{"count":1,"next":null,"previous":null,"results":[{"gene_data":{"alias":["YTS","YRS","tyrRS"],"biotype":"protein_coding","hgnc_id":"HGNC:12840","gene_name":"tyrosyl-tRNA synthetase","omim_gene":["603623"],"alias_name":["tyrosine tRNA ligase 1, cytoplasmic"],"gene_symbol":"YARS","hgnc_symbol":"YARS","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"1:33240840-33283754","ensembl_id":"ENSG00000134684"}},"GRch38":{"90":{"location":"1:32775237-32818153","ensembl_id":"ENSG00000134684"}}},"hgnc_date_symbol_changed":"1999-01-29"},"entity_type":"gene","entity_name":"YARS","confidence_level":"3","penetrance":"Complete","mode_of_pathogenicity":"","publications":["16429158","19561293"],"evidence":["South West GLH","NHS GMS","London North GLH","Expert Review Green","Emory Genetics Laboratory","UKGTN","Expert list","Radboud University Medical Center, Nijmegen","Illumina TruGenome Clinical Sequencing Services"],"phenotypes":["Charcot Marie Tooth disease, dominant intermediate C, 608323","Charcot Marie Tooth disease, dominant intermediate C, 608323"],"mode_of_inheritance":"MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown","tags":[],"panel":{"id":85,"hash_id":"55ad205422c1fc7041340234","name":"Hereditary neuropathy","disease_group":"Neurology and neurodevelopmental disorders","disease_sub_group":"Motor and Sensory Disorders of the PNS","status":"public","version":"1.333","version_created":"2019-07-09T13:10:50.031506Z","relevant_disorders":["Charcot-Marie-Tooth disease"],"stats":{"number_of_genes":276,"number_of_strs":11,"number_of_regions":2},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."}]}}]}