{"count":2,"next":null,"previous":null,"results":[{"gene_data":{"alias":["Kv7.4"],"biotype":"protein_coding","hgnc_id":"HGNC:6298","gene_name":"potassium voltage-gated channel subfamily Q member 4","omim_gene":["603537"],"alias_name":null,"gene_symbol":"KCNQ4","hgnc_symbol":"KCNQ4","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"1:41249684-41306124","ensembl_id":"ENSG00000117013"}},"GRch38":{"90":{"location":"1:40784012-40840452","ensembl_id":"ENSG00000117013"}}},"hgnc_date_symbol_changed":"1999-02-05"},"entity_type":"gene","entity_name":"KCNQ4","confidence_level":"1","penetrance":null,"mode_of_pathogenicity":null,"publications":["28787010"],"evidence":["Literature"],"phenotypes":[],"mode_of_inheritance":"","tags":[],"panel":{"id":394,"hash_id":null,"name":"Familial Meniere Disease","disease_group":"Hearing and ear disorders","disease_sub_group":"Other hearing and ear disorders","status":"public","version":"1.1","version_created":"2018-01-17T16:26:29.432517Z","relevant_disorders":[],"stats":{"number_of_genes":130,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"}]}},{"gene_data":{"alias":["Kv7.4"],"biotype":"protein_coding","hgnc_id":"HGNC:6298","gene_name":"potassium voltage-gated channel subfamily Q member 4","omim_gene":["603537"],"alias_name":null,"gene_symbol":"KCNQ4","hgnc_symbol":"KCNQ4","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"1:41249684-41306124","ensembl_id":"ENSG00000117013"}},"GRch38":{"90":{"location":"1:40784012-40840452","ensembl_id":"ENSG00000117013"}}},"hgnc_date_symbol_changed":"1999-02-05"},"entity_type":"gene","entity_name":"KCNQ4","confidence_level":"3","penetrance":"Complete","mode_of_pathogenicity":"","publications":["26036578","16437162","10025409","10080176","10369879","10571947","10760249","10760300","10925378","11450843","12112653","12670425","16596322","18030493","20966080","8035838","9126484"],"evidence":["Expert Review Green","Radboud University Medical Center, Nijmegen","UKGTN","Emory Genetics Laboratory"],"phenotypes":["#600101:Deafness, autosomal dominant 2A"],"mode_of_inheritance":"BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal","tags":["watchlist"],"panel":{"id":126,"hash_id":"558ac48fbb5a16630dcfeaad","name":"Hearing loss","disease_group":"Hearing and ear disorders","disease_sub_group":"Non-syndromic hearing loss","status":"public","version":"2.2","version_created":"2019-09-03T14:01:56.987667Z","relevant_disorders":["Congenital hearing impairment","Autosomal dominant deafness","Congenital hearing impairment (profound/severe)","R67"],"stats":{"number_of_genes":358,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."},{"name":"GMS signed-off","slug":"gms-signed-off","description":"This panel has undergone review by a NHSE GMS disease specialist group and processes to be signed-off for use within the GMS."},{"name":"GMS Rare Disease","slug":"gms-rare-disease","description":"This panel type is used for GMS panels that are not virtual (i.e. could be a wet lab test)"}]}}]}