{"count":4,"next":null,"previous":null,"results":[{"gene_data":{"alias":["VAP-B","VAP-C","ALS8"],"biotype":"protein_coding","hgnc_id":"HGNC:12649","gene_name":"VAMP associated protein B and C","omim_gene":["605704"],"alias_name":null,"gene_symbol":"VAPB","hgnc_symbol":"VAPB","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"20:56964178-57026157","ensembl_id":"ENSG00000124164"}},"GRch38":{"90":{"location":"20:58389122-58451101","ensembl_id":"ENSG00000124164"}}},"hgnc_date_symbol_changed":"1999-03-19"},"entity_type":"gene","entity_name":"VAPB","confidence_level":"2","penetrance":null,"mode_of_pathogenicity":"","publications":["15372378"],"evidence":["Expert Review Amber"],"phenotypes":["Amyotrophic lateral sclerosis 8 608627","Spinal muscular atrophy, late-onset, Finkel type 182980"],"mode_of_inheritance":"MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown","tags":[],"panel":{"id":465,"hash_id":null,"name":"Neuromuscular disorders","disease_group":"","disease_sub_group":"","status":"public","version":"1.11","version_created":"2019-10-09T12:42:27.875560Z","relevant_disorders":["Other rare neuromuscular disorders; R381"],"stats":{"number_of_genes":245,"number_of_strs":2,"number_of_regions":5},"types":[{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."},{"name":"Component Of Super Panel","slug":"component-of-super-panel","description":"This panel is a component of a Super Panel"}]}},{"gene_data":{"alias":["VAP-B","VAP-C","ALS8"],"biotype":"protein_coding","hgnc_id":"HGNC:12649","gene_name":"VAMP associated protein B and C","omim_gene":["605704"],"alias_name":null,"gene_symbol":"VAPB","hgnc_symbol":"VAPB","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"20:56964178-57026157","ensembl_id":"ENSG00000124164"}},"GRch38":{"90":{"location":"20:58389122-58451101","ensembl_id":"ENSG00000124164"}}},"hgnc_date_symbol_changed":"1999-03-19"},"entity_type":"gene","entity_name":"VAPB","confidence_level":"3","penetrance":null,"mode_of_pathogenicity":"","publications":["18555774","15372378"],"evidence":["Wessex and West Midlands GLH","Yorkshire and North East GLH","NHS GMS","London North GLH","Expert Review Green"],"phenotypes":["Amyotrophic lateral sclerosis 8, 608627","Amyotrophic Lateral Sclerosis, Dominant"],"mode_of_inheritance":"MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown","tags":[],"panel":{"id":474,"hash_id":null,"name":"Neurodegenerative disorders - adult onset","disease_group":"","disease_sub_group":"","status":"public","version":"1.106","version_created":"2019-09-20T16:19:10.101841Z","relevant_disorders":["R58"],"stats":{"number_of_genes":395,"number_of_strs":18,"number_of_regions":4},"types":[{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."}]}},{"gene_data":{"alias":["VAP-B","VAP-C","ALS8"],"biotype":"protein_coding","hgnc_id":"HGNC:12649","gene_name":"VAMP associated protein B and C","omim_gene":["605704"],"alias_name":null,"gene_symbol":"VAPB","hgnc_symbol":"VAPB","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"20:56964178-57026157","ensembl_id":"ENSG00000124164"}},"GRch38":{"90":{"location":"20:58389122-58451101","ensembl_id":"ENSG00000124164"}}},"hgnc_date_symbol_changed":"1999-03-19"},"entity_type":"gene","entity_name":"VAPB","confidence_level":"3","penetrance":"Complete","mode_of_pathogenicity":"","publications":[],"evidence":["Expert Review Green","Radboud University Medical Center, Nijmegen","Illumina TruGenome Clinical Sequencing Services"],"phenotypes":["Amyotrophic Lateral Sclerosis, Dominant","Amyotrophic lateral sclerosis 8, 608627"],"mode_of_inheritance":"MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown","tags":[],"panel":{"id":263,"hash_id":"55d30b0322c1fc2ff2a5bf7b","name":"Amyotrophic lateral sclerosis/motor neuron disease","disease_group":"Neurology and neurodevelopmental disorders","disease_sub_group":"Neurodegenerative disorders","status":"public","version":"1.29","version_created":"2019-06-20T15:14:55.521778Z","relevant_disorders":["Amyotrophic lateral sclerosis or motor neuron disease"],"stats":{"number_of_genes":30,"number_of_strs":4,"number_of_regions":0},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"}]}},{"gene_data":{"alias":["VAP-B","VAP-C","ALS8"],"biotype":"protein_coding","hgnc_id":"HGNC:12649","gene_name":"VAMP associated protein B and C","omim_gene":["605704"],"alias_name":null,"gene_symbol":"VAPB","hgnc_symbol":"VAPB","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"20:56964178-57026157","ensembl_id":"ENSG00000124164"}},"GRch38":{"90":{"location":"20:58389122-58451101","ensembl_id":"ENSG00000124164"}}},"hgnc_date_symbol_changed":"1999-03-19"},"entity_type":"gene","entity_name":"VAPB","confidence_level":"2","penetrance":"Complete","mode_of_pathogenicity":"","publications":["15372378"],"evidence":["Expert Review Amber","Radboud University Medical Center, Nijmegen","Illumina TruGenome Clinical Sequencing Services"],"phenotypes":["Spinal muscular atrophy, late-onset, Finkel type 182980","Amyotrophic lateral sclerosis 8 608627"],"mode_of_inheritance":"MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown","tags":[],"panel":{"id":79,"hash_id":"5541ef3dbb5a160c33b964e0","name":"Paediatric motor neuronopathies","disease_group":"Neurology and neurodevelopmental disorders","disease_sub_group":"Motor and Sensory Disorders of the PNS","status":"public","version":"1.23","version_created":"2019-06-20T15:15:14.703422Z","relevant_disorders":[],"stats":{"number_of_genes":39,"number_of_strs":1,"number_of_regions":5},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."}]}}]}
