{"count":5,"next":null,"previous":null,"results":[{"gene_data":{"alias":["HsRad51","HsT16930","BRCC5","FANCR"],"biotype":"protein_coding","hgnc_id":"HGNC:9817","gene_name":"RAD51 recombinase","omim_gene":["179617"],"alias_name":["BRCA1/BRCA2-containing complex, subunit 5"],"gene_symbol":"RAD51","hgnc_symbol":"RAD51","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"15:40986972-41024354","ensembl_id":"ENSG00000051180"}},"GRch38":{"90":{"location":"15:40694774-40732339","ensembl_id":"ENSG00000051180"}}},"hgnc_date_symbol_changed":"1993-05-26"},"entity_type":"gene","entity_name":"RAD51","confidence_level":"2","penetrance":null,"mode_of_pathogenicity":null,"publications":["28297620"],"evidence":["Expert Review Amber","Curated sources","Expert Review Amber"],"phenotypes":["Class: BM failure FA, (typ AR)","Fanconi anemia","MDS","AML","Squamous cell carcinoma: oral, GI, vulvar"],"mode_of_inheritance":"MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown","tags":[],"panel":{"id":407,"hash_id":null,"name":"Haematological malignancies for rare disease","disease_group":"Tumour syndromes","disease_sub_group":"Tumour syndromes","status":"public","version":"1.1","version_created":"2019-06-20T15:11:49.421852Z","relevant_disorders":[],"stats":{"number_of_genes":89,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"}]}},{"gene_data":{"alias":["HsRad51","HsT16930","BRCC5","FANCR"],"biotype":"protein_coding","hgnc_id":"HGNC:9817","gene_name":"RAD51 recombinase","omim_gene":["179617"],"alias_name":["BRCA1/BRCA2-containing complex, subunit 5"],"gene_symbol":"RAD51","hgnc_symbol":"RAD51","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"15:40986972-41024354","ensembl_id":"ENSG00000051180"}},"GRch38":{"90":{"location":"15:40694774-40732339","ensembl_id":"ENSG00000051180"}}},"hgnc_date_symbol_changed":"1993-05-26"},"entity_type":"gene","entity_name":"RAD51","confidence_level":"2","penetrance":"Complete","mode_of_pathogenicity":"","publications":["28297620"],"evidence":["Expert Review Amber","Curated sources"],"phenotypes":["Class: BM failure FA, (typ AR)","Fanconi anemia","MDS","AML","Squamous cell carcinoma: oral, GI, vulvar"],"mode_of_inheritance":"MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown","tags":[],"panel":{"id":59,"hash_id":"594a71908f620375d17ea6b2","name":"Haematological malignancies cancer susceptibility","disease_group":"Cancer Programme","disease_sub_group":"Pertinent cancer susceptibility gene panel","status":"public","version":"1.19","version_created":"2019-08-06T10:21:26.792978Z","relevant_disorders":["Haemonc;Haematological malignancies pertinent cancer susceptibility"],"stats":{"number_of_genes":93,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"Cancer Germline 100K","slug":"cancer-germline-100k","description":"Cancer Germline 100K"},{"name":"GMS Cancer Germline Virtual","slug":"gms-cancer-germline-virtual","description":"This is a panel used for WGS germline analysis for the GMS."}]}},{"gene_data":{"alias":["HsRad51","HsT16930","BRCC5","FANCR"],"biotype":"protein_coding","hgnc_id":"HGNC:9817","gene_name":"RAD51 recombinase","omim_gene":["179617"],"alias_name":["BRCA1/BRCA2-containing complex, subunit 5"],"gene_symbol":"RAD51","hgnc_symbol":"RAD51","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"15:40986972-41024354","ensembl_id":"ENSG00000051180"}},"GRch38":{"90":{"location":"15:40694774-40732339","ensembl_id":"ENSG00000051180"}}},"hgnc_date_symbol_changed":"1993-05-26"},"entity_type":"gene","entity_name":"RAD51","confidence_level":"2","penetrance":null,"mode_of_pathogenicity":"","publications":[],"evidence":["Expert Review Amber","PAGE DD-Gene2Phenotype"],"phenotypes":["MIRROR MOVEMENTS 2"],"mode_of_inheritance":"MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown","tags":[],"panel":{"id":478,"hash_id":null,"name":"Fetal anomalies","disease_group":"","disease_sub_group":"","status":"public","version":"0.344","version_created":"2019-09-17T09:38:10.568007Z","relevant_disorders":["R21"],"stats":{"number_of_genes":1721,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."}]}},{"gene_data":{"alias":["HsRad51","HsT16930","BRCC5","FANCR"],"biotype":"protein_coding","hgnc_id":"HGNC:9817","gene_name":"RAD51 recombinase","omim_gene":["179617"],"alias_name":["BRCA1/BRCA2-containing complex, subunit 5"],"gene_symbol":"RAD51","hgnc_symbol":"RAD51","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"15:40986972-41024354","ensembl_id":"ENSG00000051180"}},"GRch38":{"90":{"location":"15:40694774-40732339","ensembl_id":"ENSG00000051180"}}},"hgnc_date_symbol_changed":"1993-05-26"},"entity_type":"gene","entity_name":"RAD51","confidence_level":"1","penetrance":null,"mode_of_pathogenicity":"","publications":["21242494"],"evidence":["Expert Review Red","DD-Gene2Phenotype"],"phenotypes":["MIRROR MOVEMENTS 2 614508"],"mode_of_inheritance":"MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown","tags":[],"panel":{"id":484,"hash_id":null,"name":"DDG2P","disease_group":"","disease_sub_group":"","status":"public","version":"1.137","version_created":"2019-10-08T15:56:59.220133Z","relevant_disorders":[],"stats":{"number_of_genes":1893,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"GMS Rare Disease","slug":"gms-rare-disease","description":"This panel type is used for GMS panels that are not virtual (i.e. could be a wet lab test)"},{"name":"Component Of Super Panel","slug":"component-of-super-panel","description":"This panel is a component of a Super Panel"}]}},{"gene_data":{"alias":["HsRad51","HsT16930","BRCC5","FANCR"],"biotype":"protein_coding","hgnc_id":"HGNC:9817","gene_name":"RAD51 recombinase","omim_gene":["179617"],"alias_name":["BRCA1/BRCA2-containing complex, subunit 5"],"gene_symbol":"RAD51","hgnc_symbol":"RAD51","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"15:40986972-41024354","ensembl_id":"ENSG00000051180"}},"GRch38":{"90":{"location":"15:40694774-40732339","ensembl_id":"ENSG00000051180"}}},"hgnc_date_symbol_changed":"1993-05-26"},"entity_type":"gene","entity_name":"RAD51","confidence_level":"1","penetrance":"Complete","mode_of_pathogenicity":"","publications":["22305526","21242494"],"evidence":["Expert Review Red"],"phenotypes":["Mirror movements 2,614508"],"mode_of_inheritance":"MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","tags":[],"panel":{"id":285,"hash_id":"558aa423bb5a16630e15b63c","name":"Intellectual disability","disease_group":"Neurology and neurodevelopmental disorders","disease_sub_group":"Neurodevelopmental disorders","status":"public","version":"2.1065","version_created":"2019-10-07T13:42:16.019766Z","relevant_disorders":["Coarse facial features including Coffin-Siris-like disorders","ID","Moderate","severe or profound intellectual disability","Schizophrenia plus additional features","Intellectual disability - microarray","fragile X and sequencing"],"stats":{"number_of_genes":2253,"number_of_strs":11,"number_of_regions":57},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."},{"name":"Component Of Super Panel","slug":"component-of-super-panel","description":"This panel is a component of a Super Panel"}]}}]}