{"count":1,"next":null,"previous":null,"results":[{"gene_data":{"alias":[],"biotype":"protein_coding","hgnc_id":"HGNC:12019","gene_name":"tryptase alpha/beta 1","omim_gene":["191080"],"alias_name":["tryptase alpha II","tryptase beta I","tryptase-I","tryptase-II","tryptase-III"],"gene_symbol":"TPSAB1","hgnc_symbol":"TPSAB1","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"16:1290697-1292555","ensembl_id":"ENSG00000172236"}},"GRch38":{"90":{"location":"16:1240696-1242554","ensembl_id":"ENSG00000172236"}}},"hgnc_date_symbol_changed":"2004-10-15"},"entity_type":"gene","entity_name":"TPSAB1","confidence_level":"1","penetrance":"Complete","mode_of_pathogenicity":"","publications":["27749843"],"evidence":["Expert Review","Literature"],"phenotypes":["?Mast cell dysfunction (with joint hypermobility)"],"mode_of_inheritance":"Unknown","tags":[],"panel":{"id":53,"hash_id":"588728f38f62030cf7152165","name":"Ehlers Danlos syndromes","disease_group":"Rheumatological disorders","disease_sub_group":"Connective tissues disorders","status":"public","version":"2.1","version_created":"2019-10-09T07:04:44.655768Z","relevant_disorders":["Classical Ehlers Danlos Syndrome","Classical Ehlers-Danlos Syndrome","Ehlers-Danlos Syndrome (unusual phenotypes e.g. absent pain sense)","Ehlers-Danlos syndrome type 3","Kyphoscoliotic Ehlers-Danlos syndrome","EDS","Ehlers-Danlos syndromes","R101"],"stats":{"number_of_genes":75,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease","slug":"gms-rare-disease","description":"This panel type is used for GMS panels that are not virtual (i.e. could be a wet lab test)"},{"name":"GMS signed-off","slug":"gms-signed-off","description":"This panel has undergone review by a NHSE GMS disease specialist group and processes to be signed-off for use within the GMS."}]}}]}