{"count":3,"next":null,"previous":null,"results":[{"gene_data":{"alias":["LFA-1","MAC-1"],"biotype":"protein_coding","hgnc_id":"HGNC:6155","gene_name":"integrin subunit beta 2","omim_gene":["600065"],"alias_name":["complement component 3 receptor 3 and 4 subunit"],"gene_symbol":"ITGB2","hgnc_symbol":"ITGB2","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"21:46305868-46351904","ensembl_id":"ENSG00000160255"}},"GRch38":{"90":{"location":"21:44885953-44931989","ensembl_id":"ENSG00000160255"}}},"hgnc_date_symbol_changed":"1986-01-01"},"entity_type":"gene","entity_name":"ITGB2","confidence_level":"3","penetrance":"Complete","mode_of_pathogenicity":"","publications":[],"evidence":["UKGTN","Radboud University Medical Center, Nijmegen","Illumina TruGenome Clinical Sequencing Services","Expert list"],"phenotypes":["Leukocyte adhesion deficiency 116920"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":176,"hash_id":"56ba026c22c1fc5025762b50","name":"Infantile enterocolitis & monogenic inflammatory bowel disease","disease_group":"Gastroenterological disorders","disease_sub_group":"Gastrointestinal disorders","status":"public","version":"1.16","version_created":"2017-11-05T02:37:20.171671Z","relevant_disorders":["Infantile enterocolitis and monogenic inflammatory bowel disease"],"stats":{"number_of_genes":62,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"}]}},{"gene_data":{"alias":["LFA-1","MAC-1"],"biotype":"protein_coding","hgnc_id":"HGNC:6155","gene_name":"integrin subunit beta 2","omim_gene":["600065"],"alias_name":["complement component 3 receptor 3 and 4 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deficiency, 116920","LAD","Leukocyte adhesion deficiency type I","Delayed cord separation, skin ulcers, periodontitis, leukocytosis","Congenital defects of phagocyte number or function"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":398,"hash_id":null,"name":"Primary immunodeficiency","disease_group":"","disease_sub_group":"","status":"public","version":"1.132","version_created":"2019-09-27T14:37:49.085568Z","relevant_disorders":["Primary immunodeficiency disorders","A- or hypo-gammaglobulinaemia","Congenital neutropaenia","Agranulocytosis","Combined B and T cell defect","Inherited complement deficiency","SCID","Primary immune disorder","Primary immunodeficiency","A-gammaglobulinaemia","Agammaglobulinaemia","hypo-gammaglobulinaemia","hypogammaglobulinemia","immune deficiency syndromes","Severe combined immunodeficiency","Congenital neutopenia","Familial haemophagocytic lymphohistiocytic disorders","Familial hemophagocytic lymphohistiocytic 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