{"count":3,"next":null,"previous":null,"results":[{"gene_data":{"alias":["FLJ20303","TRM4","Misu"],"biotype":"protein_coding","hgnc_id":"HGNC:25994","gene_name":"NOP2/Sun RNA methyltransferase family member 2","omim_gene":["610916"],"alias_name":["tRNA methyltransferase 4 homolog (S. cerevisiae)","Myc-induced SUN-domain-containing protein"],"gene_symbol":"NSUN2","hgnc_symbol":"NSUN2","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"5:6599352-6633404","ensembl_id":"ENSG00000037474"}},"GRch38":{"90":{"location":"5:6599239-6633291","ensembl_id":"ENSG00000037474"}}},"hgnc_date_symbol_changed":"2004-08-25"},"entity_type":"gene","entity_name":"NSUN2","confidence_level":"2","penetrance":null,"mode_of_pathogenicity":"","publications":[],"evidence":["Expert Review Amber","PAGE DD-Gene2Phenotype"],"phenotypes":["AUTOSOMAL- RECESSIVE INTELLECTUAL DISABILITY MRT5"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":478,"hash_id":null,"name":"Fetal anomalies","disease_group":"","disease_sub_group":"","status":"public","version":"0.344","version_created":"2019-09-17T09:38:10.568007Z","relevant_disorders":["R21"],"stats":{"number_of_genes":1721,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."}]}},{"gene_data":{"alias":["FLJ20303","TRM4","Misu"],"biotype":"protein_coding","hgnc_id":"HGNC:25994","gene_name":"NOP2/Sun RNA methyltransferase family member 2","omim_gene":["610916"],"alias_name":["tRNA methyltransferase 4 homolog (S. cerevisiae)","Myc-induced SUN-domain-containing protein"],"gene_symbol":"NSUN2","hgnc_symbol":"NSUN2","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"5:6599352-6633404","ensembl_id":"ENSG00000037474"}},"GRch38":{"90":{"location":"5:6599239-6633291","ensembl_id":"ENSG00000037474"}}},"hgnc_date_symbol_changed":"2004-08-25"},"entity_type":"gene","entity_name":"NSUN2","confidence_level":"2","penetrance":null,"mode_of_pathogenicity":"Other - please provide details in the comments","publications":["22541562","22577224","22541559","21063731"],"evidence":["DD-Gene2Phenotype","Expert Review Amber"],"phenotypes":["AUTOSOMAL- RECESSIVE INTELLECTUAL DISABILITY MRT5 611091"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":484,"hash_id":null,"name":"DDG2P","disease_group":"","disease_sub_group":"","status":"public","version":"1.137","version_created":"2019-10-08T15:56:59.220133Z","relevant_disorders":[],"stats":{"number_of_genes":1893,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"GMS Rare Disease","slug":"gms-rare-disease","description":"This panel type is used for GMS panels that are not virtual (i.e. could be a wet lab test)"},{"name":"Component Of Super Panel","slug":"component-of-super-panel","description":"This panel is a component of a Super Panel"}]}},{"gene_data":{"alias":["FLJ20303","TRM4","Misu"],"biotype":"protein_coding","hgnc_id":"HGNC:25994","gene_name":"NOP2/Sun RNA methyltransferase family member 2","omim_gene":["610916"],"alias_name":["tRNA methyltransferase 4 homolog (S. cerevisiae)","Myc-induced SUN-domain-containing protein"],"gene_symbol":"NSUN2","hgnc_symbol":"NSUN2","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"5:6599352-6633404","ensembl_id":"ENSG00000037474"}},"GRch38":{"90":{"location":"5:6599239-6633291","ensembl_id":"ENSG00000037474"}}},"hgnc_date_symbol_changed":"2004-08-25"},"entity_type":"gene","entity_name":"NSUN2","confidence_level":"3","penetrance":"Complete","mode_of_pathogenicity":"","publications":[],"evidence":["Victorian Clinical Genetics Services","Expert Review Green","Radboud University Medical Center, Nijmegen","Illumina TruGenome Clinical Sequencing Services"],"phenotypes":["Mental Retardation, Recessive","Mental retardation, autosomal recessive 5, 611091","AUTOSOMAL- RECESSIVE INTELLECTUAL DISABILITY MRT5"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":285,"hash_id":"558aa423bb5a16630e15b63c","name":"Intellectual disability","disease_group":"Neurology and neurodevelopmental disorders","disease_sub_group":"Neurodevelopmental disorders","status":"public","version":"2.1065","version_created":"2019-10-07T13:42:16.019766Z","relevant_disorders":["Coarse facial features including Coffin-Siris-like disorders","ID","Moderate","severe or profound intellectual disability","Schizophrenia plus additional features","Intellectual disability - microarray","fragile X and sequencing"],"stats":{"number_of_genes":2253,"number_of_strs":11,"number_of_regions":57},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."},{"name":"Component Of Super Panel","slug":"component-of-super-panel","description":"This panel is a component of a Super Panel"}]}}]}
