{"count":1,"next":null,"previous":null,"results":[{"gene_data":{"alias":["PGIS","CYP8A1"],"biotype":"protein_coding","hgnc_id":"HGNC:9603","gene_name":"prostaglandin I2 synthase","omim_gene":["601699"],"alias_name":["cytochrome P450, family 8, subfamily A, polypeptide 1","prostacyclin synthase"],"gene_symbol":"PTGIS","hgnc_symbol":"PTGIS","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"20:48120411-48184683","ensembl_id":"ENSG00000124212"}},"GRch38":{"90":{"location":"20:49503874-49568146","ensembl_id":"ENSG00000124212"}}},"hgnc_date_symbol_changed":"1994-07-28"},"entity_type":"gene","entity_name":"PTGIS","confidence_level":"1","penetrance":"Complete","mode_of_pathogenicity":"","publications":[],"evidence":["Expert Review Red","Radboud University Medical Center, Nijmegen"],"phenotypes":["Hypertension, essential, 145500"],"mode_of_inheritance":"Other - please specifiy in evaluation comments","tags":[],"panel":{"id":314,"hash_id":"553f9697bb5a1616e5ed45d4","name":"Extreme early-onset hypertension","disease_group":"Renal and urinary tract disorders","disease_sub_group":"Disorders of function","status":"public","version":"1.10","version_created":"2018-12-16T17:33:34.572280Z","relevant_disorders":[],"stats":{"number_of_genes":25,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."}]}}]}