{"count":7,"next":null,"previous":null,"results":[{"gene_data":{"alias":["bHLHd4","bHLHd5","bHLHd6","bHLHd7","bHLHd8"],"biotype":"protein_coding","hgnc_id":"HGNC:6913","gene_name":"MYC associated factor X","omim_gene":["154950"],"alias_name":null,"gene_symbol":"MAX","hgnc_symbol":"MAX","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"14:65472892-65569413","ensembl_id":"ENSG00000125952"}},"GRch38":{"90":{"location":"14:65006174-65102695","ensembl_id":"ENSG00000125952"}}},"hgnc_date_symbol_changed":"1992-10-27"},"entity_type":"gene","entity_name":"MAX","confidence_level":"3","penetrance":"Complete","mode_of_pathogenicity":"","publications":[],"evidence":["Expert Review Green","Expert list"],"phenotypes":["Neuroendocrine cancer"],"mode_of_inheritance":"MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","tags":[],"panel":{"id":183,"hash_id":"596f87dc8f620352d0e3eee2","name":"Neuroendocrine cancer pertinent cancer susceptibility","disease_group":"Cancer Programme","disease_sub_group":"Pertinent cancer susceptibility gene panel","status":"public","version":"1.0","version_created":"2017-11-05T02:37:20.183866Z","relevant_disorders":["phaeochromocytoma","paraganglioma","carcinoid","Neuroendocrine"],"stats":{"number_of_genes":12,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"Cancer Germline 100K","slug":"cancer-germline-100k","description":"Cancer Germline 100K"}]}},{"gene_data":{"alias":["bHLHd4","bHLHd5","bHLHd6","bHLHd7","bHLHd8"],"biotype":"protein_coding","hgnc_id":"HGNC:6913","gene_name":"MYC associated factor X","omim_gene":["154950"],"alias_name":null,"gene_symbol":"MAX","hgnc_symbol":"MAX","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"14:65472892-65569413","ensembl_id":"ENSG00000125952"}},"GRch38":{"90":{"location":"14:65006174-65102695","ensembl_id":"ENSG00000125952"}}},"hgnc_date_symbol_changed":"1992-10-27"},"entity_type":"gene","entity_name":"MAX","confidence_level":"3","penetrance":null,"mode_of_pathogenicity":null,"publications":[],"evidence":["Expert Review Green","Expert list"],"phenotypes":["Familial Pheochromocytoma, adrenal"],"mode_of_inheritance":"MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown","tags":[],"panel":{"id":391,"hash_id":null,"name":"Adult solid tumours for rare disease","disease_group":"Tumour syndromes","disease_sub_group":"Tumour syndromes","status":"public","version":"1.22","version_created":"2019-06-20T15:10:02.142139Z","relevant_disorders":["Young adult onset cancer","Exceptionally young adult onset cancer","Multiple Tumours","Rare tumour predisposition syndromes"],"stats":{"number_of_genes":58,"number_of_strs":0,"number_of_regions":1},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"}]}},{"gene_data":{"alias":["bHLHd4","bHLHd5","bHLHd6","bHLHd7","bHLHd8"],"biotype":"protein_coding","hgnc_id":"HGNC:6913","gene_name":"MYC associated factor X","omim_gene":["154950"],"alias_name":null,"gene_symbol":"MAX","hgnc_symbol":"MAX","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"14:65472892-65569413","ensembl_id":"ENSG00000125952"}},"GRch38":{"90":{"location":"14:65006174-65102695","ensembl_id":"ENSG00000125952"}}},"hgnc_date_symbol_changed":"1992-10-27"},"entity_type":"gene","entity_name":"MAX","confidence_level":"3","penetrance":null,"mode_of_pathogenicity":"","publications":[],"evidence":["Expert Review Green","Adult solid tumours for rare disease (Version 1.21)"],"phenotypes":["Familial Pheochromocytoma, adrenal"],"mode_of_inheritance":"MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown","tags":[],"panel":{"id":470,"hash_id":null,"name":"Tumour predisposition - adult onset","disease_group":"","disease_sub_group":"","status":"public","version":"1.1","version_created":"2019-06-20T15:14:23.703488Z","relevant_disorders":[],"stats":{"number_of_genes":63,"number_of_strs":0,"number_of_regions":2},"types":[{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."}]}},{"gene_data":{"alias":["bHLHd4","bHLHd5","bHLHd6","bHLHd7","bHLHd8"],"biotype":"protein_coding","hgnc_id":"HGNC:6913","gene_name":"MYC associated factor X","omim_gene":["154950"],"alias_name":null,"gene_symbol":"MAX","hgnc_symbol":"MAX","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"14:65472892-65569413","ensembl_id":"ENSG00000125952"}},"GRch38":{"90":{"location":"14:65006174-65102695","ensembl_id":"ENSG00000125952"}}},"hgnc_date_symbol_changed":"1992-10-27"},"entity_type":"gene","entity_name":"MAX","confidence_level":"3","penetrance":"Complete","mode_of_pathogenicity":"","publications":["PubMed: 21685915"],"evidence":["Expert Review Green","Emory Genetics Laboratory"],"phenotypes":["Endocrine Cancer"],"mode_of_inheritance":"MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","tags":[],"panel":{"id":36,"hash_id":"553f94b4bb5a1616e5ed4595","name":"Multiple endocrine tumours","disease_group":"Tumour syndromes","disease_sub_group":"Breast and endocrine","status":"public","version":"1.9","version_created":"2019-03-05T12:57:31.229789Z","relevant_disorders":["Multiple endocrine tumours","Multiple endocrine neoplasia type 1","Endocrine neoplasia"],"stats":{"number_of_genes":16,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"}]}},{"gene_data":{"alias":["bHLHd4","bHLHd5","bHLHd6","bHLHd7","bHLHd8"],"biotype":"protein_coding","hgnc_id":"HGNC:6913","gene_name":"MYC associated factor X","omim_gene":["154950"],"alias_name":null,"gene_symbol":"MAX","hgnc_symbol":"MAX","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"14:65472892-65569413","ensembl_id":"ENSG00000125952"}},"GRch38":{"90":{"location":"14:65006174-65102695","ensembl_id":"ENSG00000125952"}}},"hgnc_date_symbol_changed":"1992-10-27"},"entity_type":"gene","entity_name":"MAX","confidence_level":"3","penetrance":"Complete","mode_of_pathogenicity":"","publications":["PubMed: 21685915","22429592"],"evidence":["Expert Review Green","Eligibility statement prior genetic testing","Radboud University Medical Center, Nijmegen","Illumina TruGenome Clinical Sequencing Services","UKGTN","Emory Genetics Laboratory"],"phenotypes":["pheochromocytomas (PHEOs),  paragangliomas (PGLs)","Hereditary Paraganglioma-Pheochromocytoma Syndrome","{Pheochromocytoma, susceptibility to}, 171300"],"mode_of_inheritance":"MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","tags":[],"panel":{"id":97,"hash_id":"553f9599bb5a1616e5ed45b1","name":"Inherited phaeochromocytoma and paraganglioma","disease_group":"Tumour syndromes","disease_sub_group":"Breast and endocrine","status":"public","version":"1.5","version_created":"2019-03-05T14:07:55.639077Z","relevant_disorders":["Neuro-endocrine Tumours- PCC and PGL"],"stats":{"number_of_genes":20,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"}]}},{"gene_data":{"alias":["bHLHd4","bHLHd5","bHLHd6","bHLHd7","bHLHd8"],"biotype":"protein_coding","hgnc_id":"HGNC:6913","gene_name":"MYC associated factor X","omim_gene":["154950"],"alias_name":null,"gene_symbol":"MAX","hgnc_symbol":"MAX","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"14:65472892-65569413","ensembl_id":"ENSG00000125952"}},"GRch38":{"90":{"location":"14:65006174-65102695","ensembl_id":"ENSG00000125952"}}},"hgnc_date_symbol_changed":"1992-10-27"},"entity_type":"gene","entity_name":"MAX","confidence_level":"3","penetrance":null,"mode_of_pathogenicity":"","publications":["PubMed: 21685915","22429592"],"evidence":["Expert Review Green","NHS GMS"],"phenotypes":["{Pheochromocytoma, susceptibility to}, 171300","Hereditary Paraganglioma-Pheochromocytoma Syndrome","pheochromocytomas (PHEOs),  paragangliomas (PGLs)"],"mode_of_inheritance":"MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","tags":[],"panel":{"id":649,"hash_id":null,"name":"Inherited phaeochromocytoma and paraganglioma excluding NF1","disease_group":"","disease_sub_group":"","status":"public","version":"1.0","version_created":"2019-07-31T14:44:30.849339Z","relevant_disorders":["R223"],"stats":{"number_of_genes":12,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."},{"name":"GMS signed-off","slug":"gms-signed-off","description":"This panel has undergone review by a NHSE GMS disease specialist group and processes to be signed-off for use within the GMS."}]}},{"gene_data":{"alias":["bHLHd4","bHLHd5","bHLHd6","bHLHd7","bHLHd8"],"biotype":"protein_coding","hgnc_id":"HGNC:6913","gene_name":"MYC associated factor X","omim_gene":["154950"],"alias_name":null,"gene_symbol":"MAX","hgnc_symbol":"MAX","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"14:65472892-65569413","ensembl_id":"ENSG00000125952"}},"GRch38":{"90":{"location":"14:65006174-65102695","ensembl_id":"ENSG00000125952"}}},"hgnc_date_symbol_changed":"1992-10-27"},"entity_type":"gene","entity_name":"MAX","confidence_level":"3","penetrance":"Complete","mode_of_pathogenicity":"","publications":[],"evidence":["NHS GMS","Expert Review Green","Expert list"],"phenotypes":["Familial Pheochromocytoma, adrenal"],"mode_of_inheritance":"MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown","tags":[],"panel":{"id":245,"hash_id":"595ce30f8f62036352471f39","name":"Adult solid tumours cancer susceptibility","disease_group":"Cancer Programme","disease_sub_group":"Pertinent cancer susceptibility gene panel","status":"public","version":"1.7","version_created":"2019-08-13T09:55:08.772098Z","relevant_disorders":["Carcinoma of unknown primary","Other","Adult solid tumours pertinent cancer susceptibility"],"stats":{"number_of_genes":103,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"Cancer Germline 100K","slug":"cancer-germline-100k","description":"Cancer Germline 100K"},{"name":"GMS Cancer Germline Virtual","slug":"gms-cancer-germline-virtual","description":"This is a panel used for WGS germline analysis for the GMS."}]}}]}