{"count":10,"next":null,"previous":null,"results":[{"gene_data":{"alias":["ZNF698","bA145L22","bA145L22.2"],"biotype":"protein_coding","hgnc_id":"HGNC:18791","gene_name":"ZFP57 zinc finger protein","omim_gene":["612192"],"alias_name":null,"gene_symbol":"ZFP57","hgnc_symbol":"ZFP57","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"6:29640169-29648887","ensembl_id":"ENSG00000204644"}},"GRch38":{"90":{"location":"6:29672392-29681110","ensembl_id":"ENSG00000204644"}}},"hgnc_date_symbol_changed":"2005-07-20"},"entity_type":"gene","entity_name":"ZFP57","confidence_level":"0","penetrance":"Complete","mode_of_pathogenicity":"","publications":[],"evidence":["Expert Review Removed","UKGTN","Illumina TruGenome Clinical Sequencing Services","Radboud University Medical Center, Nijmegen"],"phenotypes":["Diabetes mellitus, transient neonatal, 1, 601410","Transient Neonatal Diabetes, Recessive","Neonatal Diabetes"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":87,"hash_id":"55d1e3f522c1fc237fbd46e9","name":"Multi-organ autoimmune diabetes","disease_group":"Endocrine disorders","disease_sub_group":"Disorders of unusual phenotypes","status":"public","version":"1.7","version_created":"2017-11-05T02:37:20.000817Z","relevant_disorders":[],"stats":{"number_of_genes":42,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"}]}},{"gene_data":{"alias":["ZNF698","bA145L22","bA145L22.2"],"biotype":"protein_coding","hgnc_id":"HGNC:18791","gene_name":"ZFP57 zinc finger protein","omim_gene":["612192"],"alias_name":null,"gene_symbol":"ZFP57","hgnc_symbol":"ZFP57","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"6:29640169-29648887","ensembl_id":"ENSG00000204644"}},"GRch38":{"90":{"location":"6:29672392-29681110","ensembl_id":"ENSG00000204644"}}},"hgnc_date_symbol_changed":"2005-07-20"},"entity_type":"gene","entity_name":"ZFP57","confidence_level":"3","penetrance":"Complete","mode_of_pathogenicity":"","publications":["PMID: 18622393"],"evidence":["Expert Review Green","Literature"],"phenotypes":["Phenotypes consistent with hypomethylation at multiple imprinted loci"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":131,"hash_id":"553f9744bb5a1616e5ed45e8","name":"IUGR and IGF abnormalities","disease_group":"Endocrine disorders","disease_sub_group":"Growth hormone disorders","status":"public","version":"1.29","version_created":"2019-08-05T14:01:03.716110Z","relevant_disorders":[],"stats":{"number_of_genes":110,"number_of_strs":0,"number_of_regions":5},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"}]}},{"gene_data":{"alias":["ZNF698","bA145L22","bA145L22.2"],"biotype":"protein_coding","hgnc_id":"HGNC:18791","gene_name":"ZFP57 zinc finger protein","omim_gene":["612192"],"alias_name":null,"gene_symbol":"ZFP57","hgnc_symbol":"ZFP57","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"6:29640169-29648887","ensembl_id":"ENSG00000204644"}},"GRch38":{"90":{"location":"6:29672392-29681110","ensembl_id":"ENSG00000204644"}}},"hgnc_date_symbol_changed":"2005-07-20"},"entity_type":"gene","entity_name":"ZFP57","confidence_level":"3","penetrance":"Complete","mode_of_pathogenicity":"","publications":[],"evidence":["Expert Review Green","UKGTN","Illumina TruGenome Clinical Sequencing Services","Radboud University Medical Center, Nijmegen"],"phenotypes":["Diabetes mellitus, transient neonatal, 1, 601410","Transient Neonatal Diabetes, Recessive","Transient Neonatal Diabetes"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":26,"hash_id":"55a9238422c1fc6711b0c6c3","name":"Diabetes with additional phenotypes suggestive of a monogenic aetiology","disease_group":"Endocrine disorders","disease_sub_group":"Disorders of unusual phenotypes","status":"public","version":"1.59","version_created":"2019-06-20T15:15:00.936648Z","relevant_disorders":[],"stats":{"number_of_genes":64,"number_of_strs":0,"number_of_regions":1},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"}]}},{"gene_data":{"alias":["ZNF698","bA145L22","bA145L22.2"],"biotype":"protein_coding","hgnc_id":"HGNC:18791","gene_name":"ZFP57 zinc finger protein","omim_gene":["612192"],"alias_name":null,"gene_symbol":"ZFP57","hgnc_symbol":"ZFP57","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"6:29640169-29648887","ensembl_id":"ENSG00000204644"}},"GRch38":{"90":{"location":"6:29672392-29681110","ensembl_id":"ENSG00000204644"}}},"hgnc_date_symbol_changed":"2005-07-20"},"entity_type":"gene","entity_name":"ZFP57","confidence_level":"3","penetrance":"Complete","mode_of_pathogenicity":"","publications":["18622393"],"evidence":["NHS GMS","Expert Review Green","Eligibility statement prior genetic testing","UKGTN","Illumina TruGenome Clinical Sequencing Services","Radboud University Medical Center, Nijmegen"],"phenotypes":["Diabetes mellitus, transient neonatal, 1, 601410","Transient Neonatal Diabetes, Recessive","Transient Neonatal Diabetes"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":293,"hash_id":"55a9041e22c1fc6711b0c6c0","name":"Diabetes - neonatal onset","disease_group":"Endocrine disorders","disease_sub_group":"Disorders of unusual phenotypes","status":"public","version":"2.0","version_created":"2019-07-31T13:43:22.297175Z","relevant_disorders":["Neonatal diabetes (diagnosed less than 6 months)","Neonatal diabetes","Neonatal diabetes diagnosed <6 months","R143"],"stats":{"number_of_genes":33,"number_of_strs":0,"number_of_regions":1},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."},{"name":"GMS signed-off","slug":"gms-signed-off","description":"This panel has undergone review by a NHSE GMS disease specialist group and processes to be signed-off for use within the GMS."}]}},{"gene_data":{"alias":["ZNF698","bA145L22","bA145L22.2"],"biotype":"protein_coding","hgnc_id":"HGNC:18791","gene_name":"ZFP57 zinc finger protein","omim_gene":["612192"],"alias_name":null,"gene_symbol":"ZFP57","hgnc_symbol":"ZFP57","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"6:29640169-29648887","ensembl_id":"ENSG00000204644"}},"GRch38":{"90":{"location":"6:29672392-29681110","ensembl_id":"ENSG00000204644"}}},"hgnc_date_symbol_changed":"2005-07-20"},"entity_type":"gene","entity_name":"ZFP57","confidence_level":"3","penetrance":"Complete","mode_of_pathogenicity":"","publications":[],"evidence":["NHS GMS","Expert Review Green","UKGTN","Radboud University Medical Center, Nijmegen","Illumina TruGenome Clinical Sequencing Services"],"phenotypes":["Transient Neonatal Diabetes, Recessive","Diabetes mellitus, transient neonatal, 1, 601410"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":152,"hash_id":"553f9745bb5a1616e5ed45e9","name":"Familial diabetes","disease_group":"Endocrine disorders","disease_sub_group":"Disorders of unusual phenotypes","status":"public","version":"1.38","version_created":"2019-06-20T15:15:02.453936Z","relevant_disorders":["Familial young-onset non-insulin-dependent diabetes"],"stats":{"number_of_genes":56,"number_of_strs":0,"number_of_regions":1},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"}]}},{"gene_data":{"alias":["ZNF698","bA145L22","bA145L22.2"],"biotype":"protein_coding","hgnc_id":"HGNC:18791","gene_name":"ZFP57 zinc finger protein","omim_gene":["612192"],"alias_name":null,"gene_symbol":"ZFP57","hgnc_symbol":"ZFP57","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"6:29640169-29648887","ensembl_id":"ENSG00000204644"}},"GRch38":{"90":{"location":"6:29672392-29681110","ensembl_id":"ENSG00000204644"}}},"hgnc_date_symbol_changed":"2005-07-20"},"entity_type":"gene","entity_name":"ZFP57","confidence_level":"3","penetrance":null,"mode_of_pathogenicity":"","publications":[],"evidence":["NHS GMS","Expert Review Green"],"phenotypes":["Transient Neonatal Diabetes, Recessive","Diabetes mellitus, transient neonatal, 1, 601410","Transient Neonatal Diabetes"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":472,"hash_id":null,"name":"Monogenic diabetes","disease_group":"","disease_sub_group":"","status":"public","version":"2.1","version_created":"2019-07-31T13:20:07.800002Z","relevant_disorders":["R141"],"stats":{"number_of_genes":77,"number_of_strs":0,"number_of_regions":1},"types":[{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."},{"name":"GMS signed-off","slug":"gms-signed-off","description":"This panel has undergone review by a NHSE GMS disease specialist group and processes to be signed-off for use within the GMS."}]}},{"gene_data":{"alias":["ZNF698","bA145L22","bA145L22.2"],"biotype":"protein_coding","hgnc_id":"HGNC:18791","gene_name":"ZFP57 zinc finger protein","omim_gene":["612192"],"alias_name":null,"gene_symbol":"ZFP57","hgnc_symbol":"ZFP57","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"6:29640169-29648887","ensembl_id":"ENSG00000204644"}},"GRch38":{"90":{"location":"6:29672392-29681110","ensembl_id":"ENSG00000204644"}}},"hgnc_date_symbol_changed":"2005-07-20"},"entity_type":"gene","entity_name":"ZFP57","confidence_level":"3","penetrance":null,"mode_of_pathogenicity":"","publications":[],"evidence":["PAGE DD-Gene2Phenotype","Expert Review Green"],"phenotypes":["DIABETES MELLITUS, 6Q24-RELATED TRANSIENT NEONATAL"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":478,"hash_id":null,"name":"Fetal anomalies","disease_group":"","disease_sub_group":"","status":"public","version":"0.344","version_created":"2019-09-17T09:38:10.568007Z","relevant_disorders":["R21"],"stats":{"number_of_genes":1721,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."}]}},{"gene_data":{"alias":["ZNF698","bA145L22","bA145L22.2"],"biotype":"protein_coding","hgnc_id":"HGNC:18791","gene_name":"ZFP57 zinc finger protein","omim_gene":["612192"],"alias_name":null,"gene_symbol":"ZFP57","hgnc_symbol":"ZFP57","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"6:29640169-29648887","ensembl_id":"ENSG00000204644"}},"GRch38":{"90":{"location":"6:29672392-29681110","ensembl_id":"ENSG00000204644"}}},"hgnc_date_symbol_changed":"2005-07-20"},"entity_type":"gene","entity_name":"ZFP57","confidence_level":"3","penetrance":null,"mode_of_pathogenicity":"","publications":["18622393"],"evidence":["DD-Gene2Phenotype","Expert Review Green"],"phenotypes":["DIABETES MELLITUS, 6Q24-RELATED TRANSIENT NEONATAL 601410"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":484,"hash_id":null,"name":"DDG2P","disease_group":"","disease_sub_group":"","status":"public","version":"1.137","version_created":"2019-10-08T15:56:59.220133Z","relevant_disorders":[],"stats":{"number_of_genes":1893,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"GMS Rare Disease","slug":"gms-rare-disease","description":"This panel type is used for GMS panels that are not virtual (i.e. could be a wet lab test)"},{"name":"Component Of Super Panel","slug":"component-of-super-panel","description":"This panel is a component of a Super Panel"}]}},{"gene_data":{"alias":["ZNF698","bA145L22","bA145L22.2"],"biotype":"protein_coding","hgnc_id":"HGNC:18791","gene_name":"ZFP57 zinc finger protein","omim_gene":["612192"],"alias_name":null,"gene_symbol":"ZFP57","hgnc_symbol":"ZFP57","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"6:29640169-29648887","ensembl_id":"ENSG00000204644"}},"GRch38":{"90":{"location":"6:29672392-29681110","ensembl_id":"ENSG00000204644"}}},"hgnc_date_symbol_changed":"2005-07-20"},"entity_type":"gene","entity_name":"ZFP57","confidence_level":"1","penetrance":null,"mode_of_pathogenicity":"","publications":["PMID: 18622393"],"evidence":["Expert Review Red"],"phenotypes":["Phenotypes consistent with hypomethylation at multiple imprinted loci"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":473,"hash_id":null,"name":"Growth failure in early childhood","disease_group":"","disease_sub_group":"","status":"public","version":"1.3","version_created":"2019-08-14T09:11:49.488162Z","relevant_disorders":["R147"],"stats":{"number_of_genes":126,"number_of_strs":0,"number_of_regions":5},"types":[{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."},{"name":"GMS signed-off","slug":"gms-signed-off","description":"This panel has undergone review by a NHSE GMS disease specialist group and processes to be signed-off for use within the GMS."}]}},{"gene_data":{"alias":["ZNF698","bA145L22","bA145L22.2"],"biotype":"protein_coding","hgnc_id":"HGNC:18791","gene_name":"ZFP57 zinc finger protein","omim_gene":["612192"],"alias_name":null,"gene_symbol":"ZFP57","hgnc_symbol":"ZFP57","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"6:29640169-29648887","ensembl_id":"ENSG00000204644"}},"GRch38":{"90":{"location":"6:29672392-29681110","ensembl_id":"ENSG00000204644"}}},"hgnc_date_symbol_changed":"2005-07-20"},"entity_type":"gene","entity_name":"ZFP57","confidence_level":"2","penetrance":"Complete","mode_of_pathogenicity":"","publications":["23150280"],"evidence":["Victorian Clinical Genetics Services","Expert Review Amber","BRIDGE study SPEED NEURO Tier1 Gene"],"phenotypes":["Diabetes mellitus, transient neonatal, 1, 601410"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":285,"hash_id":"558aa423bb5a16630e15b63c","name":"Intellectual disability","disease_group":"Neurology and neurodevelopmental disorders","disease_sub_group":"Neurodevelopmental disorders","status":"public","version":"2.1065","version_created":"2019-10-07T13:42:16.019766Z","relevant_disorders":["Coarse facial features including Coffin-Siris-like disorders","ID","Moderate","severe or profound intellectual disability","Schizophrenia plus additional features","Intellectual disability - microarray","fragile X and sequencing"],"stats":{"number_of_genes":2253,"number_of_strs":11,"number_of_regions":57},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."},{"name":"Component Of Super Panel","slug":"component-of-super-panel","description":"This panel is a component of a Super Panel"}]}}]}