{"count":1,"next":null,"previous":null,"results":[{"gene_data":{"alias":["POF","FLJ22792"],"biotype":"protein_coding","hgnc_id":"HGNC:13711","gene_name":"POF1B, actin binding protein","omim_gene":["300603"],"alias_name":null,"gene_symbol":"POF1B","hgnc_symbol":"POF1B","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"X:84532402-84634748","ensembl_id":"ENSG00000124429"}},"GRch38":{"90":{"location":"X:85277396-85379743","ensembl_id":"ENSG00000124429"}}},"hgnc_date_symbol_changed":"2004-06-01"},"entity_type":"gene","entity_name":"POF1B","confidence_level":"2","penetrance":"Complete","mode_of_pathogenicity":"","publications":["16773570","26243799"],"evidence":["Expert Review Amber","Illumina TruGenome Clinical Sequencing Services","Radboud University Medical Center, Nijmegen","Expert list"],"phenotypes":["premature ovarian failure","Premature ovarian failure 2B,300604","Premature Ovarian Failure 2B"],"mode_of_inheritance":"X-LINKED: hemizygous mutation in males, biallelic mutations in females","tags":[],"panel":{"id":155,"hash_id":"575ed2398f62034208b69ee1","name":"Primary ovarian insufficiency","disease_group":"Endocrine disorders","disease_sub_group":"Gonadal and sex development disorders","status":"public","version":"1.16","version_created":"2019-06-20T15:13:53.581309Z","relevant_disorders":["Early onset familial premature ovarian insufficiency","Early onset familial premature ovarian failure"],"stats":{"number_of_genes":56,"number_of_strs":1,"number_of_regions":0},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."}]}}]}