{"count":2,"next":null,"previous":null,"results":[{"gene_data":{"alias":["dj747L4.1","TPIT"],"biotype":"protein_coding","hgnc_id":"HGNC:11596","gene_name":"T-box 19","omim_gene":["604614"],"alias_name":["TBS 19"],"gene_symbol":"TBX19","hgnc_symbol":"TBX19","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"1:168250278-168283664","ensembl_id":"ENSG00000143178"}},"GRch38":{"90":{"location":"1:168281040-168314426","ensembl_id":"ENSG00000143178"}}},"hgnc_date_symbol_changed":"1999-02-01"},"entity_type":"gene","entity_name":"TBX19","confidence_level":"3","penetrance":"Complete","mode_of_pathogenicity":"","publications":["16390921 (TPIT)","15613420 (TPIT)","15525497 (TPIT)"],"evidence":["Expert Review Green","Expert list"],"phenotypes":["Isolated ACTH insufficiency","Adrenocorticotropic hormone deficiency \t201400"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":145,"hash_id":"55bf785822c1fc0fe45530bf","name":"Congenital adrenal hypoplasia","disease_group":"Endocrine disorders","disease_sub_group":"Adrenal disorders","status":"public","version":"2.0","version_created":"2019-07-31T14:08:52.172447Z","relevant_disorders":["R150"],"stats":{"number_of_genes":20,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."},{"name":"GMS signed-off","slug":"gms-signed-off","description":"This panel has undergone review by a NHSE GMS disease specialist group and processes to be signed-off for use within the GMS."}]}},{"gene_data":{"alias":["dj747L4.1","TPIT"],"biotype":"protein_coding","hgnc_id":"HGNC:11596","gene_name":"T-box 19","omim_gene":["604614"],"alias_name":["TBS 19"],"gene_symbol":"TBX19","hgnc_symbol":"TBX19","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"1:168250278-168283664","ensembl_id":"ENSG00000143178"}},"GRch38":{"90":{"location":"1:168281040-168314426","ensembl_id":"ENSG00000143178"}}},"hgnc_date_symbol_changed":"1999-02-01"},"entity_type":"gene","entity_name":"TBX19","confidence_level":"3","penetrance":null,"mode_of_pathogenicity":"","publications":["11290323","15476446","22170728"],"evidence":["Expert Review Green","Literature","Illumina TruGenome Clinical Sequencing Services","Radboud University Medical Center, Nijmegen"],"phenotypes":["Adrenocorticotropic hormone deficiency (201400)"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":483,"hash_id":null,"name":"Pituitary hormone deficiency","disease_group":"","disease_sub_group":"","status":"public","version":"2.0","version_created":"2019-07-31T14:30:21.964840Z","relevant_disorders":["R159"],"stats":{"number_of_genes":50,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."},{"name":"GMS signed-off","slug":"gms-signed-off","description":"This panel has undergone review by a NHSE GMS disease specialist group and processes to be signed-off for use within the GMS."}]}}]}
