{"count":8,"next":null,"previous":null,"results":[{"gene_data":{"alias":["NF-E1","DELTA","UCRBP","YIN-YANG-1","INO80S"],"biotype":"protein_coding","hgnc_id":"HGNC:12856","gene_name":"YY1 transcription factor","omim_gene":["600013"],"alias_name":["INO80 complex subunit S","Yin and Yang 1 protein"],"gene_symbol":"YY1","hgnc_symbol":"YY1","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"14:100704635-100749129","ensembl_id":"ENSG00000100811"}},"GRch38":{"90":{"location":"14:100238298-100282792","ensembl_id":"ENSG00000100811"}}},"hgnc_date_symbol_changed":"1993-09-17"},"entity_type":"gene","entity_name":"YY1","confidence_level":"3","penetrance":"Complete","mode_of_pathogenicity":"","publications":["28575647"],"evidence":["Expert Review Green","Literature"],"phenotypes":["Gabriele-de Vries syndrome\t617557"],"mode_of_inheritance":"MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","tags":[],"panel":{"id":192,"hash_id":"553f95c9bb5a1616e5ed45bf","name":"Early onset dystonia","disease_group":"Neurology and neurodevelopmental disorders","disease_sub_group":"Motor Disorders of the CNS","status":"public","version":"1.81","version_created":"2019-09-23T11:22:14.418180Z","relevant_disorders":[],"stats":{"number_of_genes":111,"number_of_strs":4,"number_of_regions":0},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"}]}},{"gene_data":{"alias":["NF-E1","DELTA","UCRBP","YIN-YANG-1","INO80S"],"biotype":"protein_coding","hgnc_id":"HGNC:12856","gene_name":"YY1 transcription factor","omim_gene":["600013"],"alias_name":["INO80 complex subunit S","Yin and Yang 1 protein"],"gene_symbol":"YY1","hgnc_symbol":"YY1","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"14:100704635-100749129","ensembl_id":"ENSG00000100811"}},"GRch38":{"90":{"location":"14:100238298-100282792","ensembl_id":"ENSG00000100811"}}},"hgnc_date_symbol_changed":"1993-09-17"},"entity_type":"gene","entity_name":"YY1","confidence_level":"3","penetrance":null,"mode_of_pathogenicity":"","publications":["28575647"],"evidence":["Expert Review Green"],"phenotypes":["Gabriele-de Vries syndrome 617557"],"mode_of_inheritance":"MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","tags":[],"panel":{"id":475,"hash_id":null,"name":"Dystonia - childhood onset","disease_group":"","disease_sub_group":"","status":"public","version":"1.8","version_created":"2019-09-09T13:17:58.240159Z","relevant_disorders":[],"stats":{"number_of_genes":176,"number_of_strs":7,"number_of_regions":1},"types":[{"name":"GMS Rare Disease","slug":"gms-rare-disease","description":"This panel type is used for GMS panels that are not virtual (i.e. could be a wet lab test)"},{"name":"Component Of Super Panel","slug":"component-of-super-panel","description":"This panel is a component of a Super Panel"}]}},{"gene_data":{"alias":["NF-E1","DELTA","UCRBP","YIN-YANG-1","INO80S"],"biotype":"protein_coding","hgnc_id":"HGNC:12856","gene_name":"YY1 transcription factor","omim_gene":["600013"],"alias_name":["INO80 complex subunit S","Yin and Yang 1 protein"],"gene_symbol":"YY1","hgnc_symbol":"YY1","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"14:100704635-100749129","ensembl_id":"ENSG00000100811"}},"GRch38":{"90":{"location":"14:100238298-100282792","ensembl_id":"ENSG00000100811"}}},"hgnc_date_symbol_changed":"1993-09-17"},"entity_type":"gene","entity_name":"YY1","confidence_level":"3","penetrance":"Complete","mode_of_pathogenicity":"","publications":["28575647"],"evidence":["NHS GMS","Expert Review Green","Literature"],"phenotypes":["Gabriele-de Vries syndrome\t617557","Gabriele-de Vries syndrome 617557"],"mode_of_inheritance":"MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","tags":[],"panel":{"id":309,"hash_id":"5693952f22c1fc251660fb1e","name":"Skeletal dysplasia","disease_group":"Skeletal disorders","disease_sub_group":"Skeletal dysplasias","status":"public","version":"1.203","version_created":"2019-10-03T09:38:50.417968Z","relevant_disorders":["Unexplained skeletal dysplasia","Skeletal dysplasia"],"stats":{"number_of_genes":546,"number_of_strs":1,"number_of_regions":6},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."},{"name":"Component Of Super Panel","slug":"component-of-super-panel","description":"This panel is a component of a Super Panel"}]}},{"gene_data":{"alias":["NF-E1","DELTA","UCRBP","YIN-YANG-1","INO80S"],"biotype":"protein_coding","hgnc_id":"HGNC:12856","gene_name":"YY1 transcription factor","omim_gene":["600013"],"alias_name":["INO80 complex subunit S","Yin and Yang 1 protein"],"gene_symbol":"YY1","hgnc_symbol":"YY1","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"14:100704635-100749129","ensembl_id":"ENSG00000100811"}},"GRch38":{"90":{"location":"14:100238298-100282792","ensembl_id":"ENSG00000100811"}}},"hgnc_date_symbol_changed":"1993-09-17"},"entity_type":"gene","entity_name":"YY1","confidence_level":"1","penetrance":null,"mode_of_pathogenicity":"","publications":["28575647"],"evidence":["Expert Review Red","Wessex and West Midlands GLH","Yorkshire and North East GLH","NHS GMS","London North GLH"],"phenotypes":["Gabriele-de Vries syndrome 617557"],"mode_of_inheritance":"MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","tags":[],"panel":{"id":474,"hash_id":null,"name":"Neurodegenerative disorders - adult onset","disease_group":"","disease_sub_group":"","status":"public","version":"1.106","version_created":"2019-09-20T16:19:10.101841Z","relevant_disorders":["R58"],"stats":{"number_of_genes":395,"number_of_strs":18,"number_of_regions":4},"types":[{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."}]}},{"gene_data":{"alias":["NF-E1","DELTA","UCRBP","YIN-YANG-1","INO80S"],"biotype":"protein_coding","hgnc_id":"HGNC:12856","gene_name":"YY1 transcription factor","omim_gene":["600013"],"alias_name":["INO80 complex subunit S","Yin and Yang 1 protein"],"gene_symbol":"YY1","hgnc_symbol":"YY1","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"14:100704635-100749129","ensembl_id":"ENSG00000100811"}},"GRch38":{"90":{"location":"14:100238298-100282792","ensembl_id":"ENSG00000100811"}}},"hgnc_date_symbol_changed":"1993-09-17"},"entity_type":"gene","entity_name":"YY1","confidence_level":"3","penetrance":null,"mode_of_pathogenicity":"","publications":[],"evidence":["PAGE DD-Gene2Phenotype","Expert Review Green"],"phenotypes":["INTELLECTUAL DISABILITY"],"mode_of_inheritance":"MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown","tags":[],"panel":{"id":478,"hash_id":null,"name":"Fetal anomalies","disease_group":"","disease_sub_group":"","status":"public","version":"0.344","version_created":"2019-09-17T09:38:10.568007Z","relevant_disorders":["R21"],"stats":{"number_of_genes":1721,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."}]}},{"gene_data":{"alias":["NF-E1","DELTA","UCRBP","YIN-YANG-1","INO80S"],"biotype":"protein_coding","hgnc_id":"HGNC:12856","gene_name":"YY1 transcription factor","omim_gene":["600013"],"alias_name":["INO80 complex subunit S","Yin and Yang 1 protein"],"gene_symbol":"YY1","hgnc_symbol":"YY1","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"14:100704635-100749129","ensembl_id":"ENSG00000100811"}},"GRch38":{"90":{"location":"14:100238298-100282792","ensembl_id":"ENSG00000100811"}}},"hgnc_date_symbol_changed":"1993-09-17"},"entity_type":"gene","entity_name":"YY1","confidence_level":"3","penetrance":null,"mode_of_pathogenicity":"Other - please provide details in the comments","publications":["28575647","21076407"],"evidence":["DD-Gene2Phenotype","Expert Review Green"],"phenotypes":["INTELLECTUAL DISABILITY"],"mode_of_inheritance":"MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown","tags":[],"panel":{"id":484,"hash_id":null,"name":"DDG2P","disease_group":"","disease_sub_group":"","status":"public","version":"1.137","version_created":"2019-10-08T15:56:59.220133Z","relevant_disorders":[],"stats":{"number_of_genes":1893,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"GMS Rare Disease","slug":"gms-rare-disease","description":"This panel type is used for GMS panels that are not virtual (i.e. could be a wet lab test)"},{"name":"Component Of Super Panel","slug":"component-of-super-panel","description":"This panel is a component of a Super Panel"}]}},{"gene_data":{"alias":["NF-E1","DELTA","UCRBP","YIN-YANG-1","INO80S"],"biotype":"protein_coding","hgnc_id":"HGNC:12856","gene_name":"YY1 transcription factor","omim_gene":["600013"],"alias_name":["INO80 complex subunit S","Yin and Yang 1 protein"],"gene_symbol":"YY1","hgnc_symbol":"YY1","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"14:100704635-100749129","ensembl_id":"ENSG00000100811"}},"GRch38":{"90":{"location":"14:100238298-100282792","ensembl_id":"ENSG00000100811"}}},"hgnc_date_symbol_changed":"1993-09-17"},"entity_type":"gene","entity_name":"YY1","confidence_level":"3","penetrance":"Complete","mode_of_pathogenicity":"","publications":["21076407","28575647"],"evidence":["Victorian Clinical Genetics Services","Expert Review Green"],"phenotypes":["Gabriele-de Vries syndrome\t617557"],"mode_of_inheritance":"MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","tags":[],"panel":{"id":285,"hash_id":"558aa423bb5a16630e15b63c","name":"Intellectual disability","disease_group":"Neurology and neurodevelopmental disorders","disease_sub_group":"Neurodevelopmental disorders","status":"public","version":"2.1065","version_created":"2019-10-07T13:42:16.019766Z","relevant_disorders":["Coarse facial features including Coffin-Siris-like disorders","ID","Moderate","severe or profound intellectual disability","Schizophrenia plus additional features","Intellectual disability - microarray","fragile X and sequencing"],"stats":{"number_of_genes":2253,"number_of_strs":11,"number_of_regions":57},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."},{"name":"Component Of Super Panel","slug":"component-of-super-panel","description":"This panel is a component of a Super Panel"}]}},{"gene_data":{"alias":["NF-E1","DELTA","UCRBP","YIN-YANG-1","INO80S"],"biotype":"protein_coding","hgnc_id":"HGNC:12856","gene_name":"YY1 transcription factor","omim_gene":["600013"],"alias_name":["INO80 complex subunit S","Yin and Yang 1 protein"],"gene_symbol":"YY1","hgnc_symbol":"YY1","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"14:100704635-100749129","ensembl_id":"ENSG00000100811"}},"GRch38":{"90":{"location":"14:100238298-100282792","ensembl_id":"ENSG00000100811"}}},"hgnc_date_symbol_changed":"1993-09-17"},"entity_type":"gene","entity_name":"YY1","confidence_level":"2","penetrance":null,"mode_of_pathogenicity":"","publications":["28575647"],"evidence":["Expert Review Amber","NHS GMS","London North GLH"],"phenotypes":["Gabriele-de Vries syndrome"],"mode_of_inheritance":"MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","tags":[],"panel":{"id":540,"hash_id":null,"name":"Adult onset movement disorder","disease_group":"","disease_sub_group":"","status":"public","version":"0.125","version_created":"2019-09-29T14:25:05.513850Z","relevant_disorders":["R56"],"stats":{"number_of_genes":202,"number_of_strs":11,"number_of_regions":1},"types":[{"name":"GMS Rare Disease","slug":"gms-rare-disease","description":"This panel type is used for GMS panels that are not virtual (i.e. could be a wet lab test)"}]}}]}
