{"count":2,"next":null,"previous":null,"results":[{"gene_data":{"alias":["KIAA1259","Ino80","hINO80","INO80A"],"biotype":"protein_coding","hgnc_id":"HGNC:26956","gene_name":"INO80 complex subunit","omim_gene":["610169"],"alias_name":["INO80 complex subunit A"],"gene_symbol":"INO80","hgnc_symbol":"INO80","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"15:41271078-41408552","ensembl_id":"ENSG00000128908"}},"GRch38":{"90":{"location":"15:40978880-41116354","ensembl_id":"ENSG00000128908"}}},"hgnc_date_symbol_changed":"2008-08-07"},"entity_type":"gene","entity_name":"INO80","confidence_level":"3","penetrance":null,"mode_of_pathogenicity":null,"publications":["25883595","25312759"],"evidence":["NHS GMS","North West GLH","London North GLH","IUIS Classification February 2018","Victorian Clinical Genetics Services","Expert Review Green","GRID V2.0"],"phenotypes":["INO80 deficiency, HIGM","severe bacterial infections","Severe bacterial infections","Predominantly Antibody Deficiencies"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":398,"hash_id":null,"name":"Primary immunodeficiency","disease_group":"","disease_sub_group":"","status":"public","version":"1.132","version_created":"2019-09-27T14:37:49.085568Z","relevant_disorders":["Primary immunodeficiency disorders","A- or hypo-gammaglobulinaemia","Congenital neutropaenia","Agranulocytosis","Combined B and T cell defect","Inherited complement deficiency","SCID","Primary immune disorder","Primary immunodeficiency","A-gammaglobulinaemia","Agammaglobulinaemia","hypo-gammaglobulinaemia","hypogammaglobulinemia","immune deficiency syndromes","Severe combined immunodeficiency","Congenital neutopenia","Familial haemophagocytic lymphohistiocytic disorders","Familial hemophagocytic lymphohistiocytic disorders","PID","Sepsis","Disseminated non-tuberculous mycobacterial infection","R15"],"stats":{"number_of_genes":395,"number_of_strs":0,"number_of_regions":2},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."}]}},{"gene_data":{"alias":["KIAA1259","Ino80","hINO80","INO80A"],"biotype":"protein_coding","hgnc_id":"HGNC:26956","gene_name":"INO80 complex subunit","omim_gene":["610169"],"alias_name":["INO80 complex subunit A"],"gene_symbol":"INO80","hgnc_symbol":"INO80","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"15:41271078-41408552","ensembl_id":"ENSG00000128908"}},"GRch38":{"90":{"location":"15:40978880-41116354","ensembl_id":"ENSG00000128908"}}},"hgnc_date_symbol_changed":"2008-08-07"},"entity_type":"gene","entity_name":"INO80","confidence_level":"1","penetrance":null,"mode_of_pathogenicity":null,"publications":["25558065"],"evidence":["Wessex and West Midlands GLH","NHS GMS","Expert Review Red","Literature"],"phenotypes":["Intellectual disability, epilepsy and primary microcephaly"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":402,"hash_id":null,"name":"Genetic epilepsy syndromes","disease_group":"Neurology and neurodevelopmental disorders","disease_sub_group":"Inherited Epilepsy Syndromes","status":"public","version":"1.363","version_created":"2019-10-08T10:06:11.607307Z","relevant_disorders":["Epilepsy Plus","Epilepsy plus other features","Genetic Epilepsy Syndromes","Epileptic encephalopathy","Familial Focal Epilepsies","Familial Genetic Generalised Epilepsies","Genetic Epilepsies with Febrile Seizures Plus (GEFS+)","Genetic Epilepsies with Febrile Seizures Plus"],"stats":{"number_of_genes":614,"number_of_strs":2,"number_of_regions":13},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease","slug":"gms-rare-disease","description":"This panel type is used for GMS panels that are not virtual (i.e. could be a wet lab test)"},{"name":"Component Of Super Panel","slug":"component-of-super-panel","description":"This panel is a component of a Super Panel"}]}}]}