{"count":4,"next":null,"previous":null,"results":[{"gene_data":{"alias":["GPI-MT-I"],"biotype":"protein_coding","hgnc_id":"HGNC:18858","gene_name":"phosphatidylinositol glycan anchor biosynthesis class M","omim_gene":["610273"],"alias_name":["GPI mannosyltransferase 1","DPM:GlcN-(acyl-)PI mannosyltransferase","dol-P-Man dependent GPI mannosyltransferase"],"gene_symbol":"PIGM","hgnc_symbol":"PIGM","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"1:159997462-160001783","ensembl_id":"ENSG00000143315"}},"GRch38":{"90":{"location":"1:160027673-160031991","ensembl_id":"ENSG00000143315"}}},"hgnc_date_symbol_changed":"2002-07-05"},"entity_type":"gene","entity_name":"PIGM","confidence_level":"2","penetrance":"Complete","mode_of_pathogenicity":"","publications":["27604308","16767100","25293775"],"evidence":["Expert Review Amber","Radboud University Medical Center, Nijmegen","Literature"],"phenotypes":["Glycosylphosphatidylinositol deficiency, 610293","Hypercoagulability syndrome due to glycosylphosphatidylinositol deficiency","Disorders of glycosphingolipid and glycosylphosphatidylinositol anchor glycosylation"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":["promoter"],"panel":{"id":25,"hash_id":"58346b8b8f62036225ca8a7d","name":"Congenital disorders of glycosylation","disease_group":"Metabolic disorders","disease_sub_group":"Specific metabolic abnormalities","status":"public","version":"1.32","version_created":"2019-10-07T16:15:06.398101Z","relevant_disorders":["Congential disorders of glycosylation"],"stats":{"number_of_genes":100,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"Component Of Super Panel","slug":"component-of-super-panel","description":"This panel is a component of a Super Panel"}]}},{"gene_data":{"alias":["GPI-MT-I"],"biotype":"protein_coding","hgnc_id":"HGNC:18858","gene_name":"phosphatidylinositol glycan anchor biosynthesis class M","omim_gene":["610273"],"alias_name":["GPI mannosyltransferase 1","DPM:GlcN-(acyl-)PI mannosyltransferase","dol-P-Man dependent GPI mannosyltransferase"],"gene_symbol":"PIGM","hgnc_symbol":"PIGM","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"1:159997462-160001783","ensembl_id":"ENSG00000143315"}},"GRch38":{"90":{"location":"1:160027673-160031991","ensembl_id":"ENSG00000143315"}}},"hgnc_date_symbol_changed":"2002-07-05"},"entity_type":"gene","entity_name":"PIGM","confidence_level":"2","penetrance":"Complete","mode_of_pathogenicity":"","publications":["27604308","16767100","25293775","17442906"],"evidence":["Expert Review Amber","Literature"],"phenotypes":["Glycosylphosphatidylinositol deficiency 610293"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":["promoter","curated-variant-list"],"panel":{"id":302,"hash_id":"5763f1518f620350a22bccdb","name":"Undiagnosed metabolic disorders","disease_group":"Metabolic disorders","disease_sub_group":"Specific metabolic abnormalities","status":"public","version":"1.373","version_created":"2019-10-08T14:47:17.153678Z","relevant_disorders":["Undiagnosed Metabolic Panel"],"stats":{"number_of_genes":744,"number_of_strs":1,"number_of_regions":1},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"}]}},{"gene_data":{"alias":["GPI-MT-I"],"biotype":"protein_coding","hgnc_id":"HGNC:18858","gene_name":"phosphatidylinositol glycan anchor biosynthesis class M","omim_gene":["610273"],"alias_name":["GPI mannosyltransferase 1","DPM:GlcN-(acyl-)PI mannosyltransferase","dol-P-Man dependent GPI mannosyltransferase"],"gene_symbol":"PIGM","hgnc_symbol":"PIGM","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"1:159997462-160001783","ensembl_id":"ENSG00000143315"}},"GRch38":{"90":{"location":"1:160027673-160031991","ensembl_id":"ENSG00000143315"}}},"hgnc_date_symbol_changed":"2002-07-05"},"entity_type":"gene","entity_name":"PIGM","confidence_level":"2","penetrance":null,"mode_of_pathogenicity":"","publications":["27604308","16767100","25293775","17442906"],"evidence":["Expert Review Amber","London North GLH","NHS GMS"],"phenotypes":["Glycosylphosphatidylinositol deficiency 610293"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":467,"hash_id":null,"name":"Inborn errors of metabolism","disease_group":"","disease_sub_group":"","status":"public","version":"1.348","version_created":"2019-10-09T08:19:52.386941Z","relevant_disorders":["Likely inborn error of metabolism - targeted testing not possible"],"stats":{"number_of_genes":877,"number_of_strs":2,"number_of_regions":1},"types":[{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."},{"name":"Component Of Super Panel","slug":"component-of-super-panel","description":"This panel is a component of a Super Panel"}]}},{"gene_data":{"alias":["GPI-MT-I"],"biotype":"protein_coding","hgnc_id":"HGNC:18858","gene_name":"phosphatidylinositol glycan anchor biosynthesis class M","omim_gene":["610273"],"alias_name":["GPI mannosyltransferase 1","DPM:GlcN-(acyl-)PI mannosyltransferase","dol-P-Man dependent GPI mannosyltransferase"],"gene_symbol":"PIGM","hgnc_symbol":"PIGM","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"1:159997462-160001783","ensembl_id":"ENSG00000143315"}},"GRch38":{"90":{"location":"1:160027673-160031991","ensembl_id":"ENSG00000143315"}}},"hgnc_date_symbol_changed":"2002-07-05"},"entity_type":"gene","entity_name":"PIGM","confidence_level":"1","penetrance":null,"mode_of_pathogenicity":"Other - please provide details in the comments","publications":["16767100"],"evidence":["DD-Gene2Phenotype","Expert Review Red"],"phenotypes":["Glycosylphosphatidylinositol deficiency"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":484,"hash_id":null,"name":"DDG2P","disease_group":"","disease_sub_group":"","status":"public","version":"1.137","version_created":"2019-10-08T15:56:59.220133Z","relevant_disorders":[],"stats":{"number_of_genes":1893,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"GMS Rare Disease","slug":"gms-rare-disease","description":"This panel type is used for GMS panels that are not virtual (i.e. could be a wet lab test)"},{"name":"Component Of Super Panel","slug":"component-of-super-panel","description":"This panel is a component of a Super Panel"}]}}]}