{"count":2,"next":null,"previous":null,"results":[{"gene_data":{"alias":["GM"],"biotype":"protein_coding","hgnc_id":"HGNC:9291","gene_name":"protein phosphatase 1 regulatory subunit 3A","omim_gene":["600917"],"alias_name":["glycogen-associated regulatory subunit of protein phosphatase-1","protein phosphatase 1 regulatory subunit GM"],"gene_symbol":"PPP1R3A","hgnc_symbol":"PPP1R3A","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"7:113516832-113715975","ensembl_id":"ENSG00000154415"}},"GRch38":{"90":{"location":"7:113876777-114075920","ensembl_id":"ENSG00000154415"}}},"hgnc_date_symbol_changed":"2001-07-02"},"entity_type":"gene","entity_name":"PPP1R3A","confidence_level":"1","penetrance":"Complete","mode_of_pathogenicity":"","publications":[],"evidence":["Expert Review Red","Radboud University Medical Center, Nijmegen"],"phenotypes":["Insulin resistance, severe, digenic\t125853"],"mode_of_inheritance":"MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","tags":[],"panel":{"id":174,"hash_id":"55b2109c22c1fc7dd7ce411f","name":"Insulin resistance (including lipodystrophy)","disease_group":"Endocrine disorders","disease_sub_group":"Disorders of unusual phenotypes","status":"public","version":"1.11","version_created":"2019-06-20T15:15:09.915719Z","relevant_disorders":["Insulin resistance (including lipodystrophy"],"stats":{"number_of_genes":26,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"}]}},{"gene_data":{"alias":["GM"],"biotype":"protein_coding","hgnc_id":"HGNC:9291","gene_name":"protein phosphatase 1 regulatory subunit 3A","omim_gene":["600917"],"alias_name":["glycogen-associated regulatory subunit of protein phosphatase-1","protein phosphatase 1 regulatory subunit GM"],"gene_symbol":"PPP1R3A","hgnc_symbol":"PPP1R3A","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"7:113516832-113715975","ensembl_id":"ENSG00000154415"}},"GRch38":{"90":{"location":"7:113876777-114075920","ensembl_id":"ENSG00000154415"}}},"hgnc_date_symbol_changed":"2001-07-02"},"entity_type":"gene","entity_name":"PPP1R3A","confidence_level":"0","penetrance":null,"mode_of_pathogenicity":"","publications":[],"evidence":["Expert Review Removed"],"phenotypes":["Insulin resistance, severe, digenic"],"mode_of_inheritance":"MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","tags":[],"panel":{"id":472,"hash_id":null,"name":"Monogenic diabetes","disease_group":"","disease_sub_group":"","status":"public","version":"2.1","version_created":"2019-07-31T13:20:07.800002Z","relevant_disorders":["R141"],"stats":{"number_of_genes":77,"number_of_strs":0,"number_of_regions":1},"types":[{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."},{"name":"GMS signed-off","slug":"gms-signed-off","description":"This panel has undergone review by a NHSE GMS disease specialist group and processes to be signed-off for use within the GMS."}]}}]}
