed the most constant antibacterial activity over 12 days.
31725254	4	104	part_of	[CEL+EIS	1003:1010	arg1	[CEL+EIS@SEC] composites	CEL		[CEL+EIS@SEC] composites		OGER	Site	CEL	P19835	composites	[EIS@SEC] can, therefore, be incorporated into cellulose (CEL) composites with a synthetic process that uses the simple ionic liquid butylmethylimmidazolium chloride to produce [CEL+EIS@SEC] composites.
30199712	3	44	gly	utilized	412:419	arg2	This composite			This composite						composite	This composite was utilized for enhancement of the conductivity of the immunosensor.
30258536	3	31	gly	glycopeptides	529:541	arg2	tryptic IgG Fc glycopeptides			tryptic IgG Fc glycopeptides						glycopeptides	The present study communicates that selected reaction monitoring (SRM)-based assay of tryptic IgG Fc glycopeptides is a promising approach for the characterization of antibodies when combined with structure-defined synthetic Fc peptides having a focused N-glycoform as a calibration standard.
31295525	7	5	part_of	CIP-MMT	1010:1016	arg1	the CIP-MMT composite	CIP		the CIP-MMT composite		OGER	Site	CIP	Q5VWP3	composite	Increasing the CMCNF content delayed the erosion of the CMCNF matrix and prevented rapid dissolution of the CIP-MMT composite.
29773400	3	26	part_of	Ag	731:732	arg1	novel Ag NPs@ HKUST-1@ CFs composites	Ag NPs		novel Ag NPs@ HKUST-1@ CFs composites		OGER	Site	Ag NPs	P0C0P6	composites	The silver nanoparticles (Ag NPs) were immobilized and well-dispersed into the pores and/or onto the surfaces of HKUST-1 via in situ microwave reduction, resulting in the formation of novel Ag NPs@ HKUST-1@ CFs composites.
29773400	3	42	part_of	NPs	734:736	arg1	novel Ag NPs@ HKUST-1@ CFs composites	Ag NPs		novel Ag NPs@ HKUST-1@ CFs composites		OGER	Site	Ag NPs	P0C0P6	composites	The silver nanoparticles (Ag NPs) were immobilized and well-dispersed into the pores and/or onto the surfaces of HKUST-1 via in situ microwave reduction, resulting in the formation of novel Ag NPs@ HKUST-1@ CFs composites.
30328055	0	15	part_of	milk	121:124	arg1	milk composition	milk		milk composition		PUBTATOR	Site	milk	100532204	position	5'-flanking variants of equine casein genes (CSN1S1, CSN1S2, CSN2, CSN3) and their relationship with gene expression and milk composition.
30328055	0	79	part_of	variants	12:19	arg1	milk composition	variants		milk composition		Fterm	Site	variants		position	5'-flanking variants of equine casein genes (CSN1S1, CSN1S2, CSN2, CSN3) and their relationship with gene expression and milk composition.
30910957	3	37	part_of	mucin	551:555	arg1	mucin domains	mucin		mucin domains		PUBTATOR	Site	mucin	100508689	domains	Mucin biology has been difficult to study at the molecular level, in part, because methods to manipulate and structurally characterize mucin domains are lacking.
30910957	2	35	gly	glycoproteins	261:273	arg1	Mucin-domain glycoproteins	Mucin-domain glycoproteins				Fterm		glycoproteins			Mucin-domain glycoproteins are known to be key players in a host of human diseases, especially cancer, wherein mucin expression and glycosylation patterns are altered.
31307013	3	10	gly	glycopeptide	647:658	arg2	glycopeptide			glycopeptide						glycopeptide	METHODS AND SUBJECTS Molecular biological, biochemical and glycopeptide analyses were used to examine how N-glycosylation at specific sites, including at N347 within the RCL, affect CBG ELISA or steroid-binding capacity assay (BCA) measurements.
31307013	3	58	gly	N-glycosylation	694:708	arg1	at N347			N347						N347	METHODS AND SUBJECTS Molecular biological, biochemical and glycopeptide analyses were used to examine how N-glycosylation at specific sites, including at N347 within the RCL, affect CBG ELISA or steroid-binding capacity assay (BCA) measurements.
31307013	3	58	gly	N-glycosylation	694:708	arg1	specific sites			sites						sites	METHODS AND SUBJECTS Molecular biological, biochemical and glycopeptide analyses were used to examine how N-glycosylation at specific sites, including at N347 within the RCL, affect CBG ELISA or steroid-binding capacity assay (BCA) measurements.
29464911	4	9	part_of	glucagon-like	864:876	arg1	serum glucagon-like peptide 1	glucagon-l		serum glucagon-like peptide 1		PUBTATOR	Site	glucagon-l	24952	peptide	RESULTS In OP rats, RS elicited robust fermentation (increased cecal contents, short-chain fatty acids, and serum glucagon-like peptide 1).
31040323	1	55	part_of	Host	131:134	arg1	Cationic Host Defense Peptides	Host		Cationic Host Defense Peptides		OGER		Host			Cationic Host Defense Peptides (HDPs) are endowed with a broad variety of activities, including direct antimicrobial properties and modulatory roles in the innate immune response.
31554133	5	13	part_of	FA-β-CD	954:960	arg1	a novel and potential functional composition	-CD		a novel and potential functional composition		PUBTATOR	Site	-CD	65057	position	Taken together, the present study indicates that the FA-β-CD conjugate might be a novel and potential functional composition for application in food and medicine.
31770560	7	8	gly	used	1167:1170	arg2	these composites			these composites						composites	The good mechanical properties, water resistance and antimicrobial activity against pathogens recommend these composites to be used in the manufacture of packaging materials.
30997002	5	7	gly	deglycosylated	905:918	arg1	the fully deglycosylated protein	the fully deglycosylated protein				Fterm		protein			Hydrogen/deuterium exchange mass spectrometry (HDX-MS) data support this, with lower global deuterium uptake in solution when comparing intact to the fully deglycosylated protein.
31016304	10	64	gly	enoxaparin	1577:1586	arg1	The disaccharide composition	enoxaparin			The disaccharide composition	Fterm		enoxaparin			The disaccharide composition, sequence and the variety of glycans of an enoxaparin are more related to its AT binding-based anticoagulant activity.
31016304	10	64	gly	enoxaparin	1577:1586	arg1	glycans	enoxaparin			glycans	Fterm		enoxaparin			The disaccharide composition, sequence and the variety of glycans of an enoxaparin are more related to its AT binding-based anticoagulant activity.
30258536	6	78	part_of	IgG1	1685:1688	arg1	the targeted IgG1 Fc fragment	IgG1		the targeted IgG1 Fc fragment		OGER	Site	IgG1	P01857	fragment	Strikingly, SRM assay using the synthetic Fc glycopeptides as calibration standards uncovered the occurrence of the targeted IgG1 Fc fragment carrying a nonfucosylated and bisected (315 fmol, 0.20%) and its nonbisected counterpart (1154 fmol, 0.73%) in the tryptic digests from 158 pmol of anticancer antibody Herceptin (trastuzumab).
31739031	4	22	gly	galactose	528:536	arg1	The SLP pectin	pectin			galactose	Fterm		pectin			The SLP pectin was rich in galacturonic acid and galactose (87.2 mol%), high in molecular weight (615.836 kDa) and low in degree of esterification (1.2-35.1%).
31739031	4	30	gly	acid	519:522	arg1	The SLP pectin	pectin			acid	Fterm		pectin			The SLP pectin was rich in galacturonic acid and galactose (87.2 mol%), high in molecular weight (615.836 kDa) and low in degree of esterification (1.2-35.1%).
31189652	9	65	part_of	O-antigen	1271:1279	arg1	O-antigen composition	O-antigen		O-antigen composition		Cterm	Site	O-antigen		position	DNA ejection triggered by LPS from either host showed similar velocities, so particle opening is thus a process independent of O-antigen composition and the recognizing TSP.
29865036	7	8	gly	fucosylated	1246:1256	arg1	ten fucosylated O-linked glycans				ten fucosylated O-linked glycans						Among these, six fucosylated N-linked glycansand four O-linked glycans exhibited significantly increased expression levels in GC, while five fucosylated N-linked glycans and ten fucosylated O-linked glycans exhibited significantly decreased expression levels in GC.
29865036	7	34	gly	fucosylated	1209:1219	arg1	five fucosylated N-linked glycans				five fucosylated N-linked glycans						Among these, six fucosylated N-linked glycansand four O-linked glycans exhibited significantly increased expression levels in GC, while five fucosylated N-linked glycans and ten fucosylated O-linked glycans exhibited significantly decreased expression levels in GC.
29865036	7	92	gly	fucosylated	1085:1095	arg1	six fucosylated N-linked glycansand four O-linked glycans				six fucosylated N-linked glycansand four O-linked glycans						Among these, six fucosylated N-linked glycansand four O-linked glycans exhibited significantly increased expression levels in GC, while five fucosylated N-linked glycans and ten fucosylated O-linked glycans exhibited significantly decreased expression levels in GC.
31256371	7	26	gly	glycoproteins	1249:1261	arg1	glycoproteins	glycoproteins				Fterm		glycoproteins			Such simple hydrazinolysis protocols should benefit not only the biotechnology industry but also academic laboratories for characterization of glycoproteins.
31152956	3	47	part_of	DES	452:454	arg1	DES composition	DES		DES composition		OGER	Site	DES	P17661	position,	Effect of DES composition, DES-buffer ratio, temperature, pH, substrate ratio and substrate concentration was systematically investigated.
30439664	5	36	part_of	calpain	1088:1094	arg1	the active site	calpain		the active site		OGER	Site	calpain		site	Among the most abundant compounds detected in the various phases, the polyphenol quercetin exhibited the best affinity and free binding energy towards the active site of the calcium-dependent protease calpain.
30755666	3	14	part_of	proteins	532:539	arg1	the amino-acid sequences	proteins		the amino-acid sequences		Fterm	Site	proteins		sequences	Here, we compared the amino-acid sequences of 16 proteins present in the corneal stromal matrix of 14 different animal species using Basic Local Alignment Search Tool, and calculated a similarity score compared to the respective human sequence.
35518704	2	9	gly	O-mannosylated	343:356	arg1	yeast-specific O-mannosylated proteins	yeast-specific O-mannosylated proteins				Fterm		proteins			Both N- and O-linked oligosaccharides engineered yeast have been attractive prospects, since yeast-specific O-mannosylated proteins were reported to induce an aberrant immune response and alter pharmacokinetics in vivo.
29885215	2	1	gly	utilized	309:316	arg2	depsipeptides			depsipeptides						depsipeptides	Previous studies on depsipeptides utilized electrospray ionization ion mobility quadrupole time-of-flight (ESI-IM-QTOF) tandem mass spectrometry; such analysis was thorough yet time-consuming.
30138539	2	22	gly	proteins	353:360	arg1	important determinants	proteins			important determinants	Fterm		proteins			Irrespective of the dialysis modality, hemodialysis (HD) or peritoneal dialysis (PD), the amount and composition of proteins that are removed are important determinants of the biocompatibility of the therapy.
32228991	6	39	part_of	acid/α-cyclodextrin	1469:1487	arg1	citric acid/α-cyclodextrin composite	α-cyclodextrin		citric acid/α-cyclodextrin composite		Fterm	Site	α-cyclodextrin		composite	The calculated energies are as follow: 1) quercetin and citric acid: ΔEb = -16.58 kcal/mol, 2) quercetin and α-cyclodextrin: ΔEb = -46.98 kcal/mol, and 3) quercetin and citric acid/α-cyclodextrin composite: ΔEb = -40.15 kcal/mol.
29791242	1	68	part_of	insulin	137:143	arg1	the primary acting site	insulin		the primary acting site		PUBTATOR	Site	insulin	3630	site	Liver is the primary acting site of insulin.
34123048	0	91	gly	sialylated	50:59	arg1	sialylated glycans				sialylated glycans						Biomimetic nanochannels for the discrimination of sialylated glycans via a tug-of-war between glycan binding and polymer shrinkage.
30711739	6	61	part_of	MMT/CMC1:1	1313:1322	arg1	the MMT/CMC1:1(600) composite	MMT/CMC1		the MMT/CMC1:1(600) composite		PUBTATOR	Site	MMT/CMC1	152100	composite	The experimental results also showed that the adsorption of βE2 on the MMT/CMC1:1(600) composite could contribute to hydrophobic partitioning, π-π staking interaction, H-bond interaction, pore-filling effect and simple van der Waals interaction.
29449596	4	18	part_of	elastin-like	756:767	arg1	synthetic amyloidogenic elastin-like peptides	elastin		synthetic amyloidogenic elastin-like peptides		PUBTATOR	Site	elastin	2006	peptides	Therefore, we investigated the interactions of HSs, obtained from different sources and exhibiting various degree of sulfation, with synthetic amyloidogenic elastin-like peptides (ELPs), also looking at the effects of these interactions on cell viability and cell behavior using in vitro cultured fibroblasts, as a prototype of mesenchymal cells known to modulate the soft connective tissue environment.
33463193	3	21	gly	used	422:425	arg2	a new chitosan/zinc oxide nanoparticle (CZNC) composite			a new chitosan/zinc oxide nanoparticle (CZNC) composite						composite	Recently, a new chitosan/zinc oxide nanoparticle (CZNC) composite has been used as a promising "green" biocide.
30426864	3	13	part_of	calcitonin	389:398	arg1	calcitonin gene-related peptide	calcitonin		calcitonin gene-related peptide		OGER	Site	calcitonin	P01258	peptide	Naringin and calcitonin gene-related peptide were used as drugs to prepare drug-loaded scaffolds by direct printing or surface absorption.
31905655	3	37	part_of	CuFe2O4/CNC	456:466	arg1	the CuFe2O4/CNC composites	CuFe2O4/CNC		the CuFe2O4/CNC composites		OGER	Site	CuFe2O4/CNC	P32418	composites	Ag NPs were then deposited on the CuFe2O4/CNC composites via an in situ reduction directed by dopamine polymerization (PDA).
30910957	1	45	gly	O-glycosylated	137:150	arg1	Mucin domains			domains						domains	Mucin domains are densely O-glycosylated modular protein domains that are found in a wide variety of cell surface and secreted proteins.
31256371	1	1	gly	glycoproteins	178:190	arg1	whole glycoproteins	whole glycoproteins				Fterm		glycoproteins			Analysis of carbohydrate structures is an integral part of understanding the structure-function relationship of glycans as well as whole glycoproteins.
31650194	8	5	part_of	BNC-based	1265:1273	arg1	BNC-based composites	BNC		BNC-based composites		OGER	Site	BNC	Q01954	composites	This strategy represents a simple approach towards the production of BNC and BNC-based composites.
29664208	5	12	part_of	precursor	854:862	arg1	the thermal decomposition	precursor		the thermal decomposition		Fterm	Site	precursor		position	Monodisperse USPIO cores, with precisely controlled core diameter (dC ) were synthesized via the thermal decomposition of iron(III)-oleate precursor.
29501817	11	62	part_of	receptor	2040:2047	arg1	the receptor binding domain	receptor		the receptor binding domain		Fterm	Site	receptor		domain	We further confirmed that 26SCS was spatially combined with VEGF in a "lying manner", and this spatial arrangement was more conducive to exposure of the receptor binding domain of VEGF.
29501817	11	65	part_of	VEGF	2067:2070	arg1	the receptor binding domain	VEGF		the receptor binding domain		PUBTATOR	Site	VEGF	P15692	domain	We further confirmed that 26SCS was spatially combined with VEGF in a "lying manner", and this spatial arrangement was more conducive to exposure of the receptor binding domain of VEGF.
30258536	4	89	part_of	IgG1	773:776	arg1	the human IgG1 Fc peptide	IgG1		the human IgG1 Fc peptide		OGER	Site	IgG1	P01857	peptide	We describe a novel synthetic approach to the human IgG1 Fc peptide having a bisected decasaccharide and its nonbisected counterpart compound, the signatures of antibodies involving Fc domain with rare N-glycans expected to show much higher ADCC/CDC than abundant IgG N-glycans, and their application to the SRM-based quantitative glycoproteomics.
30755666	2	11	part_of	proteins	354:361	arg1	composition	proteins		composition		Fterm	Site	proteins		position	The selection of an appropriate animal model must take into consideration the differences in the composition and structure of corneal proteins between humans and other animal species in order to minimize immune response and improve outcome of the xenotransplant.
31183754	2	13	part_of	chitosan/rarasaponin/bentonite	233:262	arg1	The produced chitosan/rarasaponin/bentonite (CRB) composite	rarasaponin		The produced chitosan/rarasaponin/bentonite (CRB) composite		Fterm	Site	rarasaponin		composite	The produced chitosan/rarasaponin/bentonite (CRB) composite exhibits outstanding adsorption capability toward copper metal ions (Cu(II)).
30507075	12	71	part_of	ECM	1680:1682	arg1	the biochemical composition	ECM		the biochemical composition		OGER	Site	ECM	Q13201	position	Compared with the control groups, the NMP group significantly promoted the expression of chondrocyte ECM in vivo (P<0.05), as shown by analysis of the biochemical composition of chondrocyte ECM.
29432186	4	30	gly	domain	517:522	arg1	variable domain glycans				variable domain glycans						High levels of variable domain glycans have been associated with autoantibodies in rheumatoid arthritis, as well as certain follicular lymphomas.
31253333	0	46	part_of	mannoproteins	76:88	arg1	composition	mannoproteins		composition		Fterm	Site	mannoproteins		position	Characterization of the composition and the techno-functional properties of mannoproteins from Saccharomyces cerevisiae yeast cell walls.
31252111	2	45	part_of	β-cyclodextrin	389:402	arg1	a nanocomposite	β-cyclodextrin		a nanocomposite		Fterm	Site	β-cyclodextrin		nanocomposite	In this work, we reported a nanocomposite of β-cyclodextrin and three-dimensional graphene (3D CD@RGO) to enhance the adsorption affinity and capacity for mercury with low concentrations.
31028613	15	20	gly	fucosylated	2038:2048	arg1	fucosylated oligosaccharides				fucosylated oligosaccharides						These results could be explained if cytosolic xyloglucan α-fucosidases are the ancestral state in angiosperms, with fucosylated oligosaccharides transported across the plasma membrane.
31581071	6	1	gly	epitope	968:974	arg1	the peptide epitope and glycans-imprinted Raman-active silver nanoparticles				the peptide epitope and glycans-imprinted Raman-active silver nanoparticles						It relies on double recognition towards a target glycoprotein by two different types of MIPs, using epitope-imprinted gold nanoparticles (AuNPs)-coated slide as capturing substrate to recognize the peptide epitope and glycans-imprinted Raman-active silver nanoparticles as labeling nanotags to recognize the glycans.
31581071	6	42	gly	peptide	960:966	arg1	the peptide epitope				the peptide epitope						It relies on double recognition towards a target glycoprotein by two different types of MIPs, using epitope-imprinted gold nanoparticles (AuNPs)-coated slide as capturing substrate to recognize the peptide epitope and glycans-imprinted Raman-active silver nanoparticles as labeling nanotags to recognize the glycans.
31581071	6	65	gly	glycoprotein	811:822	arg1	a target glycoprotein	a target glycoprotein				Fterm		glycoprotein			It relies on double recognition towards a target glycoprotein by two different types of MIPs, using epitope-imprinted gold nanoparticles (AuNPs)-coated slide as capturing substrate to recognize the peptide epitope and glycans-imprinted Raman-active silver nanoparticles as labeling nanotags to recognize the glycans.
35518704	1	55	gly	glycoproteins	179:191	arg1	therapeutic glycoproteins	glycoproteins			humanized N-linked oligosaccharides	Fterm		glycoproteins			Yeast have been engineered for the production of therapeutic glycoproteins with humanized N-linked oligosaccharides.
30258536	3	104	part_of	IgG	522:524	arg1	tryptic IgG Fc glycopeptides	IgG		tryptic IgG Fc glycopeptides		Cterm	Site	IgG		glycopeptides	The present study communicates that selected reaction monitoring (SRM)-based assay of tryptic IgG Fc glycopeptides is a promising approach for the characterization of antibodies when combined with structure-defined synthetic Fc peptides having a focused N-glycoform as a calibration standard.
31189652	3	58	part_of	multi-O-antigen-specific	507:530	arg1	a contractile tail	multi		a contractile tail		OGER	Site	multi		tail	For the first time, we show time-resolved DNA ejection from a bacteriophage with a contractile tail, the multi-O-antigen-specific Salmonella myovirus Det7.
31730966	2	10	part_of	magnetic-CS-PAA	363:377	arg1	a magnetic-CS-PAA (MCS-PAA) nanocomposite	magnetic-CS-PAA (MCS		a magnetic-CS-PAA (MCS-PAA) nanocomposite		OGER	Site	magnetic-CS-PAA (MCS	P49901	nanocomposite	In order to facilitate recovery, magnetic nanoparticles were incorporated in CS-PAA to obtain a magnetic-CS-PAA (MCS-PAA) nanocomposite.
31730966	2	22	part_of	MCS-PAA	380:386	arg1	a magnetic-CS-PAA (MCS-PAA) nanocomposite	magnetic-CS-PAA (MCS		a magnetic-CS-PAA (MCS-PAA) nanocomposite		OGER	Site	magnetic-CS-PAA (MCS	P49901	nanocomposite	In order to facilitate recovery, magnetic nanoparticles were incorporated in CS-PAA to obtain a magnetic-CS-PAA (MCS-PAA) nanocomposite.
31924053	3	33	part_of	SA-Ca2+-GO	378:387	arg1	The resultant SA-Ca2+-GO composites	SA-Ca2		The resultant SA-Ca2+-GO composites		OGER	Site	SA-Ca2	P00918	composites	The resultant SA-Ca2+-GO composites were freeze-dried to produce SA-Ca2+-GO hybrids, which were then examined by Fourier transform infrared (FT-IR) spectrometry, field emission scanning electron microscopy (FESEM) and atomic force microscopy (AFM).
31314132	1	25	part_of	enzymes	120:126	arg1	exquisite active sites	enzymes		exquisite active sites		Fterm	Site	enzymes		sites	Nature has evolved enzymes with exquisite active sites that catalyze biotransformations with high efficiency.
30026097	1	9	gly	used	147:150	arg2	ε-Poly-l-lysine			ε-Poly-l-lysine						lysine	ε-Poly-l-lysine (ε-PL) is widely used as an antibacterial agent because of its broad antimicrobial spectrum.
30339525	0	45	part_of	multi-walled	68:79	arg1	mesostructured silica coated multi-walled carbon nanotubes composites	multi		mesostructured silica coated multi-walled carbon nanotubes composites		OGER	Site	multi		composites	Fabrication of β-cyclodextrin modified mesostructured silica coated multi-walled carbon nanotubes composites and application for paraben removal.
30785441	6	16	part_of	PKP-NPs	834:840	arg1	phenolic composition	NPs		phenolic composition		OGER	Site	NPs	P0C0P6	position	Through establishment of a simulated gastrointestinal digestion model, the release behavior and phenolic composition of PKP-NPs were respectively investigated.
30910957	4	24	part_of	mucin	707:711	arg1	mucin domains	mucin		mucin domains		PUBTATOR	Site	mucin	100508689	domains	Here, we demonstrate that secreted protease of C1 esterase inhibitor (StcE), a bacterial protease from Escherichia coli, cleaves mucin domains by recognizing a discrete peptide- and glycan-based motif.
35518704	6	46	gly	glycoproteins	1261:1273	arg1	therapeutic glycoproteins	glycoproteins			engineered N-	Fterm		glycoproteins			Thus, by disrupting O-mannosyltransferase PMT1 in an N-glycosylation engineered Pichia pastoris strain, we generated an effective glycoengineered Pichia pastoris strain to effectively produce therapeutic glycoproteins with both engineered N- and O-linked oligosaccharides.
35518704	6	46	gly	glycoproteins	1261:1273	arg1	therapeutic glycoproteins	glycoproteins			O-linked oligosaccharides	Fterm		glycoproteins			Thus, by disrupting O-mannosyltransferase PMT1 in an N-glycosylation engineered Pichia pastoris strain, we generated an effective glycoengineered Pichia pastoris strain to effectively produce therapeutic glycoproteins with both engineered N- and O-linked oligosaccharides.
31129253	13	62	part_of	ECM	1722:1724	arg1	ECM compositions	ECM		ECM compositions		OGER	Site	ECM	Q13201	positions,	In conclusions, chitosan/PCL blends membrane provided a favorable environment for CECs in terms of ECM compositions, therefore enhancing the growth and differentiation.
30258536	1	76	part_of	IgG	142:144	arg1	the IgG Fc domain	IgG		the IgG Fc domain		Cterm	Site	IgG		domain	Glycans attached to the IgG Fc domain affect strongly biological activities such as antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC) of therapeutic antibodies.
31687435	3	36	gly	glycoproteins	531:543	arg1	hepatic glycoproteins	hepatic glycoproteins				Fterm		glycoproteins			Analysis of hepatic glycoproteins by enzyme-linked assay using the lectins UEA-I, ConA, LCA, and WGA showed that the LCKD decreased mature forms of complex-type glycans but increased immature forms of glycans on glycoproteins.
31687435	3	41	gly	glycoproteins	723:735	arg1	glycoproteins	glycoproteins				Fterm		glycoproteins			Analysis of hepatic glycoproteins by enzyme-linked assay using the lectins UEA-I, ConA, LCA, and WGA showed that the LCKD decreased mature forms of complex-type glycans but increased immature forms of glycans on glycoproteins.
31687435	3	65	gly	glycans	712:718	arg1	glycoproteins	glycoproteins			glycans	Fterm		glycoproteins			Analysis of hepatic glycoproteins by enzyme-linked assay using the lectins UEA-I, ConA, LCA, and WGA showed that the LCKD decreased mature forms of complex-type glycans but increased immature forms of glycans on glycoproteins.
31142049	1	1	part_of	gut	271:273	arg1	the gut microbiota composition	gut		the gut microbiota composition		PUBTATOR	Site	gut	110006	position,	Different gastrointestinal disorders, including inflammatory bowel diseases (IBD), have been linked to alterations of the gut microbiota composition, namely dysbiosis.
31047046	1	37	part_of	chitin	138:143	arg1	magnetic chitin composite	chitin		magnetic chitin composite		Fterm	Site	chitin		composite	A simple, convenient and inexpensive method for the preparation of magnetic chitin composite, in which magnetite particles are densely covered with the polysaccharide shell has been developed.
31820139	4	1	gly	used	528:531	arg2	A nanocomposite			A nanocomposite						nanocomposite	A nanocomposite consisting of graphene oxide and chitosan (GO-chit) was used to immobilize the aptamer via formation of an amide link.
30606518	3	10	part_of	QCS/CuS-NPs	506:516	arg1	The obtained QCS/CuS-NPs composites	NPs		The obtained QCS/CuS-NPs composites		OGER	Site	NPs	P0C0P6	composites	The obtained QCS/CuS-NPs composites (CuS@QCS-NPs) were spherical and stable with an average diameter of 5.6 nm, and showed strong NIR absorbance for photothermal conversion.
31196533	6	4	gly	utilized	911:918	arg2	the GC/MGO-SO3H composite			the GC/MGO-SO3H composite						composite	This study has demonstrated that the GC/MGO-SO3H composite could be utilized as an efficient and with high speed.
30729136	4	31	part_of	haemagglutinin	636:649	arg1	the hydrophilic haemagglutinin (HA) domain	haemagglutinin		the hydrophilic haemagglutinin (HA) domain		Fterm	Site	haemagglutinin		domain	In this study, we demonstrate that the recombinant H1 vaccine based on the hydrophilic haemagglutinin (HA) domain and produced in the yeast system elicited high titres of serum haemagglutination-inhibiting antibodies in mice.
31199651	6	72	part_of	SAPHEC	958:963	arg1	their chemically bonded function nanocomposites SI-PSRF/SAPWS and SI-PSRF/SAPHEC	HEC		their chemically bonded function nanocomposites SI-PSRF/SAPWS and SI-PSRF/SAPHEC		OGER	Site	HEC		nanocomposites	Due to the differences between activity and number of functional groups in WS and HEC, the water absorption properties and degradation performances of SAPWS and SAPHEC and their chemically bonded function nanocomposites SI-PSRF/SAPWS and SI-PSRF/SAPHEC are different.
31181275	4	61	gly	UMAE-pectin	698:708	arg1	the maximum galacturonic acid content	pectin			the maximum galacturonic acid content	Fterm		pectin			The UMAE-pectin with the maximum galacturonic acid content (76.85%) and molecular weight (6.91 × 103 kDa) presented the highest emulsifying activity (61.2-61.3%) and emulsion stability (94.3-95.2%) with a monomodal droplet size distribution at cold and ambient storage temperatures.
31725254	6	17	part_of	[CEL+EIS	1217:1224	arg1	the [CEL+EIS@SEC] composites	CEL		the [CEL+EIS@SEC] composites		OGER	Site	CEL	P19835	composites	The energies associated with the crystallization and melting processes enable the [CEL+EIS@SEC] composites to fully exhibit the properties expected of PCMs, i.e., heating the surroundings when they cool and absorbing energy from the surroundings when they warm.
29432186	7	45	gly	domain	872:877	arg1	variable domain glycans				variable domain glycans						Our aim was to elucidate the role of variable domain glycans during antigen-specific antibody responses.
31016304	10	64	part_of	enoxaparin	1577:1586	arg1	sequence	enoxaparin		sequence		Fterm	Site	enoxaparin		sequence	The disaccharide composition, sequence and the variety of glycans of an enoxaparin are more related to its AT binding-based anticoagulant activity.
