{"count":9,"next":null,"previous":null,"results":[{"gene_data":{"alias":["FOR","WOX1","SDR41C1"],"biotype":"protein_coding","hgnc_id":"HGNC:12799","gene_name":"WW domain containing oxidoreductase","omim_gene":["605131"],"alias_name":["short chain dehydrogenase/reductase family 41C, member 1"],"gene_symbol":"WWOX","hgnc_symbol":"WWOX","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"16:78133310-79246564","ensembl_id":"ENSG00000186153"}},"GRch38":{"90":{"location":"16:78099413-79212667","ensembl_id":"ENSG00000186153"}}},"hgnc_date_symbol_changed":"2000-07-31"},"entity_type":"gene","entity_name":"WWOX","confidence_level":"3","penetrance":null,"mode_of_pathogenicity":"","publications":[],"evidence":["Expert Review Green"],"phenotypes":["Autosomal recessive spinocerebellar ataxia 12, 614322"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":477,"hash_id":null,"name":"Ataxia and cerebellar anomalies - narrow panel","disease_group":"","disease_sub_group":"","status":"public","version":"1.7","version_created":"2019-09-20T16:56:48.672242Z","relevant_disorders":[],"stats":{"number_of_genes":199,"number_of_strs":13,"number_of_regions":3},"types":[{"name":"GMS Rare Disease","slug":"gms-rare-disease","description":"This panel type is used for GMS panels that are not virtual (i.e. could be a wet lab test)"},{"name":"Component Of Super Panel","slug":"component-of-super-panel","description":"This panel is a component of a Super Panel"}]}},{"gene_data":{"alias":["FOR","WOX1","SDR41C1"],"biotype":"protein_coding","hgnc_id":"HGNC:12799","gene_name":"WW domain containing oxidoreductase","omim_gene":["605131"],"alias_name":["short chain dehydrogenase/reductase family 41C, member 1"],"gene_symbol":"WWOX","hgnc_symbol":"WWOX","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"16:78133310-79246564","ensembl_id":"ENSG00000186153"}},"GRch38":{"90":{"location":"16:78099413-79212667","ensembl_id":"ENSG00000186153"}}},"hgnc_date_symbol_changed":"2000-07-31"},"entity_type":"gene","entity_name":"WWOX","confidence_level":"3","penetrance":"Complete","mode_of_pathogenicity":"","publications":[],"evidence":["Expert Review Green","Expert Review"],"phenotypes":["Autosomal recessive spinocerebellar ataxia 12, 614322"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":20,"hash_id":"559a7d1022c1fc58ad67fc97","name":"Hereditary ataxia","disease_group":"Neurology and neurodevelopmental disorders","disease_sub_group":"Motor Disorders of the CNS","status":"public","version":"1.202","version_created":"2019-06-20T15:15:07.878228Z","relevant_disorders":[],"stats":{"number_of_genes":160,"number_of_strs":14,"number_of_regions":3},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"}]}},{"gene_data":{"alias":["FOR","WOX1","SDR41C1"],"biotype":"protein_coding","hgnc_id":"HGNC:12799","gene_name":"WW domain containing oxidoreductase","omim_gene":["605131"],"alias_name":["short chain dehydrogenase/reductase family 41C, member 1"],"gene_symbol":"WWOX","hgnc_symbol":"WWOX","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"16:78133310-79246564","ensembl_id":"ENSG00000186153"}},"GRch38":{"90":{"location":"16:78099413-79212667","ensembl_id":"ENSG00000186153"}}},"hgnc_date_symbol_changed":"2000-07-31"},"entity_type":"gene","entity_name":"WWOX","confidence_level":"1","penetrance":null,"mode_of_pathogenicity":"","publications":[],"evidence":["Expert Review Red","SFARI"],"phenotypes":[],"mode_of_inheritance":"","tags":[],"panel":{"id":657,"hash_id":null,"name":"Autism","disease_group":"","disease_sub_group":"","status":"public","version":"0.15","version_created":"2019-06-20T15:10:14.437740Z","relevant_disorders":[],"stats":{"number_of_genes":733,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"Research","slug":"research","description":"This is a gene panel used for research."}]}},{"gene_data":{"alias":["FOR","WOX1","SDR41C1"],"biotype":"protein_coding","hgnc_id":"HGNC:12799","gene_name":"WW domain containing oxidoreductase","omim_gene":["605131"],"alias_name":["short chain dehydrogenase/reductase family 41C, member 1"],"gene_symbol":"WWOX","hgnc_symbol":"WWOX","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"16:78133310-79246564","ensembl_id":"ENSG00000186153"}},"GRch38":{"90":{"location":"16:78099413-79212667","ensembl_id":"ENSG00000186153"}}},"hgnc_date_symbol_changed":"2000-07-31"},"entity_type":"gene","entity_name":"WWOX","confidence_level":"1","penetrance":null,"mode_of_pathogenicity":"","publications":[],"evidence":["Expert Review Red","Wessex and West Midlands GLH","Yorkshire and North East GLH","NHS GMS","London North GLH"],"phenotypes":["Autosomal recessive spinocerebellar ataxia 12, 614322"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":474,"hash_id":null,"name":"Neurodegenerative disorders - adult onset","disease_group":"","disease_sub_group":"","status":"public","version":"1.106","version_created":"2019-09-20T16:19:10.101841Z","relevant_disorders":["R58"],"stats":{"number_of_genes":395,"number_of_strs":18,"number_of_regions":4},"types":[{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."}]}},{"gene_data":{"alias":["FOR","WOX1","SDR41C1"],"biotype":"protein_coding","hgnc_id":"HGNC:12799","gene_name":"WW domain containing oxidoreductase","omim_gene":["605131"],"alias_name":["short chain dehydrogenase/reductase family 41C, member 1"],"gene_symbol":"WWOX","hgnc_symbol":"WWOX","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"16:78133310-79246564","ensembl_id":"ENSG00000186153"}},"GRch38":{"90":{"location":"16:78099413-79212667","ensembl_id":"ENSG00000186153"}}},"hgnc_date_symbol_changed":"2000-07-31"},"entity_type":"gene","entity_name":"WWOX","confidence_level":"2","penetrance":null,"mode_of_pathogenicity":"","publications":[],"evidence":["Expert Review Amber","PAGE DD-Gene2Phenotype"],"phenotypes":["EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 28","SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE 12"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":478,"hash_id":null,"name":"Fetal anomalies","disease_group":"","disease_sub_group":"","status":"public","version":"0.344","version_created":"2019-09-17T09:38:10.568007Z","relevant_disorders":["R21"],"stats":{"number_of_genes":1721,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."}]}},{"gene_data":{"alias":["FOR","WOX1","SDR41C1"],"biotype":"protein_coding","hgnc_id":"HGNC:12799","gene_name":"WW domain containing oxidoreductase","omim_gene":["605131"],"alias_name":["short chain dehydrogenase/reductase family 41C, member 1"],"gene_symbol":"WWOX","hgnc_symbol":"WWOX","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"16:78133310-79246564","ensembl_id":"ENSG00000186153"}},"GRch38":{"90":{"location":"16:78099413-79212667","ensembl_id":"ENSG00000186153"}}},"hgnc_date_symbol_changed":"2000-07-31"},"entity_type":"gene","entity_name":"WWOX","confidence_level":"2","penetrance":null,"mode_of_pathogenicity":"","publications":["24456803"],"evidence":["DD-Gene2Phenotype","Expert Review Amber"],"phenotypes":["SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE 12 614322","EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 28 616211"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":484,"hash_id":null,"name":"DDG2P","disease_group":"","disease_sub_group":"","status":"public","version":"1.137","version_created":"2019-10-08T15:56:59.220133Z","relevant_disorders":[],"stats":{"number_of_genes":1893,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"GMS Rare Disease","slug":"gms-rare-disease","description":"This panel type is used for GMS panels that are not virtual (i.e. could be a wet lab test)"},{"name":"Component Of Super Panel","slug":"component-of-super-panel","description":"This panel is a component of a Super Panel"}]}},{"gene_data":{"alias":["FOR","WOX1","SDR41C1"],"biotype":"protein_coding","hgnc_id":"HGNC:12799","gene_name":"WW domain containing oxidoreductase","omim_gene":["605131"],"alias_name":["short chain dehydrogenase/reductase family 41C, member 1"],"gene_symbol":"WWOX","hgnc_symbol":"WWOX","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"16:78133310-79246564","ensembl_id":"ENSG00000186153"}},"GRch38":{"90":{"location":"16:78099413-79212667","ensembl_id":"ENSG00000186153"}}},"hgnc_date_symbol_changed":"2000-07-31"},"entity_type":"gene","entity_name":"WWOX","confidence_level":"3","penetrance":null,"mode_of_pathogenicity":null,"publications":["Tabarki (2015) Ben-Salam (2015) Mignot (2015)"],"evidence":["Wessex and West Midlands GLH","NHS GMS","Victorian Clinical Genetics Services","Expert Review Green","Expert Review"],"phenotypes":[],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":402,"hash_id":null,"name":"Genetic epilepsy syndromes","disease_group":"Neurology and neurodevelopmental disorders","disease_sub_group":"Inherited Epilepsy Syndromes","status":"public","version":"1.363","version_created":"2019-10-08T10:06:11.607307Z","relevant_disorders":["Epilepsy Plus","Epilepsy plus other features","Genetic Epilepsy Syndromes","Epileptic encephalopathy","Familial Focal Epilepsies","Familial Genetic Generalised Epilepsies","Genetic Epilepsies with Febrile Seizures Plus (GEFS+)","Genetic Epilepsies with Febrile Seizures Plus"],"stats":{"number_of_genes":614,"number_of_strs":2,"number_of_regions":13},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease","slug":"gms-rare-disease","description":"This panel type is used for GMS panels that are not virtual (i.e. could be a wet lab test)"},{"name":"Component Of Super Panel","slug":"component-of-super-panel","description":"This panel is a component of a Super Panel"}]}},{"gene_data":{"alias":["FOR","WOX1","SDR41C1"],"biotype":"protein_coding","hgnc_id":"HGNC:12799","gene_name":"WW domain containing oxidoreductase","omim_gene":["605131"],"alias_name":["short chain dehydrogenase/reductase family 41C, member 1"],"gene_symbol":"WWOX","hgnc_symbol":"WWOX","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"16:78133310-79246564","ensembl_id":"ENSG00000186153"}},"GRch38":{"90":{"location":"16:78099413-79212667","ensembl_id":"ENSG00000186153"}}},"hgnc_date_symbol_changed":"2000-07-31"},"entity_type":"gene","entity_name":"WWOX","confidence_level":"3","penetrance":"Complete","mode_of_pathogenicity":"","publications":["24456803"],"evidence":["Victorian Clinical Genetics Services","Expert Review Green"],"phenotypes":["SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE 12"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":285,"hash_id":"558aa423bb5a16630e15b63c","name":"Intellectual disability","disease_group":"Neurology and neurodevelopmental disorders","disease_sub_group":"Neurodevelopmental disorders","status":"public","version":"2.1065","version_created":"2019-10-07T13:42:16.019766Z","relevant_disorders":["Coarse facial features including Coffin-Siris-like disorders","ID","Moderate","severe or profound intellectual disability","Schizophrenia plus additional features","Intellectual disability - microarray","fragile X and sequencing"],"stats":{"number_of_genes":2253,"number_of_strs":11,"number_of_regions":57},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."},{"name":"Component Of Super Panel","slug":"component-of-super-panel","description":"This panel is a component of a Super Panel"}]}},{"gene_data":{"alias":["FOR","WOX1","SDR41C1"],"biotype":"protein_coding","hgnc_id":"HGNC:12799","gene_name":"WW domain containing oxidoreductase","omim_gene":["605131"],"alias_name":["short chain dehydrogenase/reductase family 41C, member 1"],"gene_symbol":"WWOX","hgnc_symbol":"WWOX","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"16:78133310-79246564","ensembl_id":"ENSG00000186153"}},"GRch38":{"90":{"location":"16:78099413-79212667","ensembl_id":"ENSG00000186153"}}},"hgnc_date_symbol_changed":"2000-07-31"},"entity_type":"gene","entity_name":"WWOX","confidence_level":"3","penetrance":null,"mode_of_pathogenicity":"","publications":[],"evidence":["NHS GMS","Wessex and West Midlands GLH","Expert Review Green","Hereditary ataxia v1.148"],"phenotypes":["Autosomal recessive spinocerebellar ataxia 12, 6143232","Autosomal recessive spinocerebellar ataxia 12, 614322","Early infantile epileptic encephalopathy 28, 616211"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":466,"hash_id":null,"name":"Hereditary ataxia - adult onset","disease_group":"","disease_sub_group":"","status":"public","version":"1.211","version_created":"2019-09-20T14:18:40.957460Z","relevant_disorders":["Hereditary ataxia with onset in adulthood","R54"],"stats":{"number_of_genes":236,"number_of_strs":13,"number_of_regions":4},"types":[{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."}]}}]}
