{"count":1,"next":null,"previous":null,"results":[{"gene_data":{"alias":["SHP"],"biotype":"protein_coding","hgnc_id":"HGNC:7961","gene_name":"nuclear receptor subfamily 0 group B member 2","omim_gene":["604630"],"alias_name":null,"gene_symbol":"NR0B2","hgnc_symbol":"NR0B2","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"1:27237980-27240457","ensembl_id":"ENSG00000131910"}},"GRch38":{"90":{"location":"1:26911489-26913966","ensembl_id":"ENSG00000131910"}}},"hgnc_date_symbol_changed":"1999-08-19"},"entity_type":"gene","entity_name":"NR0B2","confidence_level":"1","penetrance":"Complete","mode_of_pathogenicity":"","publications":[],"evidence":["Expert list","Expert Review Red","Emory Genetics Laboratory","Radboud University Medical Center, Nijmegen"],"phenotypes":["Obesity, mild, early-onset, 601665","Congenital Obesity"],"mode_of_inheritance":"","tags":[],"panel":{"id":130,"hash_id":"55d2fc2d22c1fc2cc6635960","name":"Severe early-onset obesity","disease_group":"Endocrine disorders","disease_sub_group":"Obesity syndromes","status":"public","version":"2.0","version_created":"2019-09-23T12:02:23.516332Z","relevant_disorders":["Significant early-onset obesity with or without other endocrine features and short stature","Significant early-onset obesity +/- other endocrine features and short stature","R149"],"stats":{"number_of_genes":39,"number_of_strs":0,"number_of_regions":3},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."},{"name":"GMS Rare Disease","slug":"gms-rare-disease","description":"This panel type is used for GMS panels that are not virtual (i.e. could be a wet lab test)"},{"name":"GMS signed-off","slug":"gms-signed-off","description":"This panel has undergone review by a NHSE GMS disease specialist group and processes to be signed-off for use within the GMS."}]}}]}